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John R. Kestle, M.D.

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Clinical Details

Phone Number Clinical Office Address
(801) 662-5340
Primary Children's Hospital
Pediatric Neurosurgery
100 N Mario Capecchi Drive , Suite 1475
Salt Lake City, UT 84113

Bio

John R.W. Kestle, MD specializes in Craniofacial Surgery, Pediatric Neurosurgery, and Brain Tumors. Dr. Kestle is Professor of Neurosurgery and Vice Chair of Clinical Research. His clinical practice has been exclusively in pediatric neurosurgery, with a specific interest in pediatric epilepsy surgery. His research is centered on clinical trials methodology, which he developed a multi-center network for running clinical trials in pediatric neurosurgery. Dr. Kestle is also Chair of the Hydrocephalus Clinical Research Network.

Board Certification and Academic Information

Academic Departments Neurosurgery - Professor
Academic Divisions Pediatric Neurosurgery
Board Certification American Board of Pediatric Neurological Surgery
Royal College of Surgeons of Canada
American Board of Neurological Surgery (Neurosurg)

Academic Profile

Board Certification and Academic Information

Academic Departments Neurosurgery - Professor
Academic Divisions Pediatric Neurosurgery
Board Certification American Board of Pediatric Neurological Surgery
Royal College of Surgeons of Canada
American Board of Neurological Surgery (Neurosurg)

Academic Office Locations

Academic Office Phone Number Academic Office Address
(801) 662-5340 Primary Children's Hospital
Pediatric Neurosurgery
100 N Mario Capecchi Drive
Salt Lake City, UT 84113

Academic Bio

I am currently Professor of Neurosurgery and Vice Chair of Clinical Research at the University of Utah. My research career has always been clinical. I trained at McMaster University in Clinical Epidemiology and Biostatistics. Since the beginning of my career, I have been the Principal Investigator in a number of multicenter clinical trials in pediatric hydrocephalus and have trained 7 Pediatric Neurosurgery residents in clinical epidemiology and biostatistics (MPH training). In 2006, I co-founded the Hydrocephalus Clinical Research Network (HCRN). Although our previous trials had received peer reviewed funding (including the Medical Research Council of Canada when I practiced there), a research goal of mine had been to develop a collaborative network with infrastructure funding. We founded the HCRN in 2006, developed a philanthropic base to get us started, received NIH funding (RC1NS068943-01) in 2009 and currently have 17 investigators, 9 centers and 6 Network protocols running. My role has been development of the Network, recruitment of centers and investigators and mentoring of young investigators. Continued development of clinical research in the neurosciences, especially in hydrocephalus remains my highest academic priority.

Education

Education History

Type School Degree
Fellowship Hospital for Sick Children
Pediatric Neurosurgery
Fellow
Fellowship The Toronto Hospital
Peripheral Nerve Surgery
Fellow
Residency University of Toronto
Neurosurgery
Resident
Graduate Training McMaster University
Biostatistics and Epidemiology
M.S.
Internship St. Michael's Hospital
Surgery
Intern
Professional Medical University of Western Ontario
M.D.
Undergraduate University of Western Ontario
Biology
B.S.

