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Klaus Bielefeldt, MD, PhD

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Languages Spoken: English

Dr. Bielefeldt received his Medical Degree at the Rheinisch-Westfalische Technische Hochschul Aachen, Germany and his Internal Medicine training was completed at the Krankenhaus Maria-Hilf GmbH Möchengladbach, Germany. He was also a Research Fellow in Gastroenterology at Heinrich Heine University in Dusseldorf, Germany.

Dr. Bielefeldt completed his Internal Medicine Residency at the Univeristy of Iowa followed by his Gastroenterology Fellowship there as well. Dr. Bielefeldt receieved his PhD in Physiology at the University of Wisconsin - Madison.

Dr. Bielefeldt was an Associate Professor of Medicine at the University of Iowa before moving to the University of Pittsburgh Division of Gastroenterology where, as a Professor of Medicine, he taught and practiced until joining the faculty at the University of Utah. Dr. Bielefedlt is a Professor of Medicine in the Division of Gastroenterology at the University of Utah and is Section Chief of Gastroenterology at the Salt Lake City Veteran's Medical Center.

Clinical Locations

Veterans Administration Medical Center

500 S Foothill Blvd
Salt Lake City, UT  84149

Specialties

  • Gastroenterology

Board Certification and Academic Information

Academic Departments Internal Medicine - Professor (Clinical)
Academic Divisions Gastroenterology
Board Certification American Board of Internal Medicine
American Board of Internal Medicine (Sub: Gastroenterology)
Educational Commission for Foreign Medical Graduates

Dr. Bielefeldt received his Medical Degree at the Rheinisch-Westfalische Technische Hochschul Aachen, Germany and his Internal Medicine training was completed at the Krankenhaus Maria-Hilf GmbH Möchengladbach, Germany. He was also a Research Fellow in Gastroenterology at Heinrich Heine University in Dusseldorf, Germany.

Dr. Bielefeldt completed his Internal Medicine Residency at the Univeristy of Iowa followed by his Gastroenterology Fellowship there as well. Dr. Bielefeldt receieved his PhD in Physiology at the University of Wisconsin - Madison.

Dr. Bielefeldt was an Associate Professor of Medicine at the University of Iowa before moving to the University of Pittsburgh Division of Gastroenterology where, as a Professor of Medicine, he taught and practiced until joining the faculty at the University of Utah. Dr. Bielefedlt is a Professor of Medicine in the Division of Gastroenterology at the University of Utah and is Section Chief of Gastroenterology at the Salt Lake City Veteran's Medical Center.

Academic Locations

Board Certification and Academic Information

Academic Departments Internal Medicine - Professor (Clinical)
Academic Divisions Gastroenterology
Board Certification American Board of Internal Medicine
American Board of Internal Medicine (Sub: Gastroenterology)
Educational Commission for Foreign Medical Graduates

Research Interests

  • Visceral Pain

Education History

Fellowship University of Iowa Hospitals and Clinics
Gastroenterology
Fellow, 1997
Residency University of Iowa Hospitals and Clinics
Internal Medicine
Resident, 1995
Postdoctoral Fellowship University of Wisconsin–Madison
Physiology
Postdoctoral Fellow, 1993
Doctoral Training University of Wisconsin–Madison
Physiology
Ph.D., 1992
Research Fellow University of Wisconsin–Madison
Pharmacology
Research Fellow, 1990
Research Fellow Heinrich Heine University Düsseldorf
Gastroenterology
Research Fellow, 1989
Residency Krankenhaus Maria-Hilf GmbH
Internal Medicine
Resident, 1988
Professional Medical Rheinisch-Westfälische Technische Hochschule Aachen
Medicine
M.D., 1984

