- Amyotrophic Lateral Sclerosis
- Neural Stem Cells
- Translational Research
- Parkinson Disease
- RNA, Antisense
- Epidemiologic Factors
- Genomic and Personalized Medicine
- Animal Model Development
- Spinocerebellar Ataxias
Board Certification and Academic Information
||Neurology - Professor
||American Board of Psychiatry & Neurology (Neurology)
Academic Office Locations
|Academic Office Phone Number
||Academic Office Address
||Clinical Neurosciences Center
Department of Neurology
175 North Medical Drive East
Salt Lake City, UT 84132
Dr. Stefan Pulst is Professor and Chair of the Department of Neurology at the University of Utah in Salt Lake City. He received his neurological training at the Medizinische Hochschule Hannover in Germany and in the Longwood Program at Harvard Medical School in Boston. He then joined Dr. Dennis Deen at the UCSF Brain Tumor Research Center to study in vitro cytotoxicity models and subsequently did a postdoctoral fellowship in neurobiology at UCSF, where he worked with Dr. Earl Mayeri on peptidergic neurotransmission in Aplysia. Prior to moving to the University of Utah in 2007, he was the Carmen and Louis Warschaw Chair in Neurology at Cedars-Sinai Medical Center in Los Angeles and Professor of Medicine, Neurology, and Neurobiology at the UCLA School of Medicine.
Research in the Pulst laboratory focuses on inherited diseases of the nervous system with an emphasis on spinocerebellar ataxias and Parkinson disease. His group identified the genes for SCA2 and SCA13, and as part of collaborative groups, the genes for SCA10 and Neurofibromatosis 2. Scientists in the laboratory are using transgenic and knockout mouse models to understand the molecular and cellular causes of these diseases and to develop novel therapies. Another interest relates to tumor suppressor genes controlling proliferation of Schwann cells. Recently, research in the group has branched out into understanding the genetic structure of human attention and the genetic epidemiology of Parkinson disease and degenerative ataxias in the state of Utah using the unique resources of the Utah Population Database.
Dr. Pulst has served on peer-review groups for the NIH and various international research agencies and was chair of the NIH Genetics of Health and Disease study section. He was the founding chair of the Section on Neurogenetics and the Basic Science Subcommittee of the American Academy of Neurology. He was a member of the AAN Science Committee and served as Chair from 2006 to 2011. He is now a member of the AAN Board of Directors.
Dr. Pulst served on the editorial board of Continuum, was past editor-in-chief of the international journal Current Genomics, and currently serves on the editorial boards of Nature Reviews Neurology, Journal of Molecular Neuroscience, Cerebellum, Neurogenetics, and Experimental Neurology. He has edited three books on Neurogenetics, the Genetics of Movement disorders, and most recently on the ataxias and spastic paraplegias.
Work in his laboratory is supported by grants from the National Institutes of Health, a project grant as part of the UCLA Udall Parkinson Disease Center and the US Army Neurofibromatosis research program. He has enjoyed mentoring scientists and neurologists on a number of KO8, K23, and other mentored awards.