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Perry F. Renshaw, MD, PhD, MBA

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Languages Spoken: English

Perry Renshaw, MD, PhD, MBA, is a graduate of the University of Pennsylvania Perelman School of Medicine in Philadelphia, PA. He also completed his PhD in Biophysics at the University of Pennsylvania and his MBA at the McCallum Graduate School of Business, Bentley College, in Waltham, MA. Dr. Renshaw serves as the Medical Director of the VISN 19 Mental Illness Research, Education and Clinical Center (MIRECC) at the Salt Lake City Veterans Affairs Medical Center. His training as a biophysicist and psychiatrist has led to a primary research interest in the use of multinuclear magnetic resonance spectroscopy (MRS) neuroimaging to identify changes in brain chemistry associated with psychiatric disorders and substance abuse. Over the past 20 years, he has conducted more than 1,000 MRS brain scans of individuals with mood disorders, with the goal of characterizing the cross-sectional and longitudinal alterations in brain chemistry associated with mood disorders and their treatment. As Professor in the Department of Psychiatry, he has a notable publication record having served as an author on more than 300 publications. His research projects have been funded by the NIH for 18 years, including a NIDA K05 and a collaborative R01 grant.

Specialties

  • Psychiatry

Board Certification and Academic Information

Academic Departments Psychiatry - Professor
Academic Divisions Adult Psychiatry
Board Certification American Board of Psychiatry & Neurology (Psychiatry)

Perry Renshaw, MD, PhD, MBA, is a graduate of the University of Pennsylvania Perelman School of Medicine in Philadelphia, PA. He also completed his PhD in Biophysics at the University of Pennsylvania and his MBA at the McCallum Graduate School of Business, Bentley College, in Waltham, MA. Dr. Renshaw serves as the Medical Director of the VISN 19 Mental Illness Research, Education and Clinical Center (MIRECC) at the Salt Lake City Veterans Affairs Medical Center. His training as a biophysicist and psychiatrist has led to a primary research interest in the use of multinuclear magnetic resonance spectroscopy (MRS) neuroimaging to identify changes in brain chemistry associated with psychiatric disorders and substance abuse. Over the past 20 years, he has conducted more than 1,000 MRS brain scans of individuals with mood disorders, with the goal of characterizing the cross-sectional and longitudinal alterations in brain chemistry associated with mood disorders and their treatment. As Professor in the Department of Psychiatry, he has a notable publication record having served as an author on more than 300 publications. His research projects have been funded by the NIH for 18 years, including a NIDA K05 and a collaborative R01 grant.

Academic Locations

Board Certification and Academic Information

Academic Departments Psychiatry - Professor
Academic Divisions Adult Psychiatry
Board Certification American Board of Psychiatry & Neurology (Psychiatry)

Education History

Graduate Training Bentley University
Business Administration
M.B.A., 2007
Fellowship Massachusetts General Hospital
Neuroscience
Fellow, 1992
Residency Massachusetts General Hospital
Psychiatry
Resident, 1991
Internship Brigham and Women's Hospital
Internal Medicine
Intern, 1989
Postdoctoral Fellowship University of Pennsylvania
Metabolic NMR
Postdoctoral Fellow, 1988
Professional Medical University of Pennsylvania
Medicine
M.D., 1988
Doctoral Training University of Pennsylvania
Biophysics
Ph.D., 1987
Undergraduate Massachusetts Institute of Technology
Chemistry
S.B., 1982

