M. Mateo Paz Soldán,
MD, PhD
Languages Spoken: English
Dr. Paz Soldán is Assistant Professor in the Neuroimmunology Division of Neurology at the University of Utah. His clinical interests focus on multiple sclerosis (MS), neuromyelitis optica (NMO), and other inflammatory or demyelinating diseases of the central nervous system. His interests extend to autoimmune neurologic diseases -- those primarily affecting the nervous system, those occurring with rheumatologic disease, and those occurring in the setting of cancer (paraneoplastic). He also has interest in general clinical neurology.
Clinical Locations
Imaging and Neurosciences Center
801-585-7575
Board Certification and Academic Information
| Academic Departments | Neurology
-
Assistant Professor |
| Academic Divisions | Neuroimmunology |
| Board Certification | American Board of Psychiatry & Neurology (Neurology) |
Patient Rating
The Patient Rating score is an average of all responses to care provider related questions on our nationally-recognized Press Ganey Patient Satisfaction Survey.
Responses are measured on a scale of 1 to 5 with 5 being the best score.
Likelihood of recommending care provider
4.4/ 5
Care provider spoke using clear language
4.6/ 5
Care provider's explanation of condition/problem
4.5/ 5
My confidence in care provider
4.5/ 5
Care provider's effort to include me in decisions
4.5/ 5
Wait time at clinic
3.3/ 5
Time care provider spent with me
4.6/ 5
Care provider's concern for questions & worries
4.5/ 5
Care provider's friendliness and courtesy
4.6/ 5
Patient Comments
Patient comments are gathered from our Press Ganey Patient Satisfaction Survery and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
UofU Patient
June 13, 2018
I like that we have 2 expert minds looking over the data & info as well as MRI
UofU Patient
June 11, 2018
the doctor is great
UofU Patient
May 10, 2018
explained how another medication would not clash with current medication.
UofU Patient
April 24, 2018
it wasn't a good experience this time. The wait was awful. No explanation as to what was happening, we just sat and waited alone in the exam room. A couple of times someone would come in but for the most part we just waited and waited.
UofU Patient
March 13, 2018
He explained things very well and so that I could understand.
UofU Patient
March 10, 2018
good
UofU Patient
March 05, 2018
This was probably the best visit yet ! I felt like I was more involved with my care rather then just another person to get out the door
UofU Patient
January 09, 2018
I'm going to keep saying it's a good experience
UofU Patient
November 16, 2017
Very comforting due to answering any and all Q&A!
UofU Patient
October 23, 2017
if my problems were more pressing I think more concern would've been shown buy currently it's just in a holding pattern so nothing to be worried about
UofU Patient
October 20, 2017
Even when I am not with my doctor the care I get from the fellow or new physician is excellent.
UofU Patient
October 15, 2017
Dr. Paz Soldan is fantastic! Always patient and informative. Always takes time to explain things and seems to appreciate the fact that I'm knowledgeable about the condition and that I can ask and understand more technical things. Couldn't ask for a better doctor!
UofU Patient
May 16, 2017
Dr. Paz Soldan is an amazing Neurologist. He listens to my concerns and includes me in my treatment plans. He is kind, caring and very thorough. He basically saved my life as I have a very rare neurological illness and he is one of two Neurologists in Utah that is qualified to take care of me. At the first visit he was able to diagnose me and started treatment right away. I don't ever want to have to see another doctor.
UofU Patient
April 04, 2017
Dr. Paz Soldan is the best I have had. He is excellent.
UofU Patient
March 13, 2017
very satisfied with my doctor
UofU Patient
February 12, 2017
good
UofU Patient
January 24, 2017
EXCELLENT
UofU Patient
November 03, 2016
His excellent knowledge base and what I think are sound decisions overcame my bit of intimidation. I never feel super comfortable around doctors. I do a tremendous amount of research on up to date and pubmed so I am not ill informed about my diseases. It was clear his knowledge of uncommon conditions was great. I've had a lot of doctors give me bad advice or odd information. I walked into one doctor who was rapidly googling sarcoidosis when I arrived and he claimed to know all about it. Dr Paz Soldan is the real deal and I'm so thankful he knew more about Sjogrens than I did. it felt good. And the resident was so easy to talk to and smart as well.
