Paul S. Bernstein,
MD, PhD
Languages Spoken: English
Paul S. Bernstein, MD, PhD, divides his time between basic science retina research and a clinical practice devoted to medical and surgical treatment of diseases of the retina at the John A. Moran Eye Center at the University of Utah, where he has been a faculty member since 1995. He holds the Val A. and Edith D. Green Presidential Endowed Chair in Ophthalmology and Visual Sciences and is Moran’s Director of Clinical Research and Associate Director of Research. He has adjunct appointments in the University of Utah Department of Pharmacology and Toxicology, Department of Neurobiology and Anatomy, and Division of Neurosciences.
His clinical expertise includes age-related macular degeneration with special emphasis on the role of nutrition and environment in its treatment and prevention, inherited retinal and macular dystrophies, and surgical treatment of vitreoretinal disorders such as diabetic retinopathy and retinal detachments.
Dr. Bernstein did his undergraduate, MD, and PhD training at Harvard University. Highlights of his training at Harvard included a summa cum laude undergraduate degree in chemistry and a PhD thesis entitled “Biochemistry and Pharmacology of Rhodopsin Regeneration in the Vertebrate Eye” with Dr. Robert Rando of the Department of Pharmacology. His medical degree was from the Division of Health Sciences and Technology, a special joint program between Harvard Medical School and the Massachusetts Institute of Technology. After completing 12 years at Harvard, he moved to UCLA where he did a post-doctoral fellowship with Dr. Dean Bok in retinal cell biology and a residency in Ophthalmology at the Jules Stein Eye Institute. He then returned to Harvard for two more years for a fellowship in vitreoretinal research and surgery at the Massachusetts Eye and Ear Infirmary.
Dr. Bernstein has authored over 200 peer-reviewed research articles and reviews as well as over a dozen book chapters and has served as a reviewer for numerous journals, foundations, and institutes. His lab research interests include biochemistry and biophysics of nutritional interventions against inherited and acquired ocular disorders and the genetics and imaging of macular telangiectasia type 2 (MacTel)—a notoriously difficult-to-diagnose hereditary disease that causes central vision loss. He is among the first researchers worldwide to test the early diagnostic capabilities of fluorescence lifetime imaging ophthalmoscopy, a new non-invasive retinal imaging technique known as FLIO.
He has received numerous awards, including the 2020 Mildred Weisenfeld Award from the Association for Research in Vision and Ophthalmology; the Macula Society’s 2019 W. Richard Green Lecture in honor of work that has helped explain the pathogenesis of retinal diseases; and the American Academy of Ophthalmology’s 2016 Outstanding Humanitarian Service Award.
Dr. Bernstein is also dedicated to bringing modern vitreoretinal services to the developing world in a sustainable manner. Currently, access to retinal care is extremely limited in many parts of the world, and Dr. Bernstein provides hands-on specialty training to help expand the availability and quality of care. Dr. Bernstein has worked with Moran’s Global Outreach Division and the Himalayan Cataract Project to train aspiring retina specialists from Nepal, Ghana, Ethiopia, and Bhutan.
Specialties
Board Certification and Academic Information
| Academic Departments | Ophthalmology/Visual Sciences
-
Professor Neurobiology - Adjunct Professor Pharmacology and Toxicology - Adjunct Professor |
| Board Certification | American Board of Ophthalmology National Board of Medical Examiners |
Patient Rating
The Patient Rating score is an average of all responses to care provider related questions on our nationally-recognized Press Ganey Patient Satisfaction Survey.
Responses are measured on a scale of 1 to 5 with 5 being the best score.