Publications

Selected Provider Publications

Journal Article

  1. Park MS, Mazur MD, Moon K, Nanaszko MJ, Kestle JR, Shah LM, Winegar B, Albuquerque FC, Taussky P, McDougall CG (2016). An outcomes-based grading scale for the evaluation of cerebral aneurysms treated with flow diversion.LID - neurintsurg-2016-012688 [pii]LID - 10.1136/neurintsurg-2016-012688 [doi]. (Epub ahead of print) J Neurointerv Surg.
  2. Simon TD, Kronman MP, Whitlock KB, Gove N, Browd SR, Holubkov R, Kestle JR, Kulkarni AV, Langley M, Limbrick DD Jr, Luerssen TG, Oakes J, Riva-Cambrin J, Rozzelle C, Shannon C, Tamber M, Wellons JC 3rd, Whitehead WE, Mayer-Hamblett N (2016). Variability in Management of First Cerebrospinal Fluid Shunt Infection: A Prospective Multi-Institutional Observational Cohort Study.LID - S0022-3476(16)30877-0 [pii]LID - 10.1016/j.jpeds.2016.08.094 [doi]. (Epub ahead of print) J Pediatr.
  3. Johns D, Anstadt E, Donato D, Kestle J, Riva-Cambrin J, Siddiqi F, Gociman B (2016). Early Posterior Vault Distraction Osteogenesis for the Treatment of Syndromic Craniosynostosis. Craniomaxillofac Trauma Reconstr, 9(3), 219-23.
  4. Kulkarni AV, Riva-Cambrin J, Holubkov R, Browd SR, Cochrane DD, Drake JM, Limbrick DD, Rozzelle CJ, Simon TD, Tamber MS, Wellons JC 3rd, Whitehead WE, Kestle JR (2016). Endoscopic third ventriculostomy in children: prospective, multicenter results from the Hydrocephalus Clinical Research Network. J Neurosurg Pediatr, 1-7.
  5. Ravindra VM, Bollo RJ, Sivakumar W, Akbari H, Naftel RP, Limbrick DD Jr, Jea A, Gannon S, Shannon C, Birkas Y, Yang GL, Prather CT, Kestle JR, Riva-Cambrin J (2016). Predicting Blunt Cerebrovascular Injury in Pediatric Trauma: Validation of the "Utah Score". (Epub ahead of print) J Neurotrauma.
  6. Kestle JR, Holubkov R, Douglas Cochrane D, Kulkarni AV, Limbrick DD Jr, Luerssen TG, Jerry Oakes W, Riva-Cambrin J, Rozzelle C, Simon TD, Walker ML, Wellons JC 3rd, Browd SR, Drake JM, Shannon CN, Tamber MS, Whitehead WE (2016). A new Hydrocephalus Clinical Research Network protocol to reduce cerebrospinal fluid shunt infection. J Neurosurg Pediatr, 17(4), 391-6.
  7. Riva-Cambrin J, Kestle JR, Holubkov R, Butler J, Kulkarni AV, Drake J, Whitehead WE, Wellons JC 3rd, Shannon CN, Tamber MS, Limbrick DD Jr, Rozzelle C, Browd SR, Simon TD (2016). Risk factors for shunt malfunction in pediatric hydrocephalus: a multicenter prospective cohort study. J Neurosurg Pediatr, 17(4), 382-90.
  8. Steinbok P, Durity F, Kestle J, Cochrane DD (2015). Pediatric neurosurgery at British Columbia's Children's Hospital. Childs Nerv Syst, 31(9), 1419-27.
  9. McAllister JP 2nd, Williams MA, Walker ML, Kestle JR, Relkin NR, Anderson AM, Gross PH, Browd SR (2015). An update on research priorities in hydrocephalus: overview of the third National Institutes of Health-sponsored symposium "Opportunities for Hydrocephalus Research: Pathways to Better Outcomes". J Neurosurg, 123(6), 1427-38.
  10. Bowers C, Taussky P, Kestle JR, Park MS (2015). A Neurosurgical Call to Arms: Lessons from ARUBA, Mr. Clean, and the Hydrocephalus Clinical Research Network. World Neurosurg, 84(2), 202-4.
  11. Johns D, Blagg R, Kestle JR, Riva-Cambrin JK, Siddiqi F, Gociman B (2015). Distraction Osteogenesis Technique for the Treatment of Nonsyndromic Sagittal Synostosis. Plast Reconstr Surg Glob Open, 3(7), e474.
  12. Gopalakrishnan CV, Kestle JR, Connolly MB (2015). The "vagal ansa": a source of complication in vagus nerve stimulation. J Neurosurg Pediatr, 15(5), 535-8.
  13. Spader HS, Hertzler DA, Kestle JR, Riva-Cambrin J (2015). Risk factors for infection and the effect of an institutional shunt protocol on the incidence of ventricular access device infections in preterm infants. J Neurosurg Pediatr, 15(2), 156-60.
  14. Al-Tamimi YZ, Sinha P, Chumas PD, Crimmins D, Drake J, Kestle J, Hayward R, Solanki GA, Thomson S, Thorne J (2014). Ventriculoperitoneal shunt 30-day failure rate: a retrospective international cohort study. Neurosurgery, 74(1), 29-34.
  15. Gociman B, Blagg R, Agko M, Goodwin I, Kestle JR, Siddiqi F (2014). The metopic angle: a novel assessment tool of the trigonocephalic frontal deformity and its correction. J Craniofac Surg, 25(6), 2101-4.
  16. Kulkarni AV, Riva-Cambrin J, Browd SR, Drake JM, Holubkov R, Kestle JR, Limbrick DD, Rozzelle CJ, Simon TD, Tamber MS, Wellons JC 3rd, Whitehead WE (2014). Endoscopic third ventriculostomy and choroid plexus cauterization in infants with hydrocephalus: a retrospective Hydrocephalus Clinical Research Network study. J Neurosurg Pediatr, 14(3), 224-9.
  17. Whitehead WE, Riva-Cambrin J, Wellons JC 3rd, Kulkarni AV, Browd S, Limbrick D, Rozzelle C, Tamber MS, Simon TD, Shannon CN, Holubkov R, Oakes WJ, Luerssen TG, Walker ML, Drake JM, Kestle JR (2014). Factors associated with ventricular catheter movement and inaccurate catheter location: post hoc analysis of the hydrocephalus clinical research network ultrasound-guided shunt placement study. J Neurosurg Pediatr, 14(2), 173-8.
  18. Simon TD, Mayer-Hamblett N, Whitlock KB, Langley M, Kestle JR, Riva-Cambrin J, Rosenfeld M, Thorell EA (2014). Few Patient, Treatment, and Diagnostic or Microbiological Factors, Except Complications and Intermittent Negative Cerebrospinal Fluid (CSF) Cultures During First CSF Shunt Infection, Are Associated With Reinfection. J Pediatric Infect Dis Soc, 3(1), 15-22.
  19. Simon TD, Butler J, Whitlock KB, Browd SR, Holubkov R, Kestle JR, Kulkarni AV, Langley M, Limbrick DD Jr, Mayer-Hamblett N, Tamber M, Wellons JC 3rd, Whitehead WE, Riva-Cambrin J (2014). Risk factors for first cerebrospinal fluid shunt infection: findings from a multi-center prospective cohort study. J Pediatr, 164(6), 1462-8.e2.
  20. Gross P, Reed GT, Engelmann R, Kestle JR (2014). Hydrocephalus research funding from the National Institutes of Health: a 10-year perspective. J Neurosurg Pediatr, 13(2), 145-50.
  21. Wellons JC 3rd, Holubkov R, Browd SR, Riva-Cambrin J, Whitehead W, Kestle J, Kulkarni AV (2013). The assessment of bulging fontanel and splitting of sutures in premature infants: an interrater reliability study by the Hydrocephalus Clinical Research Network. J Neurosurg Pediatr, 11(1), 12-4.
  22. Cress M, Kestle JR, Holubkov R, Riva-Cambrin J (2013). Risk factors for pediatric arachnoid cyst rupture/hemorrhage: a case-control study. Neurosurgery, 72(5), 716-22; discussion 722.
  23. Gociman B, Agko M, Blagg R, Garlick J, Kestle JR, Siddiqi F (2013). Endoscopic-assisted correction of metopic synostosis. J Craniofac Surg, 24(3), 763-8.
  24. Kalra RR, Kestle JR (2013). An assessment of academic productivity in pediatric neurosurgery. J Neurosurg Pediatr, 12(3), 262-5.
  25. Kulkarni AV, Riva-Cambrin J, Butler J, Browd SR, Drake JM, Holubkov R, Kestle JR, Limbrick DD, Simon TD, Tamber MS, Wellons JC 3rd, Whitehead WE (2013). Outcomes of CSF shunting in children: comparison of Hydrocephalus Clinical Research Network cohort with historical controls: clinical article. J Neurosurg Pediatr, 12(4), 334-8.
  26. Whitehead WE, Riva-Cambrin J, Wellons JC 3rd, Kulkarni AV, Holubkov R, Illner A, Oakes WJ, Luerssen TG, Walker ML, Drake JM, Kestle JR (2013). No significant improvement in the rate of accurate ventricular catheter location using ultrasound-guided CSF shunt insertion: a prospective, controlled study by the Hydrocephalus Clinical Research Network. J Neurosurg Pediatr, 12(6), 565-74.
  27. Verma A, Zhou H, Chin S, Bruggers C, Kestle J, Khatua S (2012). EGFR as a predictor of relapse in myxopapillary ependymoma. Pediatr Blood Cancer, 59(4), 746-8.
  28. Simon TD, Whitlock KB, Riva-Cambrin J, Kestle JR, Rosenfeld M, Dean JM, Holubkov R, Langley M, Mayer-Hamblett N (2012). Association of intraventricular hemorrhage secondary to prematurity with cerebrospinal fluid shunt surgery in the first year following initial shunt placement. J Neurosurg Pediatr, 9(1), 54-63.
  29. Brockmeyer DL, Ragel BT, Kestle JR (2012). The pediatric cervical spine instability study. A pilot study assessing the prognostic value of four imaging modalities in clearing the cervical spine for children with severe traumatic injuries. Childs Nerv Syst, 28(5), 699-705.
  30. Simon TD, Whitlock KB, Riva-Cambrin J, Kestle JR, Rosenfeld M, Dean JM, Holubkov R, Langley M, Hamblett NM (2012). Revision surgeries are associated with significant increased risk of subsequent cerebrospinal fluid shunt infection. Pediatr Infect Dis J, 31(6), 551-6.
  31. Riva-Cambrin J, Shannon CN, Holubkov R, Whitehead WE, Kulkarni AV, Drake J, Simon TD, Browd SR, Kestle JR, Wellons JC 3rd (2012). Center effect and other factors influencing temporization and shunting of cerebrospinal fluid in preterm infants with intraventricular hemorrhage. J Neurosurg Pediatr, 9(5), 473-81.
  32. Gociman B, Marengo J, Ying J, Kestle JR, Siddiqi F (2012). Minimally invasive strip craniectomy for sagittal synostosis. J Craniofac Surg, 23(3), 825-8.
  33. Brockmeyer DL, Ragel BT, Kestle J (2012). The Pediatric Cervical Spine Instability Study: a pilot study assessing the prognostic value of four imaging modalities in clearing the cervical spine for children with severe traumatic injuries. Childs Nerv Syst, 28(5), 699-705.
  34. Yong RL, Habrock-Bach T, Vaughan M, Kestle JR, Steinbok P (2011). Symptomatic retethering of the spinal cord after section of a tight filum terminale. Neurosurgery, 68(6), 1594-601; discussion 1601-2.
  35. Khatua S, Moore KR, Vats TS, Kestle JR (2011). Diffuse intrinsic pontine glioma-current status and future strategies. Childs Nerv Syst, 27(9), 1391-7.
  36. Kestle JR, Riva-Cambrin J, Wellons JC 3rd, Kulkarni AV, Whitehead WE, Walker ML, Oakes WJ, Drake JM, Luerssen TG, Simon TD, Holubkov R (2011). A standardized protocol to reduce cerebrospinal fluid shunt infection: the Hydrocephalus Clinical Research Network Quality Improvement Initiative. J Neurosurg Pediatr, 8(1), 22-9.
  37. Kestle JR (2011). The less you look, the less you find. J Neurosurg, 115(5), 1038-9; author reply 1039.
  38. Tuan TJ, Thorell EA, Hamblett NM, Kestle JR, Rosenfeld M, Simon TD (2011). Treatment and microbiology of repeated cerebrospinal fluid shunt infections in children. Pediatr Infect Dis J, 30(9), 731-5.
  39. Hutchison JS, Frndova H, Lo TY, Guerguerian AM, Hypothermia Pediatric Head Injury Trial Investigators, Canadian Critical Care Trials Group Kestle JR (2011). Impact of hypotension and low cerebral perfusion pressure on outcomes in children treated with hypothermia therapy following severe traumatic brain injury: a post hoc analysis of the Hypothermia Pediatric Head Injury Trial. Dev Neurosci, 32(5-6), 406-412.
  40. Adzick NS, Thom EA, Spong CY, Brock JW 3rd, Burrows PK, Johnson MP, Howell LJ, Farrell JA, Dabrowiak ME, Sutton LN, Gupta N, Tulipan NB, DAlton ME, Farmer DL, MOMS Investigators Kestle JR (2011). A randomized trial of prenatal versus postnatal repair of myelomeningocele. N Engl J Med, 364(11), 993-1004.
  41. Chen HH, Riva-Cambrin J, Brockmeyer D, Walker M, Kestle J (04/01/2011). Shunt failure due to intracranial migration of BioGlide® ventricular catheters. J Neurosurg Pediatr, 7(4), 408-412.
  42. Kulkarni AV, Drake JM, Kestle JR, Mallucci CL, Sgouros S, Constantini S (2010). Endoscopic third ventriculostomy vs cerebrospinal fluid shunt in the treatment of hydrocephalus in children: a propensity score-adjusted analysis. Neurosurgery, 67(3), 588-93.
  43. Simon TD, Hall M, Dean JM, Kestle JR, Riva-Cambrin J (2010). Reinfection following initial cerebrospinal fluid shunt infection. J Neurosurg Pediatr, 6(3), 277-85.
  44. Kulkarni AV, Drake JM, Kestle JR, Mallucci CL, Sgouros S, Constantini S (2010). Predicting who will benefit from endoscopic third ventriculostomy compared with shunt insertion in childhood hydrocephalus using the ETV Success Score. J Neurosurg Pediatr, 6(4), 310-5.
  45. Wellons JC, Shannon CN, Kulkarni AV, Simon TD, Riva-Cambrin J, Whitehead WE, Oakes WJ, Drake JM, Luerssen TG, Walker ML, Kestle JR (2009). A multicenter retrospective comparison of conversion from temporary to permanent cerebrospinal fluid diversion in very low birth weight infants with posthemorrhagic hydrocephalus. J Neurosurg Pediatr, 4(1), 50-5.
  46. Simon TD, Hall M, Riva-Cambrin J, Albert JE, Jeffries HE, Lafleur B, Dean JM, Kestle JR (2009). Infection rates following initial cerebrospinal fluid shunt placement across pediatric hospitals in the United States. Clinical article. J Neurosurg Pediatr, 4(2), 156-65.
  47. La Barge DV 3rd, Ng PP, Stevens EA, Friedline NK, Kestle JR, Schmidt RH (2009). Extended intracranial applications for ethylene vinyl alcohol copolymer (Onyx): mycotic and dissecting aneurysms. Technical note. J Neurosurg, 111(1), 114-8.
  48. Vachhrajani S, Kulkarni AV, Kestle JR (2009). Clinical practice guidelines. J Neurosurg Pediatr, 3(4), 249-56.
  49. Drake J, Kulkarni A, Kestle J (2009). Endoscopic third ventriculostomy versus ventriculoperitoneal shunt in pediatric patients: a decision analysis. Childs Nerv Syst, 25, 467-472.
  50. Kestle J (2008). Ventriculoperitoneal shunt in children: indications, equipment and techniques. Pan Arab Journal of Neurosurgery, 12(2), Supplement Ap.
  51. Simon TD, Riva-Cambrin J, Srivastava R, Bratton SL, Dean JM, Kestle JR (2008). Hospital care for children with hydrocephalus in the United States: utilization, charges, comorbidities, and deaths. J Neurosurg Pediatr, 1(2), 131-7.
  52. Kan P, Gooch J, Ploeger D, Grams B, Oberg W, Simonsen S, Walker ML, Kestle JRW (2008). Surgical treatment of spasticity in children: comparison of selective dorsal rhizotomy and intrathecal baclofen pump implantation. Childs Nerv Syst, 24, 239-243.
  53. Kan P, Simonsen SE, Lyon JL, Kestle JR (2008). Cellular phone use and brain tumor: a meta-analysis. J Neurooncol, 86(1), 71-8.
  54. Kan P, Van Orman C, Kestle JR (2008). Outcomes after surgery for focal epilepsy in children. Childs Nerv Syst, 24(5), 587-91.
  55. Williams MA, McAllister JP, Walker ML, Kranz DA, Bergsneider M, Del Bigio MR, Fleming L, Frim DM, Gwinn K, Kestle JR, Luciano MG, Madsen JR, Oster-Granite ML, Spinella G (2007). Priorities for hydrocephalus research: report from a National Institutes of Health-sponsored workshop. J Neurosurg, 107(5 Suppl), 345-57.
  56. Kan P, Walker ML, Drake JM, Kestle JR (2007). Predicting slitlike ventricles in children on the basis of baseline characteristics at the time of shunt insertion. J Neurosurg, 106(5 Suppl), 347-9.
  57. Binning M, Ragel B, Brockmeyer DL, Walker ML, Kestle JR (2007). Evaluation of the necessity of postoperative imaging after craniosynostosis surgery. J Neurosurg, 107(1 Suppl), 43-5.
  58. Kan P, Kestle J (2007). Lack of efficacy of antibiotic impregnated shunt systems in preventing shunt infections in children. Childs Nerv Syst, 23, 773-777.
  59. Kestle JR, Cochrane DD, Drake JM (2006). Shunt insertion in the summer: is it safe? J Neurosurg, 105(3 Suppl), 165-8.
  60. Kestle JR, Garton HJ, Whitehead WE, Drake JM, Kulkarni AV, Cochrane DD, Muszynski C, Walker ML (2006). Management of shunt infections: a multicenter pilot study. J Neurosurg, 105(3 Suppl), 177-81.
  61. Kan P, Amini A, Hansen K, White GL Jr, Brockmeyer DL, Walker ML, Kestle JR (2006). Outcomes after decompressive craniectomy for severe traumatic brain injury in children. J Neurosurg, 105(5 Suppl), 337-42.
  62. Kestle JRW, Cochrane DD, Drake JM (2006). Response to editorial: summer shunting. J Neurosurg, 105, 163-164.
  63. Kan P, Liu J, HedlundG, Brockmeyer D, Walker M, Kestle J (2006). The role of diffusion weighted MR imaging in pediatric brain tumors. Childs Nerv Syst, 22(11), 1435-1439.
  64. McCall T, Rao G, Kestle J (2006). Work hour restrictions: Impact on neurosurgical resident training at the University of Utah. AANS Bulletin, 14(4), 17-22.
  65. Klimo P Jr, Thompson CJ, Kestle JR, Schmidt MH (2005). A meta-analysis of surgery versus conventional radiotherapy for the treatment of metastatic spinal epidural disease. Neuro-Oncol, 7(1), 64-76.
  66. Kestle JR, Walker ML (2005). A multicenter prospective cohort study of the Strata valve for the management of hydrocephalus in pediatric patients. J Neurosurg, 102(2 Suppl), 141-5.
  67. Klimo P Jr, Kestle JR (2005). Potentially useful outcome measures for clinical research in pediatric neurosurgery. J Neurosurg, 103(3 Suppl), 207-12.
  68. Fassett D, Pingree J, Kestle J (2005). High incidence of tumor dissemination in myxopapillary ependymoma in children. J Neurosurg Pediatr, 102, 59-64.
  69. Kestle J, Townsend JJ, Brockmeyer DL, Walker ML (2004). Juvenile pilocytic astrocytoma of the brainstem in children. J Neurosurg, 101(1 Suppl), 1-6.
  70. Klimo P Jr, Thompson CJ, Drake J, Kestle JR (2004). Assessing the validity of the endoscopic shunt insertion trial: did surgical experience affect the results? J Neurosurg, 101(2 Suppl), 130-3.
  71. Anderson RC, Kan P, Klimo P, Brockmeyer DL, Walker ML, Kestle JR (2004). Complications of intracranial pressure monitoring in children with head trauma. J Neurosurg, 101(1 Suppl), 53-8.
  72. Liu JK, Tenner MS, Gottfried ON, Stevens EA, Rosenow JM, Madan N, MacDonald JD, Kestle JR, Couldwell WT (2004). Efficacy of multiple intraarterial papaverine infusions for improvement in cerebral circulation time in patients with recurrent cerebral vasospasm. J Neurosurg, 100(3), 414-21.
  73. Klimo P Jr, Kestle JR, MacDonald JD, Schmidt RH (2004). Marked reduction of cerebral vasospasm with lumbar drainage of cerebrospinal fluid after subarachnoid hemorrhage. J Neurosurg, 100(2), 215-24.
  74. Kestle J (2003). Tracking resident work hours. AANS Bulletin, 12, 49.
  75. Kestle JR, Drake JM, Cochrane DD, Milner R, Walker ML, Abbott R 3rd, Boop FA (2003). Lack of benefit of endoscopic ventriculoperitoneal shunt insertion: a multicenter randomized trial. J Neurosurg, 98(2), 284-90.
  76. Aldana PR, Kestle JR, Brockmeyer DL, Walker ML (2003). Results of endoscopic septal fenestration in the treatment of isolated ventricular hydrocephalus. Pediatr Neurosurg, 38(6), 286-94.
  77. Cochrane DD, Kestle JR (2003). The influence of surgical operative experience on the duration of first ventriculoperitoneal shunt function and infection. Pediatr Neurosurg, 38(6), 295-301.
  78. Klimo P Jr, Kestle JR, Schmidt MH (2003). Treatment of metastatic spinal epidural disease: a review of the literature. Neurosurg Focus, 15(5), E1.
  79. Arthur AS, Whitehead WE, Kestle JR (2002). Duration of antibiotic therapy for the treatment of shunt infection: a surgeon and patient survey. Pediatr Neurosurg, 36(5), 256-9.
  80. Hader WJ, Drake J, Cochrane D, Sparrow O, Johnson ES, Kestle J (2002). Death after late failure of third ventriculostomy in children. Report of three cases. J Neurosurg, 97(1), 211-5.
  81. Garton HJ, Kestle JR, Cochrane DD, Steinbok P (2002). A cost-effectiveness analysis of endoscopic third ventriculostomy. Neurosurgery, 51(1), 69-77; discussion 77-8.
  82. Hentschel S, Steinbok P, Cochrane DD, Kestle J (2002). Reduction of transfusion rates in the surgical correction of sagittal synostosis. J Neurosurg, 97(3), 503-9.
  83. Cochrane DD, Kestle J (2002). Ventricular shunting for hydrocephalus in children: patients, procedures, surgeons and institutions in English Canada, 1989-2001. Eur J Pediatr Surg, 12 Suppl 1, S6-11.
  84. Whitehead WE, Kestle JR (2001). The treatment of cerebrospinal fluid shunt infections. Results from a practice survey of the American Society of Pediatric Neurosurgeons. Pediatr Neurosurg, 35(4), 205-10.
  85. Garton HJ, Kestle JR, Drake JM (2001). Predicting shunt failure on the basis of clinical symptoms and signs in children. J Neurosurg, 94(2), 202-10.
  86. Tyagi A, Drake J, Midha R, Kestle J (2000). Axillary nerve injuries in children. Pediatr Neurosurg, 32(5), 226-9.
  87. Kestle J, Drake J, Milner R, Sainte-Rose C, Cinalli G, Boop F, Piatt J, Haines S, Schiff S, Cochrane D, Steinbok P, MacNeil N (2000). Long-term follow-up data from the Shunt Design Trial. Pediatr Neurosurg, 33(5), 230-236.
  88. Kestle J, Cochrane D, Alisharan R (2000). The initial treatment of hydrocephalus: an assessment of surgeons' preference between third ventriculostomy and shunt insertion. Neurol Res, 22(1), 65-8.
  89. Whitehead WE, MD, Riva-Cambrin J, Kulkarni AV, Wellons JC III, Rozzelle CJ, Tamber M, Limbrick DD, Browd S, Naftel R, Shannon C, Simon TD, Holubkov R, Illner A, Cochrane D, Drake JM, Luerssen TG, Oakes WJ, Kestle JRW, for the Hydrocephalus Clinical Research Network HCRN (In press). Ventricular catheter entry site and not catheter tip location predicts shunt survival: a secondary-analysis of three large pediatric hydrocephalus studies. J Neurosurg Pediatr.
  90. Guan J, Brock AA, Karsy M, Couldwell WT, Schmidt MH, Kestle J, Jensen RL, Dailey AT, Schmidt RH (In press). Managing concurrent surgery: An analysis of 1053 neurosurgical and spine cases. J Neurosurg.
  91. Walicke P, Abosch A, Asher A, Barker FG II, Harbaugh R, Jehi L, Kestle J, Koroshetz W, Little R, Rubin D, Valadka A, Wisniewski S, Chiocca EA, for the Workshop Participants (In Press). Launching effectiveness research to guide practice in neurosurgery: outcomes from an NINDS workshop report. J Neurosurg.

