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Specialties
Board Certification
American Board of Internal Medicine (Sub: Cardiovascular Disease)National Board of Echocardiography -
Board Certification and Academic Information
Academic Departments Internal Medicine -Associate Professor
Academic Divisions Cardiovascular Medicine
Board Certification American Board of Internal Medicine (Sub: Cardiovascular Disease)National Board of EchocardiographyEducation history
Research Fellow Cardiology - Boston Children’s Hospital Research Fellow Research Fellow Cardiovascular Research Center - Massachusetts General Hospital Research Fellow Fellowship Cardiovascular Diseases - Massachusetts General Hospital Clinical Fellow Residency Internal Medicine, ABIM Research Pathway - University of California, San Francisco Resident Internship Internal Medicine - University of California, San Francisco Intern Professional Medical Medicine, Neuroscience - Johns Hopkins University School of Medicine M.D., Ph.D. Undergraduate Biology, Philosophy - Cornell University B.A. Selected Publications
Journal Article
- Cluntun AA, Visker JR, Velasco-Silva JN, Lang MJ, Cedeo-Rosario L, Shankar TS, Hamouche R, Ling J, Kim JE, Toshniwal AG, Low HK, Cunningham CN, Carrington J, Catrow JL, Pearce Q, Jeong MY, Bott AJ, Narbona-Prez J, Stanley CE, Li Q, Eberhardt DR, Morgan JT, Yadav T, Wells CE, Ramadurai DKA, Swiatek WI, Chaudhuri D, Rothstein JD, Muoio DM, Paulo JA, Gygi SP, Baker SA, Navankasattusas S, Cox JE, Funai K, Drakos SG, Rutter J, Ducker GS (2024). Direct mitochondrial import of lactate supports resilient carbohydrate oxidation. bioRxiv. (Read full article)
- Visker JR, Cluntun AA, Velasco-Silva JN, Eberhardt DR, Cedeno-Rosario L, Shankar TS, Hamouche R, Ling J, Kwak H, Hillas JY, Aist I, Tseliou E, Navankasattusas S, Chaudhuri D, Ducker GS, Drakos SG, Rutter J (2024). Enhancing mitochondrial pyruvate metabolism ameliorates ischemic reperfusion injury in the heart. JCI Insight, 9(17). (Read full article)
- Atomwise AIMS Program (2024). AI is a viable alternative to high throughput screening: a 318-target study. Sci Rep, 14(1), 7526.
- Balderas E, Lee SHJ, Shankar TS, Yin X, Balynas AM, Kyriakopoulos CP, Selzman CH, Drakos SG, Chaudhuri D (2023). Mitochondria possess a large, non-selective ionic current that is enhanced during cardiac injury. bioRxiv. (Read full article)
- Szulik MW, Valdez S, Walsh M, Davis K, Bia R, Horiuchi E, OVery S, Laxman AK, Sandaklie-Nicolova L, Eberhardt DR, Durrant JR, Sheikh H, Hickenlooper S, Creed M, Brady C, Miller M, Wang L, Garcia-Llana J, Tracy C, Drakos SG, Funai K, Chaudhuri D, Boudina S, Franklin S (2023). SMYD1a protects the heart from ischemic injury by regulating OPA1-mediated cristae remodeling and supercomplex formation. Basic Res Cardiol, 118(1), 20. (Read full article)
- Johnson JM, Peterlin AD, Balderas E, Sustarsic EG, Maschek JA, Lang MJ, Jara-Ramos A, Panic V, Morgan JT, Villanueva CJ, Sanchez A, Rutter J, Lodhi IJ, Cox JE, Fisher-Wellman KH, Chaudhuri D, Gerhart-Hines Z, Funai K (2023). Mitochondrial phosphatidylethanolamine modulates UCP1 to promote brown adipose thermogenesis. Sci Adv, 9(8), eade7864. (Read full article)
- Balderas E, Eberhardt DR, Lee S, Pleinis JM, Sommakia S, Balynas AM, Yin X, Parker MC, Maguire CT, Cho S, Szulik MW, Bakhtina A, Bia RD, Friederich MW, Locke TM, Van Hove JLK, Drakos SG, Sancak Y, Tristani-Firouzi M, Franklin S, Rodan AR, Chaudhuri D (2022). Mitochondrial calcium uniporter stabilization preserves energetic homeostasis during Complex I impairment. Nat Commun, 13(1), 2769. (Read full article)
Review
- Balderas E, Lee SHJ, Rai NK, Mollinedo DM, Duron HE, Chaudhuri D (2024). Mitochondrial Calcium Regulation of Cardiac Metabolism in Health and Disease. [Review]. Physiology (Bethesda), 39(5). (Read full article)
- Lee SH, Duron HE, Chaudhuri D (2023). Beyond the TCA cycle: new insights into mitochondrial calcium regulation of oxidative phosphorylation. [Review]. Biochem Soc Trans, 51(4), 1661-1673. (Read full article)
Book Chapter
- Balderas E, Sommakia S, Eberhardt D, Lee S, Chaudhuri D (2023). The structural era of the mitochondrial calcium uniporter. In Satin LS, Ben-Johny M, Dick IE (Eds.), Calcium Signals: From single molecules to physiology (pp. 12-1 to 12-22).
Editorial
- Balderas E, Chaudhuri D (2023). Absence (of the uniporter) makes the heart grow fonder: The cardiac response to injury adapts after prolonged EMRE inhibition. J Mol Cell Cardiol, 181, 31-32. (Read full article)