Likelihood of recommending care provider
4.7/ 5
Care provider's explanation of condition/problem
4.7/ 5
Care provider's effort to include me in decisions
4.6/ 5
Wait time at clinic
4.2/ 5
Care provider's concern for questions & worries
4.6/ 5
Patient Comments
Patient comments are gathered from our Press Ganey Patient Satisfaction Survery and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
UofU Patient
May 19, 2022
MORAN EYE CENTER
I have visited the clinic twice as a patient, largely because of the recommendations of referring physicians and Dr. Bernstein's reputation for clinical excellence in AMD. I recognize the research and training-related aspects of his practice. However, upon each visit I have found the time spent with physician "fellows" to be entirely redundant and non-productive. During my most recent visit, the physician fellow examined images and my eyes, then spent the rest of her time with me typing in the EMR. Also, someone interrupted her and she left the examination room for several minutes while returning without apology. She resumed her typing. When she finished using the computer and finally made eye contact with me, I told the physician fellow of my hearing loss impairment and requested that she speak loudly and clearly to me. She did so momentarily, then resumed looking at the computer and pointing out certain clinical results in a soft voice, which, when spoken through a mask, were unintelligible to me. I repeated my request and clearly stated my desired results for this visit. From my perspective, the fellow brushed them aside and drove hurriedly toward her own objectives. Impersonal. Hurried. Non-compassionate. Unhelpful to me as a patient in terms of a treatment plan for a disease with no cure. As a longtime hospital CEO, I have hired and evaluated many physicians. In my view, this fellow as well as the one involved in my first visit will not be successful in private practice if they treat patients as I was treated. If the training regimen for such physician fellows orients them solely toward science, checklists, and labor productivity with little or no regard to patient satisfaction, compassion, and sincere caring, then the related future of medicine is darkened. When Dr. Bernstein finally came to the examination room, though seemingly a bit bored with yet another patient, he provided better information and paid more attention to me, but offered very little in terms of how continuing to use his clinic would benefit me. He spent no time to become acquainted with me, my lifestyle, or future plans. Near the end of our encounter, I said, in large part due to the above-described frustrations, to Dr. Bernstein that, "I didn't want to go blind." He responded with the perhaps the most valuable takeaway for me from the entire 3+ hour experience by saying something like, "We are here to help you avoid that."
UofU Patient
May 19, 2022
MORAN EYE CENTER
My scores above are referring to a Dr. Bernstein, he had terrible bedside manner. He said very little to me, I was nervous about my appt and his first comment to me was rude. Later on I got to see a Dr. Patel who was amazing and kind and compassionate.I can't say enough good about her.
UofU Patient
April 25, 2022
MORAN EYE CENTER
This was a preliminary check-in for complications as part of a larger illness. As such, discussions of treatment were minimal, as the larger disease's treatment is ongoing. What discussion was had was more than adequate for this visit.
UofU Patient
April 23, 2022
MORAN EYE CENTER
I think I have expressed I am unhappy with my experience
UofU Patient
April 21, 2022
MORAN EYE CENTER
Couldn't get any better!
UofU Patient
April 21, 2022
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Very positive!
UofU Patient
April 18, 2022
MORAN EYE CENTER
Have already done that.
UofU Patient
April 11, 2022
MORAN EYE CENTER
I have been under the care of Dr Bernstein for over 11 years. He is the very best and I trust him completely.
UofU Patient
March 30, 2022
MORAN EYE CENTER
Dr. Bernstein is brilliant and assuredly the best in his specialty. He described all options and procedures most clearly.
UofU Patient
March 27, 2022
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Dr. Bernstein is extremely knowledgeable, just the kind of doctor you want working on your eyes!
UofU Patient
March 20, 2022
MORAN EYE CENTER
I have referred several of my Friends to the Clinic over the years!
UofU Patient
March 14, 2022
MORAN EYE CENTER
They were all very kind
UofU Patient
March 13, 2022
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Dr Bernstein was very informative. He is the best!
UofU Patient
March 07, 2022
MORAN EYE CENTER
No as good as previous visits. Doctor Bernstein prescribed in office cryo-procedure and delegated it to resident. Resident's name not listed in Mychart after visit notes. Doctor didn't follow up - I was hoping to ask questions. After procedure, resident immediately went to find doctor to have him check work. She never came back so I could ask her questions either.
UofU Patient
March 03, 2022
MORAN EYE CENTER
Terrible experience.
UofU Patient
February 27, 2022
MORAN EYE CENTER
The medical staff was extremely concerned with my understanding of the purpose and scope of my treatment. Superior professional team!
UofU Patient
February 22, 2022
MORAN EYE CENTER
Dr Bernstein if very knowledgeable but seemed to be in more of a hurry. There was more pain with the injection this time as if they didn't give enough topical anesthetic and/or they were in a hurry.
UofU Patient
February 16, 2022
MORAN EYE CENTER
The professionalism is superb!
UofU Patient
January 29, 2022
MORAN EYE CENTER
Dr. Bernstein has always been excellent. My rating being very good is not given lightly. It is truly the way it has been.
UofU Patient
January 26, 2022
MORAN EYE CENTER
I have booklets made up and when someone needs help with there eye situations l give them that and then they know what to do and follow throug!
UofU Patient
January 26, 2022
MORAN EYE CENTER
Dr Bernstein is awesome. The best there is.
UofU Patient
January 18, 2022
MORAN EYE CENTER
Always good
UofU Patient
January 15, 2022
MORAN EYE CENTER
This is my second visit with Dr. Bernstein. He seems very short with me and makes me feel like a burden. He's not patient during exam.