Selected Publications - Journal Articles

Journal Article

  1. Nusrat S, Syed T, Nusrat S, Chen S, Chen WJ, Bielefeldt K (2018). Assessment of Pharmaceutical Company and Device Manufacturer Payments to Gastroenterologists and Their Participation in Clinical Practice Guideline Panels. JAMA Netw Open, 1(8), e186343.
  2. Huntzinger M, Bielefeldt K (2018). Expanding the Scope of Telemedicine in Gastroenterology. Fed Pract, 35(8), 26-31.
  3. Gawron AJ, Bielefeldt K (2018). Risk of Pancreatitis Following Treatment of Irritable Bowel Syndrome With Eluxadoline. Clin Gastroenterol Hepatol, 16(3), 378-384.e2.
  4. Bielefeldt K (2017). From Harmful Treatment to Secondary Gain: Adverse Event Reporting in Dyspepsia and Gastroparesis. Dig Dis Sci, 62(11), 2999-3013.
  5. Rogal SS, Udawatta V, Akpan I, Moghe A, Chidi A, Shetty A, Szigethy E, Bielefeldt K, DiMartini A (2017). Risk factors for hospitalizations among patients with cirrhosis: A prospective cohort study. PLoS ONE, 12(11), e0187176.
  6. Rogal S, Mankaney G, Udawatta V, Good CB, Chinman M, Zickmund S, Bielefeldt K, Jonassaint N, Jazwinski A, Shaikh O, Hughes C, Humar A, DiMartini A, Fine MJ (2016). Association between opioid use and readmission following liver transplantation. Clin Transplant, 30(10), 1222-1229.
  7. Bielefeldt K (2016). Ischemic Colitis as a Complication of Medication Use: An Analysis of the Federal Adverse Event Reporting System. Dig Dis Sci, 61(9), 2655-65.
  8. Thorkelson G, Bielefeldt K, Szigethy E (2016). Empirically Supported Use of Psychiatric Medications in Adolescents and Adults with IBD. Inflamm Bowel Dis, 22(6), 1509-22.
  9. Bielefeldt K (2016). Adverse events of sacral neuromodulation for fecal incontinence reported to the federal drug administration. World J Gastrointest Pharmacol Ther, 7(2), 294-305.
  10. Bielefeldt K, Levinthal DJ, Nusrat S (2016). Effective Constipation Treatment Changes More Than Bowel Frequency: A Systematic Review and Meta-Analysis. J Neurogastroenterol Motil, 22(1), 31-45.
  11. Rogal SS, Mankaney G, Udawatta V, Chinman M, Good CB, Zickmund S, Bielefeldt K, Chidi A, Jonassaint N, Jazwinski A, Shaikh O, Hughes C, Fontes P, Humar A, DiMartini A (2016). Pre-Transplant Depression Is Associated with Length of Hospitalization, Discharge Disposition, and Survival after Liver Transplantation. PLoS ONE, 11(11), e0165517.
  12. Dudekula A, Huftless S, Bielefeldt K (2015). Colectomy for constipation: time trends and impact based on the US Nationwide Inpatient Sample, 1998-2011. Aliment Pharmacol Ther, 42(11-12), 1281-93.
  13. Rogal SS, Bielefeldt K, Wasan AD, Lotrich FE, Zickmund S, Szigethy E, DiMartini AF (2015). Inflammation, psychiatric symptoms, and opioid use are associated with pain and disability in patients with cirrhosis. Clin Gastroenterol Hepatol, 13(5), 1009-16.
  14. Rogal SS, Bielefeldt K, Wasan AD, Szigethy E, Lotrich F, DiMartini AF (2015). Fibromyalgia symptoms and cirrhosis. Dig Dis Sci, 60(5), 1482-9.
  15. Nusrat S, Mahmood S, Bitar H, Tierney WM, Bielefeldt K, Madhoun MF (2015). The impact of chronic opioid use on colonoscopy outcomes. Dig Dis Sci, 60(4), 1016-23.
  16. Nusrat S, Mahmood S, Kastens D, Bielefeldt K (2014). Cholecystectomy for biliary dyskinesia in gastroparesis: mimic or misfortune? South Med J, 107(12), 757-61.
  17. Deberry JJ, Bielefeldt K, Davis BM, Szigethy EM, Hartman DJ, Coates MD (2014). Abdominal pain and the neurotrophic system in ulcerative colitis. Inflamm Bowel Dis, 20(12), 2330-9.
  18. Dudekula A, Rahim S, Bielefeldt K (2014). Time trends in gastroparesis treatment. Dig Dis Sci, 59(11), 2656-65.
  19. Bielefeldt K (2014). Black bile of melancholy or gallstones of biliary colics: historical perspectives on cholelithiasis. Dig Dis Sci, 59(11), 2623-34.
  20. Nusrat S, Bielefeldt K (2014). Fundoplication for gastroesophageal reflux disease: regional variability and factors predicting operative approach. Dis Esophagus, 27(8), 719-25.
  21. Bielefeldt K (2014). From ischochymia to gastroparesis: proposed mechanisms and preferred management of dyspepsia over the centuries. Dig Dis Sci, 59(6), 1088-98.
  22. Srinath AI, Youk AO, Bielefeldt K (2014). Biliary dyskinesia and symptomatic gallstone disease in children: two sides of the same coin? Dig Dis Sci, 59(6), 1307-15.
  23. Stopczynski RE, Normolle DP, Hartman DJ, Ying H, DeBerry JJ, Bielefeldt K, Rhim AD, DePinho RA, Albers KM, Davis BM (2014). Neuroplastic changes occur early in the development of pancreatic ductal adenocarcinoma. Cancer Res, 74(6), 1718-27.
  24. Saligram S, Bielefeldt K (2014). The two sides of opioids in cyclical vomiting syndrome. N Am J Med Sci, 6(3), 114-8.
  25. Rogal SS, Winger D, Bielefeldt K, Rollman BL, Szigethy E (2013). Healthcare utilization in chronic liver disease: the importance of pain and prescription opioid use. Liver Int, 33(10), 1497-503.
  26. Aggarwal N, Bielefeldt K (2013). Diagnostic stringency and healthcare needs in patients with biliary dyskinesia. Dig Dis Sci, 58(10), 2799-808.
  27. Bielefeldt K (2013). Regional differences in healthcare delivery for gastroparesis. Dig Dis Sci, 58(10), 2789-98.
  28. Rogal SS, Winger D, Bielefeldt K, Szigethy E (2013). Pain and opioid use in chronic liver disease. Dig Dis Sci, 58(10), 2976-85.
  29. Coates MD, Lahoti M, Binion DG, Szigethy EM, Regueiro MD, Bielefeldt K (2013). Abdominal pain in ulcerative colitis. Inflamm Bowel Dis, 19(10), 2207-14.
  30. Bielefeldt K (2013). Regional differences in hospitalizations and cholecystectomies for biliary dyskinesia. J Neurogastroenterol Motil, 19(3), 381-9.
  31. Dang K, Bielefeldt K, Gebhart GF (2013). Cyclophosphamide-induced cystitis reduces ASIC channel but enhances TRPV1 receptor function in rat bladder sensory neurons. J Neurophysiol, 110(2), 408-17.
  32. Bielefeldt K (2013). Factors influencing admission and outcomes in gastroparesis. Neurogastroenterol Motil, 25(5), 389-98, e294.
  33. Bielefeldt K (2013). Commentary: the rising tide of cholecystectomy for biliary dyskinesia - author's reply. Aliment Pharmacol Ther, 37(4), 495.
