Timothy M. Hanley

Timothy M. Hanley, MD, PhD

Languages spoken: English

  • Dr. Hanley is a pathology instructor at the University of Utah School of Medicine. He received his MD and a PhD in microbiology from Boston University School of Medicine and is certified by the American Board of Pathology in anatomic and clinical pathology, with eligibility for subspecialty certification in hematology. His research interests include HIV-1 infection of macrophages, the contribution of viral infections to lymphomagenesis, and the role of innate immune receptor signaling in adult and pediatric non-Hodgkin lymphomas. Dr. Hanley is a member the Society for Hematopathology, the College of American Pathologists, and the United States and Canadian Academy of Pathology.

    Specialties

    Board Certification

    American Board of Pathology (Anatomic)
    American Board of Pathology (Clinical Path)
    American Board of Pathology (Sub: Hematology)

  • Dr. Hanley is a pathology instructor at the University of Utah School of Medicine. He received his MD and a PhD in microbiology from Boston University School of Medicine and is certified by the American Board of Pathology in anatomic and clinical pathology, with eligibility for subspecialty certification in hematology. His research interests include HIV-1 infection of macrophages, the contribution of viral infections to lymphomagenesis, and the role of innate immune receptor signaling in adult and pediatric non-Hodgkin lymphomas. Dr. Hanley is a member the Society for Hematopathology, the College of American Pathologists, and the United States and Canadian Academy of Pathology.

    Board Certification and Academic Information

    Academic Departments Pathology -Primary
    Board Certification
    American Board of Pathology (Anatomic)
    American Board of Pathology (Clinical Path)
    American Board of Pathology (Sub: Hematology)

    Education history

    Postdoctoral Fellowship Hematopathology - University of Utah School of Medicine Postdoctoral Fellow
    Clinical Pathology - University of Utah School of Medicine Chief Resident
    Residency Anatomic and Clinical Pathology - University of Utah School of Medicine Resident
    Medicine, Microbiology - Boston University School of Medicine M.D., Ph.D.
    Undergraduate Government - Harvard University B.A.

    Selected Publications

    Journal Article

    1. Viglianti GA, Planelles V, Hanley TM (). Interactions with Commensal and Pathogenic Bacteria Induce HIV-1 Latency in Macrophages through Altered Transcription Factor Recruitment to the LTR. (Epub ahead of print) J Virol.
    2. Martins LJ, Szaniawski MA, Williams ESCP, Coiras M, Hanley TM, Planelles V (2022). HIV-1 Accessory Proteins Impart a Modest Interferon Response and Upregulate Cell Cycle-Related Genes in Macrophages. Pathogens, 11(2). (Read full article)
    3. Viglianti GA, Planelles V, Hanley TM (2021). Interactions with Commensal and Pathogenic Bacteria Induce HIV-1 Latency in Macrophages through Altered Transcription Factor Recruitment to the LTR. J Virol. (Read full article)
    4. Szaniawski MA, Spivak AM, Cox JE, Catrow JL, Hanley T, Williams ESCP, Tremblay MJ, Bosque A, Planelles V (2018). SAMHD1 Phosphorylation Coordinates the Anti-HIV-1 Response by Diverse Interferons and Tyrosine Kinase Inhibition. mBio, 9(3), e00819-18.
    5. Hanley T, Sowder AM, Palmer CA, Weiss RL (2016). Teaching Laboratory Management Principles and Practices Through Mentorship and Graduated Responsibility: The Assistant Medical Directorship. Acad Pathol, 3, 2374289516678972. (Read full article)
    6. Dickey LL, Duncan JK, Hanley TM, Fearns R (2015). Decapping protein 1 phosphorylation modulates IL-8 expression during respiratory syncytial virus infection. Virology, 481, 199-209. (Read full article)
    7. Hanley TM, Viglianti GA (2011). Nuclear receptor signaling inhibits HIV-1 replication in macrophages through multiple trans-repression mechanisms. J Virol, 85(20), 10834-50. (Read full article)
    8. Hanley TM, Blay Puryear W, Gummuluru S, Viglianti GA (2010). PPARgamma and LXR signaling inhibit dendritic cell-mediated HIV-1 capture and trans-infection. PLoS Pathog, 6, e1000981. (Read full article)
    9. Kiefer HL, Hanley TM, Marcello JE, Karthik AG, Viglianti GA (2004). Retinoic acid inhibition of chromatin remodeling at the human immunodeficiency virus type 1 promoter. Uncoupling of histone acetylation and chromatin remodeling. J Biol Chem, 279(42), 43604-13. (Read full article)
    10. Hanley TM, Kiefer HL, Schnitzler AC, Marcello JE, Viglianti GA (2004). Retinoid-dependent restriction of human immunodeficiency virus type 1 replication in monocytes/macrophages. J Virol, 78(6), 2819-30. (Read full article)
    11. Viglianti GA, Lau CM, Hanley TM, Miko BA, Shlomchik MJ, Marshak-Rothstein A (2003). Activation of autoreactive B cells by CpG dsDNA. Immunity, 19(6), 837-47. (Read full article)
    12. Gallina A, Hanley TM, Mandel R, Trahey M, Broder CC, Viglianti GA, Ryser HJ (2002). Inhibitors of protein-disulfide isomerase prevent cleavage of disulfide bonds in receptor-bound glycoprotein 120 and prevent HIV-1 entry. J Biol Chem, 277(52), 50579-88. (Read full article)
    13. Brown XQ, Hanley TM, Viglianti GA (2002). Interleukin 1 beta and interleukin 6 potentiate retinoic acid-mediated repression of human immunodeficiency virus type 1 replication in macrophages. AIDS Res Hum Retroviruses, 18(9), 649-56. (Read full article)

    Review

    1. Dickey LL, Hanley TM, Huffaker TB, Ramstead AG, OConnell RM, Lane TE (2017). MicroRNA 155 and viral-induced neuroinflammation. [Review]. J Neuroimmunol, 308, 17-24. (Read full article)

    Case Report

    1. Agarwal AM, Hanley TM (2020). Osteopetrosis in a six-month-old infant. J Hematop, 13, 193-196.

    Other

    1. Signorelli H, Hanley TM (2015). Considerations in Choosing Hemoglobin A1c Methods. Clinical Laboratory News: Bench Matters.

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