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Julio Delgado, M.D.

Specialties

  • Pathology, Clinical

Languages

  • English
  • Spanish

Clinical Details

Locations

Schedule An Appointment Clinical Office Address
(801) 583-2787 ARUP
546 Chipeta Way
Salt Lake City, UT 84108

Bio

Dr. Delgado is the group medical director of the Immunology Division and co-executive director of the Institute for Clinical and Experimental Pathology at ARUP, as well as an associate professor of pathology at the University of Utah School of Medicine. He is board certified in clinical pathology and histocompatibility laboratory testing by the American Board of Pathology and the American Board of Histocompatibility and Immunogenetics.

Board Certification and Academic Information

Academic Departments Pathology - Associate Professor
Academic Divisions Clinical Pathology
Board Certification American Board of Pathology (Clinical Path)

Academic Profile

Research Interests

  • Epitopes, T-Lymphocyte
  • Transplantation Immunology
  • Antigen Presentation
  • Proteomics
  • Histocompatibility Testing
  • Post-Transplant Monitoring

Board Certification and Academic Information

Academic Departments Pathology - Associate Professor
Academic Divisions Clinical Pathology
Board Certification American Board of Pathology (Clinical Path)

Academic Office Locations

Academic Office Phone Number Academic Office Address
Emma Eccles Jones Research Building
Dept. of Pathology
15 North Medical Drive East
Salt Lake City, UT 84112

Academic Bio

Dr. Delgado received his MD from Universidad Industrial de Santander in Colombia and his MS degree in epidemiology from the Harvard School of Public Health, completing both his clinical residency training in clinical pathology and his research fellowship in immunology and immunogenetics at the Harvard Medical School.

Education

Education History

Type School Degree
Graduate Training Harvard School of Public Health
Epidemiology
M.S.
Postdoctoral Training CBR Institute for Biomedical Research
Immunology Research
Postdoctoral Training
Fellowship Harvard Medical School
Pathology
Fellow
Chief Resident Brigham and Women's Hospital
Pathology
Chief Resident
Postdoctoral Fellowship Dana-Farber Cancer Institute
Immunogenetics
Postdoctoral Fellow
Professional Medical Universidad Industrial de Santander
Medicine
M.D.

