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Anna M. Shestakova
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Anna M. Shestakova, MD, PhD

Languages spoken: Russian, Ukrainian, English

Dr. Shestakova is an assistant professor at University of Utah School of Medicine and a Medical Director of Hematopathology at ARUP Laboratories.

Specialties

  • Pathology, Clinical

Board Certification

American Board of Pathology (Sub: Hematopathology)
American Board of Pathology (Anatomic & Clinical)
Educational Commission for Foreign Medical Graduates
American Board of Pathology (Sub: Molecular Genetic Pathology)

Dr. Shestakova is an assistant professor at University of Utah School of Medicine and a Medical Director of Hematopathology at ARUP Laboratories.

Board Certification and Academic Information

Academic Departments Pathology -Assistant Professor (Clinical)
Board Certification
American Board of Pathology (Sub: Hematopathology)
American Board of Pathology (Anatomic & Clinical)
Educational Commission for Foreign Medical Graduates
American Board of Pathology (Sub: Molecular Genetic Pathology)

Education history

Professional Medical Medicine - Bogomolets National Medical University M.D.
Graduate Training Microbiology - Shupyk National Medical Academy of Postgraduate Education M.S.
Graduate Training Cell and Molecular Biology - University of Arkansas for Medical Sciences M.S.
Graduate Training Cell and Molecular Biology - University of Utah Ph.D.
Postdoctoral Fellowship Cell and Molecular Biology - University of Utah School of Medicine Postdoctoral Fellow
Residency Anatomical and Clinical Pathology - University of California, Irvine School of Medicine Resident
Fellowship Hematopathology - University of Michigan Fellow
Fellowship Molecular Genetic Pathology - University of Utah School of Medicine Fellow

Selected Publications

Journal Article

  1. Davies BA, Azmi IF, Payne J, Shestakova A, Horazdovsky BF, Babst M, Katzmann DJ (2010). Coordination of substrate binding and ATP hydrolysis in Vps4-mediated ESCRT-III disassembly. Mol Biol Cell, 21(19), 3396-408.
  2. Shestakova A, Hanono A, Drosner S, Curtiss M, Davies BA, Katzmann DJ, Babst M (2010). Assembly of the AAA ATPase Vps4 on ESCRT-III. Mol Biol Cell, 21(6), 1059-71.
  3. Sun Y, Shestakova A, Hunt L, Sehgal S, Lupashin V, Storrie B (2007). Rab6 regulates both ZW10/RINT-1 and conserved oligomeric Golgi complex-dependent Golgi trafficking and homeostasis. Mol Biol Cell, 18(10), 4129-42.
  4. Shestakova A, Curtiss M, Davies BA, Katzmann DJ, Babst M (2013). The linker region plays a regulatory role in assembly and activity of the Vps4 AAA ATPase. J Biol Chem, 288(37), 26810-9.
  5. Shestakova A, Suvorova E, Pavliv O, Khaidakova G, Lupashin V (2007). Interaction of the conserved oligomeric Golgi complex with t-SNARE Syntaxin5a/Sed5 enhances intra-Golgi SNARE complex stability. J Cell Biol, 179(6), 1179-92.
  6. Tashi T, Scott Reading N, Wuren T, Zhang X, Moore LG, Hu H, Tang F, Shestakova A, Lorenzo F, Burjanivova T, Koul P, Guchhait P, Wittwer CT, Julian CG, Shah B, Huff CD, Gordeuk VR, Prchal JT, Ge R (2017). Gain-of-function EGLN1 prolyl hydroxylase (PHD2 D4E:C127S) in combination with EPAS1 (HIF-2¿) polymorphism lowers hemoglobin concentration in Tibetan highlanders. J Mol Med (Berl), 95(6), 665-670.
  7. Shestakova A, Zolov S, Lupashin V (2006). COG complex-mediated recycling of Golgi glycosyltransferases is essential for normal protein glycosylation. Traffic, 7(2), 191-204.
  8. Shestakova A, Nael A, Nora V, Rezk S, Zhao (2021). Automated leukocyte parameters are useful in the assessment of myelodysplastic syndromes. Cytometry. Part B, Clinical cytometry, 100(3), 299-311.
  9. Lanikova L, Reading NS, Hu H, Tashi T, Burjanivova T, Shestakova A, Siwakoti B, Thakur BK, Pun CB, Sapkota A, Abdelaziz S, Feng BJ, Huff CD, Hashibe M, Prchal J (2017). Evolutionary selected Tibetan variants of HIF pathway and risk of lung cancer. Oncotarget, 8(7), 11739-11747.
  10. Shestakova A, Tarabay J, Burtsev A, Ibe I, Kim J, Chandan V, Armstrong WB, Tjoson T, Wang (2021). Increased PD-L1 and p16 expression are common in oropharyngeal squamous cell carcinoma. Future science OA, 7(9), FSO768.
  11. Shestakova A, Haghighi N, Zhang Y, Tarabay J, Evans MG, Burtsev A, Chan JY, Gamayo A, Zhao X, O'Brien S, Quintero-Rivera F, Rezk S (2025). Mutational landscape of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) involving the central nervous system. Leukemia & lymphoma, 66(6), 1132-1137.
  12. Shestakova A, Shao L, Smith LB, Ryan R, Bedell V, Murata-Collins J, Zhang W, Perry AM, Song J (2023). High-grade B-cell lymphoma with concurrent MYC rearrangement and 11q aberrations: clinicopathologic, cytogenetic, and molecular characterization of 4 cases. Human pathology, 136, 34-43.
  13. Shestakova A, Rets AV, Menon (2025). Autoimmune Hepatobiliary Disease and Cryoglobulins in Peripheral Blood. American journal of hematology, 100(12), 2373-2374.
  14. Ok CY, Natu A, Daneshpajouhnejad P, Fathalla LA, Symes E, Barone P, Shestakova A, Foucar KK, Bueso-Ramos C, Montalban-Bravo G, Orazi A, Patnaik M, Hasserjian R, Arber D, Geyer JT, Bagg A, Reichard KK, Wang S (2025). Chronic myelomonocytic leukemia in the young (aged 50 years and younger): Divergent clinical and molecular characteristics from the elderly. Cancer, 131(22), e70176.

Review

  1. Shestakova G, Edgar NU, Rets A (2025). Common Hematologic Emergencies-Acute Promyelocytic Leukemia and Microangiopathic Hemolytic Anemias-A Pivotal Role of Clinical Laboratory. International journal of laboratory hematology,

Case Report

  1. Shestakova A, Grove N, Said J, Song S, Quintero-Rivera (2020). Trisomy 3, a sole recurrent cytogenetic abnormality in pediatric polymorphic post-transplant lymphoproliferative disorder (PTLD). Cancer genetics, 248-249, 39-48.
  2. Shestakova A, Rezk S, Ghasemizadeh D, Nael A, Zhao (2020). High-grade B-cell Lymphoma with MYC and BCL2 Rearrangement Arising from Follicular Lymphoma: Presentation as a Large Peripancreatic Mass. Diagnostics (Basel, Switzerland), 10(3),

Letter

  1. Evans MG, Shestakova A, Haghighi N, Zhao X, Nardi V, Pinter-Brown LC, Rezk S (2022). Rare case of leptomeningeal small lymphocytic lymphoma with TP53 mutation detected by deep next-generation sequencing. Leukemia & lymphoma, 63(10), 2479-2483.