Specialties
Board Certification
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American Board of Psychiatry & Neurology (Neurology)
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Patient Rating
The patient rating score is an average of all responses on our patient experience survey. The rating averages scores for all questions about care from our providers.
The scale on which responses are measured is 1 to 5 with 5 being the best score.
Patient Comments
Patient comments are gathered from our patient experience survey and displayed in their entirety. For the convenience of our visitors, some patient comments have been translated from their original language into English while preserving their original meaning as accurately as possible. Patients are de-identified for confidentiality and patient privacy.
Dr. Frost, tested me then explained all the things that could happen, then he carefully took his time to talk about the results that could come. He gave me answers that I really needed to be able to continue.
Dr. Frost is the best for me. He never pulled a red marker out stating ¿lost cause!¿ He talked me through the whole process. (Wanted a little more help with the questions) but I really feel protected and that he is doing everything possible to give the best outcome for me. He gives me hope! Thank you, Dr. Frost!
Dr. Frost is very knowledgeable. He presents factual information. He spends time to listen to patients concerns and is very supporting helping to set and make an achievable plan to have the best possible results for the patient. I highly recommend Dr Frost and his excellent nurses and people in his team.
Dr. FROST IS THE Best Dr. FROST IS THE BEST!
Great dr. I am lucky to have him
Dr Frost is very competent. He explains things well and cares about his patients.
Dr. Nicholas Frost is WONDERFUL!!! I would Highly Recommend Him to everyone I know!!!
Excellent care
Very very helpful
Very caring and knowledgeable.
Dr. Frost is very caring and patient. He helped me understand my mental condition in a clear and concise manner that I could easily comprehend. When he prescribed my medication I understood very easily how it is going to help me. I commend him for explaining things clearly. He is not pretentious like the previous neurologist I had dealt with. Thus the reason for seeking a second opinion on my first diagnosis. I can live with my condition and accept it as one of life's challenges.
He explained what we needed to do and did what he could to move it forward. We did not receive the medication or a Rx for it. It should be sent to Bountiful Drug!
Dr. Frost was very kind and informative. He pulled up the MRI pictures and explained things in detail. Gave us a plan for follow-up testing and care.
Attentive and informative
Dr Frist is a very caring snd knowledgeable man who I trust with my brain. Thanks Doc
Kind, upfront about my condition, knowledgable, concerned about me & wanting to take care of me ASAP. ,
Dr. Frost has the time to paint a full picture and answer questions-as if he has all of the time we need
This was our most positive visit. Dr Frost was totally prepared for the virtual visit. He explained things in detail. [NAME REMOVED] got a diagnosis and suggested treatment going forward, allowing him to make his own decision. Best meeting yet!
Extremely caring and easy to talk with.
Dr Frost is competent, caring, and thorough in his treatment procedures. He explains things clearly, and seeks out any questions I may have. He's able to inquire in a way that helps to identify and treat my health problems. He seems genuinely interested in my responses.
The time spent on the tele Visit was useful
Excellent care!
Such a consummate professional
Wonderful and compassionate
I met with Dr. Frost, to get a second opinion on a diagnosis from another provider. Dr. Frost acknowledged my request. He is an excellent listener and his explainations are very easy to understand. He is genuinely interested in helping me, and in recommending additional tests. I am confident that his final diagnosis will be more accurate than the previous neurological provider
Great doctor! Would recommend him to anyone. He explains everything!
He is excellent!
Dr. Frost is personable, knowlegable and an excellent Dr. During the intake appointment, Dr. Frost was Informative, sincere, caring, insightful and very patient. I felt that we dug in & identified issues and made productive plans for going forward.
Kind and considerate. Listens and cares about my well being.
I'm very lucky to have Dr. Frost as a provider and to live so close to U of U Medical Center.
Amazing doctor who answered our questions and concerns in a manner that helped us to understand dementia and the available treatments and the expectations for each choice.
A good guy, a good neurologist. His expertise saved us from much frustration and confusion arising from prior information and testing. I drove 5 hours each way to see him 2 times. Was he worth it? Heck yes.
Dr. Frost has become one of my favorites at the U.
He explained why he thought my cognitive issues were not related to my hyperintensities. Cool.
Efficient, professional, but compassionate with a sense of humor
Was very impressed with him and his knowledge of the treatment that he was suggesting.
Dr Frost listens to our experiences and concerns and gives us choices regarding procedures and studies.
Dr. Frost is genuinely a wonderful doctor who is honest with patients, kind, and thorough. I know that I am in good hands with him and with those work work with him
Dr. Frost was great at explaining the Ct, PET and other information available to him. He was very thorough and I believe he actually cares about the patient and getting the correct diagnosis.
Excellent Doctor, would recommend to anyone!
