Marc C. Engels
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Marc C. Engels, MD, PhD

Languages spoken: English

Clinical Locations

Farmington Health Center

Farmington
801-213-3200

Redstone Health Center

Park City
435-658-9200

  • Marc Engels, M.D., Ph.D. is an Assistant Professor at the University of Utah School of Medicine. He is a cardiologist and cardiac electrophysiologist, specializing in the care of patients with heart rhythm disorders. He completed medical school as well as a Ph.D. at Leiden University in the Netherlands, followed by internal medicine residency at Emory University, cardiology fellowship at Johns Hopkins Hospital and cardiac electrophysiology fellowship at Johns Hopkins Hospital. His clinical interests include ablation of complex cardiac arrhythmias such as ventricular tachycardia, atrial fibrillation and atrial flutter, and supraventricular tachycardia, as well as device therapy including pacemakers, cardiac resynchronization therapy, ICDs, and conduction system pacing as well as leadless pacemakers, device extraction and Watchman devices. His research has focused on the fundamental mechanisms underlying heart rhythm disorders as well as cellular and molecular based arrhythmia therapies including shockless defibrillation. Dr. Engels is board certified in internal medicine and cardiovascular disease and board eligible in cardiac electrophysiology.

    Specialties

    Board Certification

    American Board of Internal Medicine (Internal Medicine)
    American Board of Internal Medicine (Sub: Cardiovascular Disease)

  • Marc Engels, M.D., Ph.D. is an Assistant Professor at the University of Utah School of Medicine. He is a cardiologist and cardiac electrophysiologist, specializing in the care of patients with heart rhythm disorders. He completed medical school as well as a Ph.D. at Leiden University in the Netherlands, followed by internal medicine residency at Emory University, cardiology fellowship at Johns Hopkins Hospital and cardiac electrophysiology fellowship at Johns Hopkins Hospital. His clinical interests include ablation of complex cardiac arrhythmias such as ventricular tachycardia, atrial fibrillation and atrial flutter, and supraventricular tachycardia, as well as device therapy including pacemakers, cardiac resynchronization therapy, ICDs, and conduction system pacing as well as leadless pacemakers, device extraction and Watchman devices. His research has focused on the fundamental mechanisms underlying heart rhythm disorders as well as cellular and molecular based arrhythmia therapies including shockless defibrillation. Dr. Engels is board certified in internal medicine and cardiovascular disease and board eligible in cardiac electrophysiology.

    Board Certification and Academic Information

    Academic Departments Internal Medicine -Primary
    Academic Divisions Cardiovascular Medicine
    Board Certification
    American Board of Internal Medicine (Internal Medicine)
    American Board of Internal Medicine (Sub: Cardiovascular Disease)

    Education history

    Fellowship Cardiac Electrophysiology - Johns Hopkins University Clinical Fellow
    Johns Hopkins University Postdoctoral Research Fellow
    Fellowship Cardiovascular - Johns Hopkins University Clinical Fellow
    Internal Medicine - Emory University School of Medicine Resident
    Doctoral Training Leiden University Medical Center, Leiden University Ph.D.
    Medicine - Leiden University Medical Center, Leiden University, Leiden M.D.
    Undergraduate Life Science and Technology - Leiden University and Delft University of Technology B.S.

