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Guillaume Lamotte
( out of 258 reviews )

Guillaume Lamotte, MD, MSc

Languages spoken: French, English

Clinical Locations

Primary Location

Imaging & Neurosciences Center

729 Arapeen Dr
Salt Lake City , UT 84108

Dr. Lamotte has a broad background in medicine and neurology with specialty training and expertise in movement disorders and autonomic disorders. He completed a neurology residency at the University Hospital of Caen in France and did a year of supplementary training in movement disorders during his first neurology residency. He then completed the clinician-scientist track between the National Institutes of Health (NIH) and Medstar Georgetown University Hospital as his second neurology residency in the United States. He worked under the guidance of Dr. David Goldstein in the autonomic medicine section at the NIH and developed his clinical skills in autonomic medicine through history taking and physical examinations, as well as exposure to autonomic function testing procedures. He gained experience in conducting clinical research in autonomic disorders focusing on autonomic nervous system dysfunction in synucleinopathies. He completed a clinical fellowship at the Mayo Clinic in Rochester, MN, where he had a broad exposure to various autonomic disorders in the clinic and autonomic laboratory. He is pursuing an academic career focused on clinical research in the fields of autonomic and movement disorders and is currently an associate professor in neurology at the University of Utah, Salt Lake City, UT, where he sees patients with movement disorders and autonomic disorders.

Board Certification

National Board of Medical Examiners
American Board of Psychiatry & Neurology (Neurology)
United Council for Neurologic Subspecialties (Autonomic Disorders)
Educational Commission for Foreign Medical Graduates

Patient Rating

4.9 /5
( out of 258 reviews )

The patient rating score is an average of all responses on our patient experience survey. The rating averages scores for all questions about care from our providers.

The scale on which responses are measured is 1 to 5 with 5 being the best score.

Patient Comments

Patient comments are gathered from our patient experience survey and displayed in their entirety. For the convenience of our visitors, some patient comments have been translated from their original language into English while preserving their original meaning as accurately as possible. Patients are de-identified for confidentiality and patient privacy.

CLINICAL NEUROSCIENCES CENTER

Helped me understand. after two years of seeing other Doctors, he helped me understand. Thanks

CLINICAL NEUROSCIENCES CENTER

Again, I really appreciate that Dr. Lamotte is not afraid to share his opinion on various questions.

CLINICAL NEUROSCIENCES CENTER

Very good

CLINICAL NEUROSCIENCES CENTER

Great guy, very responsive to your needs. Shows compassion.

CLINICAL NEUROSCIENCES CENTER

De. Lamotte is very thorough, and is an excellent listener.

CLINICAL NEUROSCIENCES CENTER

Very knowledgeable and responsive

CLINICAL NEUROSCIENCES CENTER

I am so grateful for Dr Lamotte. He has been so helpful in my care. He's always direct and clear and I trust his knowledge and expertise. He has been a valuable and key member of my health care team.

CLINICAL NEUROSCIENCES CENTER

Excellent man Doctor. [TRANSLATED]

CLINICAL NEUROSCIENCES CENTER

I have had essential tremor for 30 years. I am very happy that I found Dr. Lamotte to help me. He is starting low and slow. Dr. Lamotte has given me the faith that there will be options to help me. We talked about fishing, too!

Dr. Lamotte has a broad background in medicine and neurology with specialty training and expertise in movement disorders and autonomic disorders. He completed a neurology residency at the University Hospital of Caen in France and did a year of supplementary training in movement disorders during his first neurology residency. He then completed the clinician-scientist track between the National Institutes of Health (NIH) and Medstar Georgetown University Hospital as his second neurology residency in the United States. He worked under the guidance of Dr. David Goldstein in the autonomic medicine section at the NIH and developed his clinical skills in autonomic medicine through history taking and physical examinations, as well as exposure to autonomic function testing procedures. He gained experience in conducting clinical research in autonomic disorders focusing on autonomic nervous system dysfunction in synucleinopathies. He completed a clinical fellowship at the Mayo Clinic in Rochester, MN, where he had a broad exposure to various autonomic disorders in the clinic and autonomic laboratory. He is pursuing an academic career focused on clinical research in the fields of autonomic and movement disorders and is currently an associate professor in neurology at the University of Utah, Salt Lake City, UT, where he sees patients with movement disorders and autonomic disorders.