Review

  1. Ravindra VM, Kraus KL, Riva-Cambrin JK, Kestle JR (2015). The Need for Cost-Effective Neurosurgical Innovation-A Global Surgery Initiative. [Review]. World Neurosurgery, 84(5), 1458-61.
  2. Kan P, Kestle JR (2007). Designing randomized clinical trials in pediatric neurosurgery. [Review]. Child's Nervous System, 23(4), 385-90.
  3. Binning MJ, Liu JK, Kestle JR, Brockmeyer DL, Walker ML (2007). Optic pathway gliomas: a review. [Review]. Neurosurgical Focus, 23(5), E2.
  4. Drake J, Chumas P, Kestle J, Pierre-Kahn A, Vinchon M, Brown J, Pollack IF, Arai H (2006). Late rapid deterioration after endoscopic third ventriculostomy: additional cases and review of the literature. [Review]. Journal of Neurosurgery, 105(2 Suppl), 118-26.
  5. Browd SR, Ragel BT, Gottfried ON, Kestle JR (2006). Failure of cerebrospinal fluid shunts: part I: Obstruction and mechanical failure. [Review]. Pediatric Neurology, 34(2), 83-92.
  6. Browd SR, Gottfried ON, Ragel BT, Kestle JR (2006). Failure of cerebrospinal fluid shunts: part II: overdrainage, loculation, and abdominal complications. [Review]. Pediatric Neurology, 34(3), 171-6.
  7. Liu JK, Cole CD, Kestle JR, Brockmeyer DL, Walker ML (2005). Cranial base strategies for resection of craniopharyngioma in children. [Review]. Neurosurgical Focus, 18(6A), E9.
  8. Klimo P, Kestle J, Schmidt M (2004). Clinical trials and evidence based medicine for metastatic spine disease. [Review]. Neurosurgery Clinics of North America, 15(4), 549-564.
  9. Kestle JR (2003). Pediatric hydrocephalus: current management. [Review]. Neurologic Clinics, 21(4), 883-95, vii.
  10. Drake JM, Kestle JR, Tuli S (2000). CSF shunts 50 years on--past, present and future. [Review]. Child's Nervous System, 16(10-11), 800-4.
  11. Drake JM, Kestle JR, Tuli S (2000). Cerebrospinal fluid shunt technology. [Review]. Clinical Neurosurgery, 47, 336-45.

Book Chapter

  1. Sivakumar W, Ravindra VM, Riva-Cambrin J, Kestle JR (2015). Ventricular shunting for hydrocephalus. In Cohen A (Ed.), Pediatric Neurosurgery: Tricks of the Trade (pp. 316-). New York: Thieme.
  2. Garber S, Kestle JRW (2014). Brain stem tumors. In Berger M, Bernstein M (Eds.), Neuro-Oncology: The Essentials (3rd ed, Chapter 27). New York: Thieme.
  3. Kalra RS, Kestle J (2014). Treatment of hydrocephalus with shunts. In Albright A, Pollack I, Adelson D (Eds.), Principles and Practice of Pediatric Neurosurgery (3rd). New York: Thieme Medical Publishers.
  4. Kestle JR (2011). Hydrocephalus in children: Approach to the patient. In H.R. Winn (Ed.), Youman's Neurological Surgery (6th ed.). Philadelphia: Elsevier.
  5. Kestle J (2010). Tumors of the cranial vault in children. In Tonn J, Westphal M, Rutka J (Eds.), Oncology of CNS Tumors (2nd ed, Chapter 48, pp. 629-635). Berlin Heidelberg: Springer-Verlag.
  6. Wetjen N, Kestle J (2010). Peri-insular hemispherotomy. In Cateltepe O, Jallo G (Eds.), Pediatric Epilepsy Surgery: Preoperative Assessment and Surgical Treatment (Chapter 28, pp. 251-259). New York: Thieme Medical Publishers.
  7. Kestle JR (2009). Clinical trials in hydrocephalus: What have we learned? In Malucci C, Sgouros S, Abbott IR (Eds.), Cerebrospinal Fluid Disorders (Chapter 26, pp. 488-493). New York: Informa Healthcare.
  8. Kan P, Kestle JRW (2008). Brainstem tumors. In Berger M and Bernstein M (Eds.), Neuro-Oncology: The Essentials (2nd ed, Chapter 26, pp. 277-286). New York: Thieme.
  9. Anderson R, Garton H, Kestle JRW (2007). Treatment of hydrocephalus with shunts. In Albright A, Pollack I, Adelson D (Eds.), Principles and Practices in Pediatric Neurosurgery (2nd). New York: Thieme Medical Publishers.
  10. Browd S, Kestle J (2006). Peri-insular hemispherotomy. In Silbergeld D and Miller J (Eds.), Epilepsy Surgery: Principles and Controversies (pp. 585-588). Taylor and Francis Books.
  11. Rao G, Kestle J (2006). Calvarial tumors in children. In Tonn J, Westphal M, Grossman S, Rutka J (Eds.), Neuro-Oncology of CNS Tumors. Springer.
  12. Rao G, Kestle J (2005). Pleomorphic xanthoastrocytoma. In Berger M; Prados M (Ed.), Textbook of Neuro-Oncology. Philadelphia: Elsevier Saunders.
  13. Kestle J, Drake J (2004). Patterns of shunt failure according to the hydrodynamic features of the valve: Lessons from the Shunt Design Trial. In Cinalli G; Maixner W; Sainte-Rose C (Ed.), Pediatric Hydrocephalus. Milano: Springer-Verlag.
  14. Kestle J (2003). Communicating hydrocephalus. In Batjer H; Loftus C (Ed.), Textbook of Neurological Surgery. Philadelphia: Lippincott Williams & Wilkins.
  15. Kestle J (2001). Design of clinical trials. In McLone D; et al (Ed.), Pediatric Neurosurgery: Surgery of the Developing Nervous System. Philadelphia: W. B. Saunders.
  16. Ravindra VM, Sivakumar W, Riva-Cambrin JK, Kestle JR (In Press). Clinical management guidelines: pros and cons. In Good Paper, Successful Career: Guidelines for Biomedical Students, Residents and Researchers.
  17. Ravindra VM, Sivakumar W, Riva-Cambrin JK, Kestle JR (In Press). Clinical management guidelines: definition and development. In Good Paper, Successful Career: Guidelines for Biomedical Students, Residents and Researchers.
  18. Kestle JR (In Press). Hydrocephalus in children: etiology and overall management. In Winn H (Ed.), Youman's Neurological Surgery (7th ed.). Philadelphia: Elsevier.