  34. Levinthal DJ, Rahman A, Nusrat S, OLeary M, Heyman R, Bielefeldt K (2013). Adding to the burden: gastrointestinal symptoms and syndromes in multiple sclerosis. Mult Scler Int, 2013, 319201.
  35. Nusrat S, Levinthal D, Bielefeldt K (2013). Hospitalization rates and discharge status in multiple sclerosis. Mult Scler Int, 2013, 436929.
  36. Bielefeldt K (2013). The rising tide of cholecystectomy for biliary dyskinesia. Aliment Pharmacol Ther, 37(1), 98-106.
  37. Nusrat S, Bielefeldt K (2013). Gastroparesis on the rise: incidence vs awareness? Neurogastroenterol Motil, 25(1), 16-22.
  38. Nusrat S, Yadav D, Bielefeldt K (2012). Pain and opioid use in chronic pancreatitis. Pancreas, 41(2), 264-70.
  39. Nusrat S, Gulick E, Levinthal D, Bielefeldt K (2012). Anorectal dysfunction in multiple sclerosis: a systematic review. ISRN Neurol, 2012, 376023.
  40. Nusrat S, Roy PM, Bielefeldt K (2012). Wireless ambulatory pH studies: manometric or endoscopic guidance? Dis Esophagus, 25(1), 26-32.
  41. Dudekula A, OConnell M, Bielefeldt K (2011). Hospitalizations and testing in gastroparesis. J Gastroenterol Hepatol, 26(8), 1275-82.
  42. Shinoda M, La JH, Bielefeldt K, Gebhart GF (2010). Altered purinergic signaling in colorectal dorsal root ganglion neurons contributes to colorectal hypersensitivity. J Neurophysiol, 104(6), 3113-23.
  43. Christianson JA, Bielefeldt K, Malin SA, Davis BM (2010). Neonatal colon insult alters growth factor expression and TRPA1 responses in adult mice. Pain, 151(2), 540-9.
  44. Bielefeldt K (2010). Approaching patients with irritable bowel syndrome.LID - 10.3410/M2-50 [doi]LID - 50 [pii]. F1000 Med Rep, 2.
  45. Bielefeldt K, Raza N, Zickmund SL (2009). Different faces of gastroparesis. World J Gastroenterol, 15(48), 6052-60.
  46. Bielefeldt K, Levinthal D (2009). Pieces of a puzzle: Permeability, proinflammatory pathways and pain? Pain, 146(1-2), 7-8.
  47. Raza N, Bielefeldt K (2009). Discriminative value of anorectal manometry in clinical practice. Dig Dis Sci, 54(11), 2503-11.
  48. Levinthal DJ, Bielefeldt K (2009). Differences in post-inflammatory hypersensitivity between splanchnic and pelvic afferents: mechanisms and implications for human disease. Gut, 58(10), 1317-8.
  49. McIlwrath SL, Davis BM, Bielefeldt K (2009). Deletion of P2X3 receptors blunts gastro-oesophageal sensation in mice. Neurogastroenterol Motil, 21(8), 890-e66.
  50. Remes-Troche JM, Bielefeldt K, Rao SS (2009). [It's necessary the anorrectal manometry for evaluation of patients with chronic constipation?]. Rev Gastroenterol Mex, 74(2), 175-8.
  51. Malin SA, Christianson JA, Bielefeldt K, Davis BM (2009). TPRV1 expression defines functionally distinct pelvic colon afferents. J Neurosci, 29(3), 743-52.
  52. Bielefeldt K, Davis BM (2008). Differential effects of ASIC3 and TRPV1 deletion on gastroesophageal sensation in mice. Am J Physiol Gastrointest Liver Physiol, 294(1), G130-8.
  53. Dang K, Lamb K, Cohen M, Bielefeldt K, Gebhart GF (2008). Cyclophosphamide-induced bladder inflammation sensitizes and enhances P2X receptor function in rat bladder sensory neurons. J Neurophysiol, 99(1), 49-59.
  54. Zhong F, Christianson JA, Davis BM, Bielefeldt K (2008). Dichotomizing axons in spinal and vagal afferents of the mouse stomach. Dig Dis Sci, 53(1), 194-203.
  55. Sugiura T, Bielefeldt K, Gebhart GF (2007). Mouse colon sensory neurons detect extracellular acidosis via TRPV1. Am J Physiol Cell Physiol, 292(5), C1768-74.
  56. Lamb K, Gebhart GF, Bielefeldt K (2007). Luminal stimuli acutely sensitize visceromotor responses to distension of the rat stomach. Dig Dis Sci, 52(2), 488-94.
  57. Bielefeldt K, Zhong F, Koerber HR, Davis BM (2006). Phenotypic characterization of gastric sensory neurons in mice. Am J Physiol Gastrointest Liver Physiol, 291(5), G987-97.
  58. Bielefeldt K, Lamb K, Gebhart GF (2006). Convergence of sensory pathways in the development of somatic and visceral hypersensitivity. Am J Physiol Gastrointest Liver Physiol, 291(4), G658-65.
  59. Ma X, Bielefeldt K, Tan ZY, Whiteis CA, Snitsarev V, Abboud FM, Chapleau MW (2006). Dual mechanisms of angiotensin-induced activation of mouse sympathetic neurones. J Physiol, 573(Pt 1), 45-63.
  60. Bhat YM, Bielefeldt K (2006). Capsaicin receptor (TRPV1) and non-erosive reflux disease. Eur J Gastroenterol Hepatol, 18(3), 263-70.
  61. Lamb K, Zhong F, Gebhart GF, Bielefeldt K (2006). Experimental colitis in mice and sensitization of converging visceral and somatic afferent pathways. Am J Physiol Gastrointest Liver Physiol, 290(3), G451-7.
  62. Bhat YM, McGrath KM, Bielefeldt K (2006). Wireless esophageal pH monitoring: new technique means new questions. J Clin Gastroenterol, 40(2), 116-21.
  63. Dang K, Bielefeldt K, Gebhart GF (2005). Differential responses of bladder lumbosacral and thoracolumbar dorsal root ganglion neurons to purinergic agonists, protons, and capsaicin. J Neurosci, 25(15), 3973-84.
  64. Sugiura T, Dang K, Lamb K, Bielefeldt K, Gebhart GF (2005). Acid-sensing properties in rat gastric sensory neurons from normal and ulcerated stomach. J Neurosci, 25(10), 2617-27.
  65. Kang YM, Lamb K, Gebhart GF, Bielefeldt K (2005). Experimentally induced ulcers and gastric sensory-motor function in rats. Am J Physiol Gastrointest Liver Physiol, 288(2), G284-91.
  66. Sugiuar T, Bielefeldt K, Gebhart GF (2004). TRPV1 function in mouse colon sensory neurons is enhanced by metabotropic 5-hydroxytryptamine receptor activation. J Neurosci, 24(43), 9521-30.
  67. Kang YM, Bielefeldt K, Gebhart GF (2004). Sensitization of mechanosensitive gastric vagal afferent fibers in the rat by thermal and chemical stimuli and gastric ulcers. J Neurophysiol, 91(5), 1981-9.
  68. Lamb K, Gebhart GF, Bielefeldt K (2004). Increased nerve growth factor expression triggers bladder overactivity. J Pain, 5(3), 150-6.
  69. Dang K, Bielefeldt K, Gebhart GF (2004). Gastric ulcers reduce A-type potassium currents in rat gastric sensory ganglion neurons. Am J Physiol Gastrointest Liver Physiol, 286(4), G573-9.
  70. Lamb K, Kang YM, Gebhart GF, Bielefeldt K (2003). Gastric inflammation triggers hypersensitivity to acid in awake rats. Gastroenterology, 125(5), 1410-8.