Board Certification and Academic Information

Academic Departments Neurology -Associate Professor (Clinical)
Board Certification
National Board of Medical Examiners
American Board of Psychiatry & Neurology (Neurology)
United Council for Neurologic Subspecialties (Autonomic Disorders)
Educational Commission for Foreign Medical Graduates

Education history

Graduate Training Anatomy - University of Caen Basse-Normandie M.S.
Graduate Training Infectious Disease and Tropical Disease - University of Caen Basse-Normandie M.S.
Professional Medical Medicine - University of Caen Basse-Normandie M.D.
Residency Neurology - University Hospital of Caen Basse Normandie Resident
Diploma Movement Disorders - Groupe Hospitalier Pitié Salpêtrière, Paris, France Diploma
Graduate Training Neurosciences - University of Caen M.S.
Residency Internal Medicine - National Institutes of Health / MedStar Georgetown University Hospital Resident
Residency Neurology (Clinician Scientist Track) - National Institutes of Health / MedStar Georgetown University Hospital Resident
Residency Neurology - National Institutes of Health / MedStar Georgetown University Hospital Academic Chief Resident
Fellowship Autonomic Disorders - Mayo Clinic Fellow

Selected Publications

Journal Article

  1. Lamotte G, Holmes C, Sullivan P, Goldstein DS (2019). Substantial renal conversion of L-threo-3,4-dihydroxyphenylserine (droxidopa) to norepinephrine in patients with neurogenic orthostatic hypotension. Clin Auton Res, 29(1), 113-117.
  2. Lamotte G, Takahashi M, Wu T, Sullivan P, Cherup J, Holmes C, Goldstein DS (2021). Do indices of baroreflex failure and peripheral noradrenergic deficiency predict the magnitude of orthostatic hypotension in Lewy body diseases? Clin Auton Res, 31(4), 543-551.
  3. Shouman K, Vanichkachorn G, Cheshire WP, Suarez MD, Shelly S, Lamotte GJ, Sandroni P, Benarroch EE, Berini SE, Cutsforth-Gregory JK, Coon EA, Mauermann ML, Low PA, Singer W (2021). Autonomic dysfunction following COVID-19 infection: an early experience. Clin Auton Res, 31(3), 385-394.
  4. Goldstein DS, Isonaka R, Lamotte G, Kaufmann (2021). Different phenoconversion pathways in pure autonomic failure with versus without Lewy bodies. Clinical autonomic research, 31(6), 677-684.
  5. Lamotte G, Sandroni (2021). A practical approach to peripheral autonomic neuropathies. Current opinion in neurology, 34(5), 638-647.
  6. Lenka A, Mittal SO, Lamotte G, Pagan F (2021). A Pragmatic Approach to the Perioperative Management of Parkinson's Disease. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 48(3), 299-307.
  7. Lamotte G, Morello R, Lebasnier A, Agostini D, Bouvard G, De La Sayette V, Defer G (2016). Influence of education on cognitive performance and dopamine transporter binding in dementia with Lewy bodies. Clinical neurology and neurosurgery, 146, 138-43.
  8. Lamotte G, Coon EA, Suarez MD, Sandroni P, Benarroch E, Cutsforth-Gregory JK, Mauermann ML, Berini SE, Shouman K, Sletten D, Goodman BP, Low PA, Singer (2022). Standardized Autonomic Testing in Patients With Probable Radiation-Induced Afferent Baroreflex Failure. Hypertension (Dallas, Tex., 79(1), 50-56.
  9. Goldstein DS, Sullivan P, Holmes C, Lamotte G, Lenka A, Sharabi (2021). Differential abnormalities of cerebrospinal fluid dopaminergic versus noradrenergic indices in synucleinopathies. Journal of neurochemistry, 158(2), 554-568.
  10. Lamotte G, Sandroni P, Cutsforth-Gregory JK, Berini SE, Benarroch EE, Shouman K, Mauermann ML, Anderson J, Low PA, Singer W, Coon E (2021). Clinical presentation and autonomic profile in Ross syndrome. Journal of neurology, 268(10), 3852-3860.
  11. Lamotte G, Lenka (2021). Brainstem Predominant Posterior Reversible Encephalopathy Syndrome. Neurology India, 69(2), 536-537.
  12. Lamotte (2018). Author response: Mystery Case: A case of fulminant encephalopathy in a 69-year-old woman. Neurology, 90(15), 714.