Conference Proceedings

  1. Tamber M, Kulkarn A, Browd S, Shannon C, Rozzelle C, Cochrane D, Drake J, Riva-Cambrin J, Oakes WJ, Kestle J, Wellons J, Limbrick D, Holubkov R, Naftel R, Simon T, Luerssen T, Whitehead W (05/04/2016). Hydrocephalus Clinical Research Network (HCRN) Shunt Infection Protocol Implementation Across Pediatric Neurosurgery – A Cross-Sectional Survey. American Association of Neurological Surgeons/Congress of Neurological Surgeons Section on Pediatric Neurological Surgery, Chicago, IL.
  2. Simon TD, Kronman M, Whitlock K, Gove N, Browd S, Holubkov R, Kestle J, Kulkarni A, Langley M, Limbrick M, Luerssen T, Oakes J, Riva-Cambrin J, Rozzelle C, Shannon C, Tamber M, Wellons J, Whitehead W, Mayer-Hamblett N (05/01/2016). Adherence to guidelines in treatment for first cerebrospinal fluid (CSF) shunt infection. Pediatric Academic Society, 70, 2165-2168.
  3. Simon TD, Kronman M, Gove N, Whitlock K, Browd S, Holubkov R, Kestle J, Kulkarni A, Langley M, Limbrick D, Luerssen T, Oakes J, Riva-Cambrin J, Rozzelle C, Shannon C, Tamber M, Wellons J, Whitehead W, Hamblett N (05/03/2016). Surgical apparoch to treatment of first cerebrospinal fluid (CSF) shunt infection is associated with reinfection. Pediatric Academic Society, EPAS, 70, 4450-4457.

Case Report

  1. Rocque BG, George TM, Kestle J, Iskandar BJ (2011). Treatment practices for Chiari malformation type I with syringomyelia: results of a survey of the American Society of Pediatric Neurosurgeons. J Neurosurg Pediatr, 8(5), 430-7.
  2. McCall TD, Liu JK, Kestle JR (2006). Sporadic osteochondroma of the cervical spine. Case illustration. J Neurosurg, 104(4 Suppl), 293.
  3. Binning MJ, Ragel BT, Walker ML, Kestle JR (2006). Retained peritoneal shunt tubing causing hematuria. Case illustration. J Neurosurg, 104(6 Suppl), 434.
  4. Amini A, Liu JK, Kestle JR (2006). Disseminated medulloblastoma. J Neurooncol, 80(2), 157-8.
  5. Fassett DR, Pingree J, Kestle JR (2005). The high incidence of tumor dissemination in myxopapillary ependymoma in pediatric patients. Report of five cases and review of the literature. J Neurosurg, 102(1 Suppl), 59-64.
  6. Liu JK, Cole CD, Sherr GT, Kestle JR, Walker ML (2005). Noncommunicating spinal extradural arachnoid cyst causing spinal cord compression in a child. J Neurosurg, 103(3 Suppl), 266-9.
  7. Anderson RC, Walker ML, Viner JM, Kestle JR (2004). Adjustment and malfunction of a programmable valve after exposure to toy magnets. Case report. J Neurosurg, 101(2 Suppl), 222-5.
  8. Gluf WM, Kestle JR (2002). 'Cortical thumb sign' in X-linked hydrocephalus. Pediatr Neurosurg, 37(2), 107-8.

Editorial

  1. Kestle JR (2016). Editorial: The learning curve in surgical randomized controlled trials. J Neurosurg Pediatr, 18(2), 145.
  2. Kestle JRW (2016). Editorial: The challenges of determining natural history. J Neurosurg Pediatr, 17(2), 121-122.
  3. Kestle JR (2015). Editorial: Measuring resident operative skills. J Neurosurg Pediatr, 1-2.
  4. Kestle JR (2015). Editorial: Bed rest after filum surgery. J Neurosurg Pediatr, 15(5), 459; discussion 460.
  5. Kestle JR (2015). Editorial: Food and Drug Administration Safety Communication on rhBMP-2 use. J Neurosurg Pediatr, 16(1), 1-3.
  6. Kestle JR (2015). Editorial: industry-sponsored research. J Neurosurg, 122(1), 136-8.
  7. Kestle JR (2015). Administrative database research. J Neurosurg, 122(2), 441-2.
  8. Kestle JRW (2014). Counterpoint: Shunts Are Not Going Away So We Need to Do Them Well. AANS Neurosurgeon, 23(1).
  9. Kestle JR (2013). Shunt insertion. J Neurosurg, 119(1), 64.
  10. Kestle JR (2012). Editorial: intraventricular hemorrhage and posthemorrhagic hydrocephalus. J Neurosurg Pediatr, 9(3), 239-40; discussion 240-1.
  11. Kestle JR (2012). Retethering after filum cutting. World Neurosurg, 77(1), 82.
  12. Kestle JR (2012). Abdominal binders. J Neurosurg Pediatr, 9(6), 613; discussion 614.
  13. Kestle J (2011). The less you look, the less you find. J Neurosurg, 115(5), 1038-1039.
  14. Kestle JR (2011). Pooling data on antibiotic-impregnated shunts. J Neurosurg Pediatr, 8(3), 257-8; discussion 258.
  15. Kestle JR (2010). Antibiotic-impregnated external ventricular drains. J Neurosurg, 113(1), 85; discussion 85.
  16. Kestle JR (2010). Shunt malfunction. J Neurosurg, 113(6), 1270-1; discussion 1271-2.
  17. Kestle JR (2008). It's randomized and double blinded... what more do we want? J Neurosurg Pediatr, 2(2), 109; discussion 110.

Letter

  1. Riva-Cambrin J, Kestle JRW, Simon TD, The Hydrocephalus Clinical Research Network (2016). Author's response to editorial [Letter to the editor]. J Neurosurg Pediatr, 17(4), 380-381.
  2. Riva-Cambrin J, Kestle JR (2014). In reply [Letter to the editor]. Neurosurgery, 74(1), E153-4.

Abstract

  1. Maese L, Bruggers C, Putnam A, Kestle J, Moore K (06/01/2015). Extended bevacizumab and irinotecan therapy in pediatric pilomyxoid astrocytoma [Abstract]. Ped Blood & Cancer, 62, 83.
  2. Barkan H, Kestle J, Van Orman C, Filloux F, Sparrow S, Combe S, Hedlund G, Burr R, Johnson M, Orton K, Sweney M, Reilly M, Collier AM, Euler M, Funke M (02/12/2013). Validation of magnetoencephalography (MEG) as presurgical evaluation tool in pediatric patients with localization-related intractable epilepsy [Abstract]. Neurology, 80, PD4. 004.
  3. Yong RL, Habrock-Bach T, Vaughan M, Kestle JR, Steinbok P (06/01/2011). Symptomatic retethering of the spinal cord after section of a tight filum terminale [Abstract]. Neurosurgery, 68, 1594-1601.
  4. Simon TD, Whitlock K, Riva-Cambrin J, Kestle J, Rosenfeld M, Dean JM, Holubkov R, Langley M, Hamblett N (2010). Risk factors for CSF shunt infection in patients undergoing CSF shunt placement [Abstract]. Pediatric Academic Societies, 65, 4502.89.
  5. Kestle J, Van Orman C (2005). Surgery for localized epilepsy in children [Abstract]. Childs Nerv Syst, 21, 846.
  6. Basheer S, Connolly M, Sherman E, Hendson G, Kestle J, Steinbok P (2004). Hemispheric surgery for instractable epilepsy: outcome and complications [Abstract]. Can J Neurol Sci, 31, S1.
  7. Aldana PR, Kestle J, Brockmeyer DL, Walker ML (2002). Results of endoscopic septostomy in the treatment of isolated ventricular hydrocephalus [Abstract]. Childs Nerv Syst, 18, 547.
  8. Cochrane D, Kestle J (2002). Ventricular shunting for hydrocephalus in children: patients, procedures, surgeons and institutions [Abstract]. Can J Neurol Sci, 29, S20.
  9. Kestle J, Drake J, Cochrane D, Milner R for the ESIT participants (2001). The Endoscopic Shunt Insertion Trial: primary results.β [Abstract]. Neurosurgery, 49, 530.
  10. Kestle J (2001). Pediatric peri-insular hemispherotomy [Abstract]. Nervous System in Children (Journal of the Japanese Society for Pediatric Neurosurgery), 26, 297.
  11. Kestle J for the Strata Valve Study Group (2001). Clinical experience with the Strata valve [Abstract]. Nervous System in Children (Journal of the Japanese Society for Pediatric Neurosurgery), 26, 255.
  12. Kestle J (2001). Endoscopic shunt insertion trial [Abstract]. Nervous System in Children (Journa of the Japanese Society for Pediatric Neurosurgery), 26, 251.
  13. Kestle J, Drake J (2001). Axillary nerve injuries in children [Abstract]. Nervous System in Children (Journal of the Japanese Society for Pediatric Neurosurgery), 26, 246.

Poster

  1. Verma A, Zhou H, Chin S, Bruggers C, Kestle J, Khatua S (11/18/2010). EGFR as predictor of relapse and potential therapeutic target in recurrent disseminated myxopapillary ependymoma. Poster session presented at 2010 Society for NeuroOncology, Montreal.
  2. Whitehead W, Kestle J (2000). Can we shorten the duration of treatment for CSF shunt infections? Poster session presented at Congress of Neurological Surgeons, San Antonio, TX.