Publications

Selected Provider Publications

Journal Article

  1. Vonderheid EC, Pavlov I, Delgado JC, Martins TB, Telang GH, Hess AD, Kadin M(2014)Prognostic factors and risk stratification in early mycosis fungoides.  Leukemia and Lymphoma, 55(1),44-50
  2. Heikal NM, Bader FM, Martins TB, Pavlov IY, Wilson AR, Barakat M, Stehlik J, Kfoury AG, Gilbert EM, Delgado JC, Hill H(2013)Immune function surveillance: association with rejection, infection and cardiac allograft vasculopathy.  Transplantation Proceedings, 45(1),376-82
  3. Cronin K, Escobar H, Szekeres K, Reyes-Vargas E, Rockwood AL, Lloyd MC, Delgado JC, Blanck (2013)Regulation of HLA-DR peptide occupancy by histone deacetylase inhibitors.  Human Vaccines & Immunotherapeutics, 9(4),
  4. Kanaseki T, Lind KC, Escobar H, Nagarajan N, Reyes-Vargas E, Rudd B, Rockwood AL, Van Kaer L, Sato N, Delgado JC, Shastri (2013)ERAAP and Tapasin Independently Edit the Amino and Carboxyl Termini of MHC Class I Peptides.  Journal of Immunology, 191(4),1547-55
  5. Ravkov EV, Pavlov IY, Martins TB, Gleich GJ, Wagner LA, Hill HR, Delgado J(2013)Identification and validation of shrimp-tropomyosin specific CD4 T cell epitopes.  Human Immunology, 74(12),1542-9
  6. Kadin ME, Pavlov IY, Delgado JC, Vonderheid E(2012)High soluble CD30, CD25, and IL-6 may identify patients with worse survival in CD30+ cutaneous lymphomas and early mycosis fungoides.  Journal of Investigative Dermatology, The, 132(3 Pt 1),703-10
  7. Taborda NA, Catano JC, Delgado JC, Rugeles MT, Montoya C(2012)Higher SLPI expression, lower immune activation, and increased frequency of immune cells in a cohort of Colombian HIV-1 controllers.  JAIDS, 60(1),12-9
  8. Wang S, Delgado JC, Ravkov E, Eckels DD, Georgelas A, Pavlov IY, Cusick M, Sebastian K, Gleich GJ, Wagner L(2012)Penaeus monodon tropomyosin induces CD4 T-cell proliferation in shrimp-allergic patients.  Human Immunology, 73(4),426-31
  9. Cho HI, Reyes-Vargas E, Delgado JC, Celis (2012)A potent vaccination strategy that circumvents lymphodepletion for effective antitumor adoptive T-cell therapy.  Cancer Research, 72(8),1986-95
  10. Escobar H, Reyes-Vargas E, Jensen PE, Delgado JC, Crockett D(2011)Utility of Characteristic QTOF MS/MS Fragmentation for MHC Class I Peptides.  Journal of Proteome Research, 10(5),2494-507
  11. Profaizer T, Eckels D, Delgado J(2011)Celiac disease and HLA typing using real-time PCR with melting curve analysis.  Tissue Antigens, 78(1),31-7
  12. Kincaid EZ, Che JW, York I, Escobar H, Reyes-Vargas E, Delgado JC, Welsh RM, Karow ML, Murphy AJ, Valenzuela DM, Yancopoulos GD, Rock K(2011)Mice completely lacking immunoproteasomes show major changes in antigen presentation.  Nature Immunology, 13(2),129-35
  13. Blanchard N, Kanaseki T, Escobar H, Delebecque F, Nagarajan NA, Reyes-Vargas E, Crockett DK, Raulet DH, Delgado JC, Shastri (2010)Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I Peptide repertoire in normal and virus-infected cells.  Journal of Immunology, 184(6),3033-42
  14. Delgado JC, Escobar H, Crockett DK, Reyes-Vargas E, Jensen P(2009)Identification of naturally processed ligands in the C57BL/6 mouse using large-scale mass spectrometric peptide sequencing and bioinformatics prediction.  Immunogenetics, 61(3),241-6
  15. Delgado JC, Fuller A, Ozawa M, Smith L, Terasaki PI, Shihab FS, Eckels D(2009)No occurrence of de novo HLA antibodies in patients with early corticosteroid withdrawal in a 5-year prospective randomized study.  Transplantation, 87(4),546-8
  16. Chen LC, Delgado JC, Jensen PE, Chen (2009)Direct expansion of human allospecific FoxP3+CD4+ regulatory T cells with allogeneic B cells for therapeutic application.  Journal of Immunology, 183(6),4094-102