  13. Lamotte G, Farzal Z, Zimmerman WD, Han S, de Brito P, Mayson (2017). Clinical Reasoning: Monocular vision loss, ophthalmoplegia, and strokes in a 61-year-old man with diabetes mellitus. Neurology, 89(24), e276-e281.
  14. Lamotte G, Williams (2017). Mystery Case: A case of fulminant encephalopathy in a 69-year-old woman. Neurology, 89(9), e109-e114.
  15. Lamotte G, Coon EA, Suarez MD, Sandroni P, Benarroch EE, Cutsforth-Gregory JK, Mauermann ML, Berini SE, Shouman K, Sletten D, Goodman BP, Low PA, Singer (2021). Natural History of Afferent Baroreflex Failure in Adults. Neurology, 97(2), e136-e144.
  16. Lamotte G, Benarroch E (2021). What Is the Clinical Correlation of Cardiac Noradrenergic Denervation in Parkinson Disease?. Neurology, 96(16), 748-753.
  17. Lamotte G, Agostini (2017). Erratum to: Cardiac 123I-MIBG scintigraphy: A window into the brain in Parkinsonism?. Journal of nuclear cardiology, 24(1), 111.
  18. Lamotte G, Holmes C, Wu T, Goldstein D (2019). Long-term trends in myocardial sympathetic innervation and function in synucleinopathies. Parkinsonism & related disorders, 67, 27-33.
  19. Lamotte (2021). Central pontine myelinolysis secondary to rapid correction of hyponatremia historical perspective with Doctor Robert Laureno. Neurological sciences, 42(8), 3479-3483.
  20. Lamotte G, Shah RC, Lazarov O, Corcos D (2017). Exercise Training for Persons with Alzheimer's Disease and Caregivers: A Review of Dyadic Exercise Interventions. Journal of motor behavior, 49(4), 365-377.
  21. Lamotte G, Shouman K, Benarroch E (2021). Stress and central autonomic network. Autonomic neuroscience, 235, 102870.
  22. Lamotte G, Morello R, Lebasnier A, Agostini D, Defer G (2015). Accuracy and cutoff values of delayed heart to mediastinum ratio with (123)I-metaiodobenzylguanidine cardiac scintigraphy for Lewy body disease diagnoses. BMC neurology, 15, 83.
  23. Lebasnier A, Lamotte G, Manrique A, Peyronnet D, Bouvard G, Defer G, Agostini (2015). Potential diagnostic value of regional myocardial adrenergic imaging using (123)I-MIBG SPECT to identify patients with Lewy body diseases. European journal of nuclear medicine and molecular imaging, 42(7), 1043-51.
  24. Laureno R, Lamotte G, Mark A (2018). Sequential MRI in pontine and extrapontine myelinolysis following rapid correction of hyponatremia. BMC research notes, 11(1), 707.
  25. Lamotte G, Rafferty MR, Prodoehl J, Kohrt WM, Comella CL, Simuni T, Corcos D (2015). Effects of endurance exercise training on the motor and non-motor features of Parkinson's disease: a review. Journal of Parkinson's disease, 5(1), 21-41.
  26. Castillo-Pinto C, Lamotte G, et a (2020). Healthcare Worker With Large Vessel Acute Ischemic Stroke Likely Related to Mild SARS-CoV-2 Infection. The Neurohospitalist,
  27. Lamotte G, Holmes C, Sullivan P, Lenka A, Goldstein D (2020). Cardioselective peripheral noradrenergic deficiency in Lewy body synucleinopathies. Annals of clinical and translational neurology, 7(12), 2450-2460.
  28. Lenka A, Lamotte G, Goldstein D (2021). Cardiac 18F-Dopamine PET Distinguishes PD with Orthostatic Hypotension from Parkinsonian MSA. Movement disorders clinical practice, 8(4), 582-586.
  29. Lamotte G, Skender E, Rafferty MR, David F, Sadowsky S, Corcos D (2015). Effects of progressive resistance exercise training on the motor and non-motor features of Parkinson’s disease: a review. 4, 11-27.
  30. Castillo-Pinto C, Lamotte G, Mehta A, Sonti R, Di Maria G, Ruiz D, Kumar PN, Stemer AB, Denny M (2022). Healthcare Worker With Large Vessel Acute Ischemic Stroke Likely Related to Mild SARS-CoV-2 Infection. The Neurohospitalist, 12(1), 48-56.
  31. Laureno R, Lamotte (2021). The midline cerebellar lesion in experimental Wernicke disease. Neurology India, 69(6), 1624.