Global Impact

Global Impact

Education History

Type School Degree Country
Fellowship Hospital for Sick Children
Pediatric Neurosurgery
Fellow Canada
Fellowship The Toronto Hospital
Peripheral Nerve Surgery
Fellow Canada
Residency University of Toronto
Neurosurgery
Resident Canada
Graduate Training McMaster University
Biostatistics and Epidemiology
M.S. Canada
Internship St. Michael's Hospital
Surgery
Intern Canada
Professional Medical University of Western Ontario
M.D. Canada
Undergraduate University of Western Ontario
Biology
B.S. Canada

Selected Provider Publications

Journal Article

  1. Simon TD, Kronman MP, Whitlock KB, Gove N, Browd SR, Holubkov R, Kestle JR, Kulkarni AV, Langley M, Limbrick DD Jr, Luerssen TG, Oakes J, Riva-Cambrin J, Rozzelle C, Shannon C, Tamber M, Wellons JC 3rd, Whitehead WE, Mayer-Hamblett N (2016). Variability in Management of First Cerebrospinal Fluid Shunt Infection: A Prospective Multi-Institutional Observational Cohort Study.LID - S0022-3476(16)30877-0 [pii]LID - 10.1016/j.jpeds.2016.08.094 [doi]. (Epub ahead of print) J Pediatr.
    Global Impact: Global.

  2. Johns D, Anstadt E, Donato D, Kestle J, Riva-Cambrin J, Siddiqi F, Gociman B (2016). Early Posterior Vault Distraction Osteogenesis for the Treatment of Syndromic Craniosynostosis. Craniomaxillofac Trauma Reconstr, 9(3), 219-23.
    Global Impact: Global.

  3. Kulkarni AV, Riva-Cambrin J, Holubkov R, Browd SR, Cochrane DD, Drake JM, Limbrick DD, Rozzelle CJ, Simon TD, Tamber MS, Wellons JC 3rd, Whitehead WE, Kestle JR (2016). Endoscopic third ventriculostomy in children: prospective, multicenter results from the Hydrocephalus Clinical Research Network. J Neurosurg Pediatr, 1-7.
    Global Impact: Global.

  4. Ravindra VM, Bollo RJ, Sivakumar W, Akbari H, Naftel RP, Limbrick DD Jr, Jea A, Gannon S, Shannon C, Birkas Y, Yang GL, Prather CT, Kestle JR, Riva-Cambrin J (2016). Predicting Blunt Cerebrovascular Injury in Pediatric Trauma: Validation of the "Utah Score". (Epub ahead of print) J Neurotrauma.
    Global Impact: Global.

  5. Guan J, Brock AA, Karsy M, Couldwell WT, Schmidt MH, Kestle J, Jensen RL, Dailey AT, Schmidt RH (In press). Managing concurrent surgery: An analysis of 1053 neurosurgical and spine cases. J Neurosurg.
    Global Impact: Global.

  6. Kestle JR, Holubkov R, Douglas Cochrane D, Kulkarni AV, Limbrick DD Jr, Luerssen TG, Jerry Oakes W, Riva-Cambrin J, Rozzelle C, Simon TD, Walker ML, Wellons JC 3rd, Browd SR, Drake JM, Shannon CN, Tamber MS, Whitehead WE (2016). A new Hydrocephalus Clinical Research Network protocol to reduce cerebrospinal fluid shunt infection. J Neurosurg Pediatr, 17(4), 391-6.
    Global Impact: Global.

  7. Riva-Cambrin J, Kestle JR, Holubkov R, Butler J, Kulkarni AV, Drake J, Whitehead WE, Wellons JC 3rd, Shannon CN, Tamber MS, Limbrick DD Jr, Rozzelle C, Browd SR, Simon TD (2016). Risk factors for shunt malfunction in pediatric hydrocephalus: a multicenter prospective cohort study. J Neurosurg Pediatr, 17(4), 382-90.
    Global Impact: Global.

  8. Walicke P, Abosch A, Asher A, Barker FG II, Harbaugh R, Jehi L, Kestle J, Koroshetz W, Little R, Rubin D, Valadka A, Wisniewski S, Chiocca EA, for the Workshop Participants (In Press). Launching effectiveness research to guide practice in neurosurgery: outcomes from an NINDS workshop report. J Neurosurg.
    Global Impact: Global.

  9. Verma A, Zhou H, Chin S, Bruggers C, Kestle J, Khatua S (2012). EGFR as a predictor of relapse in myxopapillary ependymoma. Pediatr Blood Cancer, 59(4), 746-8.
    Global Impact: Global.

  10. Wellons JC 3rd, Holubkov R, Browd SR, Riva-Cambrin J, Whitehead W, Kestle J, Kulkarni AV (2013). The assessment of bulging fontanel and splitting of sutures in premature infants: an interrater reliability study by the Hydrocephalus Clinical Research Network. J Neurosurg Pediatr, 11(1), 12-4.
    Global Impact: Global.

  11. Al-Tamimi YZ, Sinha P, Chumas PD, Crimmins D, Drake J, Kestle J, Hayward R, Solanki GA, Thomson S, Thorne J (2014). Ventriculoperitoneal shunt 30-day failure rate: a retrospective international cohort study. Neurosurgery, 74(1), 29-34.
    Global Impact: Global.

  12. Steinbok P, Durity F, Kestle J, Cochrane DD (2015). Pediatric neurosurgery at British Columbia's Children's Hospital. Childs Nerv Syst, 31(9), 1419-27.
    Global Impact: Global.

  13. McAllister JP 2nd, Williams MA, Walker ML, Kestle JR, Relkin NR, Anderson AM, Gross PH, Browd SR (2015). An update on research priorities in hydrocephalus: overview of the third National Institutes of Health-sponsored symposium "Opportunities for Hydrocephalus Research: Pathways to Better Outcomes". J Neurosurg, 123(6), 1427-38.
    Global Impact: Global.

  14. Bowers C, Taussky P, Kestle JR, Park MS (2015). A Neurosurgical Call to Arms: Lessons from ARUBA, Mr. Clean, and the Hydrocephalus Clinical Research Network. World Neurosurg, 84(2), 202-4.
    Global Impact: Global.

  15. Johns D, Blagg R, Kestle JR, Riva-Cambrin JK, Siddiqi F, Gociman B (2015). Distraction Osteogenesis Technique for the Treatment of Nonsyndromic Sagittal Synostosis. Plast Reconstr Surg Glob Open, 3(7), e474.
    Global Impact: Global.

  16. Gopalakrishnan CV, Kestle JR, Connolly MB (2015). The "vagal ansa": a source of complication in vagus nerve stimulation. J Neurosurg Pediatr, 15(5), 535-8.
    Global Impact: Global.

  17. Spader HS, Hertzler DA, Kestle JR, Riva-Cambrin J (2015). Risk factors for infection and the effect of an institutional shunt protocol on the incidence of ventricular access device infections in preterm infants. J Neurosurg Pediatr, 15(2), 156-60.
    Global Impact: Global.

  18. Gociman B, Blagg R, Agko M, Goodwin I, Kestle JR, Siddiqi F (2014). The metopic angle: a novel assessment tool of the trigonocephalic frontal deformity and its correction. J Craniofac Surg, 25(6), 2101-4.
    Global Impact: Global.

  19. Kulkarni AV, Riva-Cambrin J, Browd SR, Drake JM, Holubkov R, Kestle JR, Limbrick DD, Rozzelle CJ, Simon TD, Tamber MS, Wellons JC 3rd, Whitehead WE (2014). Endoscopic third ventriculostomy and choroid plexus cauterization in infants with hydrocephalus: a retrospective Hydrocephalus Clinical Research Network study. J Neurosurg Pediatr, 14(3), 224-9.
    Global Impact: Global.

  20. Whitehead WE, Riva-Cambrin J, Wellons JC 3rd, Kulkarni AV, Browd S, Limbrick D, Rozzelle C, Tamber MS, Simon TD, Shannon CN, Holubkov R, Oakes WJ, Luerssen TG, Walker ML, Drake JM, Kestle JR (2014). Factors associated with ventricular catheter movement and inaccurate catheter location: post hoc analysis of the hydrocephalus clinical research network ultrasound-guided shunt placement study. J Neurosurg Pediatr, 14(2), 173-8.
    Global Impact: Global.

  21. Simon TD, Mayer-Hamblett N, Whitlock KB, Langley M, Kestle JR, Riva-Cambrin J, Rosenfeld M, Thorell EA (2014). Few Patient, Treatment, and Diagnostic or Microbiological Factors, Except Complications and Intermittent Negative Cerebrospinal Fluid (CSF) Cultures During First CSF Shunt Infection, Are Associated With Reinfection. J Pediatric Infect Dis Soc, 3(1), 15-22.
    Global Impact: Global.

  22. Simon TD, Butler J, Whitlock KB, Browd SR, Holubkov R, Kestle JR, Kulkarni AV, Langley M, Limbrick DD Jr, Mayer-Hamblett N, Tamber M, Wellons JC 3rd, Whitehead WE, Riva-Cambrin J (2014). Risk factors for first cerebrospinal fluid shunt infection: findings from a multi-center prospective cohort study. J Pediatr, 164(6), 1462-8.e2.
    Global Impact: Global.

  23. Simon TD, Whitlock KB, Riva-Cambrin J, Kestle JR, Rosenfeld M, Dean JM, Holubkov R, Langley M, Mayer-Hamblett N (2012). Association of intraventricular hemorrhage secondary to prematurity with cerebrospinal fluid shunt surgery in the first year following initial shunt placement. J Neurosurg Pediatr, 9(1), 54-63.
    Global Impact: Global.

  24. Brockmeyer DL, Ragel BT, Kestle JR (2012). The pediatric cervical spine instability study. A pilot study assessing the prognostic value of four imaging modalities in clearing the cervical spine for children with severe traumatic injuries. Childs Nerv Syst, 28(5), 699-705.
    Global Impact: Global.

  25. Simon TD, Whitlock KB, Riva-Cambrin J, Kestle JR, Rosenfeld M, Dean JM, Holubkov R, Langley M, Hamblett NM (2012). Revision surgeries are associated with significant increased risk of subsequent cerebrospinal fluid shunt infection. Pediatr Infect Dis J, 31(6), 551-6.
    Global Impact: Global.

  26. Riva-Cambrin J, Shannon CN, Holubkov R, Whitehead WE, Kulkarni AV, Drake J, Simon TD, Browd SR, Kestle JR, Wellons JC 3rd (2012). Center effect and other factors influencing temporization and shunting of cerebrospinal fluid in preterm infants with intraventricular hemorrhage. J Neurosurg Pediatr, 9(5), 473-81.
    Global Impact: Global.

  27. Gociman B, Marengo J, Ying J, Kestle JR, Siddiqi F (2012). Minimally invasive strip craniectomy for sagittal synostosis. J Craniofac Surg, 23(3), 825-8.
    Global Impact: Global.

  28. Cress M, Kestle JR, Holubkov R, Riva-Cambrin J (2013). Risk factors for pediatric arachnoid cyst rupture/hemorrhage: a case-control study. Neurosurgery, 72(5), 716-22; discussion 722.
    Global Impact: Global.

  29. Gociman B, Agko M, Blagg R, Garlick J, Kestle JR, Siddiqi F (2013). Endoscopic-assisted correction of metopic synostosis. J Craniofac Surg, 24(3), 763-8.
    Global Impact: Global.

  30. Kalra RR, Kestle JR (2013). An assessment of academic productivity in pediatric neurosurgery. J Neurosurg Pediatr, 12(3), 262-5.
    Global Impact: Global.