UofU Patient
January 14, 2022
MORAN EYE CENTER
Very knowledgeable and caring. Great personality. Impressive.
UofU Patient
January 13, 2022
MORAN EYE CENTER
Tech was great. Dr Bernstein is always good.
UofU Patient
January 01, 2022
MORAN EYE CENTER
Dr Bernstein is very good and knowledgeable. However, we had to ask him to discuss the results of the retinal ultrasound photos that were taken just prior to being seen. We got the impression he was about to leave without discussing these.
UofU Patient
December 10, 2021
MORAN EYE CENTER
Very satisfied
UofU Patient
December 07, 2021
MORAN EYE CENTER
Grateful to have Dr. Bernstein as a doctor
UofU Patient
December 02, 2021
MORAN EYE CENTER
Best location for eye care.
UofU Patient
November 27, 2021
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Dr. Bernstein is doing everything he can to restore my vision. I am very pleased with his professionalism.
UofU Patient
November 16, 2021
MORAN EYE CENTER
I am always impressed with the care and concern at the center. Excellent people and care.
UofU Patient
November 15, 2021
MORAN EYE CENTER
I was being seen for macular degeneration but my cataract got most of the attention
UofU Patient
November 14, 2021
MORAN EYE CENTER
It seemed at the end of all the testing, not much feedback what the testing showed or compare to last year. I was Asked if I thought my eyesight was a little worse. I said yes---reading. Not much was suggested or discussed why. Referred me to a low vision clinic. Concerned about dry eye symptoms; referred me to a different eye specialist that is more Knowledgeable in dry eye syndrome. In fairness I have not read in My Chart yet the follow up report.
UofU Patient
November 08, 2021
MORAN EYE CENTER
World class, professional, kind
UofU Patient
November 06, 2021
MORAN EYE CENTER
I always keep on hand packets to hand out to anyone needing Quality Eye Care
UofU Patient
October 31, 2021
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Excellent care! I completely trust Dr Bernstein
UofU Patient
October 28, 2021
MORAN EYE CENTER
Dr. Bernstein is one of the best eye surgeons in the West. You are lucky to have him on staff.
UofU Patient
October 15, 2021
MORAN EYE CENTER
The doctor was professional and kind.
UofU Patient
October 12, 2021
MORAN EYE CENTER
Very helpful
UofU Patient
October 12, 2021
MORAN EYE CENTER
This was a regular checkup, not a new problem
UofU Patient
October 04, 2021
MORAN EYE CENTER
This was a check up from a previous year. I don't believe we have enough information yet to make any decisions. We scheduled an appt to get more information
UofU Patient
October 02, 2021
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Dr Bernstein is the best in his field! He cared for my husband for several years before he died. I feell blessed and confident in his thorough examination of my eyes.
UofU Patient
September 11, 2021
MORAN EYE CENTER
Dr Bernstein is the best!
UofU Patient
September 06, 2021
MORAN EYE CENTER
I always feel like I'm the only patient in the clinic. I never feel rushed, or that the question I asked was as vapid as it probably was.
UofU Patient
September 05, 2021
MORAN EYE CENTER
Professional and EXTREMELY KNOWLEDGEABLE!!! Could not have been more lucky to be seen by this physician
UofU Patient
September 05, 2021
MORAN EYE CENTER
I am so impressed with The Moran Eye Center, first class eye care.
UofU Patient
August 16, 2021
MORAN EYE CENTER
Dr. Bernstein is an excellent retinal specialist and Doctor. I am lucky to be one of his patients.
UofU Patient
August 16, 2021
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
I was somewhat nervous about having an injection into my eye. Dr. Bernstein and his staff reassured me that this procedure was routine and my level of discomfort would be minimal, and it was.
UofU Patient
August 11, 2021
MORAN EYE CENTER
There Iis Iinformation that I don't ask at the moment and I wasn't told that should have been address like I was doing well but they didn't informed me of how to handle my activities in order to protect my vision. I work in packing items up to 49 lbs and I call to be informed about the weight I could carry and I was told not more than 20. Wow... Aam glad I call before started to work.
UofU Patient
August 09, 2021
MORAN EYE CENTER
I am impressed with the changes made at this particular clinic. I used to be a UofU patient for everything but I had to change my family doctor because of the lack of interest in me as a patient. But kudos for you guys with this improvement as a facility and as faculty at this Moran Eye Center.
Paul S. Bernstein, MD, PhD, divides his time between basic science retina research and a clinical practice devoted to medical and surgical treatment of diseases of the retina at the John A. Moran Eye Center at the University of Utah, where he has been a faculty member since 1995. He holds the Val A. and Edith D. Green Presidential Endowed Chair in Ophthalmology and Visual Sciences and is Moran’s Director of Clinical Research and Associate Director of Research. He has adjunct appointments in the University of Utah Department of Pharmacology and Toxicology, Department of Neurobiology and Anatomy, and Division of Neurosciences.