  32. Griffith G, Lamotte G, Mehta N, Fan P, Nikolich J, Springman V, Suttman E, Joslin E, Balfany K, Dunlap M, Kohrt WM, Christiansen CL, Melanson EL, Josbeno D, Chahine LM, Patterson CG, Corcos D (2024). Chronotropic Incompetence During Exercise Testing as a Marker of Autonomic Dysfunction in Individuals with Early Parkinson's Disease. Journal of Parkinson's disease,
  33. Corcos DM, Lamotte G, Luthra NS, McKee K (2023). Advice to People with Parkinson's in My Clinic: Exercise. Journal of Parkinson's disease,
  34. Lenka A, Lamotte G, Beach (2023). Asymptomatic orthostatic hypotension in synucleinopathies: to treat or not to treat?. Clinical autonomic research,
  35. Lamotte G, Sandroni (2022). Updates on the Diagnosis and Treatment of Peripheral Autonomic Neuropathies. Current neurology and neuroscience reports, 22(12), 823-837.
  36. Patterson CG, Joslin E, Gil AB, Spigle W, Nemet T, Chahine L, Christiansen CL, Melanson E, Kohrt WM, Mancini M, Josbeno D, Balfany K, Griffith G, Dunlap MK, Lamotte G, Suttman E, Larson D, Branson C, McKee KE, Goelz L, Poon C, Tilley B, Kang UJ, Tansey MG, Luthra N, Tanner CM, Haus JM, Fantuzzi G, McFarland NR, Gonzalez-Latapi P, Foroud T, Motl R, Schwarzschild MA, Simuni T, Marek K, Naito A, Lungu C, Corcos DM, SPARX3-PSG Investigator (2022). Study in Parkinson's disease of exercise phase 3 (SPARX3): study protocol for a randomized controlled trial. Trials, 23(1), 855.
  37. Lamotte G, Lenka (2022). Orthostatic Hypotension in Parkinson Disease: What Is New?. Neurology. Clinical practice, 12(5), e112-e115.
  38. Lenka A, Di Maria G, Lamotte G, Bahroo L, Jankovic (2022). Practical pearls to improve the efficacy and tolerability of levodopa in Parkinson's disease. Expert review of neurotherapeutics, 22(6), 489-498.
  39. Earl T, Jridi A, Thulin PC, Zorn M, McKee KE, Mitrovich K, Moretti P, Alshaikh J, Kassavetis P, Cortez MM, Lamotte (2024). Effect of levodopa on postural blood pressure changes in Parkinson disease: a randomized crossover study. Clinical autonomic research, 34(1), 117-124.
  40. Rasmussen TK, Borghammer P, Finnerup NB, Jensen TS, Hansen J, Knudsen K, Singer W, Lamotte G, Terkelsen A (2024). Functional and (123)I-MIBG scintigraphy assessment of cardiac adrenergic dysfunction in diabetes. Autonomic neuroscience, 252, 103155.
  41. Gibbons CH, Levine T, Adler C, Bellaire B, Wang N, Stohl J, Agarwal P, Aldridge GM, Barboi A, Evidente VGH, Galasko D, Geschwind MD, Gonzalez-Duarte A, Gil R, Gudesblatt M, Isaacson SH, Kaufmann H, Khemani P, Kumar R, Lamotte G, Liu AJ, McFarland NR, Miglis M, Reynolds A, Sahagian GA, Saint-Hillaire MH, Schwartzbard JB, Singer W, Soileau MJ, Vernino S, Yerstein O, Freeman (2024). Skin Biopsy Detection of Phosphorylated ¿-Synuclein in Patients With Synucleinopathies. JAMA,
  42. Griffith GJ, Mehta N, Lamotte G, McKee KE, Suttman E, Haus JM, Joslin E, Balfany K, Kohrt WM, Christiansen CL, Melanson EL, Chahine LM, Christou DD, Patterson CG, Corcos D (2025). Effects of 6 months of endurance exercise on motor function, exercise capacity, and autonomic function based on presence of autonomic dysfunction in individuals with early Parkinson's disease. Journal of Parkinson's disease, 1877718X241308813.
  43. Ziaks L, Johnson K, Schiltz K, Pelo R, Lamotte G, Dal Molin C, Chung T, Cortez M (2024). Adaptive Approaches to Exercise Rehabilitation for Postural Tachycardia Syndrome and Related Autonomic Disorders. Archives of rehabilitation research and clinical translation, 6(4), 100366.
  44. Lamotte G, McKee KE, Luthra NS, Corcos D (2024). Advice to People with Parkinson's in My Clinic: Orthostatic Hypotension. Journal of Parkinson's disease, 14(6), 1139-1146.
  45. Griffith GJ, McKee KE, Lamotte G, Luthra NS, Corcos D (2025). Advice to people with Parkinson's in my clinic: Get a cardiopulmonary exercise test. Journal of Parkinson's disease, 15(3), 654-663.

