Laurie W. Leclair,
MD
Languages Spoken: English
Dr. Leclair specializes in lung transplantation and cystic fibrosis. She completed her medical degree at Tufts University, followed by residency at the University of Colorado and a fellowship at Yale University. She joined the faculty at the University of Utah in 2019 from the University of Vermont. In addition to her clinical work she an Assistant Dean of Curriculum and is responsible for the oversight of all coursework within the clinical curriculum.
Clinical Locations
801-581-2000
Lung Transplant, Clinic 3
801-585-3697
Specialties
Board Certification and Academic Information
| Academic Departments | Internal Medicine
-
Professor (Clinical) |
| Academic Divisions | Pulmonary |
| Board Certification | American Board of Internal Medicine American Board of Internal Medicine (Sub: Critical Care Medicine) American Board of Internal Medicine (Sub: Pulmonary Disease) |
Patient Rating
The Patient Rating score is an average of all responses to care provider related questions on our nationally-recognized Press Ganey Patient Satisfaction Survey.
Responses are measured on a scale of 1 to 5 with 5 being the best score.
Likelihood of recommending care provider
4.8/ 5
Care provider's explanation of condition/problem
4.8/ 5
Care provider's effort to include me in decisions
4.8/ 5
Wait time at clinic
4.5/ 5
Care provider's concern for questions & worries
4.8/ 5
Patient Comments
Patient comments are gathered from our Press Ganey Patient Satisfaction Survery and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
UofU Patient
February 14, 2022
SUGAR HOUSE HEALTH CENTER
They are great to work with!!
UofU Patient
September 15, 2021
SUGAR HOUSE HEALTH CENTER
Doctor was nice and professional; however, I did not feel my opinions regarding my health were valued.
UofU Patient
June 12, 2021
UH HOSPITALS AND CLINICS
the whole transplant team is top notch
UofU Patient
June 03, 2021
UH HOSPITALS AND CLINICS
Dr. Leclair spent a lot of time talking about my questions and helping me have all the information I need.
UofU Patient
April 04, 2021
UH HOSPITALS AND CLINICS
I have already highly recommended U of U hospital to many people!
UofU Patient
March 14, 2021
SUGAR HOUSE HEALTH CENTER
Everybody I met with was amazing.
Dr. Leclair specializes in lung transplantation and cystic fibrosis. She completed her medical degree at Tufts University, followed by residency at the University of Colorado and a fellowship at Yale University. She joined the faculty at the University of Utah in 2019 from the University of Vermont. In addition to her clinical work she an Assistant Dean of Curriculum and is responsible for the oversight of all coursework within the clinical curriculum.
Academic Locations
Maxwell M. Wintrobe Research and Education Building
801-581-7806
Board Certification and Academic Information
| Academic Departments | Internal Medicine
-
Professor (Clinical) |
| Academic Divisions | Pulmonary |
| Board Certification | American Board of Internal Medicine American Board of Internal Medicine (Sub: Critical Care Medicine) American Board of Internal Medicine (Sub: Pulmonary Disease) |
Education History
| Postdoctoral Fellowship | Yale School of Medicine Pulmonary and Critical Care Medicine Postdoctoral Fellow, 2002 |
| Internship/Residency | University of Colorado Health Sciences Center Internal Medicine Intern/Resident, 1999 |
| Professional Medical | Tufts University School of Medicine Medicine M.D., 1996 |
| Undergraduate | University of Vermont Chemistry B.A., 1992 |
Selected Publications - Journal Articles
Journal Article
- Amarbir S Gill, Abigail Pulsipher, Jorgen S Sumsion, Gretchen M Oakley, Laurie W Leclair, Heather Howe, Richard R Orlandi, Jeremiah A Alt (2021). Transcriptional Changes in Chronic Rhinosinusitis with Asthma Favor a Type 2 Molecular Endotype Independent of Polyp Status. J Asthma Allergy, 14, 405-13.
- Gill AS, Pulsipher A, Sumsion JS, Oakley GM, Leclair LW, Howe H, Orlandi RR, Alt JA (2021). Transcriptional Changes in Chronic Rhinosinusitis with Asthma Favor a Type 2 Molecular Endotype Independent of Polyp Status. J Asthma Allergy, 14, 405-413.
- Leclair LW, Dawson M, Howe A, Hale S, Zelman E, Clouser R, Garrison G, Allen G (2018). A longitudinal interprofessional simulation curriculum for critical care teams: Exploring successes and challenges. J Interprof Care, 32(3), 386-390.