His clinical expertise includes age-related macular degeneration with special emphasis on the role of nutrition and environment in its treatment and prevention, inherited retinal and macular dystrophies, and surgical treatment of vitreoretinal disorders such as diabetic retinopathy and retinal detachments.
Dr. Bernstein did his undergraduate, MD, and PhD training at Harvard University. Highlights of his training at Harvard included a summa cum laude undergraduate degree in chemistry and a PhD thesis entitled “Biochemistry and Pharmacology of Rhodopsin Regeneration in the Vertebrate Eye” with Dr. Robert Rando of the Department of Pharmacology. His medical degree was from the Division of Health Sciences and Technology, a special joint program between Harvard Medical School and the Massachusetts Institute of Technology. After completing 12 years at Harvard, he moved to UCLA where he did a post-doctoral fellowship with Dr. Dean Bok in retinal cell biology and a residency in Ophthalmology at the Jules Stein Eye Institute. He then returned to Harvard for two more years for a fellowship in vitreoretinal research and surgery at the Massachusetts Eye and Ear Infirmary.
Dr. Bernstein has authored over 200 peer-reviewed research articles and reviews as well as over a dozen book chapters and has served as a reviewer for numerous journals, foundations, and institutes. His lab research interests include biochemistry and biophysics of nutritional interventions against inherited and acquired ocular disorders and the genetics and imaging of macular telangiectasia type 2 (MacTel)—a notoriously difficult-to-diagnose hereditary disease that causes central vision loss. He is among the first researchers worldwide to test the early diagnostic capabilities of fluorescence lifetime imaging ophthalmoscopy, a new non-invasive retinal imaging technique known as FLIO.
He has received numerous awards, including the 2020 Mildred Weisenfeld Award from the Association for Research in Vision and Ophthalmology; the Macula Society’s 2019 W. Richard Green Lecture in honor of work that has helped explain the pathogenesis of retinal diseases; and the American Academy of Ophthalmology’s 2016 Outstanding Humanitarian Service Award.
Dr. Bernstein is also dedicated to bringing modern vitreoretinal services to the developing world in a sustainable manner. Currently, access to retinal care is extremely limited in many parts of the world, and Dr. Bernstein provides hands-on specialty training to help expand the availability and quality of care. Dr. Bernstein has worked with Moran’s Global Outreach Division and the Himalayan Cataract Project to train aspiring retina specialists from Nepal, Ghana, Ethiopia, and Bhutan.
Academic Locations
Board Certification and Academic Information
| Academic Departments | Ophthalmology/Visual Sciences
-
Professor Neurobiology - Adjunct Professor Pharmacology and Toxicology - Adjunct Professor |
| Board Certification | American Board of Ophthalmology National Board of Medical Examiners |
Education History
| Fellowship | Massachusetts Eye and Ear Infirmary Vitreoretinal Surgery Fellow, 1995 |
| Residency | UCLA Medical Center, Jules Stein Eye Institute Ophthalmology Resident, 1993 |
| Postdoctoral Fellowship | UCLA Medical Center, Jules Stein Eye Institute Cell Biology Postdoctoral Fellow, 1990 |
| Internship | New England Deaconess Hospital Internal Medicine Intern, 1989 |
| Doctoral Training | Harvard University Pharmacology Ph.D., 1988 |
| Professional Medical | Harvard Medical School/MIT - Division of Health Sciences & Technology Medicine M.D., 1988 |
| Undergraduate | Harvard University Chemistry, summa cum laude A.B., 1981 |
Selected Publications - Journal Articles
Journal Article
- Cheng V, Rallabandi R, Gorusupudi A, Lucas S, Rognon G, Bernstein PS, Rainier JD, Conboy JC (2022). Influence of very-long-chain polyunsaturated fatty acids on membrane structure and dynamics. Biophys J, 121(14), 2730-2741.
- Rai BB, Morley MG, Bernstein PS, Maddess T (2022). Severity of age-related macular degeneration at first presentation in Bhutan: a 3-year national study. BMC Ophthalmol, 22(1), 298.
- Bernstein PS (2022). Nourishing Better Vision: The ARVO 2021 Mildred Weisenfeld Award Lecture. Invest Ophthalmol Vis Sci, 63(3), 13.
