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Specialties
Board Certification
American Board of Internal Medicine (Internal Medicine)Educational Commission for Foreign Medical GraduatesNational Board of Medical Examiners -
Board Certification and Academic Information
Academic Departments Internal Medicine -Primary Academic Divisions Public Health
Board Certification American Board of Internal Medicine (Internal Medicine)Educational Commission for Foreign Medical GraduatesNational Board of Medical ExaminersEducation history
Fellowship Pulmonary and Critical Care Medicine - University of Iowa Roy J. and Lucille A. Carver College of Medicine Fellow Internal Medicine - University of Iowa Roy J. and Lucille A. Carver College of Medicine Resident Selected Publications
Journal Article
- Vargas Buonfiglio LG, Vanegas Calderon OG, Cano M, Simmering JE, Polgreen PM, Zabner J, Gerke AK, Comellas AP (2020). Seasonal Antimicrobial Activity of the Airway: Post-Hoc Analysis of a Randomized Placebo-Controlled Double-Blind Trial. Nutrients, 12(9). (Read full article)
- Pezzulo AA, Tudas RA, Stewart CG, Buonfiglio LGV, Lindsay BD, Taft PJ, Gansemer ND, Zabner J (2019). HSP90 inhibitor geldanamycin reverts IL-13- and IL-17-induced airway goblet cell metaplasia. J Clin Invest, 129(2), 744-758. (Read full article)
- Vargas Buonfiglio LG, Borcherding JA, Frommelt M, Parker GJ, Duchman B, Vanegas Caldern OG, Fernandez-Ruiz R, Noriega JE, Stone EA, Gerke AK, Zabner J, Comellas AP (2018). Airway surface liquid from smokers promotes bacterial growth and biofilm formation via iron-lactoferrin imbalance. Respir Res, 19(1), 42. (Read full article)
- Li X, Vargas Buonfiglio LG, Adam RJ, Stoltz DA, Zabner J, Comellas AP (2017). Cystic Fibrosis Transmembrane Conductance Regulator Potentiation as a Therapeutic Strategy for Pulmonary Edema: A Proof-of-Concept Study in Pigs. Crit Care Med, 45(12), e1240-e1246. (Read full article)
- Vargas Buonfiglio LG, Mudunkotuwa IA, Abou Alaiwa MH, Vanegas Caldern OG, Borcherding JA, Gerke AK, Zabner J, Grassian VH, Comellas AP (2017). Effects of Coal Fly Ash Particulate Matter on the Antimicrobial Activity of Airway Surface Liquid. Environ Health Perspect, 125(7), 077003. (Read full article)
- Vargas Buonfiglio LG, Cano M, Pezzulo AA, Vanegas Calderon OG, Zabner J, Gerke AK, Comellas AP (2017). Effect of vitamin D(3) on the antimicrobial activity of human airway surface liquid: preliminary results of a randomised placebo-controlled double-blind trial. BMJ Open Respir Res, 4(1), e000211. (Read full article)
- Buonfiglio LG, Bagegni M, Borcherding JA, Sieren JC, Caraballo JC, Reger A, Zabner J, Li X, Comellas AP (2016). Protein Kinase Cζ Inhibitor Promotes Resolution of Bleomycin-Induced Acute Lung Injury. Am J Respir Cell Mol Biol, 55(6), 869-877. (Read full article)
- Li X, Tang XX, Vargas Buonfiglio LG, Comellas AP, Thornell IM, Ramachandran S, Karp PH, Taft PJ, Sheets K, Abou Alaiwa MH, Welsh MJ, Meyerholz DK, Stoltz DA, Zabner J (2016). Electrolyte transport properties in distal small airways from cystic fibrosis pigs with implications for host defense. Am J Physiol Lung Cell Mol Physiol, 310(7), L670-9. (Read full article)
- Gutierrez JA, Hannoush ZC, Vargas LG, Momany A, Garcia CC, Murray JC, Dunnwald M (2013). A Novel non-sense Mutation in Keratin 10 Causes a Familial Case of Recessive Epidermolytic Ichthyosis. Mol Genet Genomic Med, 1(2), 108-112. (Read full article)
Editorial
- Vargas Buonfiglio LG, Comellas AP (2020). Mechanism of ambient particulate matter and respiratory infections. J Thorac Dis, 12(3), 134-136. (Read full article)
Patent
- Comellas Freymond AP, Li X, Vargas Buonfiglio LG (2015). Lung injury repair and compositions and methods. U.S. Patent No. 20160120934. Washington, D.C.:U.S. Patent and Trademark Office.