  71. Joshi SK, Lamb K, Bielefeldt K, Gebhart GF (2003). Arylacetamide kappa-opioid receptor agonists produce a tonic- and use-dependent block of tetrodotoxin-sensitive and -resistant sodium currents in colon sensory neurons. J Pharmacol Exp Ther, 307(1), 367-72.
  72. Lamb K, Kang YM, Gebhart GF, Bielefeldt K (2003). Nerve growth factor and gastric hyperalgesia in the rat. Neurogastroenterol Motil, 15(4), 355-61.
  73. Bielefeldt K, Ozaki N, Gebhart GF (2003). Role of nerve growth factor in modulation of gastric afferent neurons in the rat. Am J Physiol Gastrointest Liver Physiol, 284(3), G499-507.
  74. Lamb K, Bielefeldt K (2003). Rapid effects of neurotrophic factors on calcium homeostasis in rat visceral afferent neurons. Neurosci Lett, 336(1), 9-12.
  75. Ozaki N, Bielefeldt K, Sengupta JN, Gebhart GF (2002). Models of gastric hyperalgesia in the rat. Am J Physiol Gastrointest Liver Physiol, 283(3), G666-76.
  76. Gebhart GF, Bielefeldt K, Ozaki N (2002). Gastric hyperalgesia and changes in voltage gated sodium channel function in the rat. Gut, 51 Suppl 1, i15-8.
  77. Bielefeldt K, Ozaki N, Whiteis C, Gebhart GF (2002). Amitriptyline inhibits voltage-sensitive sodium currents in rat gastric sensory neurons. Dig Dis Sci, 47(5), 959-66.
  78. Bielefeldt K, Ozaki N, Gebhart GF (2002). Mild gastritis alters voltage-sensitive sodium currents in gastric sensory neurons in rats. Gastroenterology, 122(3), 752-61.
  79. Bielefeldt K, Ozaki N, Gebhart GF (2002). Experimental ulcers alter voltage-sensitive sodium currents in rat gastric sensory neurons. Gastroenterology, 122(2), 394-405.
  80. Ma X, Chapleau MW, Whiteis CA, Abboud FM, Bielefeldt K (2001). Angiotensin selectively activates a subpopulation of postganglionic sympathetic neurons in mice. Circ Res, 88(8), 787-93.
  81. Fazan R Jr, Whiteis CA, Chapleau MW, Abboud FM, Bielefeldt K (2001). Slow inactivation of sodium currents in the rat nodose neurons. Auton Neurosci, 87(2-3), 209-16.
  82. Bielefeldt K (2000). Differential effects of capsaicin on rat visceral sensory neurons. Neuroscience, 101(3), 727-36.
  83. Evans JR, Bielefeldt K (2000). Regulation of sodium currents through oxidation and reduction of thiol residues. Neuroscience, 101(1), 229-36.
  84. Bielefeldt K, Whiteis CA, Chapleau MW, Abboud FM (1999). Nitric oxide enhances slow inactivation of voltage-dependent sodium currents in rat nodose neurons. Neurosci Lett, 271(3), 159-62.
  85. Bielefeldt K (1999). Molecular diversity of voltage-sensitive calcium channels in smooth muscle cells. J Lab Clin Med, 133(5), 469-77.
  86. Yorek M, Jaipaul N, Dunlap J, Bielefeldt K (1999). Endothelin-stimulated Ca2+ mobilization by 3T3-L1 adipocytes is suppressed by tumor necrosis factor-alpha. Arch Biochem Biophys, 361(2), 241-51.
  87. Li Z, Chapleau MW, Bates JN, Bielefeldt K, Lee HC, Abboud FM (1998). Nitric oxide as an autocrine regulator of sodium currents in baroreceptor neurons. Neuron, 20(5), 1039-49.
  88. Oh ST, Yedidag E, Bielefeldt K (1998). Differential effects of progesterone and its analogues on the contractility of the murine jejunum in vitro. J Surg Res, 75(1), 1-5.
  89. Bielefeldt K, Sharma RV, Whiteis C, Yedidag E, Abboud FM (1997). Tacrolimus (FK506) modulates calcium release and contractility of intestinal smooth muscle. Cell Calcium, 22(6), 507-14.
  90. Oh ST, Yedidag E, Conklin JL, Martin M, Bielefeldt K (1997). Calcium release from intracellular stores and excitation-contraction coupling in intestinal smooth muscle. J Surg Res, 71(1), 79-86.
  91. Bielefeldt K, Whiteis CA, Sharma RV, Abboud FM, Conklin JL (1997). Reactive oxygen species and calcium homeostasis in cultured human intestinal smooth muscle cells. Am J Physiol, 272(6 Pt 1), G1439-50.
  92. Li Z, Lee HC, Bielefeldt K, Chapleau MW, Abboud FM (1997). The prostacyclin analogue carbacyclin inhibits Ca(2+)-activated K+ current in aortic baroreceptor neurones of rats. J Physiol, 501 ( Pt 2), 275-87.
  93. Bielefeldt K, Conklin JL (1997). Intestinal motility during hypoxia and reoxygenation in vitro. Dig Dis Sci, 42(5), 878-84.
  94. Bielefeldt K, Waite L, Abboud FM, Conklin JL (1996). Nongenomic effects of progesterone on human intestinal smooth muscle cells. Am J Physiol, 271(2 Pt 1), G370-6.
  95. Bielefeldt K, Jackson MB (1994). Intramolecular and intermolecular enzymatic modulation of ion channels in excised membrane patches. Biophys J, 66(6), 1904-14.
  96. Bielefeldt K, Jackson MB (1994). Phosphorylation and dephosphorylation modulate a Ca(2+)-activated K+ channel in rat peptidergic nerve terminals. J Physiol, 475(2), 241-54.
  97. Bielefeldt K, Jackson MB (1993). A calcium-activated potassium channel causes frequency-dependent action-potential failures in a mammalian nerve terminal. J Neurophysiol, 70(1), 284-98.
  98. Bielefeldt K, Rotter JL, Jackson MB (1992). Three potassium channels in rat posterior pituitary nerve terminals. J Physiol, 458, 41-67.
  99. Bielefeldt K, Enck P, Zamboglou N, Moedder U, Erckenbrecht JF (1991). Anorectal manometry and defecography in the diagnosis of fecal incontinence. J Clin Gastroenterol, 13(6), 661-5.
  100. Enck P, Bielefeldt K, Rathmann W, Purrmann J, Tschope D, Erckenbrecht JF (1991). Epidemiology of faecal incontinence in selected patient groups. Int J Colorectal Dis, 6(3), 143-6.
  101. Herdmann J, Bielefeldt K, Enck P (1991). Quantification of motor pathways to the pelvic floor in humans. Am J Physiol, 260(5 Pt 1), G720-3.
  102. Bielefeldt K, Bass P (1991). Sodium channel blockers alter slow-wave frequency of the rat stomach in vivo. Digestion, 48(1), 43-50.
  103. Bielefeldt K, Enck P, Erckenbrecht JF (1990). Sensory and motor function in the maintenance of anal continence. Dis Colon Rectum, 33(8), 674-8.
  104. Bielefeldt K, Enck P, Zamboglou N, Erckenbrecht JF, Modder U (1990). [Radiologic diagnosis of anal incontinence]. Rontgenblatter, 43(6), 256-60.
  105. Bielefeldt K, Enck P, Erckenbrecht JF (1990). Motility changes in primary achalasia following pneumatic dilatation. Dysphagia, 5(3), 152-8.
  106. Enck P, Arping HG, Engel S, Bielefeldt K, Erckenbrecht JF (1989). Effects of cisapride on ano-rectal sphincter function. Aliment Pharmacol Ther, 3(6), 539-45.