  17. Stehlik J, Islam N, Hurst D, Kfoury AG, Movsesian MA, Fuller A, Delgado JC, Hammond ME, Gilbert EM, Renlund DG, Bader F, Fisher PW, Bull DA, Singhal AK, Eckels D(2009)Utility of virtual crossmatch in sensitized patients awaiting heart transplantation.  The Journal of Heart and Lung Transplantation, 28(11),1129-34
  18. Delgado JC, Pavlov IY, Shihan F(2009)Post-transplant increased levels of serum sCD30 is a marker for prediction of kidney allograft loss in a 5-year prospective study  Transplant Immunology, 22(1-2),1-4
  19. Bedoya VI, Jaimes FA, Delgado JC, Rugeles C, Usuga X, Zapata W, Castano ME, Boasso A, Shearer G, Rugeles M(2008)Fetal-maternal HLA-A and -B discordance is associated with placental RNase expression and anti-HIV-1 activity.  Current HIV Research (electronic), 6(4),380-7
  20. Escobar H, Crockett DK, Reyes-Vargas E, Baena A, Rockwood AL, Jensen PE, Delgado J(2008)Large scale mass spectrometric profiling of peptides eluted from HLA molecules reveals N-terminal-extended peptide motifs.  Journal of Immunology, 181(7),4874-82
  21. Delgado JC, Baena A, Thim S, Goldfeld A(2006)Aspartic acid homozygosity at codon 57 of HLA-DQ beta is associated with susceptibility to pulmonary tuberculosis in Cambodia.  Journal of Immunology, 176(2),1090-7
  22. Husain Z, Almeciga I, Delgado JC, Clavijo OP, Castro JE, Belalcazar V, Pinto C, Zuniga J, Romero V, Yunis E(2006)Increased FasL expression correlates with apoptotic changes in granulocytes cultured with oxidized clozapine.  Toxicology and Applied Pharmacology, 214(3),326-34
  23. Thim S, Sath S, Sina M, Tsai EY, Delgado JC, Shapiro AE, Barry CE 3rd, Glaziou P, Goldfeld A(2004)A community-based tuberculosis program in Cambodia.  JAMA: The Journal of the American Medical Association, 292(5),566-8
  24. Delgado JC, Quinones-Berrocal J, Thim S, Miranda LF, Goldfeld A(2004)Diagnostic and clinical implications of response to tuberculin in two ethnically distinct populations from Peru and Cambodia.  International Journal of Tuberculosis and Lung Disease, 8(8),982-7
  25. Delgado JC, Leung JY, Baena A, Clavijo OP, Vittinghoff E, Buchbinder S, Wolinsky S, Addo M, Walker BD, Yunis EJ, Goldfeld A(2003)The -1030/-862-linked TNF promoter single-nucleotide polymorphisms are associated with the inability to control HIV-1 viremia.  Immunogenetics, 55(7),497-501
  26. Delgado JC, Tsai EY, Thim S, Baena A, Boussiotis VA, Reynes JM, Sath S, Grosjean P, Yunis EJ, Goldfeld A(2002)Antigen-specific and persistent tuberculin anergy in a cohort of pulmonary tuberculosis patients from rural Cambodia.  Proceedings of the National Academy of Sciences of the United States of America, 99(11),7576-81
  27. Delgado JC, Baena A, Thim S, Goldfeld A(2002)Ethnic-specific genetic associations with pulmonary tuberculosis.  Journal of Infectious Diseases, 186(10),1463-8
  28. Baena A, Leung JY, Sullivan AD, Landires I, Vasquez-Luna N, Quinones-Berrocal J, Fraser PA, Uko GP, Delgado JC, Clavijo OP, Thim S, Meshnick SR, Nyirenda T, Yunis EJ, Goldfeld A(2002)TNF-alpha promoter single nucleotide polymorphisms are markers of human ancestry.  Genes and Immunity, 3(8),482-7
  29. Flores-Villanueva PO, Yunis EJ, Delgado JC, Vittinghoff E, Buchbinder S, Leung JY, Uglialoro AM, Clavijo OP, Rosenberg ES, Kalams SA, Braun JD, Boswell SL, Walker BD, Goldfeld A(2001)Control of HIV-1 viremia and protection from AIDS are associated with HLA-Bw4 homozygosity.  Proceedings of the National Academy of Sciences of the United States of America, 98(9),5140-5
  30. Delgado JC, Greene MF, Winkelman JW, Tanasijevic M(2000)Comparison of disaturated phosphatidylcholine and fetal lung maturity surfactant/albumin ratio in diabetic and nondiabetic pregnancies.  American Journal of Clinical Pathology, 113(2),233-9
  31. Boussiotis VA, Tsai EY, Yunis EJ, Thim S, Delgado JC, Dascher CC, Berezovskaya A, Rousset D, Reynes JM, Goldfeld A(2000)IL-10-producing T cells suppress immune responses in anergic tuberculosis patients.  Journal of Clinical Investigation, 105(9),1317-25