- Griswold KE, Bement JL, Teneback CC, Scanlon TC, Wargo MJ, Leclair LW (2014). Bioengineered lysozyme in combination therapies for Pseudomonas aeruginosa lung infections. Bioengineered, 5(2), 143-7.
- Anathy V, Aesif SW, Hoffman SM, Bement JL, Guala AS, Lahue KG, Leclair LW, Suratt BT, Cool CD, Wargo MJ, Janssen-Heininger YM (2014). Glutaredoxin-1 attenuates S-glutathionylation of the death receptor fas and decreases resolution of Pseudomonas aeruginosa pneumonia. Am J Respir Crit Care Med, 189(4), 463-74.
- Teneback CC, Scanlon TC, Wargo MJ, Bement JL, Griswold KE, Leclair LW (2013). Bioengineered lysozyme reduces bacterial burden and inflammation in a murine model of mucoid Pseudomonas aeruginosa lung infection. Antimicrob Agents Chemother, 57(11), 5559-64.
- Zhu J, Bean HD, Wargo MJ, Leclair LW, Hill JE (2013). Detecting bacterial lung infections: in vivo evaluation of in vitro volatile fingerprints. J Breath Res, 7(1), 016003.
- Entezari M, Weiss DJ, Sitapara R, Whittaker L, Wargo MJ, Li J, Wang H, Yang H, Sharma L, Phan BD, Javdan M, Chavan SS, Miller EJ, Tracey KJ, Mantell LL (2012). Inhibition of high-mobility group box 1 protein (HMGB1) enhances bacterial clearance and protects against Pseudomonas Aeruginosa pneumonia in cystic fibrosis. Mol Med, 18, 477-85.
- Neveu WA, Bernardo E, Allard JL, Nagaleekar V, Wargo MJ, Davis RJ, Iwakura Y, Whittaker LA, Rincon M (2011). Fungal allergen beta-glucans trigger p38 mitogen-activated protein kinase-mediated IL-6 translation in lung epithelial cells. Am J Respir Cell Mol Biol, 45(6), 1133-41.
- Wargo MJ, Gross MJ, Rajamani S, Allard JL, Lundblad LK, Allen GB, Vasil ML, Leclair LW, Hogan DA (2011). Hemolytic phospholipase C inhibition protects lung function during Pseudomonas aeruginosa infection. Am J Respir Crit Care Med, 184(3), 345-54.
- Goodwin M, Sueblinvong V, Eisenhauer P, Ziats NP, LeClair L, Poynter ME, Steele C, Rincon M, Weiss DJ (2011). Bone marrow-derived mesenchymal stromal cells inhibit Th2-mediated allergic airways inflammation in mice. Stem Cells, 29(7), 1137-48.
- Scanlon TC, Teneback CC, Gill A, Bement JL, Weiner JA, Lamppa JW, Leclair LW, Griswold KE (2010). Enhanced antimicrobial activity of engineered human lysozyme. ACS Chem Biol, 5(9), 809-18.
- Hodgkins SR, Ather JL, Paveglio SA, Allard JL, LeClair LA, Suratt BT, Boyson JE, Poynter ME (2010). NO2 inhalation induces maturation of pulmonary CD11c+ cells that promote antigenspecific CD4+ T cell polarization. Respir Res, 11, 102.
- Neveu WA, Allard JB, Dienz O, Wargo MJ, Ciliberto G, Whittaker LA, Rincon M (2009). IL-6 is required for airway mucus production induced by inhaled fungal allergens. J Immunol, 183(3), 1732-8.
- Suratt BT, Eisner MD, Calfee CS, Allard JB, Whittaker LA, Engelken DT, Petty JM, Trimarchi T, Gauthier L, Parsons PE (2009). Plasma granulocyte colony-stimulating factor levels correlate with clinical outcomes in patients with acute lung injury. Crit Care Med, 37(4), 1322-8.
- Allard JB, Rinaldi L, Wargo MJ, Allen G, Akira S, Uematsu S, Poynter ME, Hogan DA, Rincon M, Whittaker LA (2009). Th2 allergic immune response to inhaled fungal antigens is modulated by TLR-4-independent bacterial products. Eur J Immunol, 39(3), 776-88.
- Wargo MJ, Ho TC, Gross MJ, Whittaker LA, Hogan DA (2009). GbdR regulates Pseudomonas aeruginosa plcH and pchP transcription in response to choline catabolites. Infect Immun, 77(3), 1103-11.