Review

  1. Nusrat S, Syed T, Saleem R, Clifton S, Bielefeldt K (2019). Pharmacological Treatment of Opioid-Induced Constipation Is Effective but Choice of Endpoints Affects the Therapeutic Gain. [Review]. Dig Dis Sci, 64(1), 39-49.
  2. Kurin M, Bielefeldt K, Levinthal DJ (2018). Prevalence of Nausea and Vomiting in Adults Using Ropinirole: A Systematic Review and Meta-Analysis. [Review]. Dig Dis Sci, 63(3), 687-693.
  3. McKenzie P, Bielefeldt K (2018). Glass half empty? Lessons learned about gastroparesis.LID - F1000 Faculty Rev-560 [pii]LID - 10.12688/f1000research.14043.1 [doi]. [Review]. F1000Res, 7.
  4. Levinthal DJ, Bielefeldt K (2017). Systematic review and meta-analysis: Gastric electrical stimulation for gastroparesis. [Review]. Auton Neurosci, 202, 45-55.
  5. Bielefeldt K (2017). Adverse events of gastric electrical stimulators recorded in the Manufacturer and User Device Experience (MAUDE) Registry. [Review]. Auton Neurosci, 202, 40-44.
  6. Gebhart GF, Bielefeldt K (2016). Physiology of Visceral Pain. [Review]. Comprehensive Physiology, 6(4), 1609-1633.
  7. Bielefeldt K, Tuteja A, Nusrat S (2016). Disorders of gastrointestinal hypomotility.LID - 10.12688/f1000research.8658.1 [doi]LID - F1000 Faculty Rev-1897 [pii]. [Review]. F1000Res, 5.
  8. Khan MA, Nusrat S, Khan MI, Nawras A, Bielefeldt K (2015). Low-FODMAP Diet for Irritable Bowel Syndrome: Is It Ready for Prime Time? [Review]. Dig Dis Sci, 60(5), 1169-77.
  9. Bielefeldt K, Saligram S, Zickmund SL, Dudekula A, Olyaee M, Yadav D (2014). Cholecystectomy for biliary dyskinesia: how did we get there? [Review]. Dig Dis Sci, 59(12), 2850-63.
  10. Levinthal DJ, Bielefeldt K (2014). Adult cyclical vomiting syndrome: a disorder of allostatic regulation? [Review]. Exp Brain Res, 232(8), 2541-7.
  11. Srinath A, Saps M, Bielefeldt K (2014). Biliary dyskinesia in pediatrics. [Review]. Pediatr Ann, 43(4), e83-8.
  12. Nusrat S, Nusrat S, Bielefeldt K (2012). Reflux and sex: what drives testing, what drives treatment? [Review]. Eur J Gastroenterol Hepatol, 24(3), 233-47.
  13. Bielefeldt K (2012). Gastroparesis: concepts, controversies, and challenges. [Review]. Scientifica (Cairo), 2012, 424802.
  14. Bielefeldt K, Davis B, Binion DG (2009). Pain and inflammatory bowel disease. [Review]. Inflamm Bowel Dis, 15(5), 778-88.
  15. Christianson JA, Bielefeldt K, Altier C, Cenac N, Davis BM, Gebhart GF, High KW, Kollarik M, Randich A, Undem B, Vergnolle N (2009). Development, plasticity and modulation of visceral afferents. [Review]. Brain Res Rev, 60(1), 171-86.
  16. Domsic R, Fasanella K, Bielefeldt K (2008). Gastrointestinal manifestations of systemic sclerosis. [Review]. Dig Dis Sci, 53(5), 1163-74.
  17. Zickmund SL, Brown KE, Bielefeldt K (2007). A systematic review of provider knowledge of hepatitis C: is it enough for a complex disease? [Review]. Dig Dis Sci, 52(10), 2550-6.
  18. Bielefeldt K, Christianson JA, Davis BM (2005). Basic and clinical aspects of visceral sensation: transmission in the CNS. [Review]. Neurogastroenterol Motil, 17(4), 488-99.
  19. Hisel TM, Bielefeldt K, Joss JD (1999). Asthma and gastroesophageal reflux. [Review]. J Am Osteopath Assoc, 99(10 Su Pt 1), S9-13.
  20. Bielefeldt K, Berges W (1990). [Disorders of esophageal function as a cause of thoracic pain]. [Review]. Leber Magen Darm, 2(2), 61-4, 67-70.
  21. Bielefeldt K, Enck P, Wienbeck M (1990). Diagnosis and treatment of fecal incontinence. [Review]. Dig Dis, 8(3), 179-88.
  22. Bielefeldt K, Berges W (1989). [Therapy of functional dysphagia]. [Review]. Dtsch Med Wochenschr, 114(39), 1492-5.
  23. Bielefeldt K, Berges W (1989). [Diagnosis of functional dysphagia]. [Review]. Dtsch Med Wochenschr, 114(38), 1450-5.
  24. Bielefeldt K, Purrmann J, Strohmeyer G (1989). [Nutrition and Crohn disease--an etiologic factor?]. [Review]. Z Gastroenterol, 27(9), 455-8.