Selected Publications - Journal Articles

Journal Article

  1. Joo Y, Lee S, Hwang J, Kim J, Cheon YH, Lee H, Kim S, Yurgelun-Todd DA, Renshaw PF, Yoon S, Lyoo IK (2022). Differential alterations in brain structural network organization during addiction between adolescents and adults. Psychol Med, 1-12.
  2. Huber RS, Sheth C, Renshaw PF, Yurgelun-Todd DA, McGlade EC (2020). Suicide Ideation and Neurocognition Among 9- and 10-Year Old Children in the Adolescent Brain Cognitive Development (ABCD) Study. Arch Suicide Res, 26(2), 641-655.
  3. Subramaniam P, Prescot A, McGlade E, Renshaw P, Yurgelun-Todd D (2022). Examination of gamma-aminobutyric acid and glutamate-glutamine levels in association with impulsive behavior in adolescent marijuana users. Drug Alcohol Depend, 233, 109326.
  4. Ma J, Lyoo IK, Renshaw PF, Yurgelun-Todd DA (2022). Effect of cannabinoids on brain metabolites: A review of animal and human studies. Exp Clin Psychopharmacol.
  5. Jeong H, Yoon S, Sung YH, Kim J, Lyoo IK, Yurgelun-Todd DA, Renshaw PF (2021). Effects of cytidine-5'-diphosphate choline on gray matter volumes in methamphetamine-dependent patients: A randomized, double-blind, placebo-controlled study. J Psychiatr Res, 143, 215-221.
  6. Palmer CE, Sheth C, Marshall AT, Adise S, Baker FC, Chang L, Clark DB, Coronado C, Dagher RK, Diaz V, Dowling GJ, Gonzalez MR, Haist F, Herting MM, Huber RS, Jernigan TL, LeBlanc K, Lee K, Lisdahl KM, Neigh G, Patterson MW, Renshaw P, Rhee KE, Tapert S, Thompson WK, Uban K, Sowell ER, Yurgelun-Todd D (2021). A Comprehensive Overview of the Physical Health of the Adolescent Brain Cognitive Development Study Cohort at Baseline. Front Pediatr, 9, 734184.
  7. Han DH, Bae S, Hong J, Kim SM, Son YD, Renshaw P (2019). Resting-State fMRI Study of ADHD and Internet Gaming Disorder. J Atten Disord, 25(8), 1080-1095.
  8. Li Y, Thompson WK, Reuter C, Nillo R, Jernigan T, Dale A, Sugrue LP, ABCD Consortium, Brown J, Dougherty RF, Rauschecker A, Rudie J, Barch DM, Calhoun V, Hagler D, Hatton S, Tanabe J, Marshall A, Sher KJ, Heeringa S, Hermosillo R, Banich MT, Squeglia L, Bjork J, Zucker R, Neale M, Herting M, Sheth C, Huber R, Reeves G, Hettema JM, Howlett KD, Cloak C, Baskin-Sommers A, Rapuano K, Gonzalez R, Karcher N, Laird A, Baker F, James R, Sowell E, Dick A, Hawes S, Sutherland M, Bagot K, Bodurka J, Breslin F, Morris A, Paulus M, Gray K, Hoffman E, Weiss S, Rajapakse N, Glantz M, Nagel B, Ewing SF, Goldstone A, Pfefferbaum A, Prouty D, Rosenberg M, Bookheimer S, Tapert S, Infante M, Jacobus J, Giedd J, Shilling P, Wade N, Uban K, Haist F, Heyser C, Palmer C, Kuperman J, Hewitt J, Cottler L, Isaiah A, Chang L, Edwards S, Ernst T, Heitzeg M, Puttler L, Sripada C, Iacono W, Luciana M, Clark D, Luna B, Schirda C, Foxe J, Freedman E, Mason M, McGlade E, Renshaw P, Yurgelun-Todd D, Albaugh M, Allgaier N, Chaarani B, Potter A, Ivanova M, Lisdahl K, Do E, Maes H, Bogdan R, Anokhin A, Dosenbach N, Glaser P, Heath A, Casey BJ, Gee D, Garavan HP, Dowling G, Brown S (2021). Rates of Incidental Findings in Brain Magnetic Resonance Imaging in Children. JAMA Neurol, 78(5), 578-587.
  9. Legarreta MD, Sheth C, Prescot AP, Renshaw PF, McGlade EC, Yurgelun-Todd DA (2020). An exploratory proton MRS examination of gamma-aminobutyric acid, glutamate, and glutamine and their relationship to affective aspects of chronic pain. Neurosci Res, 163, 10-17.