  32. Clavijo OP, Delgado JC, Yu N, Fraser PA, Yunis E(1999)HLA-Cw*1701 is associated with two sub-Saharan African-derived HLA haplotypes: HLA-B*4201, DRB1*03 and HLA-B*4202 without DRB1*03.  Tissue Antigens, 54(3),303-6
  33. Goldfeld AE, Delgado JC, Thim S, Bozon MV, Uglialoro AM, Turbay D, Cohen C, Yunis E(1998)Association of an HLA-DQ allele with clinical tuberculosis.  JAMA: The Journal of the American Medical Association, 279(3),226-8
  34. Weinreb S, Delgado JC, Clavijo OP, Yunis EJ, Bayer-Zwirello L, Polansky L, Deluhery L, Cohn G, Yao JT, Stec TC, Higby D, Anderzejewski (1998)Transplantation of unrelated cord blood cells.  Bone Marrow Transplantation, 22(2),193-6
  35. Clavijo OP, Delgado JC, Awdeh ZL, Fici D, Turbay D, Alper CA, Truedsson L, Yunis E(1998)HLA-Cw alleles associated with HLA extended haplotypes and C2 deficiency.  Tissue Antigens, 52(3),282-5
  36. Uglialoro AM, Turbay D, Pesavento PA, Delgado JC, McKenzie FE, Gribben JG, Hartl D, Yunis EJ, Goldfeld A(1998)Identification of three new single nucleotide polymorphisms in the human tumor necrosis factor-alpha gene promoter.  Tissue Antigens, 52(4),359-67
  37. Turbay D, Lieberman J, Alper CA, Delgado JC, Corzo D, Yunis JJ, Yunis E(1997)Tumor necrosis factor constellation polymorphism and clozapine-induced agranulocytosis in two different ethnic groups.  Blood, 89(11),4167-74
  38. Bozon MV, Delgado JC, Selvakumar A, Clavijo OP, Salazar M, Ohashi M, Alosco SM, Russell J, Yu N, Dupont B, Yunis E(1997)Error rate for HLA-B antigen assignment by serology: implications for proficiency testing and utilization of DNA-based typing methods.  Tissue Antigens, 50(4),387-94
  39. Schultze JL, Michalak S, Seamon MJ, Dranoff G, Jung K, Daley J, Delgado JC, Gribben JG, Nadler L(1997)CD40-activated human B cells: an alternative source of highly efficient antigen presenting cells to generate autologous antigen-specific T cells for adoptive immunotherapy.  Journal of Clinical Investigation, 100(11),2757-65
  40. Mobini N, Yunis EJ, Alper CA, Yunis JJ, Delgado JC, Yunis DE, Firooz A, Dowlati Y, Bahar K, Gregersen PK, Ahmed A(1997)Identical MHC markers in non-Jewish Iranian and Ashkenazi Jewish patients with pemphigus vulgaris: possible common central Asian ancestral origin.  Human Immunology, 57(1),62-7
  41. Delgado JC, Hameed A, Yunis JJ, Bhol K, Rojas AI, Rehman SB, Khan AA, Ahmad M, Alper CA, Ahmed AR, Yunis E(1997)Pemphigus vulgaris autoantibody response is linked to HLA-DQB1*0503 in Pakistani patients.  Human Immunology, 57(2),110-9
  42. Delgado JC, Turbay D, Yunis EJ, Yunis JJ, Morton ED, Bhol K, Norman R, Alper CA, Good RA, Ahmed (1996)A common major histocompatibility complex class II allele HLA-DQB1* 0301 is present in clinical variants of pemphigoid.  Proceedings of the National Academy of Sciences of the United States of America, 93(16),8569-71
  43. Bozon MV, Delgado JC, Turbay D, Salazar M, Granja CB, Alosco SM, Dupont B, Yunis E(1996)Comparison of HLA-A antigen typing by serology with two polymerase chain reaction based DNA typing methods: implications for proficiency testing.  Tissue Antigens, 47(6),512-8
  44. Delgado JC, Yunis DE, Bozon MV, Salazar M, Deulofeut R, Turbay D, Mehra NK, Pasricha JS, Raval RS, Patel H, Shah BK, Bhol K, Alper CA, Ahmed AR, Yunis E(1996)MHC class II alleles and haplotypes in patients with pemphigus vulgaris from India.  Tissue Antigens, 48(6),668-72

Review

  1. Delgado JC, Eckels D(2008)Positive B-cell only flow cytometric crossmatch: implications for renal transplantation.  Experimental and Molecular Pathology, 85(1),59-63

Commentary

  1. Delgado JC, Jensen P(2008)Cat and mouse.  Nature Immunology, 9(8),829-30
  2. Delgado JC, Jensen P(2007)Trimming creates a new self-image.  Nature Immunology, 8(1),21-2

Clinical Trials

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