Eleni Tseliou

Eleni Tseliou, MD, PhD

Languages spoken: English

  • Dr. Tseliou is an Assistant Professor of Medicine in the tenure track appointed to the Division of Cardiology at the University of Utah (UU). Dr. Tseliou received her MD and PhD at University of Athens in Greece and completed her post doctoral fellowship at Cedars Sinai Medical Center and her Internal Medicine, Cardiovascular and Advanced Heart Failure and Transplantation training at the UU. Dr. Tseliou is NIH funded and interested in studying metabolism in heart failure and cardiovascular diseases. Dr. Tseliou’s clinical interests also include care of patients with severe congestive heart failure including the use of mechanical circulatory support devices and cardiac transplantation.

    Specialties

    Board Certification

    American Board of Internal Medicine (Internal Medicine)
    American Board of Internal Medicine (Sub: Cardiovascular Disease)
    Educational Commission for Foreign Medical Graduates
    National Board of Echocardiography

  • Dr. Tseliou is an Assistant Professor of Medicine in the tenure track appointed to the Division of Cardiology at the University of Utah (UU). Dr. Tseliou received her MD and PhD at University of Athens in Greece and completed her post doctoral fellowship at Cedars Sinai Medical Center and her Internal Medicine, Cardiovascular and Advanced Heart Failure and Transplantation training at the UU. Dr. Tseliou is NIH funded and interested in studying metabolism in heart failure and cardiovascular diseases. Dr. Tseliou’s clinical interests also include care of patients with severe congestive heart failure including the use of mechanical circulatory support devices and cardiac transplantation.

    Board Certification and Academic Information

    Academic Departments Internal Medicine -Primary
    Academic Divisions Cardiovascular Medicine
    Board Certification
    American Board of Internal Medicine (Internal Medicine)
    American Board of Internal Medicine (Sub: Cardiovascular Disease)
    Educational Commission for Foreign Medical Graduates
    National Board of Echocardiography

    Education history

    Fellowship Advanced Heart Failure, Transplant Cardiology and Mechanical Circulatory Support - University of Utah Spencer Fox Eccles School of Medicine Fellow
    Cardiovascular Diseases - University of Utah Spencer Fox Eccles School of Medicine Fellow
    Residency Internal Medicine - University of Utah School of Medicine Resident
    Internal Medicine - Alexandra Hospital Resident
    Postdoctoral Fellowship Cedars-Sinai Medical Center Postdoctoral Research Fellow
    University of Athens School of Medicine Ph.D.
    Professional Medical Medicine - University of Athens School of Medicine M.D.