  31. Kulkarni AV, Riva-Cambrin J, Butler J, Browd SR, Drake JM, Holubkov R, Kestle JR, Limbrick DD, Simon TD, Tamber MS, Wellons JC 3rd, Whitehead WE (2013). Outcomes of CSF shunting in children: comparison of Hydrocephalus Clinical Research Network cohort with historical controls: clinical article. J Neurosurg Pediatr, 12(4), 334-8.
    Global Impact: Global.

  32. Whitehead WE, Riva-Cambrin J, Wellons JC 3rd, Kulkarni AV, Holubkov R, Illner A, Oakes WJ, Luerssen TG, Walker ML, Drake JM, Kestle JR (2013). No significant improvement in the rate of accurate ventricular catheter location using ultrasound-guided CSF shunt insertion: a prospective, controlled study by the Hydrocephalus Clinical Research Network. J Neurosurg Pediatr, 12(6), 565-74.
    Global Impact: Global.

  33. Gross P, Reed GT, Engelmann R, Kestle JR (2014). Hydrocephalus research funding from the National Institutes of Health: a 10-year perspective. J Neurosurg Pediatr, 13(2), 145-50.
    Global Impact: Global.

  34. Yong RL, Habrock-Bach T, Vaughan M, Kestle JR, Steinbok P (2011). Symptomatic retethering of the spinal cord after section of a tight filum terminale. Neurosurgery, 68(6), 1594-601; discussion 1601-2.
    Global Impact: Global.

  35. Khatua S, Moore KR, Vats TS, Kestle JR (2011). Diffuse intrinsic pontine glioma-current status and future strategies. Childs Nerv Syst, 27(9), 1391-7.
    Global Impact: Global.

  36. Kestle JR, Riva-Cambrin J, Wellons JC 3rd, Kulkarni AV, Whitehead WE, Walker ML, Oakes WJ, Drake JM, Luerssen TG, Simon TD, Holubkov R (2011). A standardized protocol to reduce cerebrospinal fluid shunt infection: the Hydrocephalus Clinical Research Network Quality Improvement Initiative. J Neurosurg Pediatr, 8(1), 22-9.
    Global Impact: Global.

  37. Kestle JR (2011). The less you look, the less you find. J Neurosurg, 115(5), 1038-9; author reply 1039.
    Global Impact: Global.

  38. Tuan TJ, Thorell EA, Hamblett NM, Kestle JR, Rosenfeld M, Simon TD (2011). Treatment and microbiology of repeated cerebrospinal fluid shunt infections in children. Pediatr Infect Dis J, 30(9), 731-5.
    Global Impact: Global.

  39. Hutchison JS, Frndova H, Lo TY, Guerguerian AM, Hypothermia Pediatric Head Injury Trial Investigators, Canadian Critical Care Trials Group Kestle JR (2011). Impact of hypotension and low cerebral perfusion pressure on outcomes in children treated with hypothermia therapy following severe traumatic brain injury: a post hoc analysis of the Hypothermia Pediatric Head Injury Trial. Dev Neurosci, 32(5-6), 406-412.
    Global Impact: Global.

  40. Adzick NS, Thom EA, Spong CY, Brock JW 3rd, Burrows PK, Johnson MP, Howell LJ, Farrell JA, Dabrowiak ME, Sutton LN, Gupta N, Tulipan NB, DAlton ME, Farmer DL, MOMS Investigators Kestle JR (2011). A randomized trial of prenatal versus postnatal repair of myelomeningocele. N Engl J Med, 364(11), 993-1004.
    Global Impact: Global.

  41. Brockmeyer DL, Ragel BT, Kestle J (2012). The Pediatric Cervical Spine Instability Study: a pilot study assessing the prognostic value of four imaging modalities in clearing the cervical spine for children with severe traumatic injuries. Childs Nerv Syst, 28(5), 699-705.
    Global Impact: Global.

  42. Kestle J, Townsend JJ, Brockmeyer DL, Walker ML (2004). Juvenile pilocytic astrocytoma of the brainstem in children. J Neurosurg, 101(1 Suppl), 1-6.
    Global Impact: Global.

  43. Kulkarni AV, Drake JM, Kestle JR, Mallucci CL, Sgouros S, Constantini S (2010). Endoscopic third ventriculostomy vs cerebrospinal fluid shunt in the treatment of hydrocephalus in children: a propensity score-adjusted analysis. Neurosurgery, 67(3), 588-93.
    Global Impact: Global.

  44. Simon TD, Hall M, Dean JM, Kestle JR, Riva-Cambrin J (2010). Reinfection following initial cerebrospinal fluid shunt infection. J Neurosurg Pediatr, 6(3), 277-85.
    Global Impact: Global.

  45. Kulkarni AV, Drake JM, Kestle JR, Mallucci CL, Sgouros S, Constantini S (2010). Predicting who will benefit from endoscopic third ventriculostomy compared with shunt insertion in childhood hydrocephalus using the ETV Success Score. J Neurosurg Pediatr, 6(4), 310-5.
    Global Impact: Global.

  46. Chen HH, Riva-Cambrin J, Brockmeyer D, Walker M, Kestle J (04/01/2011). Shunt failure due to intracranial migration of BioGlide® ventricular catheters. J Neurosurg Pediatr, 7(4), 408-412.
    Global Impact: Global.

  47. Wellons JC, Shannon CN, Kulkarni AV, Simon TD, Riva-Cambrin J, Whitehead WE, Oakes WJ, Drake JM, Luerssen TG, Walker ML, Kestle JR (2009). A multicenter retrospective comparison of conversion from temporary to permanent cerebrospinal fluid diversion in very low birth weight infants with posthemorrhagic hydrocephalus. J Neurosurg Pediatr, 4(1), 50-5.
    Global Impact: Global.

  48. Simon TD, Hall M, Riva-Cambrin J, Albert JE, Jeffries HE, Lafleur B, Dean JM, Kestle JR (2009). Infection rates following initial cerebrospinal fluid shunt placement across pediatric hospitals in the United States. Clinical article. J Neurosurg Pediatr, 4(2), 156-65.
    Global Impact: Global.

  49. La Barge DV 3rd, Ng PP, Stevens EA, Friedline NK, Kestle JR, Schmidt RH (2009). Extended intracranial applications for ethylene vinyl alcohol copolymer (Onyx): mycotic and dissecting aneurysms. Technical note. J Neurosurg, 111(1), 114-8.
    Global Impact: Global.

  50. Vachhrajani S, Kulkarni AV, Kestle JR (2009). Clinical practice guidelines. J Neurosurg Pediatr, 3(4), 249-56.
    Global Impact: Global.

  51. Drake J, Kulkarni A, Kestle J (2009). Endoscopic third ventriculostomy versus ventriculoperitoneal shunt in pediatric patients: a decision analysis. Childs Nerv Syst, 25, 467-472.
    Global Impact: Global.

  52. Kestle J (2008). Ventriculoperitoneal shunt in children: indications, equipment and techniques. Pan Arab Journal of Neurosurgery, 12(2), Supplement Ap.
    Global Impact: Global.

  53. Simon TD, Riva-Cambrin J, Srivastava R, Bratton SL, Dean JM, Kestle JR (2008). Hospital care for children with hydrocephalus in the United States: utilization, charges, comorbidities, and deaths. J Neurosurg Pediatr, 1(2), 131-7.
    Global Impact: Global.

  54. Williams MA, McAllister JP, Walker ML, Kranz DA, Bergsneider M, Del Bigio MR, Fleming L, Frim DM, Gwinn K, Kestle JR, Luciano MG, Madsen JR, Oster-Granite ML, Spinella G (2007). Priorities for hydrocephalus research: report from a National Institutes of Health-sponsored workshop. J Neurosurg, 107(5 Suppl), 345-57.
    Global Impact: Global.

  55. Kan P, Gooch J, Ploeger D, Grams B, Oberg W, Simonsen S, Walker ML, Kestle JRW (2008). Surgical treatment of spasticity in children: comparison of selective dorsal rhizotomy and intrathecal baclofen pump implantation. Childs Nerv Syst, 24, 239-243.
    Global Impact: Global.

  56. Klimo P Jr, Thompson CJ, Kestle JR, Schmidt MH (2005). A meta-analysis of surgery versus conventional radiotherapy for the treatment of metastatic spinal epidural disease. Neuro-Oncol, 7(1), 64-76.
    Global Impact: Global.

  57. Klimo P Jr, Thompson CJ, Drake J, Kestle JR (2004). Assessing the validity of the endoscopic shunt insertion trial: did surgical experience affect the results? J Neurosurg, 101(2 Suppl), 130-3.
    Global Impact: Global.

  58. Kestle JR, Walker ML (2005). A multicenter prospective cohort study of the Strata valve for the management of hydrocephalus in pediatric patients. J Neurosurg, 102(2 Suppl), 141-5.
    Global Impact: Global.

  59. Anderson RC, Kan P, Klimo P, Brockmeyer DL, Walker ML, Kestle JR (2004). Complications of intracranial pressure monitoring in children with head trauma. J Neurosurg, 101(1 Suppl), 53-8.
    Global Impact: Global.

  60. Klimo P Jr, Kestle JR (2005). Potentially useful outcome measures for clinical research in pediatric neurosurgery. J Neurosurg, 103(3 Suppl), 207-12.
    Global Impact: Global.

  61. Kestle JR, Cochrane DD, Drake JM (2006). Shunt insertion in the summer: is it safe? J Neurosurg, 105(3 Suppl), 165-8.
    Global Impact: Global.

  62. Kestle JR, Garton HJ, Whitehead WE, Drake JM, Kulkarni AV, Cochrane DD, Muszynski C, Walker ML (2006). Management of shunt infections: a multicenter pilot study. J Neurosurg, 105(3 Suppl), 177-81.
    Global Impact: Global.

  63. Kan P, Amini A, Hansen K, White GL Jr, Brockmeyer DL, Walker ML, Kestle JR (2006). Outcomes after decompressive craniectomy for severe traumatic brain injury in children. J Neurosurg, 105(5 Suppl), 337-42.
    Global Impact: Global.

  64. Kan P, Walker ML, Drake JM, Kestle JR (2007). Predicting slitlike ventricles in children on the basis of baseline characteristics at the time of shunt insertion. J Neurosurg, 106(5 Suppl), 347-9.
    Global Impact: Global.

  65. Kan P, Simonsen SE, Lyon JL, Kestle JR (2008). Cellular phone use and brain tumor: a meta-analysis. J Neurooncol, 86(1), 71-8.
    Global Impact: Global.

  66. Binning M, Ragel B, Brockmeyer DL, Walker ML, Kestle JR (2007). Evaluation of the necessity of postoperative imaging after craniosynostosis surgery. J Neurosurg, 107(1 Suppl), 43-5.
    Global Impact: Global.

  67. Kan P, Van Orman C, Kestle JR (2008). Outcomes after surgery for focal epilepsy in children. Childs Nerv Syst, 24(5), 587-91.
    Global Impact: Global.

  68. Kestle JRW, Cochrane DD, Drake JM (2006). Response to editorial: summer shunting. J Neurosurg, 105, 163-164.
    Global Impact: Global.

  69. Kan P, Kestle J (2007). Lack of efficacy of antibiotic impregnated shunt systems in preventing shunt infections in children. Childs Nerv Syst, 23, 773-777.
    Global Impact: Global.

  70. Kan P, Liu J, HedlundG, Brockmeyer D, Walker M, Kestle J (2006). The role of diffusion weighted MR imaging in pediatric brain tumors. Childs Nerv Syst, 22(11), 1435-1439.
    Global Impact: Global.