UofU Patient
August 03, 2016
My experience at the U of U neurology clinic was a very good one. It was definitely worth my time as everyone made me feel my case was worth their time.
UofU Patient
August 02, 2016
Dr. Paz Soldan did a great job answering my questions. I am very grateful for his help and expertise.
UofU Patient
June 19, 2016
both Drs. Paz Soldan and Valenzuela were great. I have every confidence they are knowledgable, and I am in good hands.
UofU Patient
June 07, 2016
I love my Doctor
UofU Patient
May 10, 2016
Great Doctor he and the resident did a fantastic job!
UofU Patient
April 20, 2016
I was very happy with both the doctors I saw. They were kind compassionate and very personable.
UofU Patient
April 12, 2016
Very Frustrating appointment due to the time I was able to spend with this Doctor discussing my health after waiting Months to get an appointment scheduled. I felt like the Doctor had already made up his mind about a diagnosis before he had even met me. There was definitely no time left in this appointment to investigate other options of what could be going on with my health. No time left for me to discuss with the Doctor personally, my health history. In 8 years, I have experienced many other symptoms than his total focus.
UofU Patient
March 12, 2016
It took a long time to get the appointment, but I am so glad I waited. I almost went somewhere else because it was taking so long.
UofU Patient
November 16, 2015
I was diagnosed with MS ten years ago and this was by far my most enjoyable visit with a Neurologist. I learned so much and didn't feel like I was being pushed through the office in a hurry.
UofU Patient
August 06, 2015
There is not much info out there regarding my condition so it is not the doctor's fault that not much is known. What info there is, I am confident he knows what to do.
UofU Patient
June 17, 2015
Dr. Paz Soldan is by far the best Dr. I have had regarding my MS. I have never had an exam like he gave me or a discussion with my physician like I had with Dr. Paz Soldan. It left me feeling very good and informed.
UofU Patient
May 25, 2015
The Doctor was excellent in very way.
UofU Patient
May 19, 2015
nonchalant attitude of the dr to give an opinion of treatment
UofU Patient
March 10, 2015
My husband and I(the patient ) felt at ease with our whole experience there with Dr.M.M.Paz Solden and staff. Things were told to us in "lay mans" terms which was very helpful to figure out the next steps to take.
UofU Patient
February 16, 2015
Very good experience overall.
Dr. Paz Soldán is both clinical and research Assistant Professor of Neurology in the Division of Neuroimmunology. He completed his undergraduate training at Arizona State University, where he was awarded a competitive Howard Hughes Undergraduate Research Fellowship. His scientific education then continued in the master's program at ASU and the doctoral program at Mayo Graduate School. His doctoral training was supported by an individual National Research Service Award through the NIH. He then served as postdoctoral fellow at Sun Health Research Institute. His clinical training was completed at Mayo Clinic, including medical school, internship in internal medicine, residency in neurology, and fellowship in multiple sclerosis and neuroimmunology. Research during his clinical training was supported by the National MS Society and the NIH.
His research interests include inflammatory and demyelinating diseases of the central nervous system, with his primary focus being multiple sclerosis. He has engaged in research across the spectrum from basic science, to translational, to patient focused and population-based approaches. He has utilized animal models and cellular/molecular techniques to investigate intracellular signaling pathways and stimulation of myelin repair. He has utilized animal models and advanced MR imaging techniques to investigate neurodegeneration in MS. He has utilized patient data and epidemiological approaches to investigate factors that impact the course of progressive MS. Ongoing research efforts are focused on identifying demographic, clinical, genetic and laboratory factors that better stratify phenotypes of progressive multiple sclerosis, which should enable lines of investigation that further our understanding of the degenerative component of MS pathology, with the ultimate goal of developing potential therapies. Dr. Paz Soldán is also involved in pediatric MS research through the Network of Pediatric MS Centers.
His clinical interests focus on multiple sclerosis (MS), neuromyelitis optica (NMO), and other inflammatory or demyelinating diseases of the central nervous system. His interests also include autoimmune neurologic diseases (primary, paraneoplastic, or related to systemic autoimmunity) and general clinical neurology. His education interests span from didactics to clinical teaching. He is primarily involved in clinical teaching for medical students, neurology residents and neuroimmunology fellows. He presents didactic lectures for neurology residents and has been involved in course development and didactic lectures for medical students and undergraduates.