    Selected Publications

    Journal Article

    1. Drakos SG, Badolia R, Makaju A, Kyriakopoulos CP, Wever-Pinzon O, Tracy CM, Bakhtina A, Bia R, Parnell T, Taleb I, Ramadurai DKA, Navankasattusas S, Dranow E, Hanff TC, Tseliou E, Shankar TS, Visker J, Hamouche R, Stauder EL, Caine WT, Alharethi R, Selzman CH, Franklin S (2022). Distinct Transcriptomic and Proteomic Profile Specifies Patients Who Have Heart Failure With Potential of Myocardial Recovery on Mechanical Unloading and Circulatory Support. Circulation, 147(5), 409-424.
    2. Middleton RC, Rogers RG, De Couto G, Tseliou E, Luther K, Holewinski R, Soetkamp D, Van Eyk JE, Antes TJ, Marbn E (2018). Newt cells secrete extracellular vesicles with therapeutic bioactivity in mammalian cardiomyocytes. J Extracell Vesicles, 7(1), 1456888.
    3. Gallet R, Dawkins J, Valle J, Simsolo E, de Couto G, Middleton R, Tseliou E, Luthringer D, Kreke M, Smith RR, Marbn L, Ghaleh B, Marbn E (2015). Exosomes secreted by cardiosphere-derived cells reduce scarring, attenuate adverse remodelling, and improve function in acute and chronic porcine myocardial infarction. Eur Heart J, 38(3), 201-211.
    4. Reich H, Tseliou E, de Couto G, Angert D, Valle J, Kubota Y, Luthringer D, Mirocha J, Sun B, Smith RR, Marbn L, Marbn E (2016). Repeated transplantation of allogeneic cardiosphere-derived cells boosts therapeutic benefits without immune sensitization in a rat model of myocardial infarction. J Heart Lung Transplant, 35(11), 1348-1357.
    5. Kanazawa H, Tseliou E, Dawkins JF, De Couto G, Gallet R, Malliaras K, Yee K, Kreke M, Valle I, Smith RR, Middleton RC, Ho CS, Dharmakumar R, Li D, Makkar RR, Fukuda K, Marbn L, Marbn E (2016). Durable Benefits of Cellular Postconditioning: Long-Term Effects of Allogeneic Cardiosphere-Derived Cells Infused After Reperfusion in Pigs with Acute Myocardial Infarction. J Am Heart Assoc, 5(2).
    6. Tseliou E, Kanazawa H, Dawkins J, Gallet R, Kreke M, Smith R, Middleton R, Valle J, Marbn L, Kar S, Makkar R, Marbn E (2016). Widespread Myocardial Delivery of Heart-Derived Stem Cells by Nonocclusive Triple-Vessel Intracoronary Infusion in Porcine Ischemic Cardiomyopathy: Superior Attenuation of Adverse Remodeling Documented by Magnetic Resonance Imaging and Histology. PLoS One, 11(1), e0144523.
    7. Gallet R, de Couto G, Simsolo E, Valle J, Sun B, Liu W, Tseliou E, Zile MR, Marbn E (2016). Cardiosphere-derived cells reverse heart failure with preserved ejection fraction (HFpEF) in rats by decreasing fibrosis and inflammation. JACC Basic Transl Sci, 1(1-2), 14-28.
    8. Tseliou E, Fouad J, Reich H, Slipczuk L, de Couto G, Aminzadeh M, Middleton R, Valle J, Weixin L, Marbn E (2015). Fibroblasts Rendered Antifibrotic, Antiapoptotic, and Angiogenic by Priming With Cardiosphere-Derived Extracellular Membrane Vesicles. J Am Coll Cardiol, 66(6), 599-611.
    9. de Couto G, Liu W, Tseliou E, Sun B, Makkar N, Kanazawa H, Arditi M, Marbn E (2015). Macrophages mediate cardioprotective cellular postconditioning in acute myocardial infarction. J Clin Invest, 125(8), 3147-62.
    10. Gallet R, Tseliou E, Dawkins J, Middleton R, Valle J, Angert D, Reich H, Luthringer D, Kreke M, Smith R, Marbn L, Marbn E (2015). Intracoronary delivery of self-assembling heart-derived microtissues (cardiospheres) for prevention of adverse remodeling in a pig model of convalescent myocardial infarction. Circ Cardiovasc Interv, 8(5).
    11. Aminzadeh MA, Tseliou E, Sun B, Cheng K, Malliaras K, Makkar RR, Marbn E (2014). Therapeutic efficacy of cardiosphere-derived cells in a transgenic mouse model of non-ischaemic dilated cardiomyopathy. Eur Heart J, 36(12), 751-62.
    12. Diakos NA, Pozios I, Katsaros L, Vakrou S, Sventzouri S, Michelinakis N, Tseliou E, Bonios M, Malliaras K, Papalois A, Anastasiou-Nana M, Terrovitis JV (2015). Afterload-induced left ventricular diastolic dysfunction during myocardial ischaemia and reperfusion. Exp Physiol, 100(3), 288-301.
    13. Yee K, Malliaras K, Kanazawa H, Tseliou E, Cheng K, Luthringer DJ, Ho CS, Takayama K, Minamino N, Dawkins JF, Chowdhury S, Duong DT, Seinfeld J, Middleton RC, Dharmakumar R, Li D, Marbn L, Makkar RR, Marbn E (2014). Allogeneic cardiospheres delivered via percutaneous transendocardial injection increase viable myocardium, decrease scar size, and attenuate cardiac dilatation in porcine ischemic cardiomyopathy. PLoS One, 9(12), e113805.