Book Chapter

  1. Bielefeldt K, Gebhart GF (2013). Visceral pain: basic mechanisms. In McMahon SB, Klotzenburg M, Tracey I, Turk DC (Eds.), Textbook of Pain (6th Edition, pp. 703-17). Elsevier Churchill Livingstone.
  2. Bielefeldt K, Gebhart GF (2010). Visceral Pain. In Lynch ME, Craig KD, Peng PWH (Eds.), Clinical Pain Management: A practical guide. Wiley-Blackwell.
  3. Bielefeldt K (2010). Visceral hypersensitivity. In Parkman HP, Rao SSC, McCallum RW (Eds.), GI Motility Testing: A Laboratory and Office Handbook (pp. 453-63). SLACK Incorporated.
  4. Bielefeldt K, Bauer AJ (2009). Approach to the Patient with Ileus and Obstruction. doi: 10.1002/9781444300758.ch17. In Yamada T (Ed.), Principles of Clinical Gastroenterology. Oxford, UK: Wiley-Blackwell.
  5. Bielefeldt K (2009). Approach to the Patient with Ileus and Obstruction. doi: 10.1002/9781444303414.ch4. In Yamada T (Ed.), Atlas of Gastroenterology (4th Edition). Oxford, UK: Wiley-Blackwell.
  6. Bielefeldt K, Gebhart GF (2008). Outcomes, efficacy and complications form management of visceral pain. In Benzon HT, Rathmell JP, Wu CL, Turk DC, Argoff CE (Eds.), Raj’s Practical Management of Pain (4th Edition, pp. 529-40). Philadelphia: Mosby Elsevier.
  7. Bielefeldt K (2007). Neurochemical and molecular basis of peripheral sensitization. In Pasricha J, Gebhart GF (Eds.), Chronic abdominal and visceral pain: theory and practice (pp. 67-83). New York, London: Informa.
  8. Bielefeldt K, Gebhart GF (2007). Visceral afferents. In Kaas J (Ed.), Evolution of Nervous System in Mammals (pp. 237-52). Elsevier.
  9. Bielefeldt K, Gebhart GF (2006). Visceral pain: basic mechanisms. In McMahon SB, Klotzenburg M (Eds.), Textbook of Pain (pp. 721-36). Elsevier Churchill Livingstone.
  10. Gebhart GF, Kuner R, Jones RC, Bielefeldt K (2004). Visceral hypersensitivity. In Brune K, Handwerker HO (Eds.), Hyperalgesia: Molecular Mechanisms and Clinical Implications (Progress in Pain Research and Management) (30, pp. 87-104). Seattle: IASP Press.
  11. Strohmeyer G, Bielefeldt K (1992). [Irritable bowel syndrome]. In Hornbostel H, Kaufmann W, Siegenthaler W (Eds.), [Internal Medicine in Practice and Clinic]. Germany: Georg Thieme Verlag.
  12. Bielefeldt K, Strohmeyer G (1991). Incomplete relaxation of the L.E.S. may be observed in healthy people. In Giuli R, McCallum R, Skinner D (Eds.), Primary motility disorders of the esophagus. Amsterdam, New York: Elsevier.
  13. Bielefeldt K, Strohmeyer G (1991). What is the basis of peristaltic nature of swallowing induced peristalsis? In Giuli R, McCallum R, Skinner D (Eds.), Primary motility disorders of the esophagus. Amsterdam, New York: Elsevier.

Case Report

  1. Levinthal DJ, Bielefeldt K (2012). Pain without nociception? Eur J Gastroenterol Hepatol, 24(3), 336-9.
  2. Eid KR, Costa G, Bond GJ, Cruz RJ, Rubin E, Bielefeldt K, Koritsky D, Abu-Elmagd KM (2010). An innovative sphincter preserving pull-through technique with en bloc colon and small bowel transplantation. Am J Transplant, 10(8), 1940-6.
  3. Meyer MJ, Goldschneider KR, Bielefeldt K, Zeltzer L, Lackner J, Keefer L (2008). Functional abdominal pain in adolescence: a biopsychosocial phenomenon. J Pain, 9(11), 984-90.
  4. Bielefeldt K, Zamboglou N, Bender H (1990). [The spastic pelvic floor syndrome]. Rofo Fortschr Geb Rontgenstr Neuen Bildgeb Verfahr, 152(1), 105-6.

Letter

  1. Bielefeldt K (2016). Adverse Events After Implantation of a Magnetic Sphincter Augmentation Device for Gastroesophageal Reflux. [Letter to the editor]. Clin Gastroenterol Hepatol, 14(10), 1507-8.
  2. Bielefeldt K (2014). Bariatric surgery versus intensive medical therapy for diabetes. [Letter to the editor]. N Engl J Med, 371(7), 681-2.
  3. Bielefeldt K (2005). Playing with open cards. [Letter to the editor]. Am J Gastroenterol, 100(12), 2814-5; author reply 2815.
  4. Bielefeldt K (1995). Preventing adverse effects. [Letter to the editor]. Ann Intern Med, 122(12), 962-3; author reply 964.
  5. Bielefeldt K (1995). The body of the text: Textual training and the literature elite [Letter to the editor]. Q J Speech, 81, 100-2.
  6. Bielefeldt K, Erckenbrecht JF (1989). [Etiology of "microscopic colitis"]. [Letter to the editor]. Dtsch Med Wochenschr, 114(49), 1940-1.
  7. Bielefeldt K (1988). [Drug therapy of Campylobacter pylori-associated gastritis]. [Letter to the editor]. Dtsch Med Wochenschr, 113(38), 1495-6.