Review

  1. Lamotte G, Singer (2023). Synucleinopathies. Handbook of clinical neurology, 196, 175-202.
  2. Bruno MK, Dhall R, Duquette A, Haq IU, Honig LS, Lamotte G, Mari Z, McFarland NR, Montaser-Kouhsari L, Rodriguez-Porcel F, Shurer J, Siddiqui J, Spears CC, Wills AA, Diaz K, Golbe LI, as the Diagnosis and Treatment Working Group, CurePSP Center of Care (CoC) Networ (2024). A General Neurologist's Practical Diagnostic Algorithm for Atypical Parkinsonian Disorders: A Consensus Statement. Neurology. Clinical practice, 14(6), e200345.
  3. Luthra NS, Mehta N, Munoz MJ, Fantuzzi G, Lamotte G, Haus JM, McFarland NR, Tansey MG, Gonzalez-Latapi P, Caraveo G, Kang UJ, Corcos D (2025). Aerobic exercise-induced changes in fluid biomarkers in Parkinson's disease. NPJ Parkinson's disease, 11(1), 190.

Book Chapter

  1. Guillaume Lamotte, Norman L. Foste (2023). Appropriate Use of Biomarkers in Suspected Neurodegenerative Diseases.

Editorial

  1. Lamotte G, Boes CJ, Low PA, Coon EA (2021). The expanding role of the cold pressor test: a brief history. Clin Auton Res, 31(2), 153-155.
  2. Lamotte G, Millar Vernetti (2021). Inhibition of the norepinephrine transporter to treat neurogenic orthostatic hypotension: is this the end of the story?. Clinical autonomic research, 31(6), 645-647.
  3. Lamotte G, Becker (2020). Toward biomarker-based clinical subtyping of Parkinson disease. Neurology, 95(11), 461-462.
  4. Guillaume L, Denis (2017). Cardiac 123I-MIBG scintigraphy: A window into the brain in Parkinsonism?. Journal of nuclear cardiology, 24(1), 108-110.
  5. Lamotte G, Goldstein D (2022). What new can we learn from cardiac sympathetic neuroimaging in synucleinopathies?. Clinical autonomic research,
  6. Lamotte (2023). Recent updates in autonomic research: new insights into vagal nerve activity during exercise, cardiac autonomic neuropathy and silent myocardial infarction in diabetes, and timing of orthostatic blood pressure change and future risk of dementia. Clinical autonomic research, 33(6), 619-621.
  7. Baker JR, Bourne KM, Lamotte (2023). Recent updates in autonomic research: a focus on new technologies with high-resolution procedures to study sympathetic nerve activity, plasma proteomic profiling in POTS, and non-invasive neuromodulation with focused ultrasound. Clinical autonomic research, 33(1), 11-14.
  8. Lamotte G, Kaufmann H, Jordan (2023). The Clinical Autonomic Research journal 2022 and onward. Clinical autonomic research, 33(1), 1-2.
