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Daniel Webster Fults, III, M.D.

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Specialties

Languages

  • English
  • German
  • Spanish

Clinical Details

Schedule An Appointment Clinical Office Address
(801) 585-6065 Clinical Neurosciences Center
175 North Medical Drive East
Salt Lake City, UT 84132
Map

Bio

Daniel W. Fults III, MD is Professor of Neurosurgery at the University of Utah and is a member of Huntsman Cancer Institute’s Brain Tumor Program. As a physician-researcher, Dr. Fults’s clinical practice is centered on brain tumor treatment. Malignant brain tumors found in children is the primary focus of his laboratory research.

Board Certification and Academic Information

Academic Departments Neurosurgery - Professor
Oncological Sciences - Adjunct Professor
Academic Divisions Adult Neurosurgery
Board Certification American Board of Neurological Surgery (Neurosurg)
Cancer Center Programs Cell Response & Regulation

Academic Profile

Research Interests

  • Medulloblastoma
  • Molecular Biology
  • Childhood Cancer
  • Surgery for Brain Tumors

Board Certification and Academic Information

Academic Departments Neurosurgery - Professor
Oncological Sciences - Adjunct Professor
Academic Divisions Adult Neurosurgery
Board Certification American Board of Neurological Surgery (Neurosurg)
Cancer Center Programs Cell Response & Regulation

Academic Office Locations

Academic Office Phone Number Academic Office Address
(801) 581-6908 Clinical Neurosciences Center
Department of Neurosurgery
175 North Medical Drive East
Salt Lake City, UT 84132
Huntsman Cancer Institute
2000 Circle of Hope
Salt Lake City, UT 84112

Academic Bio

Dr. Fults is Professor of Neurosurgery and Oncological Sciences at the University of Utah and holder of the M. Peter and Robyn Heilbrun endowed chair in neurosurgery. His is a board-certified neurosurgeon and a member of the brain tumor program at the Huntsman Cancer Institute. He is also an HCI investigator and member of the Cell Response and Regulation program. Dr. Fults is a clinician-scientist who has a long-standing commitment to the idea that advances in brain tumor treatment depend critically on understanding the molecular biology of this devastating disease. He has been the principal investigator of an NIH-funded research program in brain tumor biology for over 28 years.

Research in Dr. Fults’s laboratory is now focused on medulloblastoma, a malignant brain tumor that arises in the cerebellum in children. Aggressive treatments, combining surgery with radiation and chemotherapy, now offer children a 70% chance of being cured, but these harsh treatments carry a high risk of causing disabling neurological side effects, including neuropsychiatric challenges, stunted body growth, and hormonal imbalance, later in life. Hope for extending disease-free survival and eliminating treatment-related neurotoxicity rests on developing new treatments that specifically target the signaling molecules that drive medulloblastoma growth.

Dr. Fults studies how signaling molecules that normally govern the growth and differentiation of normal stem cells in the brain cause medulloblastoma. His experimental approach uses genetically engineered mice, in which genes can be transferred and expressed in stem cells in the brain. His research team discovered that activation of the Hedgehog signaling pathway, which is important in normal brain development, induces tumors in mice that closely resemble human medulloblastomas. In Dr. Fults’s lab, this mouse model is also used for preclinical testing of new therapies and for discovering the genes that cause medulloblastomas to metastasize to the spine, a condition that carries a grim prognosis for patients.

Education

Education History

Type School Degree
Fellowship University of North Carolina
Molecular Biology
Fellow
Residency Wake Forest University School of Medicine
Neurosurgery
Resident
Internship North Carolina Baptist Hospital
Surgery
Intern
Professional Medical University of Texas Southwestern Medical School
M.D.
Undergraduate University of Texas at Austin
Chemistry
B.S.

Publications

Selected Provider Publications

Clinical Trials

Video & News