Abstract

  1. Bielefeldt K, Ozaki N, Gebhart GF (2002). Effects of persistent gastric injury on rat spinal afferent neurons [Abstract]. Gastroenterol, 122, A653.
  2. Ozaki N, Bielefeldt K, Gebhart GF (2001). Characterization of visceromotor response to gastric distension in normal and gastric ulcer induced rats [Abstract]. J Pain, 2, S26.
  3. Bielefeldt K, Ozaki N, Gebhart GF (2001). Experimental ulcers alter voltage-dependent sodium currents in rat gastric sensory neurons [Abstract]. Gastroenterol, 120, A57.
  4. Su X, Kardos SL, Bielefeldt K, Wachtel R, Gebhart GF (2001). U50,488 modulation of sodium currents in colon sensory neurons [Abstract]. Gastroenterol, 120, A200.
  5. Bielefeldt K, Ozaki N, Gebhart GF (2001). Nerve growth factor and sensitization of gastric afferent neurons [Abstract]. Digestion, 63, 267.
  6. Ozaki N, Bielefeldt K, Gebhart GF (2001). Iodoacetamide ingestion induces gastric hyperalgesia in the rat [Abstract]. Digestion, 63, 274.
  7. Bielefeldt K, Ozaki N, Gebhart GF (2001). Differential effects of gastritis on nodose and dorsal root afferents in the rat [Abstract]. Neurogastroenterology and Motility, 13, 375.
  8. Bielefeldt K (2000). Differential effect of capsaicin on rat visceral sensory neurons [Abstract]. Gastroenterol, 118, A379.
  9. Evans JR, Sigmundsson HK, Bielefeldt K (2000). Prostaglandin E2 alters the calcium homeostasis in rat visceral sensory neurons [Abstract]. Gastroenterol, 118, A380.
  10. Fazan R, Abboud FM, Chapleau MW, Bielefeldt K (1999). Effects of nitric oxide on inactivation processes of sodium currents in nodose neurons [Abstract]. FASEB Abstract, A777.
  11. Evans J, Bielefeldt K (1999). Fast and slow inactivation of sodium currents is differentially regulated in NB41a3 cells [Abstract]. J Invest Med, 47, 243A.
  12. Bielefeldt K (1998). Differential distribution of calcium channel subunits in antral and pyloric smooth muscle [Abstract]. Gastroenterol, 114, A721.
  13. Fazan R, Chapleau MW, Abboud FM, Bielefeldt K (1998). Use-dependent modulation of sodium channels in nodose neurons [Abstract]. Neurosci Abstracts, 24, 1076.
  14. Bielefeldt K, Conklin JL (1996). Reactive oxygen species and calcium homeostasis in human intestinal smooth muscle cells [Abstract]. Gastroenterol, 110, A634.
  15. Bielefeldt K, Conklin JL (1996). Reactive oxygen species and calcium and intestinal motility in an in vitro model of reperfusion injury [Abstract]. Gastroenterol, 110, A634.
  16. Bielefeldt K, Conklin JL (1996). Tumor necrosis factor alters calcium homeostasis and redox state in intestinal smooth muscle cells [Abstract]. Dig Dis Sci, 41, 1896.
  17. Bielefeldt K, Waite L, Conklin JL, Abboud F (1995). Non-genomic effects of progesterone on human intestinal smooth muscle cells [Abstract]. Gastroenterol, 108, A571.
  18. Bielefeldt K, Jackson MB (1992). Calcium- & phosphorylation-dependent K channels in nerve terminals [Abstract]. Soc Neurosci Abstr, 18, 72.
  19. Bielefeldt K, Rotter JL, Jackson MB (1991). Three potassium channels in rat nerve endings [Abstract]. Soc Neurosci Abstr, 17, 1324.
  20. Bielefeldt K, Reis HE (1990). [Hypoglycemia in type II diabetic patients]. [Abstract]. Med Klin (Munich), 85(3), 117-20.
  21. Bielefeldt K, Enck P, Krasemann T, Legler T, Erckenbrecht JF (1990). Effects of induced constipation on oro-cecal and whole gut transit time [Abstract]. Gastroenterol, 98, A327.
  22. Bielefeldt K, Bass P (1990). Sodium channel blockers affect the basic electric rhythm of the rat stomach in vivo [Abstract]. Gastroenterol, 98, A327.
  23. Enck P, Herdmann J, Boergermann K, Bielefeldt K, Erckenbrecht JF (1990). Up and down the spinal cord: Afferent and efferent innervation of the human external anal sphincter [Abstract]. Gastroenterol, 98, A348.
  24. Enck P, Gabor S, Bielefeldt K, vFerber L, Purrmann J, Tschoepe D (1990). How reliable are prevalence data for fecal incontinence? [Abstract]. Gastroenterol, 98, A3.
  25. Enck P, Musial F, Wallstein U, Lefalm C, Bielefeldt K, Erckenbrecht JF (1990). Perception of rectal distension: Influence of stimulus localisation and local and systemic anesthesia [Abstract]. Gastroenterol, 98, A348.
  26. Bielefeldt K, Bass P (1990). Sodium channel blockers alter gastric and jejunal basic electric rhythm (BER) in the rat [Abstract]. J Gastrointest Motility, 2, 132.
  27. Bielefeldt K, Frieling T, Mecklenbeck W, Berges W (1989). [Diagnosis of achalasia--comparison of methods for the evaluation of severity]. [Abstract]. Z Gastroenterol, 27(8), 421-5.
  28. Bielefeldt K, Reis HE (1989). [Autonomic neuropathy in diabetes mellitus, chronic renal failure and liver cirrhosis]. [Abstract]. Med Klin (Munich), 84(2), 72-6.
  29. Bielefeldt K, Erckenbrecht JF, Berges W, Strohmeyer G, Wienbeck M (1989). Achalasie-epidemiologische, anamnestische und manometrische Daten bei 289 Patienten (Achalasia-epidemiology, personal history, and manometry of 289 patients) [Abstract]. Klin Wochenschr, 67(S16), 42 (In German).
  30. Bielefeldt K, Reis HE (1989). Crohn-Aktivitaetsindizes-Hilfe oder Verwirrung? (Activity indices in Crohn's diseases-help or confusion?) [Abstract]. Klin Wochenschr, 67(S16), 232 (In German).
  31. Bielefeldt K, Reis HE (1989). Medikamentoese Nebenwirkungen bei Krankenhauseinweisung (Drug-induced side effects at hospitalization) [Abstract]. Med Welt, 40, 1008 (In German).