Academic Locations
Imaging and Neurosciences Center
801-585-7575
Board Certification and Academic Information
| Academic Departments | Neurology
-
Assistant Professor |
| Academic Divisions | Neuroimmunology |
| Board Certification | American Board of Psychiatry & Neurology (Neurology) |
Education History
| Fellowship | Mayo School of Graduate Medical Education Multiple Sclerosis / Neuroimmunology Fellow |
| Residency | Mayo School of Graduate Medical Education Neurology Resident |
| Internship | Mayo School of Graduate Medical Education Preliminary Internal Medicine Intern |
| Professional Medical | Mayo Medical School Medicine M.D. |
| Postdoctoral Fellowship | Sun Health Research Institute Postdoctoral Fellow |
| Doctoral Training | Mayo Graduate School Biomedical Sciences - Molecular Neuroscience Ph.D. |
| Graduate Training | Arizona State University Zoology - Biophysics M.S. |
| Undergraduate | Arizona State University Zoology B.S. |
Selected Publications - Journal Articles
Journal Article
- Galli JR, Clardy SL, Paz Soldan MM (2016). Adult-onset Opsoclonus-Myoclonus Syndrome Associated With Ganglionic Acetylcholine Receptor Autoantibody. Neurologist, 21(6), 99-100.
- Keegan BM, Kaufmann TJ, Weinshenker BG, Kantarci OH, Schmalstieg WF, Paz Soldan MM, Flanagan EP (2016). Progressive solitary sclerosis: Gradual motor impairment from a single CNS demyelinating lesion. Neurology, 87(16), 1713-1719.
- Novotna M, Paz Soldan MM, Abou Zeid N, Kale N, Tutuncu M, Crusan DJ, Atkinson EJ, Siva A, Keegan BM, Pirko I, Pittock SJ, Lucchinetti CF, Noseworthy JH, Weinshenker BG, Rodriguez M, Kantarci OH (2015). Poor early relapse recovery affects onset of progressive disease course in multiple sclerosis. Neurology, 85(8), 722-9.
- Paz Soldan MM, Raman MR, Gamez JD, Lohrey AK, Chen Y, Pirko I, Johnson AJ (2015). Correlation of Brain Atrophy, Disability, and Spinal Cord Atrophy in a Murine Model of Multiple Sclerosis. J Neuroimaging, 25(4), 595-9.
- Paz Soldan MM, Novotna M, Abou Zeid N, Kale N, Tutuncu M, Crusan DJ, Atkinson EJ, Siva A, Keegan BM, Pirko I, Pittock SJ, Lucchinetti CF, Weinshenker BG, Rodriguez M, Kantarci OH (2015). Relapses and disability accumulation in progressive multiple sclerosis. Neurology, 84(1), 81-8.
- Paz Soldan MM, Pittock SJ, Weigand SD, Yawn BP, Rodriguez M (2012). Statin therapy and multiple sclerosis disability in a population-based cohort. Mult Scler, 18(3), 358-63.
- Ciric B, Van Keulen V, Paz Soldan M, Rodriguez M, Pease LR (2004). Antibody-mediated remyelination operates through mechanism independent of immunomodulation. J Neuroimmunol, 146(1-2), 153-61.
- Ciric B, Howe CL, Paz Soldan M, Warrington AE, Bieber AJ, Van Keulen V, Rodriguez M, Pease LR (2003). Human monoclonal IgM antibody promotes CNS myelin repair independent of Fc function. Brain Pathol, 13(4), 608-16.
- Paz Soldan MM, Warrington AE, Bieber AJ, Ciric B, Van Keulen V, Pease LR, Rodriguez M (2003). Remyelination-promoting antibodies activate distinct Ca2+ influx pathways in astrocytes and oligodendrocytes: relationship to the mechanism of myelin repair. Mol Cell Neurosci, 22(1), 14-24.
- Mitsunaga Y, Ciric B, Van Keulen V, Warrington AE, Paz Soldan M, Bieber AJ, Rodriguez M, Pease LR (2002). Direct evidence that a human antibody derived from patient serum can promote myelin repair in a mouse model of chronic-progressive demyelinating disease. FASEB J, 16(10), 1325-7.