- Pantano C, Ather JL, Alcorn JF, Poynter ME, Brown AL, Guala AS, Beuschel SL, Allen GB, Whittaker LA, Bevelander M, Irvin CG, Janssen-Heininger YM (2008). Nuclear factor-kappaB activation in airway epithelium induces inflammation and hyperresponsiveness. Am J Respir Crit Care Med, 177(9), 959-69.
- Bevelander M, Mayette J, Whittaker LA, Paveglio SA, Jones CC, Robbins J, Hemenway D, Akira S, Uematsu S, Poynter ME (2007). Nitrogen dioxide promotes allergic sensitization to inhaled antigen. J Immunol, 179(6), 3680-8.
- Paveglio SA, Allard J, Mayette J, Whittaker LA, Juncadella I, Anguita J, Poynter ME (2007). The tick salivary protein, Salp15, inhibits the development of experimental asthma. J Immunol, 178(11), 7064-71.
- Allard JB, Poynter ME, Marr KA, Cohn L, Rincon M, Whittaker LA (2006). Aspergillus fumigatus generates an enhanced Th2-biased immune response in mice with defective cystic fibrosis transmembrane conductance regulator. J Immunol, 177(8), 5186-94.
- Kostyk AG, Dahl KM, Wynes MW, Whittaker LA, Weiss DJ, Loi R, Riches DW (2006). Regulation of chemokine expression by NaCl occurs independently of cystic fibrosis transmembrane conductance regulator in macrophages. Am J Pathol, 169(1), 12-20.
- Whittaker L, Niu N, Temann UA, Stoddard A, Flavell RA, Ray A, Homer RJ, Cohn L (2002). Interleukin-13 mediates a fundamental pathway for airway epithelial mucus induced by CD4 T cells and interleukin-9. Am J Respir Cell Mol Biol, 27(5), 593-602.
- Whittaker LA, Cohn L (2002). Recent Concepts in the Pathogenesis and Treatment of Asthma. Clin Pulm Med, 9(3), 135-44.
- Cohn L, Whittaker L, Niu N, Homer RJ (2002). Cytokine regulation of mucus production in a model of allergic asthma. Novartis Found Symp, 248, 201-13; discussion 213-20, 277-82.
Review
- Leclair LW, Hogan DA (2010). Mixed bacterial-fungal infections in the CF respiratory tract. [Review]. Med Mycol, 48 Suppl 1, S125-32.
- Whittaker LA, Teneback C (2009). Atypical mycobacterial and fungal infections in cystic fibrosis. [Review]. Semin Respir Crit Care Med, 30(5), 539-46.
- Sueblinvong V, Whittaker LA (2007). Fertility and pregnancy: common concerns of the aging cystic fibrosis population. [Review]. Clin Chest Med, 28(2), 433-43.
- Sueblinvong V, Whittaker LA (2006). Management Issues in Women with Cystic Fibrosis. [Review]. 9(6), 24.
- Whittaker LA, Kaminsky D (2006). Respiratory Physiology in Extreme Environments. [Review]. Clin Pulm Med, 13(5), 282-8.
Case Report
- Whittaker LA, Bisognano JD (2001). Right-Sided Heart Failure and Severe Tricuspid Regurgitation After Mediastinal Radiation. Cardiovasc Rev Rep, 22(1), 23-5.
Editorial
Letter
- Gonzalez KD, Zuckerman JB, Sears EH, Prato BS, Guill M, Craig W, Milliard C, Parker E, Lever T, Griffin MM, Leclair LW (2017). Exploring probiotic use in a regional cystic fibrosis consortium. [Letter to the editor]. J Cyst Fibros, 17(2), e20-e21.
- Zuckerman JB, Clock SA, Prato BS, McDevitt JJ, Zhou JJ, Leclair LW, Lucas FL, Saiman L (2015). Air contamination with bacteria in cystic fibrosis clinics: implications for prevention strategies. [Letter to the editor]. Am J Respir Crit Care Med, 191(5), 598-601.
Other
- Gill AS, Smith KA, Meeks H, Oakley GM, Curtin K, Leclair L, Howe H, Orlandi RR, Alt JA (2021). Asthma increases long-term revision rates of endoscopic sinus surgery in chronic rhinosinusitis with and without nasal polyposis. Int Forum Allergy Rhinol (11(8), pp. 1197-1206). United States.
- Whittaker LA (2005). Recent Advances in Cystic Fibrosis. Pulmonary and Critical Care Update (19, Lesson 1).
- Whittaker LA, Kaminsky D, Irvin C (2004). Respiratory System in Extreme Environments. Pulmonary and Critical Care Update (17, Lesson 23).