    14. Tseliou E, Terrovitis JV, Kaldara EE, Ntalianis AS, Repasos E, Katsaros L, Margari ZJ, Matsouka C, Toumanidis S, Nanas SN, Nanas JN (2014). Red blood cell distribution width is a significant prognostic marker in advanced heart failure, independent of hemoglobin levels. Hellenic J Cardiol, 55(6), 457-61.
    15. Samartzis L, Dimopoulos S, Manetos C, Agapitou V, Tasoulis A, Tseliou E, Pozios I, Kaldara E, Terrovitis J, Nanas S (2014). Neuroticism personality trait is associated with Quality of Life in patients with Chronic Heart Failure. World J Cardiol, 6(10), 1113-21.
    16. Nguyen C, Fan Z, Xie Y, Dawkins J, Tseliou E, Bi X, Sharif B, Dharmakumar R, Marbn E, Li D (2014). In vivo contrast free chronic myocardial infarction characterization using diffusion-weighted cardiovascular magnetic resonance. J Cardiovasc Magn Reson, 16(1), 68.
    17. Malliaras K, Ibrahim A, Tseliou E, Liu W, Sun B, Middleton RC, Seinfeld J, Wang L, Sharifi BG, Marbn E (2014). Stimulation of endogenous cardioblasts by exogenous cell therapy after myocardial infarction. EMBO Mol Med, 6(6), 760-77.
    18. Tseliou E, de Couto G, Terrovitis J, Sun B, Weixin L, Marbn L, Marbn E (2014). Angiogenesis, cardiomyocyte proliferation and anti-fibrotic effects underlie structural preservation post-infarction by intramyocardially-injected cardiospheres. PLoS One, 9(2), e88590.
    19. Tseliou E, Reich H, de Couto G, Terrovitis J, Sun B, Liu W, Marbn E (2014). Cardiospheres reverse adverse remodeling in chronic rat myocardial infarction: roles of soluble endoglin and Tgf-β signaling. Basic Res Cardiol, 109(6), 443.
    20. Malliaras K, Smith RR, Kanazawa H, Yee K, Seinfeld J, Tseliou E, Dawkins JF, Kreke M, Cheng K, Luthringer D, Ho CS, Blusztajn A, Valle I, Chowdhury S, Makkar RR, Dharmakumar R, Li D, Marbn L, Marbn E (2013). Validation of contrast-enhanced magnetic resonance imaging to monitor regenerative efficacy after cell therapy in a porcine model of convalescent myocardial infarction. Circulation, 128(25), 2764-75.
    21. Dimopoulos S, Tzanis G, Manetos C, Tasoulis A, Mpouchla A, Tseliou E, Vasileiadis I, Diakos N, Terrovitis J, Nanas S (2013). Peripheral muscle microcirculatory alterations in patients with pulmonary arterial hypertension: a pilot study. Respir Care, 58(12), 2134-41.
    22. Tseliou E, Pollan S, Malliaras K, Terrovitis J, Sun B, Galang G, Marbn L, Luthringer D, Marbn E (2013). Allogeneic cardiospheres safely boost cardiac function and attenuate adverse remodeling after myocardial infarction in immunologically mismatched rat strains. J Am Coll Cardiol, 61(10), 1108-19.
    23. Malliaras K, Zhang Y, Seinfeld J, Galang G, Tseliou E, Cheng K, Sun B, Aminzadeh M, Marbn E (2013). Cardiomyocyte proliferation and progenitor cell recruitment underlie therapeutic regeneration after myocardial infarction in the adult mouse heart. EMBO Mol Med, 5(2), 191-209.
    24. Terrovitis J, Zotos P, Kaldara E, Diakos N, Tseliou E, Vakrou S, Kapelios C, Chalazonitis A, Nanas S, Toumanidis S, Kontoyannis D, Karga E, Nanas J (2012). Bone mass loss in chronic heart failure is associated with secondary hyperparathyroidism and has prognostic significance. Eur J Heart Fail, 14(3), 326-32.
    25. Cheng K, Malliaras K, Shen D, Tseliou E, Ionta V, Smith J, Galang G, Sun B, Houde C, Marbn E (2011). Intramyocardial injection of platelet gel promotes endogenous repair and augments cardiac function in rats with myocardial infarction. J Am Coll Cardiol, 59(3), 256-64.
    26. Dimopoulos S, Diakos N, Tseliou E, Tasoulis A, Mpouchla A, Manetos C, Katsaros L, Drakos S, Terrovitis J, Nanas S (2011). Chronotropic incompetence and abnormal heart rate recovery early after left ventricular assist device implantation. Pacing Clin Electrophysiol, 34(12), 1607-14.
    27. Bouchla A, Karatzanos E, Dimopoulos S, Tasoulis A, Agapitou V, Diakos N, Tseliou E, Terrovitis J, Nanas S (2010). The addition of strength training to aerobic interval training: effects on muscle strength and body composition in CHF patients. J Cardiopulm Rehabil Prev, 31(1), 47-51.

