Nicole L. Pershing
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Nicole L. Pershing, MD, PHD

Languages spoken: English

  • Dr. Pershing is an Assistant Professor of Pediatrics in the Division of Pediatric Infectious Diseases at the University of Utah. Dr. Pershing completed her Doctoral and Medical degrees at Duke University School of Medicine. She then completed her residency training in Pediatrics and fellowship training in Pediatric Infectious Diseases at the University of Utah and Primary Children’s Hospital.


    Dr. Pershing’s clinical interests include treatment and prevention of general infectious diseases, with a special interest in serious bacterial infections in children. Dr. Pershing’s research interests include investigation of bacterial, viral, and patient factors that contribute to these severe bacterial infections. Her current research focuses on genetic elements present in bacteria that are associated with severe infections, and the impact of viruses that infect bacteria, called bacteriophages, on bacteria present in the gut microbial community that cause human disease.

    Specialties

    Board Certification

    American Board of Pediatrics (Pediatrics)
    American Board of Pediatrics (Sub: Pediatric Infectious Diseases)

  • Dr. Pershing is an Assistant Professor of Pediatrics in the Division of Pediatric Infectious Diseases at the University of Utah. Dr. Pershing completed her Doctoral and Medical degrees at Duke University School of Medicine. She then completed her residency training in Pediatrics and fellowship training in Pediatric Infectious Diseases at the University of Utah and Primary Children’s Hospital.


    Dr. Pershing’s clinical interests include treatment and prevention of general infectious diseases, with a special interest in serious bacterial infections in children. Dr. Pershing’s research interests include investigation of bacterial, viral, and patient factors that contribute to these severe bacterial infections. Her current research focuses on genetic elements present in bacteria that are associated with severe infections, and the impact of viruses that infect bacteria, called bacteriophages, on bacteria present in the gut microbial community that cause human disease.

    Board Certification and Academic Information

    Academic Departments Pediatrics -Assistant Professor
    Academic Divisions Infectious Diseases
    Board Certification
    American Board of Pediatrics (Pediatrics)
    American Board of Pediatrics (Sub: Pediatric Infectious Diseases)

    Selected Publications

    Journal Article

    1. Cadotte N, Moore H, Stone BL, Pershing NL, Ampofo K, Ou Z, Pavia AT, Blaschke AJ, Flaherty B, Crandall H (2023). Prevalence of and Risks for Bacterial Infections in Hospitalized Children With Bronchiolitis. Hosp Pediatr, 14(8), 603-611. (Read full article)
    2. Belman S, Lefrancq N, Nzenze S, Downs S, du Plessis M, Lo SW, Global Pneumococcal Sequencing Consortium, McGee L, Madhi SA, von Gottberg A, Bentley SD, Salje H (2024). Geographical migration and fitness dynamics of Streptococcus pneumoniae. Nature, 631(8020), 386-392. (Read full article)
    3. Le Roux, Pershing NLK, Kaltenbrun E, Newman NJ, Everitt JI, Baldelli E, Pierobon M, Petricoin EF, Counter CM (2022). Genetically manipulating endogenous Kras levels and oncogenic mutations in vivo influences tissue patterning of murine tumorigenesis. Elife, 11. (Read full article)
    4. Gladstone RA, Lo SW, Goater R, Yeats C, Taylor B, Hadfield J, Lees JA, Croucher NJ, van Tonder AJ, Bentley LJ, Quah FX, Blaschke AJ, Pershing NL, Byington CL, Balaji V, Hryniewicz W, Sigauque B, Ravikumar KL, Almeida SCG, Ochoa TJ, Ho PL, du Plessis M, Ndlangisa KM, Cornick JE, Kwambana-Adams B, Benisty R, Nzenze SA, Madhi SA, Hawkins PA, Pollard AJ, Everett DB, Antonio M, Dagan R, Klugman KP, von Gottberg A, Metcalf BJ, Li Y, Beall BW, McGee L, Breiman RF, Aanensen DM, Bentley SD, The Global Pneumococcal Sequencing Consortium (2020). Visualizing variation within Global Pneumococcal Sequence Clusters (GPSCs) and country population snapshots to contextualize pneumococcal isolates. Microb Genom, 6(5). (Read full article)
    5. Pershing NL, Yang CFJ, Xu M, Counter CM (2015). Treatment with the nitric oxide synthase inhibitor L-NAME provides a survival advantage in a mouse model of Kras mutation-positive, non-small cell lung cancer. Oncotarget, 7(27), 42385-42392. (Read full article)
    6. Pershing NL, Lampson BL, Belsky JA, Kaltenbrun E, MacAlpine DM, Counter CM (2014). Rare codons capacitate Kras-driven de novo tumorigenesis. J Clin Invest, 125(1), 222-33. (Read full article)
    7. Lampson BL, Pershing NL, Prinz JA, Lacsina JR, Marzluff WF, Nicchitta CV, MacAlpine DM, Counter CM (2012). Rare codons regulate KRas oncogenesis. Curr Biol, 23(1), 70-5. (Read full article)
    8. Kashatus DF, Lim KH, Brady DC, Pershing NL, Cox AD, Counter CM (2011). RALA and RALBP1 regulate mitochondrial fission at mitosis. Nat Cell Biol, 13(9), 1108-15. (Read full article)

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