Dr. Frost is very knowledgeable. He listens and gives honest feedback. He shares information so you can make our own decision for what is best for you. His staff is very helpful and professional-also they really care.
Knowledgeable, efficient, kind.
Dr. Frost has a great way of while being professional he explains thing well so less educated in his area of specialty can understand. He's empathetic and wants to make sure my husband is getting all care available to him.
Very skilled and quite caring
Provided exceptional communication and care for my needs. Knowledgeable, competent, caring.
He is very good but hard to see, booking apps 6 months out
He is the best!! My wife and I are very impressed with him!
As busy as this department is at present , Dr Frost genuinely focused on areas of concern and best practices moving forward.
Dr Frost is a very kind and knowledgeable doctor. We appreciate his dedication to our needs.
Love him he was interested me me and is trying to help
Great doctor
Very kind, personal & professional.
Friendly, knowledgeable, and caring physician who asked the right questions in order to formulate a treatment plan that's going to help me get better. He took his time to probe my situation, tested me in necessary areas, and even recommended a great lunch place in the facility.
Dr.Frost is extremely professional and is equally knowledgeable, he is the best!
Great doctor! I would recommend him to anyone that needs to see a Neurologist. He explains everything he is going to do.
It was encouraging to meet with Dr. Frost and have a serious discussion and investigation into that which was bugging me physically! I am very anxious that the results will be delightful.
Dr Frost is a true professional who also displays an unusual compassion for this patient and his family.
He is very professional, kind, understanding and excellent in examining things.
Dr. FROST is the absolute best Dr. I have ever met.
He knows his stuff doesn't job to a conclusion even if it's what you want. Patience and kindness he has along with great humor. We are blessed he is in our corner.
I'm very thankful for his help & devotion to my issue.
A very thorough approach!
We really appreciate his willingness to help and give us counsel for the challenge we are going through. His willingness to try to help find help and support help. Thank You
Dr. Nicholas A Frost, MD is a fine person. He makes us smile by his easy demeanor. He listened when I complained that I thought they dropped the ball on getting us back in line for the next appointment in April, after we saw him. He went to make sure that it didn't happen again and explained that a bit of a rest in between all the infusions was not a bad thing, that it lets the body get used to the meds that are being administered. I would recommend him to anyone needing care.
U of U is very lucky to have Dr Frost in their program!. I'm so happy to be his patient.
Very professional
Competent and knowledgeable.
We really appreciate his willingness to explain to us what is happening to [NAME REMOVED].
I know he is brilliant and cares about his work and patients.
Very professional, knowledgeable and caring
Dr. Frost is great he has helped me a lot
Dr. Frost is an excellent Doctor!
Dr. Frost was a pleasure to work with. He is obviously highly knowledgeable and has a very pleasant style. He is also a talented communicator who explains things clearly. I trust him implicitly with my care.
practical and thoughtful
See previous comments. Gave me what I needed but had to wait too long between test and consultation.
Dr. Frost is an exceptionally talented Neurologist. His level of expertise in understanding the complexity of Alzheimer's disease and his ability to navigate the possible treatments to delay the progress of this disease gave me great confidence and hope. I have past experience on Boards of Health systems and can say that U Health, Dr. Frost, and his team are exceptional.
Dr Nicholas Frost is one of the most caring and compassionate Doctors. He has been so kind to my husband who has dementia. I highly recommend him to anyone that is seeking care
Very helpful
Dr. Frost was kind and caring. Everything I did not understand, he rephrased so I could understand completely. He was empathetic and his questions were so thorough. I felt at ease and I am grateful I am under his care.
You can share
I feel I am in excellent hands with dr. Frost. He provided a great deal of information and left me feeling quite hopeful.
Dr Frost is the guy to go to
Dr. Frost was very patient and understanding. He was thorough and explained things well.
Dr. Frost has always taken the time to answer all of my questions. I believe he really does care about his patients and their well being. He was extremely thorough and did all the tests available that was needed to determine my diagnosis. Thank you Dr. Frost for taking such good care of me as your patient.
Gentle and kind when giving bad news.
I found Dr. Frost is very knowledgeable and thorough on his evaluation of my wife
I am extremely please with my visit with Dr. Frost
Very knowledgeable. Including information on latest treatments, positive and possible negative impacts. We appreciated Dr. Frost taking the time to explain options with the diagnosis. He also offered to speak with us further if needed. We would definitely recommend him to others.
Knowledgeable & curious
Dr. Frost is very thorough, professional, kind & good with good with his explanations.
Dr. Frost is a rare gem of a physician who listens, explains, and genuinely cares for my wellbeing. I feel absolutely confident in his management of my medical needs.
I feel confident in following the advice of Dr. Frost, based on our first visit. He seemed to be quite personable, and a quick but thorough analyst of my health needs. I am looking forward to having him help me along this path!