  10. Son YD, Han DH, Kim SM, Min KJ, Renshaw PF (2017). A functional connectivity comparison between attention deficit hyperactivity disorder and bipolar disorder in medication-naive adolescents with mood fluctuation and attention problems. Psychiatry Res Neuroimaging, 263, 1-7.
  11. Harper DG, Jensen JE, Ravichandran C, Perlis RH, Fava M, Renshaw PF, Iosifescu DV (2017). Tissue Type-Specific Bioenergetic Abnormalities in Adults with Major Depression. Neuropharmacology, 42, 876-885.
  12. Kang KD, Han DH, Kim SM, Bae S, Renshaw PF (2016). The correlation between cognitive and movement shifting and brain activity in children with ADHD. J Atten Disord, 1-10.
  13. Kim JE, Kim GH, Hwang J, Kim JY, Renshaw PF, Yurgelun-Todd DA, Kim B, Kang I, Jeon S, Ma J, Lyoo IK, Yoon S (2016). Metabolic alterations in the anterior cingulate cortex and related cognitive deficits in late adolescent methamphetamine users. Addict Biol.
  14. Harper DG, Jensen JE, Ravichandran C, Perlis RH, Fava M, Renshaw PF, Iosifescu DV (2016). Tissue-type-specific bioenergetics abnormalities in adults with major depression. 42(4), 876-885.
  15. Yoon S, Kim JE, Hwang J, Kim TS, Kang HJ, Namgung E, Ban S, Oh S, Yang J, Renshaw PF, Lyoo IK (2016). Effects of Creatine Monohydrate Augmentation on Brain Metabolic and Network Outcome Measures in Women With Major Depressive Disorder. Biol Psychiatry, 80(6), 439-47.
  16. Aydin B, Yurt A, Gkmen N, Renshaw P, Olson D, Yildiz A (2016). Trait-related alterations of N-acetylaspartate in euthymic bipolar patients: A longitudinal proton magnetic resonance spectroscopy study. J Affect Disord, 206, 315-320.
  17. Bae S, Han DH, Kim SM, Shi X, Renshaw PF (2016). Neurochemical correlates of internet game play in adolescents with attention deficit hyperactivity disorder: A proton magnetic resonance spectroscopy (MRS) study. Psychiatry Res, 254, 10-7.
  18. Kondo DG, Forrest LN, Shi X, Sung YH, Hellem TL, Huber RS, Renshaw PF (08/01/2016). Creatine target engagement with brain bioenergetics: A dose-ranging phosphorus-31 magnetic resonance spectroscopy study of adolescent females with SSRI-resistant depression. Amino Acids, 48(8), 1941-54.
  19. Jeong BS, Han DH, Kim SM, Lee SW, Renshaw PF (2016). White matter connectivity and Internet gaming disorder. Addict Biol, 21(3), 732-42.
  20. Han DH, Kim SM, Bae S, Renshaw PF, Anderson JS (2016). A failure of suppression within the default mode network in depressed adolescents with compulsive internet game play. J Affect Disord, 194, 57-64.
  21. Chung US, Han DH, Shin YJ, Renshaw PF (2016). A prosocial online game for social cognition training in adolescents with high-functioning autism: an fMRI study. Neuropsychiatr Dis Treat, 12, 651-60.
  22. Prisciandaro JJ, Schacht JP, Prescot AP, Renshaw PF, Brown TR, Anton RF (2016). Associations Between Recent Heavy Drinking and Dorsal Anterior Cingulate N-Acetylaspartate and Glutamate Concentrations in Non-Treatment-Seeking Individuals with Alcohol Dependence. Alcohol Clin Exp Res, 40(3), 491-6.
  23. Yildiz A, Aydin B, Gkmen N, Yurt A, Cohen B, Keskinoglu P, ngr D, Renshaw P (2016). Antimanic Treatment With Tamoxifen Affects Brain Chemistry: A Double-Blind, Placebo-Controlled Proton Magnetic Resonance Spectroscopy Study. Biol Psychiatry Cogn Neurosci Neuroimaging, 1(2), 125-131.