Review
- Paz Soldan MM, Pirko I (2012). Biogenesis and significance of central nervous system myelin. [Review]. Semin Neurol, 32(1), 9-14.
- Paz Soldan MM, Rodriguez M (2002). Heterogeneity of pathogenesis in multiple sclerosis: implications for promotion of remyelination. [Review]. J Infect Dis, 186 Suppl 2, S248-53.
- Warrington AE, Bieber AJ, Ciric B, Van Keulen V, Pease LR, Mitsunaga Y, Paz Soldan MM, Rodriguez M (2001). Immunoglobulin-mediated CNS repair. [Review]. J Allergy Clin Immunol, 108(4 Suppl), S121-5.
Editorial
Abstract
- Carlson NG, Schmidt LA, Wood B, Clendennon C, Weber LM, Paz Soldan MM, Rose JW (2017). Remyelination following oral administration of dimethyl fumarate in the Theiler’s murine encephalomyelitis virus model of multiple sclerosis [Abstract]. Multiple Sclerosis Journal, 23(S3), 622.
- Keegan BM, Kaufmann TJ, Weinshenker BG, Kantarci OH, Schmalstieg WF, Paz Soldan MM, Flanagan EP (2017). Motor progression from a single critically located demyelinating lesion in paucisclerotic MS [Abstract]. Multiple Sclerosis Journal, 23(S3), 437.
- Baldassari LE, Seraj H, Husebye CD, Paz Soldn MM, Martins TB, Carlson NG, Rose JW (2017). Cytokine Profiles Across DR2 Haplotype and Vitamin D Status in the Intermountain Multiple Sclerosis Project [Abstract]. 2017 Annual Meeting of the Consortium of Multiple Sclerosis Centers, ND03.
- Wong K, Marini E, Clardy SL, DeWitt LD, Klein JM, Paz Soldan MM, Rose JW (2017). Dimethyl Fumarate in Relapsing Remitting Multiple Sclerosis: Effects of Dose Reduction on Lymphopenia [Abstract]. Neurology, 88(16 supplement), P5.373.
- Baldassari LE, Seraj H, Husebye CD, Paz Soldn MM, Martins TB, Carlson NG, Rose JW (2017). Baseline characteristics and cytokine profiles across demographic subsets in the Intermountain Multiple Sclerosis Project [Abstract]. Neurology, 88(16 supplement), P1.382.
- Piquet AL, Baldassari LE, Paz Soldn MM (2017). Highly active relapsing remitting multiple sclerosis following hematopoietic stem cell transplantation: a case report [Abstract]. Neurology, 88(16 supplement), P6.355.
- Samara VC, Sweeney M, Carlson H, Paz Soldan MM, Greenlee JE, Carlson NG, Rose JW, Clardy SL (2016). Transverse Myelitis in Veterans [Abstract]. Annals of Neurology, 80(s20), S203.
- Carlson NG, Schmidt LA, Wood B, Clendennen C, Weber LM, Paz Soldan MM, Rose JW (2016). Therapeutic effects of oral dimethyl fumarate in the Thiler's murine encephalomyelitis virus model of multiple sclerosis [Abstract]. Multiple Sclerosis Journal, 22(S3), 163.
- Conway BL, Zeydan B, Novotna M, Paz Soldan MM, Tutuncu M, Siva A, Rodriguez M, Kantarci OH (2016). Amount and time to maximal recovery from multiple sclerosis relapses declines with age [Abstract]. Multiple Sclerosis Journal, 22(S3), 111.
- Carlson H, Haringer V, Sweeney M, Rose JW, Carlson NG, Greenlee JE, Paz Soldan MM, Clardy SL (2016). Transverse Myelitis in Veterans: Epidemiology and Outcomes [Abstract]. Neurology, 86(16 supplement), P6.129.
- Novotna M, Conway B, Zeydan B, Paz Soldan MM, Abou Zeid N, Kale N, Tutuncu M, Kantarci OH (2016). Predicting the End of Symptomatic Relapses and Disease Modifying Treatment Use Decisions in Progressive Multiple Sclerosis [Abstract]. Neurology, 86(16 supplement), S24.001.
