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Amir M. Arain
Rating: 4.7 of 5
( out of 168 reviews )

Amir M. Arain, MD, MPH

Languages spoken: Arabic, Urdu, English

Clinical Locations

Primary Location

Clinical Neurosciences Center

175 North Medical Drive East
Salt Lake City , UT 84132
  • Dr. Amir M. Arain is a professor and an epileptologist that focuses on treatment of refractory epilepsy. He graduated from Dow Medical College, Karachi and did his Neurology residency and Epilepsy fellowship at Vanderbilt University. There he served on the faculty of Department of Neurology as an epileptologist from 2000-2018. He joined University of Utah in July 2018 and currently serves as chief of Epilepsy division.

    Dr. Arain has been involved in different research projects in epilepsy. He has done several antiepileptic drug trials including levetiracetam, oxcarbazepine, pregabalin, lacosemide, retigabine, brivaracetam, carisbamate, eslicarbazepine and cenobamate. He has published several peer reviewed research articles and has presented data in different scientific meetings. He has trained more than 100 fellows in epilepsy over the years. His interest is in seizure semiology, SUDEP, disparity of care in epilepsy and Geriatric epilepsy.

    Board Certification

    American Board of Clinical Neurophysiology
    American Board of Psychiatry & Neurology (Neurology)
    American Board of Psychiatry & Neurology (Sub: Clinical Neurophysiology)
    American Board of Psychiatry & Neurology (Sub: Epilepsy)

    Patient Rating

    Rating: 4.7 out of 5
    4.7 /5
    ( out of 168 reviews )

    The patient rating score is an average of all responses on our patient experience survey. The rating averages scores for all questions about care from our providers.

    The scale on which responses are measured is 1 to 5 with 5 being the best score.

    Patient Comments

    Patient comments are gathered from our patient experience survey and displayed in their entirety. For the convenience of our visitors, some patient comments have been translated from their original language into English while preserving their original meaning as accurately as possible. Patients are de-identified for confidentiality and patient privacy.

    December 17, 2025
    CLINICAL NEUROSCIENCES CENTER
    Rating: 5 out of 5

    Dr. Arain is always nice respectful and treats your care with the best he can and he explains everything to then at the end he always asks if we have questions before your appointment is overthats always good he's a great Neurologist

    December 09, 2025
    CLINICAL NEUROSCIENCES CENTER
    Rating: 5 out of 5

    Very knowledgeable and I feel confident he's prescribing the right medication to treat my epilepsy. It's a blessing I got in with this neurologist.

    November 22, 2025
    CLINICAL NEUROSCIENCES CENTER
    Rating: 5 out of 5

    I have full confidence in placing my health care needs in Dr. Arian's hands. [NAME REMOVED]

    November 20, 2025
    CLINICAL NEUROSCIENCES CENTER
    Rating: 5 out of 5

    The Most prestigious neurologist I've ever been around!!! Second too None!!!

    November 14, 2025
    CLINICAL NEUROSCIENCES CENTER
    Rating: 5 out of 5

    Nice person and Doctor

    November 08, 2025
    CLINICAL NEUROSCIENCES CENTER
    Rating: 5 out of 5

    Excellent Physician

    November 07, 2025
    CLINICAL NEUROSCIENCES CENTER
    Rating: 5 out of 5

    A caring and knowledgeable professional!

    November 06, 2025
    CLINICAL NEUROSCIENCES CENTER
    Rating: 5 out of 5

    Extremely knowledgeable and empathetic. Realistically shared in Medical decision making.

    October 29, 2025
    CLINICAL NEUROSCIENCES CENTER
    Rating: 5 out of 5

    Very knowledgeable and helpful.

  • Dr. Amir M. Arain is a professor and an epileptologist that focuses on treatment of refractory epilepsy. He graduated from Dow Medical College, Karachi and did his Neurology residency and Epilepsy fellowship at Vanderbilt University. There he served on the faculty of Department of Neurology as an epileptologist from 2000-2018. He joined University of Utah in July 2018 and currently serves as chief of Epilepsy division.

    Dr. Arain has been involved in different research projects in epilepsy. He has done several antiepileptic drug trials including levetiracetam, oxcarbazepine, pregabalin, lacosemide, retigabine, brivaracetam, carisbamate, eslicarbazepine and cenobamate. He has published several peer reviewed research articles and has presented data in different scientific meetings. He has trained more than 100 fellows in epilepsy over the years. His interest is in seizure semiology, SUDEP, disparity of care in epilepsy and Geriatric epilepsy.

    Board Certification and Academic Information

    Academic Departments Neurology -Professor
    Board Certification
    American Board of Clinical Neurophysiology
    American Board of Psychiatry & Neurology (Neurology)
    American Board of Psychiatry & Neurology (Sub: Clinical Neurophysiology)
    American Board of Psychiatry & Neurology (Sub: Epilepsy)

    Education history

    Graduate Training Epidemiology, Biostatistics, Clinical Research Design, etc - Vanderbilt University M.P.H.
    Fellowship Epilepsy/Neurophysiology - Vanderbilt University Medical Center Clinical Fellow
    Chief Resident Neurology - Vanderbilt University Medical Center Chief Resident
    Residency Neurology - Vanderbilt University Medical Center Resident
    Internship Internal Medicine - McLaren Flint Intern
    Professional Medical Medicine, Surgery - Dow Medical College of the University of Karachi M.B.B.S.

