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Anna M. Shestakova

Anna M. Shestakova, MD, PhD

Languages spoken: English, Russian, Ukrainian
  • Specialties

    • Pathology, Clinical
  • Board Certification and Academic Information

    Academic Departments Pathology -Primary

    Education history

    Fellowship Molecular Genetic Pathology - University of Utah School of Medicine Fellow
    Hematopathology - University of Michigan Fellow
    Residency Anatomical and Clinical Pathology - University of California, Irvine School of Medicine Resident
    Cell and Molecular Biology - University of Utah School of Medicine Postdoctoral Fellow
    Graduate Training Cell and Molecular Biology - University of Utah Ph.D.
    Cell and Molecular Biology - University of Arkansas for Medical Sciences M.S.
    Graduate Training Microbiology - Shupyk National Medical Academy of Postgraduate Education M.S.
    Medicine - Bogomolets National Medical University M.D.

    Selected Publications

    Journal Article

    1. Shestakova A, Tarabay J, Burtsev A, Ibe I, Kim J, Chandan V, Armstrong WB, Tjoson T, Wang B (2021). Increased PD-L1 and p16 expression are common in oropharyngeal squamous cell carcinoma. Future Sci OA, 7(9), FSO768.
    2. Shestakova A, Nael A, Nora V, Rezk S, Zhao X (2020). Automated leukocyte parameters are useful in the assessment of myelodysplastic syndromes. Cytometry B Clin Cytom, 100(3), 299-311.
    3. Tashi T, Scott Reading N, Wuren T, Zhang X, Moore LG, Hu H, Tang F, Shestakova A, Lorenzo F, Burjanivova T, Koul P, Guchhait P, Wittwer CT, Julian CG, Shah B, Huff CD, Gordeuk VR, Prchal JT, Ge R (2017). Gain-of-function EGLN1 prolyl hydroxylase (PHD2 D4E:C127S) in combination with EPAS1 (HIF-2α) polymorphism lowers hemoglobin concentration in Tibetan highlanders. J Mol Med (Berl), 95(6), 665-670.
    4. Lanikova L, Reading NS, Hu H, Tashi T, Burjanivova T, Shestakova A, Siwakoti B, Thakur BK, Pun CB, Sapkota A, Abdelaziz S, Feng BJ, Huff CD, Hashibe M, Prchal JT (2016). Evolutionary selected Tibetan variants of HIF pathway and risk of lung cancer. Oncotarget, 8(7), 11739-11747.
    5. Shestakova A, Curtiss M, Davies BA, Katzmann DJ, Babst M (2013). The linker region plays a regulatory role in assembly and activity of the Vps4 AAA ATPase. J Biol Chem, 288(37), 26810-9.
    6. Davies BA, Azmi IF, Payne J, Shestakova A, Horazdovsky BF, Babst M, Katzmann DJ (2010). Coordination of substrate binding and ATP hydrolysis in Vps4-mediated ESCRT-III disassembly. Mol Biol Cell, 21(19), 3396-408.
    7. Shestakova A, Hanono A, Drosner S, Curtiss M, Davies BA, Katzmann DJ, Babst M (2010). Assembly of the AAA ATPase Vps4 on ESCRT-III. Mol Biol Cell, 21(6), 1059-71.
    8. Shestakova A, Suvorova E, Pavliv O, Khaidakova G, Lupashin V (2007). Interaction of the conserved oligomeric Golgi complex with t-SNARE Syntaxin5a/Sed5 enhances intra-Golgi SNARE complex stability. J Cell Biol, 179(6), 1179-92.
    9. Sun Y, Shestakova A, Hunt L, Sehgal S, Lupashin V, Storrie B (2007). Rab6 regulates both ZW10/RINT-1 and conserved oligomeric Golgi complex-dependent Golgi trafficking and homeostasis. Mol Biol Cell, 18(10), 4129-42.
    10. Shestakova A, Zolov S, Lupashin V (2006). COG complex-mediated recycling of Golgi glycosyltransferases is essential for normal protein glycosylation. Traffic, 7(2), 191-204.

    Case Report

    1. Shestakova A, Grove N, Said J, Song S, Quintero-Rivera F (2020). Trisomy 3, a sole recurrent cytogenetic abnormality in pediatric polymorphic post-transplant lymphoproliferative disorder (PTLD). Cancer Genet, 248-249, 39-48.
    2. Shestakova A, Rezk S, Ghasemizadeh D, Nael A, Zhao X (2020). High-grade B-cell Lymphoma with MYC and BCL2 Rearrangement Arising from Follicular Lymphoma: Presentation as a Large Peripancreatic Mass. Diagnostics (Basel), 10(3).