- Li B, Vachali P, Chang FY, Gorusupudi A, Arunkumar R, Shi L, Rognon GT, Frederick JM, Bernstein PS (2021). HDL is the primary transporter for carotenoids from liver to retinal pigment epithelium in transgenic ApoA-I-/-/Bco2-/- mice. Arch Biochem Biophys, 716, 109111.
- Takayanagi Y, Obana A, Muto S, Asaoka R, Tanito M, Ermakov IV, Bernstein PS, Gellermann W (2021). Relationships between Skin Carotenoid Levels and Metabolic Syndrome. Antioxidants (Basel), 11(1).
- Obana A, Gohto Y, Asaoka R, Gellermann W, Bernstein PS (2021). Lutein and Zeaxanthin Distribution in the Healthy Macula and Its Association with Various Demographic Factors Examined in Pseudophakic Eyes. Antioxidants (Basel), 10(12).
- Iannaccone A, Brewer CC, Cheng P, Duncan JL, Maguire MG, Audo I, Ayala AR, Bernstein PS, Bidelman GM, Cheetham JK, Doty RL, Durham TA, Hufnagel RB, Myers MH, Stingl K, Zein WM, Foundation Fighting Blindness Consortium Investigator Group (2021). Auditory and olfactory findings in patients with USH2A-related retinal degeneration-Findings at baseline from the rate of progression in USH2A-related retinal degeneration natural history study (RUSH2A). Am J Med Genet A, 185, 3717-3727.
- Sauer L, Vitale AS, Modersitzki NK, Bernstein PS (2021). LONGITUDINAL FLUORESCENCE LIFETIME IMAGING OPHTHALMOSCOPY ANALYSIS IN PATIENTS WITH MACULAR TELANGIECTASIA TYPE 2 (MacTel). Retina, 41(7), 1416-1427.
- Wade A, Rallabandi R, Lucas S, Oberg C, Gorusupudi A, Bernstein PS, Rainier JD (2021). The synthesis of the very long chain polyunsaturated fatty acid (VLC-PUFA) 32:6 n-3. Org Biomol Chem, 19(25), 5563-5566.
- Arunkumar R, Gorusupudi A, Li B, Blount JD, Nwagbo U, Kim HJ, Sparrow JR, Bernstein PS (2021). Lutein and zeaxanthin reduce A2E and iso-A2E levels and improve visual performance in Abca4-/-/Bco2-/- double knockout mice. Exp Eye Res, 209, 108680.
- Goerdt L, Sauer L, Vitale AS, Modersitzki NK, Fleckenstein M, Bernstein PS (2021). Comparing Fluorescence Lifetime Imaging Ophthalmoscopy in Atrophic Areas of Retinal Diseases. Transl Vis Sci Technol, 10(7), 11.
- da Palma MM, Igelman AD, Ku C, Burr A, You JY, Place EM, Wang NK, Oh JK, Branham KE, Zhang X, Ahn J, Gorin MB, Lam BL, Ronquillo CC, Bernstein PS, Nagiel A, Huckfeldt R, Cabrera MT, Kelly JP, Bakall B, Iannaccone A, Hufnagel RB, Zein WM, Koenekoop RK, Birch DG, Yang P, Fahim AT, Pennesi ME (2021). Characterization of the Spectrum of Ophthalmic Changes in Patients With Alagille Syndrome. Invest Ophthalmol Vis Sci, 62(7), 27.
- Addo EK, Gorusupudi A, Allman S, Bernstein PS (2021). The Lutein and Zeaxanthin in Pregnancy (L-ZIP) study-carotenoid supplementation during pregnancy: ocular and systemic effects-study protocol for a randomized controlled trial. Trials, 22(1), 300.
- Gorusupudi A, Rallabandi R, Li B, Arunkumar R, Blount JD, Rognon GT, Chang FY, Wade A, Lucas S, Conboy JC, Rainier JD, Bernstein PS (2021). Retinal bioavailability and functional effects of a synthetic very-long-chain polyunsaturated fatty acid in mice. Proc Natl Acad Sci U S A, 118(6).
- Bernstein PS, Arunkumar R (2021). The emerging roles of the macular pigment carotenoids throughout the lifespan and in prenatal supplementation. J Lipid Res, 62, 100038.
- Bernstein PS, Ranganathan A (2021). The emerging roles of the macular pigment carotenoids throughout the lifespan and in prenatal supplementation. J Lipid Res, 100038.
- Sauer L, Vitale AS, Modersitzki NK, Bernstein PS (2020). Fluorescence lifetime imaging ophthalmoscopy: autofluorescence imaging and beyond. Eye (Lond), 35(1), 93-109.
