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Joseph W. Rudolf

Joseph W. Rudolf, MD

Languages spoken: English
  • Specialties

    • Medical Informatics
    • Pathology, Clinical

    Board Certification

    American Board of Pathology (Clinical Path)
    American Board of Pathology (Sub: Clinical Informatics)
  • Board Certification and Academic Information

    Academic Departments Pathology -Primary
    Board Certification
    American Board of Pathology (Clinical Path)
    American Board of Pathology (Sub: Clinical Informatics)

    Education history

    Fellowship Clinical Informatics - Massachusetts General Hospital Fellow
    Clinical Pathology - Massachusetts General Hospital Chief Resident
    Residency Clinical Pathology - Massachusetts General Hospital Resident
    Medicine - University of Washington School of Medicine M.D.
    Undergraduate Major: Biology; Minor: Chemistry - Concordia College B.A.

    Selected Publications

    Journal Article

    1. Potter S, Rudolf JW, Pearson LN (2024). Rainbow phlebotomy collection and urine aliquots for emergency department add-on testing in the era of pandemic-driven supply shortages. Lab Med. (Read full article)
    2. Schmidt RL, Moore RA, Walker BS, Rudolf JW (2023). Precision quality control: a dynamic model for risk-based analysis of analytical quality. Clin Chem Lab Med. (Read full article)
    3. Schmidt RL, Moore RA, Walker BS, Rudolf JW (2022). Risk Analysis for Quality Control Part 3: Practical Application of the Precision Quality Control Model. J Appl Lab Med, 8(1), 34-40. (Read full article)
    4. Schmidt RL, Moore RA, Walker BS, Rudolf JW (2022). Risk Analysis for Quality Control Part 1: The Impact of Transition Assumptions in the Parvin Model. J Appl Lab Med, 8(1), 14-22. (Read full article)
    5. Moore RA, Rudolf JW, Schmidt RL (2022). Risk Analysis for Quality Control Part 2: Theoretical Foundations for Risk Analysis. J Appl Lab Med, 8(1), 23-33. (Read full article)
    6. Schmidt RL, Walker BS, Moore RA, Rudolf JW (2022). Impact of assay stability on the false negative and false positive rates in quality control. Clin Chim Acta, 540, 117208. (Read full article)
    7. Klein ME, Rudolf JW, Tarbunova M, Jorden T, Clark SR, Khalifa MA (2020). Real-Time Intraoperative Consultation Reporting in the Electronic Health Record. Am J Clin Pathol, 154(3), 387-393. (Read full article)
    8. Turbett SE, Anahtar MN, Pattanayak V, Azar MM, Coffey KC, Eng G, Rudolf JW, Lewandrowski KB, Baron J, Rosenberg ES, Branda JA (2019). Use of Routine Complete Blood Count Results to Rule Out Anaplasmosis Without the Need for Specific Diagnostic Testing. Clin Infect Dis, 70(6), 1215-1221. (Read full article)
    9. Uljon SN, Simmons DP, Rudolf JW, Baron JM, Dutta S, McEvoy DS, Murali M, Dighe AS (2019). Validation and Implementation of an Ordering Alert to Improve the Efficiency of Monoclonal Gammopathy Evaluation. Am J Clin Pathol, 153(3), 396-406. (Read full article)
    10. Rudolf JW, Baron JM, Dighe AS (2019). Order Indication Solicitation to Assess Clinical Laboratory Test Utilization: D-Dimer Order Patterns as an Illustrative Case. J Pathol Inform, 10, 36. (Read full article)
    11. Lewandrowski K, Keegan A, Makarenko V, Maryamchak E, Mata DA, Palte MJ, Rudolf JW, Safdar N, Schmidt RJ, Stuart L, Xiong Y, Rao L, Melanson SEF, Michael Snyder L (2018). Development of a Commercial Reference Laboratory Elective Rotation for Residents in Clinical Pathology. Am J Clin Pathol, 150(6), 485-490. (Read full article)
    12. Rudolf J, Baron J, Branda J, Lee-Lewandrowski E (2018). Laboratory Testing for Tick-Borne Infections in a Large Northeastern Academic Medical Center: An 11-Year Experience. Am J Clin Pathol, 150(5), 415-420. (Read full article)
    13. Kurant DE, Baron JM, Strazimiri G, Lewandrowski KB, Rudolf JW, Dighe AS (2018). Creation and Use of an Electronic Health Record Reporting Database to Improve a Laboratory Test Utilization Program. Appl Clin Inform, 9(3), 519-527. (Read full article)
    14. Rudolf JW, Garcia CA, Hanna MG, Williams CL, Balis UG, Pantanowitz L, Tuthill JM, Gilbertson JR, Pathology Informatics Alumni Group (2018). Career Paths of Pathology Informatics Fellowship Alumni. J Pathol Inform, 9, 14. (Read full article)
    15. Yeh DD, Chokengarmwong N, Chang Y, Yu L, Arsenault C, Rudolf J, Lee-Lewandrowski E, Lewandrowski K (2017). Total and ionized magnesium testing in the surgical intensive care unit - Opportunities for improved laboratory and pharmacy utilization. J Crit Care, 42, 147-151. (Read full article)
    16. Lin DC, Straseski JA, Schmidt RL, The Thyroid Benchmarking Group (2017). Multi-Center Benchmark Study Reveals Significant Variation in Thyroid Testing in United States. Thyroid, 27(10). (Read full article)
    17. Rudolf JW, Dighe AS, Coley CM, Kamis IK, Wertheim BM, Wright DE, Lewandrowski KB, Baron JM (2017). Analysis of Daily Laboratory Orders at a Large Urban Academic Center: A Multifaceted Approach to Changing Test Ordering Patterns. Am J Clin Pathol, 148(2), 128-135. (Read full article)
    18. Rudolf J, Jackson BR, Wilson AR, Smock KJ, Schmidt RL (2017). Organizational Benchmarks for Test Utilization Performance: An Example Based on Positivity Rates for Genetic Tests. Am J Clin Pathol, 147(4), 382-389. (Read full article)
    19. Rudolf JW, Lewandrowski EL, Lewandrowski KB, Januzzi JL, Bajwa EK, Baron JM (2016). ST2 Predicts Mortality and Length of Stay in a Critically Ill Noncardiac Intensive Care Unit Population. Am J Clin Pathol, 145(2), 203-10. (Read full article)
    20. Garcia CA, Baron JM, Beckwith BA, Brodsky V, Dighe AS, Gudewicz TM, Kim JY, Klepeis VE, Lane WJ, Lee RE, Levy BP, Mahowald MA, Mandelker D, McClintock DS, Quinn AM, Rao LK, Riedlinger GM, Rudolf J, Gilbertson JR (2015). Environmental components and methods for engaging pathology residents in informatics training. J Pathol Inform, 6, 42. (Read full article)
    21. Rudolf J, Douglass J, Baron J, Lewandrowski K (2015). Evaluation of the i-STAT point-of-care capillary whole blood hematocrit and hemoglobin: Comparison to the Siemens RAPIDLab 1200, Sysmex XE5000, and manual spun hematocrit. Clin Chim Acta, 446, 37-42. (Read full article)