- Keegan BM, Kaufmann TJ, Weinshenker BG, Kantarci OH, Schmalstieg WF, Paz Soldan MM, Flanagan EP (2016). Progressive Solitary Sclerosis: Insidious Motor Impairment Localized to an Isolated CNS Demyelinating Lesion [Abstract]. Neurology, 86(16 supplement), P3.008.
- Sweeney ML, Paz Soldan MM, Lowichik A, Sweney MT, Clardy SL (2016). A Pediatric Patient with ANNA-1 Associated Opsoclonus Myoclonus and Epilepsia Partialis Continua [Abstract]. Neurology, 86(16 supplement), P5.137.
- Galli J, Greenlee JE, Paz Soldan MM, Clardy SL (2016). Epidemiology of Stiff Person Syndrome in the United States Veterans Health Administration Database [Abstract]. Neurology, 86(16 supplement), P3.356.
- Galli JR, Clardy SL, Paz Soldn MM (2015). Ganglionic acetylcholine receptor autoantibody-associated opsoclonus-myoclonus syndrome [Abstract]. Annals of Neurology, 78(S19), S75.
- Toledano M, Weinshenker BG, Paz Soldn MM (2015). Demographics and characteristics of multiple sclerosis-related hypothermia [Abstract]. Multiple Sclerosis Journal, 21(S11), 729-730.
- Novotna M, Paz Soldn MM, Abou Zeid N, Kale N, Tutuncu M, Kantarci OH (2015). Defining the overlapping period of relapsing-remitting and progressive phases of multiple sclerosis for continuing disease modifying treatments [Abstract]. Multiple Sclerosis Journal, 21(S11), 91-92.
- Carlson NG, Schmidt L, Redd J, Bellamkonda S, Wood B, Weber LM, Paz Soldn MM, Rose JW (2015). Vulnerability of oligodendrocyte precursor cells to death is modulated by key prostaglandins [Abstract]. Multiple Sclerosis Journal, 21(S11), 467-468.
- Paz Soldn MM, Schmidt LA, Wood BL, Rose JW, Carlson NG (2015). Prostaglandin F2α Receptor Mediates Oligodendrocyte Precursor Injury/Death: Potential Role in Multiple Sclerosis [Abstract]. Neurology, 84(14 supplement), P5.210.
- Paz Soldan MM, Flanagan EP, Kantarci OH (2014). Highly active multiple sclerosis and Epstein-Barr virus reactivation [Abstract]. Multiple Sclerosis Journal, 20(S1), 229-230.
- Paz Soldan MM, Gamez JD, Raman M, Macura SI, Johnson AJ, Pirko I (2014). MRI measured brain and spinal cord atrophy differ between mouse strains in a murine model of MS [Abstract]. ISMRM 2014; Abstract No. 3382.
- Novotna M, Tutuncu M, Paz Soldan MM, Crusan DJ, Atkinson EJ, Kantarci OH (2014). Early relapse-recovery impacts progressive disease course in multiple sclerosis [Abstract]. Neurology, 82(10 supplement), S34.006.
- Paz Soldan MM, Martina N, Crusan DJ, Atkinson EJ, Kantarci OH (2013). Pre- and post-progression relapses impact disability in progressive multiple sclerosis [Abstract]. Multiple Sclerosis Journal, 19(S1), 65.
- Paz Soldan MM, Tutuncu M, Tang J, Abou Zeid N, Kale N, Crusan DJ, Atkinson EJ, Siva A, Pittock SJ, Pirko I, Keegan BM, Lucchinetti CF, Noseworthy JH, Rodriguez M, Weinshenker BG, Kantarci OH (2013). Predicting tempo of post-progression disability accumulation in multiple sclerosis [Abstract]. Neurology, 80(7 supplement), P02.147.
- Paz Soldan MM, Gamez JD, Johnson AJ, Lohrey AK, Chen Y, Pirko I (2011). Correlation of brain atrophy, disability and spinal cord atrophy in a murine model of MS [Abstract]. Annals of Neurology, 70(Supplement 15), S70 (T1715).
- Paz Soldn MM, Rodriguez M (1999). Remyelination promoting antibodies mediate Ca2+ responses in oligodendrocytes [Abstract]. Society for Neuroscience Southern Minnesota Chapter Poster Session, Rochester, MN.