- Lakk M, Hoffmann GF, Gorusupudi A, Enyong E, Lin A, Bernstein PS, Toft-Bertelsen T, MacAulay N, Elliott MH, Kriaj D (2021). Membrane cholesterol regulates TRPV4 function, cytoskeletal expression, and the cellular response to tension. J Lipid Res, 62, 100145.
- Hicks PM, Haaland B, Feehan M, Crandall AS, Pettey JH, Nuttall E, Self W, Hartnett ME, Bernstein P, Vitale A, Shakoor A, Shulman JP, Sieminski SF, Kim I, Owen LA, Murtaugh MA, Noyes A, DeAngelis MM (2020). Systemic Disease and Ocular Comorbidity Analysis of Geographically Isolated Federally Recognized American Indian Tribes of the Intermountain West. J Clin Med, 9(11).
- Arunkumar R, Gorusupudi A, Bernstein PS (2020). The macular carotenoids: A biochemical overview. Biochim Biophys Acta Mol Cell Biol Lipids, 1865(11), 158617.
- Rai BB, Morley MG, Zangmo P, Tshering T, Khatiwara AN, Bernstein PS, Maddess T (2020). Retinal laser services in Bhutan: a 3-year national survey. BMC Ophthalmol, 20(1), 404.
- Vitale AS, Sauer L, Modersitzki NK, Bernstein PS (2020). Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO) in Patients with Choroideremia. Transl Vis Sci Technol, 9(10), 33.
- Rai BB, Morley MG, Zangmo P, Tschering T, Khatiwara AN, Bernstein PS, Maddes T (2020). Surgical Management of VR Patients in Bhutan.
- Zucker CL, Bernstein PS, Schalek RL, Lichtman JW, Dowling JE (2020). A connectomics approach to understanding a retinal disease. Proc Natl Acad Sci U S A, 117(31), 18780-18787.
- Sauer L, Vitale AS, Milliken CM, Modersitzki NK, Blount JD, Bernstein PS (2020). Autofluorescence Lifetimes Measured with Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO) Are Affected by Age, but Not by Pigmentation or Gender. Transl Vis Sci Technol, 9(9), 2.
- Obana A, Gohto Y, Nakazawa R, Moriyama T, Gellermann W, Bernstein PS (2020). Effect of an antioxidant supplement containing high dose lutein and zeaxanthin on macular pigment and skin carotenoid levels. Sci Rep, 10(1), 10262.
- Zhai Y, Xu M, Dimopoulos IS, Birch DG, Bernstein PS, Holt J, Kirn D, Francis P, MacDonald IM (2020). Quantification of RPE Changes in Choroideremia Using a Photoshop-Based Method. Transl Vis Sci Technol, 9(7), 21.
- Li B, George EW, Rognon GT, Gorusupudi A, Ranganathan A, Chang FY, Shi L, Frederick JM, Bernstein PS (2020). Imaging lutein and zeaxanthin in the human retina with confocal resonance Raman microscopy. Proc Natl Acad Sci U S A, 117(22), 12352-12358.
- Sauer L, Vitale AS, Andersen KM, Hart B, Bernstein PS (2019). FLUORESCENCE LIFETIME IMAGING OPHTHALMOSCOPY (FLIO) PATTERNS IN CLINICALLY UNAFFECTED CHILDREN OF MACULAR TELANGIECTASIA TYPE 2 (MACTEL) PATIENTS. Retina, 40(4), 695-704.
- Obana A, Gohto Y, Sasano H, Gellermann W, Sharifzadeh M, Seto T, Bernstein PS (2020). Spatial distribution of macular pigment estimated by autofluorescence imaging in elderly Japanese individuals. Jpn J Ophthalmol, 64(2), 160-170.
- Rai BB, Morley MG, Bernstein PS, Maddess T (2020). Pattern of vitreo-retinal diseases at the national referral hospital in Bhutan: a retrospective, hospital-based study. BMC Ophthalmol, 20(1), 51.
- Green-Gomez M, Bernstein PS, Curcio CA, Moran R, Roche W, Nolan JM (2019). Standardizing the Assessment of Macular Pigment Using a Dual-Wavelength Autofluorescence Technique. Transl Vis Sci Technol, 8(6), 41.
- Bernstein PS (2019). Does Dark Chocolate Enhance Visual Function? JAMA Ophthalmol, 137(12), 1380.
- Gantner ML, Eade K, Wallace M, Handzlik MK, Fallon R, Trombley J, Bonelli R, Giles S, Harkins-Perry S, Heeren TFC, Sauer L, Ideguchi Y, Baldini M, Scheppke L, Dorrell MI, Kitano M, Hart BJ, Cai C, Nagasaki T, Badur MG, Okada M, Woods SM, Egan C, Gillies M, Guymer R, Eichler F, Bahlo M, Fruttiger M, Allikmets R, Bernstein PS, Metallo CM, Friedlander M (2019). Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy. N Engl J Med, 381(15), 1422-1433.