    1. Bunch DR, Durant TJ, Rudolf JW (2022). Artificial Intelligence Applications in Clinical Chemistry. [Review]. Clin Lab Med, 43(1), 47-69. (Read full article)
    2. Rudolf JW, Dighe AS (2019). Decision Support Tools within the Electronic Health Record. [Review]. Clin Lab Med, 39(2), 197-213. (Read full article)
    3. Rudolf J, Lewandrowski KB (2014). Cholesterol, lipoproteins, high-sensitivity c-reactive protein, and other risk factors for atherosclerosis. [Review]. Clin Lab Med, 34(1), 113-27, vii. (Read full article)

    Case Report

    1. Pandya V, Hunsaker JJH, Laulu SL, Genzen JR, Frank EL, Johnson LM, Rudolf JW (2021). Excessively low cholesterol and triglyceride levels in an apparently healthy patient. Clin Biochem, 96, 78-81. (Read full article)


    1. Hunsaker JJH, Laulu SL, Zupan E, Patel D, Pandya V, Rudolf JW (2024). Detection of a High-Dose Hook Effect and Evaluation of Dilutions of Urine Myoglobin Specimens Using a Serum Myoglobin Assay. [Letter to the editor]. Ann Lab Med. (Read full article)
    2. Fink SL, Wener MH, Rudolf JW, Nwosu A, Tacker DH, Kadkhoda K, Tebo AE, Willrich MAV (2023). A universal reference interval for serum immunoglobulins free light chains may be outdated. [Letter to the editor]. Clin Chem Lab Med. (Read full article)
    3. Nelson HA, Genzen JR, Delgado JC, Rudolf JW (2021). An Interference in an Automated HCO3- Assay Leads to an Unexpected IgG Monoclonal Gammopathy Diagnosis. [Letter to the editor]. J Appl Lab Med, 7, 622-625. (Read full article)
    4. Willrich MAV, Long TA, Bashleben C, Fink SL, Rudolf JW, Peterson D, Wener MH, Baltaro RJ, Genzen JR, Ansari MQ, Rhoads DD, Linden MA (2020). Performance of perpendicular drop versus tangent skimming gating of M-protein in proficiency testing challenges. [Letter to the editor]. Clin Chem Lab Med, 59(1), e19-e22. (Read full article)