    Selected Publications

    Journal Article

    1. Campbell JM, Davis TS, Nesterovich Anderson D, Arain A, Davis ZW, Inman CS, Smith EH, Rolston JD (2025). Macroscale traveling waves evoked by single-pulse stimulation of the human brain. J Neurosci, 45(21). (Read full publication)
    2. Campbell JM, Cowan RL, Wahlstrom KL, Hollearn MK, Jensen D, Davis T, Rahimpour S, Shofty B, Arain A, Rolston JD, Hamann S, Wang S, Eisenman LN, Swift J, Xie T, Brunner P, Manns JR, Inman CS, Smith EH, Willie JT (2025). Human single-neuron activity is modulated by intracranial theta burst stimulation of the basolateral amygdala. bioRxiv. (Read full publication)
    3. Arain AM, Mirro EA, Brown D, Peters A, Newman B, Richards S, Rolston JD (2023). Long-Term Intracranial EEG Lateralization of Epileptogenicity in Patients With Confirmed or Suspected Bilateral Mesial Temporal Lobe Onsets During Epilepsy Surgical Evaluation. J Clin Neurophysiol, 41(6), 522-529. (Read full publication)
    4. Campbell JM, Davis TS, Anderson DN, Arain A, Davis Z, Inman CS, Smith EH, Rolston JD (2024). Macroscale traveling waves evoked by single-pulse stimulation of the human brain. bioRxiv. (Read full publication)
    5. Yearley AG, Smith EH, Davis TS, Anderson D, Arain AM, Rolston JD (2024). Interictal discharge traveling waves recorded from stereoelectroencephalography electrodes. J Neurosurg, 141(4), 1115-1123. (Read full publication)
    6. Campbell JM, Yost S, Gautam D, Herich A, Botros D, Slaughter M, Chodakiewitz M, Arain A, Peters A, Richards S, Newman B, Johnson B, Rahimpour S, Shofty B (2024). Delays in the diagnosis and surgical treatment of drug-resistant epilepsy: A cohort study. Epilepsia, 65(5), 1314-1321. (Read full publication)
    7. Charlebois CM, Anderson DN, Smith EH, Davis TS, Newman BJ, Peters AY, Arain AM, Dorval AD, Rolston JD, Butson CR (2024). Circadian changes in aperiodic activity are correlated with seizure reduction in patients with mesial temporal lobe epilepsy treated with responsive neurostimulation. Epilepsia, 65(5), 1360-1373. (Read full publication)
    8. Anderson DN, Charlebois CM, Smith EH, Davis TS, Peters AY, Newman BJ, Arain AM, Wilcox KS, Butson CR, Rolston JD (2023). Closed-loop stimulation in periods with less epileptiform activity drives improved epilepsy outcomes. Brain, 147(2), 521-531. (Read full publication)
    9. Campbell JM, Kundu B, Lee JN, Miranda M, Arain A, Taussky P, Grandhi R, Rolston JD (2022). Evaluating the concordance of functional MRI-based language lateralization and Wada testing in epilepsy patients: A single-center analysis. Interv Neuroradiol, 29(5), 599-604. (Read full publication)
    10. Simon A, Nguyen D, Newman B, Arain A (2023). Uric Acid Nephropathy Secondary to Generalized Tonic-Clonic Seizures. Neurologist. (Read full publication)
    11. Kundu B, Arain A, Davis T, Charlebois CM, Rolston JD (2022). Using chronic recordings from a closed-loop neurostimulation system to capture seizures across multiple thalamic nuclei. Ann Clin Transl Neurol, 10(1), 136-143. (Read full publication)
    12. Charlebois CM, Anderson DN, Johnson KA, Philip BJ, Davis TS, Newman BJ, Peters AY, Arain AM, Dorval AD, Rolston JD, Butson CR (2022). Patient-specific structural connectivity informs outcomes of responsive neurostimulation for temporal lobe epilepsy. Epilepsia, 63(8), 2037-2055. (Read full publication)
    13. Miranda M, Arias F, Arain A, Newman B, Rolston J, Richards S, Peters A, Pick LH (2022). Neuropsychological evaluation in American Sign Language: A case study of a deaf patient with epilepsy. Epilepsy Behav Rep, 19, 100558. (Read full publication)
    14. Brown MG, Sillau S, McDermott D, Ernst LD, Spencer DC, Englot DJ, Gonzlez HFJ, Datta P, Karakis I, Becker D, Rolston JD, Arain A, Rao VR, Doherty M, Urban A, Drees C (2022). Concurrent brain-responsive and vagus nerve stimulation for treatment of drug-resistant focal epilepsy. Epilepsy Behav, 129, 108653. (Read full publication)