- Sauer L, Calvo CM, Vitale AS, Henrie N, Milliken CM, Bernstein PS (2019). Imaging of Hydroxychloroquine Toxicity with Fluorescence Lifetime Imaging Ophthalmoscopy. Ophthalmol Retina, 3(10), 814-825.
- Strauss RW, Kong X, Ho A, Jha A, West S, Ip M, Bernstein PS, Birch DG, Cideciyan AV, Michaelides M, Sahel JA, Sunness JS, Traboulsi EI, Zrenner E, Pitetta S, Jenkins D, Hariri AH, Sadda S, Scholl HPN, ProgStar Study Group (2019). Progression of Stargardt Disease as Determined by Fundus Autofluorescence Over a 12-Month Period: ProgStar Report No. 11. JAMA Ophthalmol, 137(10), 1134-1145.
- Ronquillo CC, Sauer L, Morgan D, Heckzo JB, Creel DJ, Mamalis N, DeAngelis MM, Hagemann GS, Bernstein PS (2019). ABSENCE OF MACULAR DEGENERATION IN A PATIENT WITH ACERULOPLASMINEMIA. Retina, 39(9), 1824-1828.
- Sauer L, Li B, Bernstein PS (2019). Ocular Carotenoid Status in Health and Disease. Annu Rev Nutr, 39, 95-120.
- Gorusupudi A, Chang FY, Nelson K, Hageman GS, Bernstein PS (2019). n-3 PUFA Supplementation Alters Retinal Very-Long-Chain-PUFA Levels and Ratios in Diabetic Animal Models. Mol Nutr Food Res, 63(15), e1801058.
- Sauer L, Komanski CB, Vitale AS, Hansen ED, Bernstein PS (2019). Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO) in Eyes With Pigment Epithelial Detachments Due to Age-Related Macular Degeneration. Invest Ophthalmol Vis Sci, 60(8), 3054-3063.
- Obana A, Gohto Y, Gellermann W, Ermakov IV, Sasano H, Seto T, Bernstein PS (2019). Skin Carotenoid Index in a large Japanese population sample. Sci Rep, 9(1), 9318.
- Fujinami K, Strauss RW, Chiang JP, Audo IS, Bernstein PS, Birch DG, Bomotti SM, Cideciyan AV, Ervin AM, Marino MJ, Sahel JA, Mohand-Said S, Sunness JS, Traboulsi EI, West S, Wojciechowski R, Zrenner E, Michaelides M, Scholl HPN, ProgStar Study Group, ProgStar Study Group (2018). Detailed genetic characteristics of an international large cohort of patients with Stargardt disease: ProgStar study report 8. Br J Ophthalmol, 103(3), 390-397.
- Hicks PM, Melendez SAC, Vitale A, Self W, Hartnett ME, Bernstein P, Morgan DJ, Feehan M, Shakoor A, Kim I, Owen LA, DeAngelis MM (2019). Genetic Epidemiologic Analysis of Hypertensive Retinopathy in an Underrepresented and Rare Federally Recognized Native American Population of the Intermountain West. J Community Med Public Health, 3(1).
- Trujillo Tanner C, Caserta MS, Kleinschmidt JJ, Clayton MS, Bernstein PS, Guo JW (2018). Conducting Research With Older Adults With Vision Impairment: Lessons Learned and Recommended Best Practices. Gerontol Geriatr Med, 4, 2333721418812624.
- Ronquillo CC, Wegner K, Calvo CM, Bernstein PS (2018). Genetic Penetrance of Macular Telangiectasia Type 2. JAMA Ophthalmol, 136(10), 1158-1163.
- Sauer L, Andersen KM, Dysli C, Zinkernagel MS, Bernstein PS, Hammer M (2018). Review of clinical approaches in fluorescence lifetime imaging ophthalmoscopy. J Biomed Opt, 23(9), 1-20.
- Cheng JL, Farnsworth K, Bernstein PS (2018). Choroideremia in a Woman With Turner Syndrome. JAMA Ophthalmol, 136(9), 1076-1078.
- Li B, Rognon GT, Mattinson T, Vachali PP, Gorusupudi A, Chang FY, Ranganathan A, Nelson K, George EW, Frederick JM, Bernstein PS (2018). Supplementation with macular carotenoids improves visual performance of transgenic mice. Arch Biochem Biophys, 649, 22-28.
