Metabolism Intersections in Cancer Cell Biology Mini Symposium

This mini symposium highlights the integration of metabolic and oncogenic signaling. Cancer cells co-opt metabolic routes to drive energy production, cell growth, division, and invasion in different environments. Common themes, like how metabolic pathways integrate mechanical signals from the environment to influence cell behavior, will be covered. This includes integration with the mitogenic EGFR/RAS/ERK-MAPK pathway and mechanisms of therapeutic resistance. Trainee talks will highlight the contributions to the field by Huntsman Cancer Institute’s Cell Response and Regulation Program.

Questions? Contact Kat Haymond.

Date

September 5,2023
9 am–12:05 pm

Location

Huntsman Cancer Institute
Research South
First-floor Auditorium

Agenda

9:00–9:05 am	Introductions
9:05–9:40 am	Cynthia Reinhart-King Senior associate dean for research, distinguished professor of biomedical engineering and cell and developmental biology, Vanderbilt University Topic: The Intersection of Migration and Metabolism: Fueling the invasion of metastatic cells
9:40–10:15 am	Bruce Edgar, PhD Professor of oncological sciences and adjunct professor of human genetics, University of Utah Topic: EGFR signaling activates intestinal stem cells by promoting mitochondrial biogenesis and β-oxidation
10:15-10:25 am	Samantha Stam Michelle Mendoza Lab Topic: Metabolic changes induced by nutrient availability alters the protrusive state of migrating cells
10:25-10:35 am	Phaedra Ghazi Martin McMahon Lab Topic: Combined inhibition of ULK-mediated autophagy and KRASG12C controls tumor growth in preclinical models of lung cancer
10:35–10:50 am	Light refreshment break
10:50–11:25 am	Jessie Yanxiang Guo, PhD Associate professor in the division of medical oncology, department of medicine at the Robert Wood Johnson Medical School, Rutgers Cancer Institute of New Jersey Topic: The role of autophagy in KRAS-driven lung cancer
11:25–11:45 am	Alex Bott Jared Rutter Lab Topic: Transcriptional regulation of glycolysis
11:45 am–12:05 pm	Meghan Curtin Keren Hilgendorf Lab Topic: Lean adipocytes potently inhibit breast cancer growth through lipid signaling

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