  9. Lamotte G, Cheshire W (2022). Do not forget about caregivers in autonomic medicine!. Clinical autonomic research, 32(6), 403-404.
  10. Lamotte G, Kaufmann (2022). Movement disorder society criteria for the diagnosis of multiple system atrophy-what's new?. Clinical autonomic research, 32(3), 163-165.

Letter

  1. Lamotte G, Benarroch EE, Coon EA (2021). Paroxysmal hypothermia and hyperhidrosis with exacerbation after COVID-19 Infection. [Letter to the editor]. Clin Auton Res, 31(2), 327-329.
  2. Lamotte G, Sandroni P (2021). A case of Ross syndrome associated with systemic sclerosis. [Letter to the editor]. Clin Auton Res, 31(3), 463-465.
  3. Cutsforth-Gregory JK, Benarroch EE, Lamotte G (2021). Platypnea-orthodeoxia syndrome mimicking postural orthostatic tachycardia syndrome. [Letter to the editor]. Clin Auton Res, 31(4), 573-576.
  4. Chochol MD, Kataria L, O'Rourke MC, Lamotte (2019). Clozapine-Associated Myoclonus and Stuttering Secondary to Smoking Cessation and Drug Interaction: A Case Report. Journal of clinical psychopharmacology, 39(3), 275-277.
  5. Lamotte G, Laballe R, Dupuy (2014). Bilateral eyelid retraction, loss of vision, ophthalmoplegia: an atypical triad in anti-GQ1b syndrome. Revue neurologique, 170(6-7), 469-70.
  6. Lamotte G, Caillot A, Di Palma C, Lechapt-Zalcman E, Benateau H, Cogez (2014). Intramedullary metastasis of a cutaneous squamous cell carcinoma. Revue neurologique, 170(3), 230-2.
  7. Lamotte G, Danaila TC, Jaillon-Rivière V, Hitier M, Defer G (2014). Paraneoplastic opsoclonus myoclonus with autoantibodies to glutamic acid decarboxylase. Revue neurologique, 170(1), 50-1.
  8. Lamotte G, Cogez J, Viader (2012). Interferon-ß-1a-induced psychosis in a patient with multiple sclerosis. Psychiatry and clinical neurosciences, 66(5), 462.
  9. Zahid A, Coon EA, Lamotte (2021). "No man is an island"-unique pattern of anhidrosis with islands of preserved sweat in Ross syndrome. Neurological sciences, 42(12), 5399-5400.
  10. Goldstein DS, Holmes C, Sullivan P, Isonaka R, Maric D, Alam P, Cliatt-Brown C, Gelsomino J, Moore S, Caughey B, Lamotte (2025). "Body-first" dementia with Lewy bodies. Clinical autonomic research,

Other

  1. Lamotte G, Rafferty MR, Prodoehl J, Kohrt WM, Comella CL, Simuni T, Corcos D (2015). Effects of Endurance Exercise Training on The Motor and Non-Motor Features of Parkinson's Disease: A Review. Journal of Parkinson's disease, 5(4), 993.