We are so pleased to have Neil in his care.
He needed to elaborate more with his diagnosis and reasoning behind doing his tests. I didn't really receive answers to my questions.
One of the nicest and most caring physicians we've ever met
We are so great full to have a kind provider with the expertise of Dr. Frost here in SLC
Dr. Frost is very good at helping me I just wish it didn't take so long
Great
Dr Frost and his staff have been excellent. We very much appreciate them.
Dr. Frost genuinely cares about his patients. I appreciate that he wanted to help me and validated my concerns. He explained my diagnosis thoroughly in terms I could easily understand. I understand now the cause of my symptoms.
Excellent care.
Dr. Frost talks to me and my daughters every time we meet. He keeps all the balls in the air and we know we are being heard. Very clear directives!
Dr. Frost is superb and meticulous.
Brilliant physician. Very compassionate.
Dr Nicholas Frost addressed my condition or concern for Mild Cognitive Impairment. After studies with procedures and specialist appointments, it was said that diagnostically that I met criteria for diagnosis for Mild Cognitive Impairment. Etiogically, cognitive decline was seen since my last Neuropsych Evaluation and continued neurologic work up was warranted. Dr Frost's impression and plan showed consolidation was preserved making AD or LATE unlikely but LP would show more insight. Dr Frost presented professional and skilled characteristics to determine my future diagnosis. He expressed excellent knowledge to determine my issues and he was very thorough with testing and counseling. I WILL RESPECT HIS PROFESSIONAL INSIGHT WITH HOW I SHOULD MOVE FORWARD AND I AM LOOKING FORWARD TO HIS RECOMMENDATIONS.
Extremely knowledgeable and professional!
Dr. Frost was very knowledgeable and helped both myself and my wife about what I will have in the future.
He answered my questions well.
I liked him very much. My nurse practitioner had sent me to him for a different reason than I thought she had. He explained the reasoning behind it in a nice way. So I agreed it was probably good to check me for that reason.
Dr. Frost is an exceptional medical professional, second y none!
I'm very happy with Dr Frost. He and his staff are very good.
Great experience.
Such a thoughtful, thorough doctor. I really liked his approach
He did a very good job and was very helpful
We liked Dr Frost and how he went about getting the base line history of a new patient and trying to figure the best approach to figure out cognitive decline.
I totally respect Dr. Frost and his team. He explains things so that I understand what he is going to do and what is going to happen next in my treatment plan. I am so happy that I chose to go with the U of U for my treatment plan.
We knew he understood our concerns and said he would try to help us in any way that he could.
Board Certification and Academic Information
| Academic Departments |
Neurology
-Assistant Professor Neurobiology -Adjunct Assistant Professor |
|---|---|
| Board Certification |
American Board of Psychiatry & Neurology (Neurology)
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Education history
| Undergraduate | Biochemistry, Spanish - Florida State University | B.S., B.A. |
|---|---|---|
| Professional Medical | Neuroscience - University of Maryland School of Medicine | M.D., Ph.D. |
| Internship | Internal Medicine - University of California, San Francisco | Intern |
| Residency | Neurology - University of California, San Francisco | Resident |
| Research Fellow | R25 Research Fellowship in circuit disorders underlying abnormal behavior - University of California, San Francisco | Postdoctoral Fellow |
Selected Publications
Journal Article
- Frost NA, Shroff H, Kong H, Betzig E, Blanpied TA (2010). Single-molecule discrimination of discrete perisynaptic and distributed sites of actin filament assembly within dendritic spines. Neuron, 67(1), 86-99.
- Frost NA, Kerr JM, Lu HE, Blanpied TA (2010). A network of networks: cytoskeletal control of compartmentalized function within dendritic spines. Curr Opin Neurobiol, 20(5), 578-87.
- MacGillavry HD, Kerr JM, Kassner J, Frost NA, Blanpied TA (2016). Shank-cortactin interactions control actin dynamics to maintain flexibility of neuronal spines and synapses. Eur J Neurosci, 43(2), 179-93.
- Gerdes MJ, Myakishev M, Frost NA, Rishi V, Moitra J, Acharya A, Levy MR, Park SW, Glick A, Yuspa SH, Vinson C (2006). Activator protein-1 activity regulates epithelial tumor cell identity. Cancer Res, 66(15), 7578-88.
- Lieberman JA, Frost NA, Hoppert M, Fernandes PJ, Vogt SL, Raivio TL, Blanpied TA, Donnenberg MS (2012). Outer membrane targeting, ultrastructure, and single molecule localization of the enteropathogenic Escherichia coli type IV pilus secretin BfpB. J Bacteriol, 194(7), 1646-58.
- Jensen CS, Watanabe S, Rasmussen HB, Schmitt N, Olesen SP, Frost NA, Blanpied TA, Misonou H (2014). Specific sorting and post-Golgi trafficking of dendritic potassium channels in living neurons. J Biol Chem, 289(15), 10566-81.
