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Michelle E. Schober, M.D., M.S.

Specialties

Languages

  • English
  • Spanish

Clinical Details

Locations

Schedule An Appointment Clinical Office Address
Primary Children's Hospital
Pediatric Intensive Care Unit
100 N Mario Capecchi Drive
Salt Lake City, UT 84113

Bio

Dr. Michelle Schober is a pediatrician who specializes in Pediatric Critical Care Medicine. She attends in the Pediatric Intensive Care Unit at Primary Children's Medical Center, where she is responsible for critically ill children whose ages span from newborn to 21 years old. She helps train residents and fellows in the care of critically ill children. Dr. Schober devotes her non-clinical time to research in the area of pediatric traumatic brain injury using a bench-to-bedside approach.

Board Certification and Academic Information

Academic Departments Pediatrics - Associate Professor
Academic Divisions Pediatric Critical Care
Board Certification American Board of Pediatrics (Pediatrics)
American Board of Pediatrics (Sub: Crit Care Med)

Academic Profile

Research Interests

  • Acute and Longitudinal Functional Outcomes in Pediatric Traumatic Brain Injury
  • Neuropharmacology in the Management of Acquired Brain Injury
  • Pediatric Traumatic Brain Injury

Board Certification and Academic Information

Academic Departments Pediatrics - Associate Professor
Academic Divisions Pediatric Critical Care
Board Certification American Board of Pediatrics (Pediatrics)
American Board of Pediatrics (Sub: Crit Care Med)

Academic Office Locations

Academic Office Phone Number Academic Office Address
(801) 585-3907 Williams Building
Pediatric Critical Care
295 Chipeta Way
Salt Lake City, UT 84108

Academic Bio

My research focus is cognitive outcome after pediatric traumatic brain injury (TBI) with an emphasis on pre-clinical and translational approaches. Specifically, I am interested in endogenous repair mechanisms, putative candidate therapies, and the potentially detrimental effects of the sedatives and analgesics that are used clinically after TBI. I believe that a bench-to-beside approach offers a way to study mechanisms of disease with the goal of advancing clinical care.

After joining the faculty at the University of Utah, I obtained a Master’s degree in Clinical Investigation with an emphasis on basic science research and Neuroscience. This training program prepares physicians for translational research. I was funded by a Child Health Research Career Development Award in May 2010 to study short and long-term effects of erythropoietin administration on molecular, histologic and functional outcomes in a rat pup model of pediatric TBI. Manuscripts based on this research are in progress.

I have been funded as a lead PI since May 2011 to conduct a prospective observational study of children admitted to the pediatric intensive care unit for severe traumatic brain injury. Using cerebrospinal fluid collected from TBI patients over time, I will measure breakdown products of a brain-specific protein to study patterns of cell death, and levels of endogenously produced erythropoietin, after pediatric TBI. In addition, I have measured these breakdown products in the hippocampus and cortex of rat pup brains after TBI. Together with the other co-PIs, we are collecting clinical, demographic and laboratory data, including EEG patterns on these patients as well as data regarding functional outcome after TBI. Finally, we are creating a serum and CSF bank using samples from children with severe TBI. I also was funded in January 2013 as a CoPI to determine if the dietary DHA intake/DHA blood levels of high school athletes at risk for concussion correlate with concussion severity. In parallel, I am examining the impact of DHA supplementation in my rodent model of TBI expanded to include "adolescent" rats as well as rat pups. I am involved in creating a consortium of researchers in TBI at the University of Utah.

Once our current observational study is complete, I plan to proceed to an interventional study possibly of EPO or DHA to improve cogntive outcome in children after TBI. Preliminary data will come from our database, EEG and laboratory results using CSF and blood collected.

Education

Education History

Type School Degree
Graduate Training University of Utah
Clinical Investigation
M.S.
Fellowship University of Miami Jackson Memorial Hospital
Pediatric Critical Care
Fellow
Fellowship University of Miami Jackson Memorial Hospital
Pediatric Critical Care
Fellow
Residency University of Miami Jackson Memorial Hospital
Pediatrics
Resident
Internship University of Miami Jackson Memorial Hospital
Pediatrics
Intern
Professional Medical Instituto Ciencias de la Salud
Medicine
M.D.
Undergraduate Emory University

Publications

Selected Provider Publications

Clinical Trials

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