- Andersen KM, Sauer L, Gensure RH, Hammer M, Bernstein PS (2018). Characterization of Retinitis Pigmentosa Using Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO). Transl Vis Sci Technol, 7(3), 20.
- Sauer L, Andersen KM, Li B, Gensure RH, Hammer M, Bernstein PS (2018). Fluorescence Lifetime Imaging Ophthalmoscopy (FLIO) of Macular Pigment. Invest Ophthalmol Vis Sci, 59(7), 3094-3103.
- Obana A, Gohto Y, Sasano H, Gellermann W, Sharifzadeh M, Seto T, Bernstein PS (2018). Grade of Cataract and Its Influence on Measurement of Macular Pigment Optical Density Using Autofluorescence Imaging. Invest Ophthalmol Vis Sci, 59(7), 3011-3019.
- Arunkumar R, Calvo CM, Conrady CD, Bernstein PS (2018). What do we know about the macular pigment in AMD: the past, the present, and the future. Eye (Lond), 32(5), 992-1004.
- Bhosale P, Zhao DY, Bernstein PS (2007). HPLC measurement of ocular carotenoid levels in human donor eyes in the lutein supplementation era. Invest Ophthalmol Vis Sci, 48(2), 543-9.
- Bhosale P, Bernstein PS (2005). Microbial xanthophylls. Appl Microbiol Biotechnol, 68(4), 445-55.
- Bernstein PS, Gellermann W (2002). Measurement of carotenoids in the living primate eye using resonance Raman spectroscopy. Methods Mol Biol, 196, 321-9.
Editorial
Letter
Other
Patent
- Gellermann W, McClane RW, Bernstein PS (2007). Optical method and apparatus for determining status of agricultural products. U.S. Patent No. 10.271.914. Washington, D.C.:U.S. Patent and Trademark Office.
- McClane RW, Gellermann W, Bernstein PS (2006). Method and apparatus for Raman imaging of macular pigments. U.S. Patent No. 7.039.452. Washington, D.C.:U.S. Patent and Trademark Office.
- Gellermann W, McClane RW, Katz NB, Bernstein PS (2001). Method and apparatus for noninvasive measurement of carotenoids and related chemical substances in biological tissue. U.S. Patent No. 6,205,354. Washington, D.C.:U.S. Patent and Trademark Office.
- Bernstein PS, Gellermann W, McClane RW (1999). Method and system for measurement of macular carotenoid levels. U.S. Patent No. 5,873,831. Washington, D.C.:U.S. Patent and Trademark Office.
Global Impact
Selected Provider Publications
Journal Article
Hicks PM, Haaland B, Feehan M, Crandall AS, Pettey JH, Nuttall E, Self W, Hartnett ME, Bernstein P, Vitale A, Shakoor A, Shulman JP, Sieminski SF, Kim I, Owen LA, Murtaugh MA, Noyes A, DeAngelis MM (2020). Systemic Disease and Ocular Comorbidity Analysis of Geographically Isolated Federally Recognized American Indian Tribes of the Intermountain West. J Clin Med, 9(11).
Global Impact: Native American Nations.Rai BB, Morley MG, Zangmo P, Tshering T, Khatiwara AN, Bernstein PS, Maddess T (2020). Retinal laser services in Bhutan: a 3-year national survey. BMC Ophthalmol, 20(1), 404.
Global Impact: Bhutan.Rai BB, Morley MG, Zangmo P, Tschering T, Khatiwara AN, Bernstein PS, Maddes T (2020). Surgical Management of VR Patients in Bhutan.
Global Impact: Bhutan.Obana A, Gohto Y, Sasano H, Gellermann W, Sharifzadeh M, Seto T, Bernstein PS (2020). Spatial distribution of macular pigment estimated by autofluorescence imaging in elderly Japanese individuals. Jpn J Ophthalmol, 64(2), 160-170.
Global Impact: Japan.Rai BB, Morley MG, Bernstein PS, Maddess T (2020). Pattern of vitreo-retinal diseases at the national referral hospital in Bhutan: a retrospective, hospital-based study. BMC Ophthalmol, 20(1), 51.
Global Impact: Bhutan.
News Articles
The Scope & Other Podcasts
- Meet Paul S. Bernstein, MD, PhD
- “New Frontiers in the Treatment of Macular and Retinal Disease: Nutrition, Stem Cells, Gene Therapy, and Beyond.”
- Update on Aging Macular Degeneration Treatments, Research
- What You Need to Know About Aging Macular Degeneration
- AREDS II Study Overview and Results on AMD Nutrition
- An Unexpected Pit Stop: teen eye injury