- Lu HE, MacGillavry HD, Frost NA, Blanpied TA (2014). Multiple spatial and kinetic subpopulations of CaMKII in spines and dendrites as resolved by single-molecule tracking PALM. J Neurosci, 34(22), 7600-10.
- Parikh RV, Frost NA, Green A, Dandu M (2014). A Leathery Lining. J Gen Intern Med, 29(1), 243.
- Weinman EJ, Steplock D, Cha B, Kovbasnjuk O, Frost NA, Cunningham R, Shenolikar S, Blanpied TA, Donowitz M (2009). PTH transiently increases the percent mobile fraction of Npt2a in OK cells as determined by FRAP. Am J Physiol Renal Physiol, 297(6), F1560-5.
- Frost NA, Haggart A, Sohal VS (2021). Dynamic patterns of correlated activity in the prefrontal cortex encode information about social behavior. PLoS Biol, May 3;19(5), e3001235.
- Frost NA, Lu HE, Blanpied TA (2012). Optimization of cell morphology measurement via single-molecule tracking PALM. PLoS One, 7(5), e36751.
- Shin D, Kim CN, Ross J, Hennick KM, Wu SR, Paranjape N, Leonard R, Wang JC, Keefe MG, Pavlovic BJ, Donohue KC, Moreau C, Wigdor EM, Larson HH, Allen DE, Cadwell CR, Bhaduri A, Popova G, Bearden CE, Pollen AA, Jacquemont S, Sanders SJ, Haussler D, Wiita AP, Frost NA, Sohal VS, Nowakowski TJ (2024). Thalamocortical organoids enable in vitro modeling of 22q11.2 microdeletion associated with neuropsychiatric disorders. Cell Stem Cell, 31(3), 421-432.e8.
- Frost NA, Donohue KC, Sohal V (2023). Context-invariant socioemotional encoding by prefrontal ensembles. bioRxiv.
- Walker H, Frost N (2024). Distinct transcriptional programs define a heterogeneous neuronal ensemble for social interaction. iScience, 27(7), 110355.
- Walker H, Frost N (2024). Protocol for the generation of single-nuclei RNA-seq libraries and quantification of heterogeneous cell types activated during social interaction. STAR protocols, 5(4), 103395.
- Canales CP, Lozano SA, Frost NA, Cichewicz K, Amaral W, Seban N, Fenton E, Wade A, Chu N, Smith E, Ardekani C, Frank S, Bennett J, Lavenex P, Kopley-Smith A, Rahbarian D, Corea M, Perla D, Davis L, Zhu J, Ortiz R, Beauregard P, Morse S, Baker J, Sun J, Ma B, Lu J, Sohal VS, Amaral DG, Zuo Y, Nord A (2025). Persistent cortical excitatory neuron dysregulation in adult Chd8 haploinsufficient mice. Research square,
- Walker H, Kwak D, Devaraju P, Curd BC, Chikuni AM, Frost N (2025). Impaired Spatiotemporal Encoding of Social Behavior and Anxiety in the Prefrontal Cortex of Mice Lacking ASD-Risk Gene Shank3. bioRxiv,
- Frost NA, Donohue KC, Kwak D, Sohal V (2025). Context-invariant socioemotional encoding by prefrontal ensembles. Nature communications, 16(1), 5455.
- Gatlin RE, Gagon J, Kwak D, Park S, Walker H, Kronheim L, Everett T, Covington A, Fluck MM, Zickmund T, Frost NA, Zelikowsky (2025). Co-release of opposing signaling molecules controls the escalation and release of aggression. bioRxiv,
- Ngam PI, Anzai Y, Cliatt Brown CJ, Frost NA, Keown Sorweid M, Thientunyakit T, Minoshima S, Alzheimer's Disease Neuroimaging Initiativ (2026). Copathologies of Limbic-Predominant Age-Related TDP-43 Encephalopathy and Alzheimer Disease: [(18)F]FDG PET Statistical Mapping and Quantitative MRI Volumetry. Journal of nuclear medicine,
- Curd BC, Zubrick C, Brown CJC, Sorweid MK, Dehoney SB, Anzai Y, Minoshima S, Parks AL, Frost N (2026). Real-world experience with lecanemab therapy for Alzheimer's disease in the Intermountain West. Alzheimer's & dementia (Amsterdam, Netherlands), 18(1), e70251.
Book Chapter
- Frost NA, MacGillavry HD, Lu HE, Blanpied TA (2014). Live-cell PALM of intracellular proteins in neurons. In Nägerl U, Triller A (Eds.), Nanoscale Imaging of Synapses. Neuromethods (84, pp. 93-123). New York, NY: Humana Press.