  71. McCall T, Rao G, Kestle J (2006). Work hour restrictions: Impact on neurosurgical resident training at the University of Utah. AANS Bulletin, 14(4), 17-22.
    Global Impact: Global.

  72. Kestle J (2003). Tracking resident work hours. AANS Bulletin, 12, 49.
    Global Impact: Global.

  73. Fassett D, Pingree J, Kestle J (2005). High incidence of tumor dissemination in myxopapillary ependymoma in children. J Neurosurg Pediatr, 102, 59-64.
    Global Impact: Global.

  74. Whitehead WE, Kestle JR (2001). The treatment of cerebrospinal fluid shunt infections. Results from a practice survey of the American Society of Pediatric Neurosurgeons. Pediatr Neurosurg, 35(4), 205-10.
    Global Impact: Global.

  75. Arthur AS, Whitehead WE, Kestle JR (2002). Duration of antibiotic therapy for the treatment of shunt infection: a surgeon and patient survey. Pediatr Neurosurg, 36(5), 256-9.
    Global Impact: Global.

  76. Hader WJ, Drake J, Cochrane D, Sparrow O, Johnson ES, Kestle J (2002). Death after late failure of third ventriculostomy in children. Report of three cases. J Neurosurg, 97(1), 211-5.
    Global Impact: Global.

  77. Garton HJ, Kestle JR, Cochrane DD, Steinbok P (2002). A cost-effectiveness analysis of endoscopic third ventriculostomy. Neurosurgery, 51(1), 69-77; discussion 77-8.
    Global Impact: Global.

  78. Hentschel S, Steinbok P, Cochrane DD, Kestle J (2002). Reduction of transfusion rates in the surgical correction of sagittal synostosis. J Neurosurg, 97(3), 503-9.
    Global Impact: Global.

  79. Cochrane DD, Kestle J (2002). Ventricular shunting for hydrocephalus in children: patients, procedures, surgeons and institutions in English Canada, 1989-2001. Eur J Pediatr Surg, 12 Suppl 1, S6-11.
    Global Impact: Global.

  80. Kestle JR, Drake JM, Cochrane DD, Milner R, Walker ML, Abbott R 3rd, Boop FA (2003). Lack of benefit of endoscopic ventriculoperitoneal shunt insertion: a multicenter randomized trial. J Neurosurg, 98(2), 284-90.
    Global Impact: Global.

  81. Aldana PR, Kestle JR, Brockmeyer DL, Walker ML (2003). Results of endoscopic septal fenestration in the treatment of isolated ventricular hydrocephalus. Pediatr Neurosurg, 38(6), 286-94.
    Global Impact: Global.

  82. Cochrane DD, Kestle JR (2003). The influence of surgical operative experience on the duration of first ventriculoperitoneal shunt function and infection. Pediatr Neurosurg, 38(6), 295-301.
    Global Impact: Global.

  83. Liu JK, Tenner MS, Gottfried ON, Stevens EA, Rosenow JM, Madan N, MacDonald JD, Kestle JR, Couldwell WT (2004). Efficacy of multiple intraarterial papaverine infusions for improvement in cerebral circulation time in patients with recurrent cerebral vasospasm. J Neurosurg, 100(3), 414-21.
    Global Impact: Global.

  84. Klimo P Jr, Kestle JR, MacDonald JD, Schmidt RH (2004). Marked reduction of cerebral vasospasm with lumbar drainage of cerebrospinal fluid after subarachnoid hemorrhage. J Neurosurg, 100(2), 215-24.
    Global Impact: Global.

  85. Klimo P Jr, Kestle JR, Schmidt MH (2003). Treatment of metastatic spinal epidural disease: a review of the literature. Neurosurg Focus, 15(5), E1.
    Global Impact: Global.

  86. Tyagi A, Drake J, Midha R, Kestle J (2000). Axillary nerve injuries in children. Pediatr Neurosurg, 32(5), 226-9.
    Global Impact: Global.

  87. Garton HJ, Kestle JR, Drake JM (2001). Predicting shunt failure on the basis of clinical symptoms and signs in children. J Neurosurg, 94(2), 202-10.
    Global Impact: Global.

  88. Kestle J, Cochrane D, Alisharan R (2000). The initial treatment of hydrocephalus: an assessment of surgeons' preference between third ventriculostomy and shunt insertion. Neurol Res, 22(1), 65-8.
    Global Impact: Global.

Review

  1. Ravindra VM, Kraus KL, Riva-Cambrin JK, Kestle JR (2015). The Need for Cost-Effective Neurosurgical Innovation-A Global Surgery Initiative. [Review]. World Neurosurgery, 84(5), 1458-61.
    Global Impact: Global.

  2. Drake J, Chumas P, Kestle J, Pierre-Kahn A, Vinchon M, Brown J, Pollack IF, Arai H (2006). Late rapid deterioration after endoscopic third ventriculostomy: additional cases and review of the literature. [Review]. Journal of Neurosurgery, 105(2 Suppl), 118-26.
    Global Impact: Global.

  3. Liu JK, Cole CD, Kestle JR, Brockmeyer DL, Walker ML (2005). Cranial base strategies for resection of craniopharyngioma in children. [Review]. Neurosurgical Focus, 18(6A), E9.
    Global Impact: Global.

  4. Browd SR, Ragel BT, Gottfried ON, Kestle JR (2006). Failure of cerebrospinal fluid shunts: part I: Obstruction and mechanical failure. [Review]. Pediatric Neurology, 34(2), 83-92.
    Global Impact: Global.

  5. Browd SR, Gottfried ON, Ragel BT, Kestle JR (2006). Failure of cerebrospinal fluid shunts: part II: overdrainage, loculation, and abdominal complications. [Review]. Pediatric Neurology, 34(3), 171-6.
    Global Impact: Global.

  6. Kan P, Kestle JR (2007). Designing randomized clinical trials in pediatric neurosurgery. [Review]. Child's Nervous System, 23(4), 385-90.
    Global Impact: Global.

  7. Binning MJ, Liu JK, Kestle JR, Brockmeyer DL, Walker ML (2007). Optic pathway gliomas: a review. [Review]. Neurosurgical Focus, 23(5), E2.
    Global Impact: Global.

  8. Klimo P, Kestle J, Schmidt M (2004). Clinical trials and evidence based medicine for metastatic spine disease. [Review]. Neurosurgery Clinics of North America, 15(4), 549-564.
    Global Impact: Global.

  9. Kestle JR (2003). Pediatric hydrocephalus: current management. [Review]. Neurologic Clinics, 21(4), 883-95, vii.
    Global Impact: Global.

  10. Drake JM, Kestle JR, Tuli S (2000). CSF shunts 50 years on--past, present and future. [Review]. Child's Nervous System, 16(10-11), 800-4.
    Global Impact: Global.

  11. Drake JM, Kestle JR, Tuli S (2000). Cerebrospinal fluid shunt technology. [Review]. Clinical Neurosurgery, 47, 336-45.
    Global Impact: Global.

Book Chapter

  1. Ravindra VM, Sivakumar W, Riva-Cambrin JK, Kestle JR (In Press). Clinical management guidelines: pros and cons. In Good Paper, Successful Career: Guidelines for Biomedical Students, Residents and Researchers.
    Global Impact: Global.

  2. Ravindra VM, Sivakumar W, Riva-Cambrin JK, Kestle JR (In Press). Clinical management guidelines: definition and development. In Good Paper, Successful Career: Guidelines for Biomedical Students, Residents and Researchers.
    Global Impact: Global.

  3. Kestle JR (In Press). Hydrocephalus in children: etiology and overall management. In Winn H (Ed.), Youman's Neurological Surgery (7th ed.). Philadelphia: Elsevier.
    Global Impact: Global.

  4. Sivakumar W, Ravindra VM, Riva-Cambrin J, Kestle JR (2015). Ventricular shunting for hydrocephalus. In Cohen A (Ed.), Pediatric Neurosurgery: Tricks of the Trade (pp. 316-). New York: Thieme.
    Global Impact: Global.

  5. Garber S, Kestle JRW (2014). Brain stem tumors. In Berger M, Bernstein M (Eds.), Neuro-Oncology: The Essentials (3rd ed, Chapter 27). New York: Thieme.
    Global Impact: Global.

  6. Kalra RS, Kestle J (2014). Treatment of hydrocephalus with shunts. In Albright A, Pollack I, Adelson D (Eds.), Principles and Practice of Pediatric Neurosurgery (3rd). New York: Thieme Medical Publishers.
    Global Impact: Global.

  7. Kestle JR (2011). Hydrocephalus in children: Approach to the patient. In H.R. Winn (Ed.), Youman's Neurological Surgery (6th ed.). Philadelphia: Elsevier.
    Global Impact: Global.

  8. Kan P, Kestle JRW (2008). Brainstem tumors. In Berger M and Bernstein M (Eds.), Neuro-Oncology: The Essentials (2nd ed, Chapter 26, pp. 277-286). New York: Thieme.
    Global Impact: Global.

  9. Kestle JR (2009). Clinical trials in hydrocephalus: What have we learned? In Malucci C, Sgouros S, Abbott IR (Eds.), Cerebrospinal Fluid Disorders (Chapter 26, pp. 488-493). New York: Informa Healthcare.
    Global Impact: Global.

  10. Kestle J (2010). Tumors of the cranial vault in children. In Tonn J, Westphal M, Rutka J (Eds.), Oncology of CNS Tumors (2nd ed, Chapter 48, pp. 629-635). Berlin Heidelberg: Springer-Verlag.
    Global Impact: Global.

  11. Wetjen N, Kestle J (2010). Peri-insular hemispherotomy. In Cateltepe O, Jallo G (Eds.), Pediatric Epilepsy Surgery: Preoperative Assessment and Surgical Treatment (Chapter 28, pp. 251-259). New York: Thieme Medical Publishers.
    Global Impact: Global.

  12. Anderson R, Garton H, Kestle JRW (2007). Treatment of hydrocephalus with shunts. In Albright A, Pollack I, Adelson D (Eds.), Principles and Practices in Pediatric Neurosurgery (2nd). New York: Thieme Medical Publishers.
    Global Impact: Global.

  13. Browd S, Kestle J (2006). Peri-insular hemispherotomy. In Silbergeld D and Miller J (Eds.), Epilepsy Surgery: Principles and Controversies (pp. 585-588). Taylor and Francis Books.
    Global Impact: Global.

  14. Rao G, Kestle J (2006). Calvarial tumors in children. In Tonn J, Westphal M, Grossman S, Rutka J (Eds.), Neuro-Oncology of CNS Tumors. Springer.
    Global Impact: Global.

  15. Rao G, Kestle J (2005). Pleomorphic xanthoastrocytoma. In Berger M; Prados M (Ed.), Textbook of Neuro-Oncology. Philadelphia: Elsevier Saunders.
    Global Impact: Global.

  16. Kestle J, Drake J (2004). Patterns of shunt failure according to the hydrodynamic features of the valve: Lessons from the Shunt Design Trial. In Cinalli G; Maixner W; Sainte-Rose C (Ed.), Pediatric Hydrocephalus. Milano: Springer-Verlag.
    Global Impact: Global.

