Ryan A. Metcalf,
MD, CQA
Languages Spoken: English
Dr. Metcalf is Associate Medical Director of University Hospital Transfusion Services and ARUP Blood Services, Medical Director of the Immunohematology Reference Laboratory at ARUP, and Inpatient Chief Value Officer for the Department of Pathology. He completed a residency in Anatomic and Clinical Pathology and a fellowship in Transfusion Medicine at Stanford University and is board certified in these disciplines. He also has expertise in quality management and is a Certified Quality Auditor.
Dr. Metcalf practices transfusion medicine and his specific interests include data-driven approaches to patient blood management, quality management, and value-based healthcare. He was previously Assistant Professor at the University of Washington where he helped build a new FDA-registered hospital-based transfusion service laboratory. He was recruited to the University of Utah and ARUP in 2017. His research interests include the use of machine learning and data visualization techniques to predict and visualize patient blood management practice patterns and clinical patient outcomes. He is a member of the AABB Clinical Transfusion Medicine Committee, the AABB Patient Blood Management Standards Committee, and the College of American Pathologists (CAP) Transfusion, Apheresis, and Cellular Therapy Committee.
Specialties
Board Certification and Academic Information
| Academic Departments | Pathology
-
Assistant Professor (Clinical) |
| Academic Divisions | Clinical Pathology |
| Board Certification | American Board of Pathology (Anatomic & Clinical) American Board of Pathology (Sub: Blood Banking/Transfusion Medicine) National Board of Medical Examiners |
Dr. Metcalf is Associate Medical Director of University Hospital Transfusion Services and ARUP Blood Services, Medical Director of the Immunohematology Reference Laboratory at ARUP, and Inpatient Chief Value Officer for the Department of Pathology. He completed a residency in Anatomic and Clinical Pathology and a fellowship in Transfusion Medicine at Stanford University and is board certified in these disciplines. He also has expertise in quality management and is a Certified Quality Auditor.
Dr. Metcalf practices transfusion medicine and his specific interests include data-driven approaches to patient blood management, quality management, and value-based healthcare. He was previously Assistant Professor at the University of Washington where he helped build a new FDA-registered hospital-based transfusion service laboratory. He was recruited to the University of Utah and ARUP in 2017. His research interests include the use of machine learning and data visualization techniques to predict and visualize patient blood management practice patterns and clinical patient outcomes. He is a member of the AABB Clinical Transfusion Medicine Committee, the AABB Patient Blood Management Standards Committee, and the College of American Pathologists (CAP) Transfusion, Apheresis, and Cellular Therapy Committee.
Academic Locations
ARUP
801-585-6217
Board Certification and Academic Information
| Academic Departments | Pathology
-
Assistant Professor (Clinical) |
| Academic Divisions | Clinical Pathology |
| Board Certification | American Board of Pathology (Anatomic & Clinical) American Board of Pathology (Sub: Blood Banking/Transfusion Medicine) National Board of Medical Examiners |
Education History
| Fellowship | Stanford University School of Medicine Transfusion Medicine Fellow |
| Residency | Stanford University School of Medicine Anatomic and Clinical Pathology Resident |
| Professional Medical | University of California, Davis School of Medicine Medicine M.D. |
| Fellowship | Stanford University School of Medicine Pathology Predoctoral Fellow |
| Undergraduate | University of California, Santa Barbara Cell and Developmental Biology B.S. |
Selected Publications - Journal Articles
Journal Article
- Pagano MB, Allen ES, Dunbar NM, Goel R, Harm S, Hopkins CK, Jacobsen J, Lokhandwala PM, Metcalf RA, Raval JS, Schwartz J, Spinella PC, Storch E, Cohn CS (2020). Current Advances in Transfusion Medicine: A 2019 review of selected topics from the AABB Clinical Transfusion Medicine Committee. Transfusion.
- White SK, Schmidt RL, Walker BS, Metcalf RA (2020). Bacterial contamination rate of platelet components by primary culture: A systematic review and meta-analysis. Transfusion.
- Lim MY, Pagano MB, Metcalf RA (2020). Things we do for no reason: routinely prescribing transfusion premedication to prevent acute transfusion reactions. Journal of Hospital Medicine.
- Metcalf RA, White S, Potter S, Barney R, Hunter C, White M, Enniss T, Galaviz C, Reddy S, Wanner N, Schmidt RL, Blaylock R (2019). The association of inpatient blood utilization and diagnosis related group weight: implications for risk-adjusted benchmarking. Transfusion, 59(7), 2316-2323.
- Gavva C, Barroso J, Gernsheimer T, Metcalf RA, Warner P, Pagano MB (2019). Response to Random Apheresis Platelets versus HLA-Selected Platelets versus Pooled Platelets in HLA-sensitized Patients. Transfusion, 59(7), 2276-2281.
- Pagano MB, Katchatag B, Khoobyari S, Van Gerwen M, Sen N, Haley R, Gernsheimer T, Hess JR, Metcalf RA (2019). Evaluating Safety and Cost-Effectiveness of Platelets Stored in Additive Solution (PAS-F) as a Hemolysis Risk Mitigation Strategy. Transfusion, 59(4), 1246-1251.