Review

  1. Smith CJ, Renshaw P, Yurgelun-Todd D, Sheth C (2022). Acute and chronic neuropsychiatric symptoms in novel coronavirus disease 2019 (COVID-19) patients: A qualitative review. [Review]. Front Public Health, 10, 772335.

Patent

  1. Yurgelun-Todd, Deborah, Renshaw, Perry (2019). Methods and compositions for improving cognitive performance 20100041621.
  2. Renshaw, Perry, Yurgelun-Todd, Deborah (2019). Methods for improving frontal brain bioenergetic metabolism 20100041620.
  3. Renshaw P, Yurgelun-Todd D (2019). Combination of Creatine, an Omega-3 Fatty Acid, and Citicoline. U.S. Patent No. PCT/US2015/014856. Washington, D.C.:U.S. Patent and Trademark Office.
  4. Rohan ML, Renshaw PF, Parrow A (2014). Magnetic field treatment techniques. U.S. Patent No. 8,702,582. Washington, D.C.:U.S. Patent and Trademark Office.
  5. Renshaw PF (2014). Predicting efficacy of psychiatric treatment. U.S. Patent No. 8,694,073. Washington, D.C.:U.S. Patent and Trademark Office.
  6. Renshaw PF (2013). Compounds for the treatment of psychiatric of substance abuse disorders. U.S. Patent No. 8,575,219. Washington, D.C.:U.S. Patent and Trademark Office.
  7. Yurgelun-Todd DA, Renshaw PF (2013). Use of secretin in treatments of disorders associated with amygdala. U.S. Patent No. 8,524,655. Washington, D.C.:U.S. Patent and Trademark Office.
  8. Rohan ML, Renshaw PF, Parrow A (2012). Magentc field treatment techniques. U.S. Patent No. 8,303,480. Washington, D.C.:U.S. Patent and Trademark Office.
  9. Renshaw PF (2011). Compounds for the treatment of psychiatric substance abuse disorders. U.S. Patent No. 7,863,254. Washington, D.C.:U.S. Patent and Trademark Office.
  10. Renshaw PF (2011). Compounds for the treatment of psychiatric or substance abuse disorders. U.S. Patent No. 8,030,294. Washington, D.C.:U.S. Patent and Trademark Office.
  11. Rohan ML, Renshaw PF, Parrow A (2011). Magnetic filed treatment techniques. U.S. Patent No. 8,047,979. Washington, D.C.:U.S. Patent and Trademark Office.
  12. Lukas SE, Renshaw PF (2011). Compounds for the treatment of marihuana dependence, withdrawal, and usage. U.S. Patent No. 7,947,611. Washington, D.C.:U.S. Patent and Trademark Office.
  13. Lukas SE, Renshaw PF (2010). Compounds for the treatment of marijuana dependence, withdrawal, and usage. U.S. Patent No. 7,947,661. Washington, D.C.:U.S. Patent and Trademark Office.
  14. Rohan ML, Parow A, Renshaw PF (2007). Magnetic field stimulation techniques. U.S. Patent No. 7,282,021. Washington, D.C.:U.S. Patent and Trademark Office.
  15. Rohan ML, Parow A, Renshaw PF (2006). Magnetic field stimulation techniques. U.S. Patent No. 7,033,312. Washington, D.C.:U.S. Patent and Trademark Office.
  16. Rohan ML, Renshaw PF, Parow A (2006). Magnetic field treatment techniques. U.S. Patent No. 8,047,979. Washington, D.C.:U.S. Patent and Trademark Office.
  17. Anderson CM, Lowen SB, Renshaw PF, Teicher MH, Maas LC (2005). Method for providing optimal drug dosage. U.S. Patent No. 6,898,455. Washington, D.C.:U.S. Patent and Trademark Office.
  18. Renshaw PF (2004). Pyrimidines, such as uridine, in treatments for patients with bipolar disorder. U.S. Patent No. 6,898,455. Washington, D.C.:U.S. Patent and Trademark Office.
  19. Ke Y, Renshaw PF, Cohen BM (2003). Two-dimensional MR spectroscopy techniques. U.S. Patent No. 6,617,169. Washington, D.C.:U.S. Patent and Trademark Office.
  20. Renshaw PF, Parow AM, Rohan M (2003). Magnetic field stimulation techniques. U.S. Patent No. 6,572.528. Washington, D.C.:U.S. Patent and Trademark Office.
  21. Renshaw PF (2003). Method and apparatus for detecting mental illness. U.S. Patent No. 6 ,400,978. Washington, D.C.:U.S. Patent and Trademark Office.
  22. Renshaw PF, Cowan RL, Frederick B (2003). Method for assessing cortical response to blue light. U.S. Patent No. 6,630.127. Washington, D.C.:U.S. Patent and Trademark Office.
  23. Renshaw PF (2000). Treatment of mental conditions including depression. U.S. Patent No. 6,258,794. Washington, D.C.:U.S. Patent and Trademark Office.
  24. Renshaw PF, Lukas SE (2000). Cytidine-containing and cytosine-containing compounds as a treatment for stimulant exposure. CIP 6,103,703. (Applications pending for use in depression, alcohol abuse/dependence, and ADHD.). U.S. Patent No. 5,958,896. Washington, D.C.:U.S. Patent and Trademark Office.
  25. Frederick B, Wald L, Renshaw PF (2000). Phased array echo-planer imaging system for fMRI. U.S. Patent No. 6,104,943. Washington, D.C.:U.S. Patent and Trademark Office.
  26. Renshaw PF, Lukas SE (2000). Cytidine-containing and cytosine-containing compounds as treatments for stimulant exposure. U.S. Patent No. 6,103,703. Washington, D.C.:U.S. Patent and Trademark Office.
  27. Maas LC, Frederick B, Renshaw PF (1998). Decoupled automated rotational and translational registration for functional MRI time series data: the DART registration algorithm. U.S. Patent No. 5,850,486. Washington, D.C.:U.S. Patent and Trademark Office.

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