    Review

    1. Tseliou E, Lavine KJ, Wever-Pinzon O, Topkara VK, Meyns B, Adachi I, Zimpfer D, Birks EJ, Burkhoff D, Drakos SG (2022). Biology of myocardial recovery in advanced heart failure with long-term mechanical support. [Review]. J Heart Lung Transplant, 41(10), 1309-1323.
    2. Taleb I, Tseliou E, Fang JC, Drakos SG (2022). A Mechanical Bridge to Recovery as a Bridge to Discovery: Learning From Few and Applying to Many. [Review]. Circulation, 145(8), 562-564.

    Commentary

    1. Harrington J, Tseliou E, Shah S, Shah KS (2022). Paying Homage to the Power of Proteomics: Insights Into Obesity and Heart Failure From the HOMAGE Trial. J Card Fail, 28(5), 787-788.
    2. Bonios MJ, Tseliou E, Drakos SG (2020). Commentary: Major lessons from minor people: Beta blockers and cytokinesis in tetralogy of Fallot. J Thorac Cardiovasc Surg, 161(5), 1592-1593.

    Case Report

    1. Papachatzakis Y, Tseliou E, Tatouli I, Dialoupi I, Michas F, Papadopoulou E, Kousouris D, Kontogiannis S, Dimopoulos MA (2016). Colon Adenoma Implicating Myasthenia Gravis: A Case Report of a Patient with Postcolectomy Complications. Case Rep Neurol Med, 2016, 6297656.

    Letter

    1. Yin MY, Tandar A, Sharma V, Glotzbach JP, Shah RU, Dranow E, Tseliou E, Fang JC, Drakos SG, Welt FGP (2019). Left Ventricular Hemodynamic Changes During Transcatheter Aortic Valve Replacement Assessed by Real-Time Pressure-Volume Loops. [Letter to the editor]. JACC Cardiovasc Interv, 13(18), 2190-2192.
    2. Koudoumas D, Terrovitis J, Glentis P, Ntalianis A, Tsolakis E, Zannas AS, Tseliou E, Papalois A, Drakos S, Nanas JN (2016). Comparison of two biventricular infarct patterns with respect to the infarct burden required to induce cardiogenic shock: An experimental study. [Letter to the editor]. Hellenic J Cardiol, 58(4), 306-309.
    3. Agapitou V, Dimopoulos S, Mpouchla A, Samartzis L, Tseliou E, Kaldara E, Terrovitis J, Tasoulis A, Karga E, Nanas S (2010). Serum intact parathyroid hormone levels independently predict exercise capacity in stable heart failure patients. [Letter to the editor]. Int J Cardiol, 146(3), 462-4.

    Patent

    1. Marbán E, Tseliou E (2016). Urodele exosomes as therapeutic agents. U.S. Patent No. PCT/US2016/035561. Washington, D.C.:U.S. Patent and Trademark Office.
    2. Marbán E, Tseliou E (2015). Polarization of macrophages to a healing phenotype by cardiosphere-derived cells and by the exosomes secreted by such cells. U.S. Patent No. PCT/US2015/054301. Washington, D.C.:U.S. Patent and Trademark Office.
    3. Marbán E, Tseliou E (2014). U.S. Provisional Application. U.S. Patent No. 62/060,481. Washington, D.C.:U.S. Patent and Trademark Office.

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