  32. Bielefeldt K, Enck P, Erckenbrecht JF (1989). Sensible Innervation bei anorektalen Funktionsstoerungen (Sensory innervation and anorectal dysfunction) [Abstract]. Med Welt, 40, 1040 (In German).
  33. Bielefeldt K, Enck P, Erckenbrecht JF (1989). Anorektale Sensibilitaet als Faktor der Kontinenzerhaltung (Anorectal sensitivity as a factor in the maintenance of continence) [Abstract]. Z Gastroenterologie, 27, 514 (In German).
  34. Bielefeldt K, Erckenbrecht JF, Berges W (1989). Manometrie bei oesophagealer Dysphagie-notwendige Diagnostik oder Kostentreiber (Manometry and functional dysphagia-necessary or expensive?) [Abstract]. Z Gastroenterologie, 27, 515 (In German).
  35. Bielefeldt K, Berges W (1989). Abdominelle Sonographie bei Dysphagie (Abdominal ultrasound in dysphagia) [Abstract]. Ultraschall, S1, 88 (In German).
  36. Bielefeldt K, Erckenbrecht JF (1989). Chronische Diarrhoe-neue histologische Differentialdiagnosen (Chronic diarrhea-new histological differential diagnosis) [Abstract]. Dtsch Med Wochenschr, 114, 1940-41.
  37. Bielefeldt K, Enck P, Erckenbrecht JF, Berges W (1989). Achalasia-not only a motor disorder of the lower esophageal sphincter [Abstract]. Gastroenterol, 96, A44.
  38. Enck P, Bielefeldt K, Erckenbrecht JF (1989). Age and sex and anorectal manometry in incontinence and continence [Abstract]. Gastroenterol, 96, A140.
  39. Bielefeldt K (1988). Haeufigkeit fokaler Milzlaesionen bei der Sonographie (Prevalence of focal lesion of the spleen during ultrasound examination) [Abstract]. Med Welt, 39, 497 (In German).
  40. Beckers B, Bielefeldt K, Reis HE (1988). Campylobacter pylori in Antrumbiopsien (Campylobacter pylori in antral biopsies) [Abstract]. Med Welt, 39, 501 (In German).
  41. Bielefeldt K, Reis HE (1988). Hypoglykaemie-ein Problem bei Typ-II-Diabetikern? (Hypoglycemia-a problem in type-2 diabetes?) [Abstract]. Akt Endokrin Stoffw, 9, 132 (In German).
  42. Bielefeldt K, Beckers B, Reis HE (1988). Diagnostik des antralen Campylobacter-Befalls-Methodische Probleme (Diagnosis of antral Campylobacter-methodological problems) [Abstract]. Z Gastroenterologie, 26, 490 (In German).
  43. Bielefeldt K, Reis HE (1988). Milzherde bei der abdominellen Sonographie (Focal spleen lesions during ultrasound investigations) [Abstract]. Ultraschall, 1(S), 61 (In German).
  44. Bielefeldt K, Reis HE (1988). Sonographische Gallenwegsbefunde nach endoskopischer Papillotomie und Konkrementextraktion (Sonographic appearance of the biliary system after papillotomy) [Abstract]. Ultraschall, 1(S), 92 (In German).
  45. Bielefeldt K, Reis HE (1987). Die Gallenblasenkontraktion bei Patienten mit autonomer Neuropathie (Gallbladder motility in patients with autonomic neuropathy) [Abstract]. Med Welt, 38, 673 (In German).
  46. Bielefeldt K, Reis HE (1987). Die differentialdiagnostische Bedeutung der hepatobiliaeren Swquenzszintigraphie bei extrahepatischen Gallenwegsobstruktionen (The relevance of hepatobiliary scintigraphy in extrahepatic cholestasis) [Abstract]. Med Welt, 38, 678-9 (In German).
  47. Bielefeldt K, Reis HE (1987). Die Gallenblasenkontraktion bei Patienten mit autonomer Neuropathie (Gallbladder motility in patients with autonomic neuropathy) [Abstract]. Akt Endokrin Stoffw, 8, 70 (In German).
  48. Bielefeldt K, Reis HE (1987). Palliative Chemotherapie von Malignomen des Pankreas und des biliaeren Systems (Palliative chemotherapy of pancreatic and biliary cancer) [Abstract]. Med Welt, 38, 1630 (In German).
  49. Bielefeldt K, Reis HE (1987). Hypoglykaemie bei Typ-II-Diabetikern-Haeufigkeit und Patientenwissen in einem unselektierten Patientengut (Hypoglycemia in type-e diabetics-incidence and patient knowledge) [Abstract]. Med Welt, 38, 634 (In German).
  50. Bielefeldt K, Korsten FW, Brandt A, Deux A, Reis HE (1986). Was vermag die hepatobiliaere Swquenzszintigraphie im Rahmen der gastroenterologischen Diagnostik? (What is the role of hepatobiliary scintigraphy in gastroenterological decision making?) [Abstract]. Gastro-Entero-Hepatologie, A:92 (In German).
  51. Bielefeldt K, Reis HE (1986). Die benigne Papillenstenose-Diagnose und Therapie eines umstrittenen Krankheitsbildes (The benign stenosis of the papilla Vateri-diagnosis and therapy of a controversial disease) [Abstract]. Med Welt, 37, 1539-40 (In German).
  52. Korsten FW, Bielefeldt K, Reis HE (1985). Palliation des malignen Verschlussikterus durch PTD und zytostatische Chemotherapie (Palliative therapy of malign extrahepatic cholestasis by PTD and chemotherapy) [Abstract]. Z Gastroenterologie, 23, 462 (In German).

Other

  1. Nusrat S, Mahmood S, Bitar H, Tierney WM, Bielefeldt K, Madhoun MF (2015). Erratum to: The Impact of Chronic Opioid Use on Colonoscopy Outcomes. Dig Dis Sci (60(9), p. 2850). United States.
  2. Bielefeldt K (1993). Perspectives of a German in an American Graduate School. Professional Scholars (2(5), pp. 5-7).
  3. Bielefeldt K (1993). Images of Science in Germany and the U.S. Professional Scholars (2(10), pp. 7-8).

Global Impact

Education History

Research Fellow Heinrich Heine University Düsseldorf
Gastroenterology
Research Fellow
Residency Krankenhaus Maria-Hilf GmbH
Internal Medicine
Resident
Professional Medical Rheinisch-Westfälische Technische Hochschule Aachen
Medicine
M.D.

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