- Metcalf RA, Calvaresi E, Tonna JE, Blaylock R, Pearson L (2019). Severe Hemolysis Following Extracorporeal Right Ventricular Assist Device Placement. Transfusion, 59(4), 1178-1179.
- Murphy C, Parakh R, Metcalf RA, Pagano MB (2018). Transfusion Associated Chest Pain. Transfusion.
- Metcalf RA, Khan J, Andrews J, Mayock D, Billimoria Z, Pagano MB (2018). Severe ABO Hemolytic Disease of the Newborn Requiring Exchange Transfusion. J Pediatr Hematol Oncol.
- Metcalf RA, Pagano MB, Hess JR, Reyes J, Perkins JD, Montenovo MI (2018). A Data-Driven Patient Blood Management Strategy in Liver Transplantation. Vox Sang.
- Corean J, Al-Tigar R, Pysher T, Blaylock R, Metcalf RA (2018). Quality improvement after multiple fatal transfusion-transmitted bacterial infections. Am J Clin Pathol, 149(4), 293-299.
- Hess JR, Ramos PJ, Sen NE, Cruz-Cody VG, Tuott EE, Louzon MJ, Bulger EM, Arbabi S, Pagano MB, Metcalf RA (2018). Quality management of a massive transfusion protocol. Transfusion.
- Mays, JA, Greene DN, Metcalf RA, Pagano MB (2018). Transfusion support for transgender men of childbearing age. Transfusion.
- Pagano MB, Metcalf RA, Hess JR, Reyes J, Perkins JD, Montenovo MI (2018). A high plasma: red blood cell transfusion ratio during liver transplantation is associated with decreased blood utilization. Vox Sang.
- Hess JR, Hayden BK, Cruz-Cody VG, Louzon MJ, Tuott EE, Sen NE, Gary R, Ramos PJ, Daniel-Johnson JA, Metcalf RA, Pagano MB (2017). Building a new transfusion service. Am J Clin Pathol.
- Metcalf RA, Bakhtary S, Goodnough LT, Andrews J (2016). Clinical Pattern in Hypotensive Transfusion Reactions. Anesth Analg, 123(2), 268-73.
- Metcalf RA, Baker SA, Goodnough LT, Shah N (2016). Transportation Cooler Interventions Reduce Plasma and RBC Product Wastage. Am J Clin Pathol, 146(1), 18-24.
- Hartmann S, Winkelmann R, Metcalf RA, Treetipsatit J, Warnke RA, Natkunam Y, Hansmann ML (2015). Immunoarchitectural patterns of progressive transformation of germinal centers with and without nodular lymphocyte-predominant Hodgkin lymphoma. Hum Pathol, 46(11), 1655-61.
- Metcalf RA, Wang L, Deos PH, Chock E, Warnke RA, Natkunam Y (2015). Extracavitary Primary Effusion Lymphoma Presenting in a Lymph Node Without Lymphomatous Effusions. Hum Pathol (N Y), 2(2), 36-41.
- Treetipsatit J, Metcalf RA, Warnke RA, Natkunam Y (2015). Large B-cell lymphoma with T-cell-rich background and nodules lacking follicular dendritic cell meshworks: description of an insufficiently recognized variant. Hum Pathol, 46(1), 74-83.
- Metcalf RA, Monabati A, Vyas M, Roncador G, Gualco G, Bacchi CE, Younes SF, Natkunam Y, Freud AG (2014). Myeloid cell nuclear differentiation antigen is expressed in a subset of marginal zone lymphomas and is useful in the differential diagnosis with follicular lymphoma. Hum Pathol, 45(8), 1730-6.
- Metcalf RA, Bashey S, Wysong A, Kim J, Kim YH, Gratzinger D (2013). Intravascular ALK-negative anaplastic large cell lymphoma with localized cutaneous involvement and an indolent clinical course: toward recognition of a distinct clinicopathologic entity. Am J Surg Pathol, 37(4), 617-23.
- Sankaran VG, Ludwig LS, Sicinska E, Xu J, Bauer DE, Eng JC, Patterson HC, Metcalf RA, Natkunam Y, Orkin SH, Sicinski P, Lander ES, Lodish HF (2012). Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number. Genes Dev, 26(18), 2075-87.
- Metcalf RA, Zhao S, Anderson MW, Lu ZS, Galperin I, Marinelli RJ, Cherry AM, Lossos IS, Natkunam Y (2010). Characterization of D-cyclin proteins in hematolymphoid neoplasms: lack of specificity of cyclin-D2 and D3 expression in lymphoma subtypes. Mod Pathol, 23(3), 420-33.
- Walker BS, Schmidt RL, Fisher MA, White SK, Blaylock RC, Metcalf RA (2020). The comparative safety of bacterial risk control strategies for platelet components: A simulation study. Transfusion.
- Walker BS, White SK, Schmidt RL, Metcalf RA (2020). Residual bacterial detection rates following primary culture as determined by secondary culture and rapid testing in platelet components: a systematic review and meta-analysis. Transfusion.
Video/Film/CD/Web/Podcast
- Metcalf RA (2020). Patient Blood Management [Video]. Clinical Chemistry Pearls.
- Metcalf RA (2017). Blood Utilization and The Transfusion Committee [Web]. Clincial Chemistry Pearls of Laboratory Medicine..