  17. Kestle J (2003). Communicating hydrocephalus. In Batjer H; Loftus C (Ed.), Textbook of Neurological Surgery. Philadelphia: Lippincott Williams & Wilkins.
    Global Impact: Global.

  18. Kestle J (2001). Design of clinical trials. In McLone D; et al (Ed.), Pediatric Neurosurgery: Surgery of the Developing Nervous System. Philadelphia: W. B. Saunders.
    Global Impact: Global.

Conference Proceedings

  1. Tamber M, Kulkarn A, Browd S, Shannon C, Rozzelle C, Cochrane D, Drake J, Riva-Cambrin J, Oakes WJ, Kestle J, Wellons J, Limbrick D, Holubkov R, Naftel R, Simon T, Luerssen T, Whitehead W (05/04/2016). Hydrocephalus Clinical Research Network (HCRN) Shunt Infection Protocol Implementation Across Pediatric Neurosurgery – A Cross-Sectional Survey. American Association of Neurological Surgeons/Congress of Neurological Surgeons Section on Pediatric Neurological Surgery, Chicago, IL.
    Global Impact: Global.

  2. Simon TD, Kronman M, Whitlock K, Gove N, Browd S, Holubkov R, Kestle J, Kulkarni A, Langley M, Limbrick M, Luerssen T, Oakes J, Riva-Cambrin J, Rozzelle C, Shannon C, Tamber M, Wellons J, Whitehead W, Mayer-Hamblett N (05/01/2016). Adherence to guidelines in treatment for first cerebrospinal fluid (CSF) shunt infection. Pediatric Academic Society, 70, 2165-2168.
    Global Impact: Global.

  3. Simon TD, Kronman M, Gove N, Whitlock K, Browd S, Holubkov R, Kestle J, Kulkarni A, Langley M, Limbrick D, Luerssen T, Oakes J, Riva-Cambrin J, Rozzelle C, Shannon C, Tamber M, Wellons J, Whitehead W, Hamblett N (05/03/2016). Surgical apparoch to treatment of first cerebrospinal fluid (CSF) shunt infection is associated with reinfection. Pediatric Academic Society, EPAS, 70, 4450-4457.
    Global Impact: Global.

Case Report

  1. Rocque BG, George TM, Kestle J, Iskandar BJ (2011). Treatment practices for Chiari malformation type I with syringomyelia: results of a survey of the American Society of Pediatric Neurosurgeons. J Neurosurg Pediatr, 8(5), 430-7.
    Global Impact: Global.

  2. Anderson RC, Walker ML, Viner JM, Kestle JR (2004). Adjustment and malfunction of a programmable valve after exposure to toy magnets. Case report. J Neurosurg, 101(2 Suppl), 222-5.
    Global Impact: Global.

  3. Fassett DR, Pingree J, Kestle JR (2005). The high incidence of tumor dissemination in myxopapillary ependymoma in pediatric patients. Report of five cases and review of the literature. J Neurosurg, 102(1 Suppl), 59-64.
    Global Impact: Global.

  4. Liu JK, Cole CD, Sherr GT, Kestle JR, Walker ML (2005). Noncommunicating spinal extradural arachnoid cyst causing spinal cord compression in a child. J Neurosurg, 103(3 Suppl), 266-9.
    Global Impact: Global.

  5. McCall TD, Liu JK, Kestle JR (2006). Sporadic osteochondroma of the cervical spine. Case illustration. J Neurosurg, 104(4 Suppl), 293.
    Global Impact: Global.

  6. Binning MJ, Ragel BT, Walker ML, Kestle JR (2006). Retained peritoneal shunt tubing causing hematuria. Case illustration. J Neurosurg, 104(6 Suppl), 434.
    Global Impact: Global.

  7. Amini A, Liu JK, Kestle JR (2006). Disseminated medulloblastoma. J Neurooncol, 80(2), 157-8.
    Global Impact: Global.

  8. Gluf WM, Kestle JR (2002). 'Cortical thumb sign' in X-linked hydrocephalus. Pediatr Neurosurg, 37(2), 107-8.
    Global Impact: Global.

Editorial

  1. Kestle JR (2016). Editorial: The learning curve in surgical randomized controlled trials. J Neurosurg Pediatr, 18(2), 145.
    Global Impact: Global.

  2. Kestle JRW (2016). Editorial: The challenges of determining natural history. J Neurosurg Pediatr, 17(2), 121-122.
    Global Impact: Global.

  3. Kestle JR (2015). Editorial: Measuring resident operative skills. J Neurosurg Pediatr, 1-2.
    Global Impact: Global.

  4. Kestle JR (2015). Editorial: Bed rest after filum surgery. J Neurosurg Pediatr, 15(5), 459; discussion 460.
    Global Impact: Global.

  5. Kestle JR (2015). Editorial: Food and Drug Administration Safety Communication on rhBMP-2 use. J Neurosurg Pediatr, 16(1), 1-3.
    Global Impact: Global.

  6. Kestle JR (2015). Editorial: industry-sponsored research. J Neurosurg, 122(1), 136-8.
    Global Impact: Global.

  7. Kestle JR (2015). Administrative database research. J Neurosurg, 122(2), 441-2.
    Global Impact: Global.

  8. Kestle JRW (2014). Counterpoint: Shunts Are Not Going Away So We Need to Do Them Well. AANS Neurosurgeon, 23(1).
    Global Impact: Global.

  9. Kestle JR (2012). Editorial: intraventricular hemorrhage and posthemorrhagic hydrocephalus. J Neurosurg Pediatr, 9(3), 239-40; discussion 240-1.
    Global Impact: Global.

  10. Kestle JR (2012). Retethering after filum cutting. World Neurosurg, 77(1), 82.
    Global Impact: Global.

  11. Kestle JR (2012). Abdominal binders. J Neurosurg Pediatr, 9(6), 613; discussion 614.
    Global Impact: Global.

  12. Kestle JR (2013). Shunt insertion. J Neurosurg, 119(1), 64.
    Global Impact: Global.

  13. Kestle J (2011). The less you look, the less you find. J Neurosurg, 115(5), 1038-1039.
    Global Impact: Global.

  14. Kestle JR (2011). Pooling data on antibiotic-impregnated shunts. J Neurosurg Pediatr, 8(3), 257-8; discussion 258.
    Global Impact: Global.

  15. Kestle JR (2010). Antibiotic-impregnated external ventricular drains. J Neurosurg, 113(1), 85; discussion 85.
    Global Impact: Global.

  16. Kestle JR (2010). Shunt malfunction. J Neurosurg, 113(6), 1270-1; discussion 1271-2.
    Global Impact: Global.

  17. Kestle JR (2008). It's randomized and double blinded... what more do we want? J Neurosurg Pediatr, 2(2), 109; discussion 110.
    Global Impact: Global.

Letter

  1. Riva-Cambrin J, Kestle JRW, Simon TD, The Hydrocephalus Clinical Research Network (2016). Author's response to editorial [Letter to the editor]. J Neurosurg Pediatr, 17(4), 380-381.
    Global Impact: Global.

  2. Riva-Cambrin J, Kestle JR (2014). In reply [Letter to the editor]. Neurosurgery, 74(1), E153-4.
    Global Impact: Global.

Abstract

  1. Maese L, Bruggers C, Putnam A, Kestle J, Moore K (06/01/2015). Extended bevacizumab and irinotecan therapy in pediatric pilomyxoid astrocytoma [Abstract]. Ped Blood & Cancer, 62, 83.
    Global Impact: Global.

  2. Barkan H, Kestle J, Van Orman C, Filloux F, Sparrow S, Combe S, Hedlund G, Burr R, Johnson M, Orton K, Sweney M, Reilly M, Collier AM, Euler M, Funke M (02/12/2013). Validation of magnetoencephalography (MEG) as presurgical evaluation tool in pediatric patients with localization-related intractable epilepsy [Abstract]. Neurology, 80, PD4. 004.
    Global Impact: Global.

  3. Simon TD, Whitlock K, Riva-Cambrin J, Kestle J, Rosenfeld M, Dean JM, Holubkov R, Langley M, Hamblett N (2010). Risk factors for CSF shunt infection in patients undergoing CSF shunt placement [Abstract]. Pediatric Academic Societies, 65, 4502.89.
    Global Impact: Global.

  4. Yong RL, Habrock-Bach T, Vaughan M, Kestle JR, Steinbok P (06/01/2011). Symptomatic retethering of the spinal cord after section of a tight filum terminale [Abstract]. Neurosurgery, 68, 1594-1601.
    Global Impact: Global.

  5. Kestle J, Van Orman C (2005). Surgery for localized epilepsy in children [Abstract]. Childs Nerv Syst, 21, 846.
    Global Impact: Global.

  6. Basheer S, Connolly M, Sherman E, Hendson G, Kestle J, Steinbok P (2004). Hemispheric surgery for instractable epilepsy: outcome and complications [Abstract]. Can J Neurol Sci, 31, S1.
    Global Impact: Global.

  7. Aldana PR, Kestle J, Brockmeyer DL, Walker ML (2002). Results of endoscopic septostomy in the treatment of isolated ventricular hydrocephalus [Abstract]. Childs Nerv Syst, 18, 547.
    Global Impact: Global.

  8. Cochrane D, Kestle J (2002). Ventricular shunting for hydrocephalus in children: patients, procedures, surgeons and institutions [Abstract]. Can J Neurol Sci, 29, S20.
    Global Impact: Global.

  9. Kestle J, Drake J, Cochrane D, Milner R for the ESIT participants (2001). The Endoscopic Shunt Insertion Trial: primary results.β [Abstract]. Neurosurgery, 49, 530.
    Global Impact: Global.

  10. Kestle J (2001). Pediatric peri-insular hemispherotomy [Abstract]. Nervous System in Children (Journal of the Japanese Society for Pediatric Neurosurgery), 26, 297.
    Global Impact: Global.

  11. Kestle J for the Strata Valve Study Group (2001). Clinical experience with the Strata valve [Abstract]. Nervous System in Children (Journal of the Japanese Society for Pediatric Neurosurgery), 26, 255.
    Global Impact: Global.

  12. Kestle J (2001). Endoscopic shunt insertion trial [Abstract]. Nervous System in Children (Journa of the Japanese Society for Pediatric Neurosurgery), 26, 251.
    Global Impact: Global.

  13. Kestle J, Drake J (2001). Axillary nerve injuries in children [Abstract]. Nervous System in Children (Journal of the Japanese Society for Pediatric Neurosurgery), 26, 246.
    Global Impact: Global.

Poster

  1. Verma A, Zhou H, Chin S, Bruggers C, Kestle J, Khatua S (11/18/2010). EGFR as predictor of relapse and potential therapeutic target in recurrent disseminated myxopapillary ependymoma. Poster session presented at 2010 Society for NeuroOncology, Montreal.
    Global Impact: Global.

  2. Whitehead W, Kestle J (2000). Can we shorten the duration of treatment for CSF shunt infections? Poster session presented at Congress of Neurological Surgeons, San Antonio, TX.
    Global Impact: Global.

Career

Institution Description Country
University of British Columbia Professor and Head, Department of Surgery Canada
University of British Columbia Head, Section of Clinical Epidemiology, Department of Surgery Canada
British Columbia's Children's Hospital Pediatric Neurosurgeon Canada
University of British Columbia Associate Member, Department of Health Care and Epidemiology Canada
University of British Columbia Assistant Professor Canada

Clinical Trials

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