    Selected Publications

    Journal Article

    1. Sani MM, Sung E, Engels M, Daimee UA, Trayanova N, Wu KC, Chrispin J (2023). Association of epicardial and intramyocardial fat with ventricular arrhythmias. Heart Rhythm, 20(12), 1699-1705. (Read full article)
    2. Sung E, Kyranakis S, Daimee UA, Engels M, Prakosa A, Zhou S, Nazarian S, Zimmerman SL, Chrispin J, Trayanova NA (2023). Evaluation of a deep learning-enabled automated computational heart modelling workflow for personalized assessment of ventricular arrhythmias. J Physiol. (Read full article)
    3. Isakadze N, Engels MC, Beer D, McClellan R, Yanek LR, Mondaloo B, Hays AG, Metkus TS, Calkins H, Barth AS (2022). C-reactive Protein Elevation Is Associated With QTc Interval Prolongation in Patients Hospitalized With COVID-19. Front Cardiovasc Med, 9, 866146. (Read full article)
    4. Daimee UA, Sung E, Engels M, Halushka MK, Berger RD, Trayanova NA, Wu KC, Chrispin J (2022). Association of left ventricular tissue heterogeneity and intramyocardial fat on computed tomography with ventricular arrhythmias in ischemic cardiomyopathy. Heart Rhythm O2, 3(3), 241-247. (Read full article)
    5. Allard-Ratick MP, Kindya BR, Khambhati J, Engels MC, Sandesara PB, Rosenson RS, Sperling LS (2019). HDL: Fact, fiction, or function? HDL cholesterol and cardiovascular risk. Eur J Prev Cardiol, 28(2), 166–173. (Read full article)
    6. Liu J, Volkers L, Jangsangthong W, Bart CI, Engels MC, Zhou G, Schalij MJ, Ypey DL, Pijnappels DA, de Vries AAF (2017). Generation and primary characterization of iAM-1, a versatile new line of conditionally immortalized atrial myocytes with preserved cardiomyogenic differentiation capacity. Cardiovasc Res, 114(14), 1848-1859. (Read full article)
    7. Khambhati J, Engels M, Allard-Ratick M, Sandesara PB, Quyyumi AA, Sperling L (2018). Immunotherapy for the prevention of atherosclerotic cardiovascular disease: Promise and possibilities. Atherosclerosis, 276, 1-9. (Read full article)
    8. Majumder R, Engels MC, de Vries AA, Panfilov AV, Pijnappels DA (2016). Islands of spatially discordant APD alternans underlie arrhythmogenesis by promoting electrotonic dyssynchrony in models of fibrotic rat ventricular myocardium. Sci Rep, 6, 24334. (Read full article)
    9. Engels MC, Askar SF, Jangsangthong W, Bingen BO, Feola I, Liu J, Majumder R, Versteegh MI, Braun J, Klautz RJ, Ypey DL, De Vries AA, Pijnappels DA (2015). Forced fusion of human ventricular scar cells with cardiomyocytes suppresses arrhythmogenicity in a co-culture model. Cardiovasc Res, 107(4), 601-12. (Read full article)
    10. Sturzu AC, Rajarajan K, Passer D, Plonowska K, Riley A, Tan TC, Sharma A, Xu AF, Engels MC, Feistritzer R, Li G, Selig MK, Geissler R, Robertson KD, Scherrer-Crosbie M, Domian IJ, Wu SM (2015). Fetal Mammalian Heart Generates a Robust Compensatory Response to Cell Loss. Circulation, 132(2), 109-21. (Read full article)
    11. Bingen BO, Engels MC, Schalij MJ, Jangsangthong W, Neshati Z, Feola I, Ypey DL, Askar SF, Panfilov AV, Pijnappels DA, de Vries AA (2014). Light-induced termination of spiral wave arrhythmias by optogenetic engineering of atrial cardiomyocytes. Cardiovasc Res, 104(1), 194-205. (Read full article)
    12. Engels MC, Rajarajan K, Feistritzer R, Sharma A, Nielsen UB, Schalij MJ, de Vries AA, Pijnappels DA, Wu SM (2013). Insulin-like growth factor promotes cardiac lineage induction in vitro by selective expansion of early mesoderm. Stem Cells, 32(6), 1493-502. (Read full article)
    13. Chen JX, Krane M, Deutsch MA, Wang L, Rav-Acha M, Gregoire S, Engels MC, Rajarajan K, Karra R, Abel ED, Wu JC, Milan D, Wu SM (2012). Inefficient reprogramming of fibroblasts into cardiomyocytes using Gata4, Mef2c, and Tbx5. Circ Res, 111(1), 50-5. (Read full article)

    Commentary

    1. Teng YK, Engels MC, van Laar JM (2008). CD22 is not expressed merely on B cells: comment on the article by Vos et al. Arthritis Rheum, 58(3), 911-2; author reply 912-3. (Read full article)