COVID-19 Treatments & Preventive Therapy Available for High-Risk Individuals

Treatments are available to help prevent the development of severe symptoms in people who are at high risk for being hospitalized or dying from COVID-19. Treatments include:

There is also preventive therapy for high-risk individuals before they've been infected with or exposed to COVID-19. Treatments and preventive therapy for COVID-19 should not be used in place of COVID-19 vaccines, which are the best protection against the virus. 

INFORMACIÓN EN ESPAÑOL

Monoclonal Antibody Treatment: Bebtelovimab

Monoclonal antibodies are laboratory-made proteins that mimic the body’s immune system to fight off COVID-19 infection. Bebtelovimab is given by intravenous (IV) injection in an outpatient setting. A syringe will inject the medicine through a soft, flexible tube placed inside a vein in your hand or arm to deliver a one-time dose of the drug within 30 seconds. You will be observed by your health care provider for at least one hour after you receive the injection.

Eligibility Criteria

To qualify for monoclonal antibodies, you must meet all of the following criteria.

  • You test positive for SARS-CoV-2 (virus that causes COVID-19).
  • You currently have COVID-19 symptoms that began within the last seven days.
  • You are not newly on oxygen or on an increased oxygen supply.
  • You are not hospitalized.
  • You are at high risk for severe illness from COVID-19 due to your age and certain medical conditions, including being severely immunocompromised.

Pregnant people who are not vaccinated and have high-risk conditions may also qualify for monoclonal antibody treatment.

Antiviral Pill: Paxlovid

This antiviral pill stops the virus from multiplying inside your body. Paxlovid is available by prescription only.

Eligibility Criteria

To qualify for Paxlovid, you must meet all of the following criteria.

  • You test positive for SARS-CoV-2 (virus that causes COVID-19).
  • You currently have COVID-19 symptoms that began within the last five days.
  • You are not newly on oxygen or on an increased oxygen supply.
  • You are not hospitalized.
  • You are at high risk for severe illness from COVID-19 due to your age and certain medical conditions, including being severely immunocompromised.

Pregnant or immunocompromised people may be eligible for Paxlovid if monoclonal antibody treatment is unavailable.

Paxlovid Side Effects

Paxlovid interacts with multiple medications, which may lead to serious or life-threatening reactions. Before you are given a prescription for Paxlovid, you will need to be screened by your provider to ensure this treatment is safe for you. Many people will need to have their kidneys checked to see if they are eligible for treatment.

Getting Screened for Outpatient COVID-19 Treatment

Treatments are only for people at highest risk for hospitalization from COVID-19. All treatment options are subject to availability.

If you meet the eligibility criteria for any of the COVID-19 outpatient treatments, please call University of Utah Health at 801-213-2130 for further screening. Please have a list of your current medications before you call.

Evusheld: COVID-19 Preventive Therapy

Evusheld is a combination of two long-acting monoclonal antibodies (lab-made proteins that mimic the body's immune system to fight off infection). It is given as an intramuscular injection into your body before you are exposed to the virus that causes COVID-19. Evusheld is used as a preventive therapy only and does not treat COVID-19.

Eligibility Criteria

To qualify for Evusheld, you must be 18 years of age or older and meet all of the following criteria.

  • You are not currently infected with COVID-19.
  • You have not been knowingly exposed to someone infected with COVID-19.
  • You are moderately or severely immunocompromised (see conditions) and are unlikely to develop a strong immune response after COVID-19 vaccination or you can't get the COVID-19 vaccine due to a history of severe allergic reactions to its ingredients.  

Talk to your specialty provider to see if you qualify for Evusheld. You must have a referral and prescription from your provider to get this preventive therapy. 

Hear From Our Specialists

View More in Health Feed