    15. Anderson DN, Charlebois CM, Smith EH, Arain AM, Davis TS, Rolston JD (2021). Probabilistic comparison of gray and white matter coverage between depth and surface intracranial electrodes in epilepsy. Sci Rep, 11(1), 24155. (Read full publication)
    16. Jehi L, Morita-Sherman M, Love TE, Bartolomei F, Bingaman W, Braun K, Busch RM, Duncan J, Hader WJ, Luan G, Rolston JD, Schuele S, Tassi L, Vadera S, Sheikh S, Najm I, Arain A, Bingaman J, Diehl B, de Tisi J, Rados M, Van Eijsden P, Wahby S, Wang X, Wiebe S (2021). Comparative Effectiveness of Stereotactic Electroencephalography Versus Subdural Grids in Epilepsy Surgery. Ann Neurol, 90(6), 927-939. (Read full publication)
    17. Frankel MA, Lehmkuhle MJ, Spitz MC, Newman BJ, Richards SV, Arain AM (2021). Wearable Reduced-Channel EEG System for Remote Seizure Monitoring. Front Neurol, 12, 728484. (Read full publication)
    18. Scoville JP, Joyce E, Hunsaker J, Reese J, Wilde H, Arain A, Bollo RL, Rolston JD (2020). Stereotactic Electroencephalography Is Associated With Reduced Pain and Opioid Use When Compared with Subdural Grids: A Case Series. Oper Neurosurg, 21(1), 6-13. (Read full publication)
    19. Kundu B, Davis TS, Philip B, Smith EH, Arain A, Peters A, Newman B, Butson CR, Rolston JD (2020). A systematic exploration of parameters affecting evoked intracranial potentials in patients with epilepsy. Brain Stimul, 13(5), 1232-1244. (Read full publication)
    20. Bornali Kundu, Tyler S Davis, Brian Philip, Elliot H Smith, Amir Arain, Angela Peters, Blake Newman, Christopher R Butson, John D Rolston (2020). A systematic exploration of parameters affecting evoked intracranial potentials in patients with epilepsy. Brain Stimul, 13(5), 1232-1244.
    21. Zaher N, Haas K, Sonmezturk H, Arain A, Abou-Khalil B (2019). Rhythmic ictal nonclonic hand (RINCH) motions in general EMU patients with focal epilepsy. Epilepsy Behav, 103(Pt A), 106666. (Read full publication)
    22. Naoir Zaher, Kevin Haas, Hasan Sonmezturk, Amir Arain, Bassel Abou-Khalil (2019). Rhythmic ictal nonclonic hand (RINCH) motions in general EMU patients with focal epilepsy. Epilepsy Behav, Feb. 2020, 103 pt. A.
    23. Arain AM, Umar A, Rawal P, Azar NJ, Obideen M, Singh P, Al-Kaylani M, Abou-Khalil B (2018). Localization value of ictal turning prone. Seizure, 69, 57-60. (Read full publication)
    24. Halford JJ, Westover MB, LaRoche SM, Macken MP, Kutluay E, Edwards JC, Bonilha L, Kalamangalam GP, Ding K, Hopp JL, Arain A, Dawson RA, Martz GU, Wolf BJ, Waters CG, Dean BC (2018). Interictal Epileptiform Discharge Detection in EEG in Different Practice Settings. J Clin Neurophysiol, 35(5), 375-380. (Read full publication)
    25. Baker MD, Abou-Khalil BW, Arain A, Tummala P, Azar NJ, Haas KF, Sonmezturk HH (2018). Lacosamide efficacy and tolerability in clinical practice - Post marketing analysis from a single dedicated epilepsy center. Clin Neurol Neurosurg, 171, 179-183. (Read full publication)
    26. Sagi V, Kim I, Bhatt AB, Sonmezturk H, Abou-Khalil BW, Arain AM (2017). Generalized paroxysmal fast activity in EEG: An unrecognized finding in genetic generalized epilepsy. Epilepsy Behav, 76, 101-104. (Read full publication)

    Review

    1. Ali S, Patel M, Jabeen S, Bailey RK, Patel T, Shahid M, Riley WJ, Arain A (2011). Insight into delirium. [Review]. Innov Clin Neurosci, 8(10), 25-34. (Read full publication)
    2. Ali S, Jabeen S, Arain A, Wassef T, Ibrahim A (2011). How to Use Your Clinical Judgment to Screen for and Diagnose Psychogenic Nonepileptic Seizures without Video Electroencephalogram. [Review]. Innov Clin Neurosci, 8(1), 36-42. (Read full publication)
    3. Arain AM, Abou-Khalil BW (2009). Management of new-onset epilepsy in the elderly. [Review]. Nat Rev Neurol, 5(7), 363-71. (Read full publication)
    4. Arain AM (2009). Pregabalin in the management of partial epilepsy. [Review]. Neuropsychiatr Dis Treat, 5, 407-13. (Read full publication)