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Jessica A. Meznarich
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Jessica A. Meznarich, MD

Languages spoken: English, Mandarin Chinese

Clinical Locations

Primary Children's Hospital

Salt Lake City
801-662-2900
  • Dr. Meznarich received her medical degree from the University of Washington School of Medicine in Seattle, Washington. She then completed her residency in Pediatrics and fellowship in Pediatric Hematology and Oncology at the University of Utah/Primary Children’s Hospital in Salt Lake City, Utah.

    She joined the faculty of the University of Utah in 2016, where she is currently an Associate Professor of Pediatrics in the Division of Pediatric Hematology and Oncology. Her clinical and research interests are in non-malignant hematology, bleeding disorders, thrombosis and clotting disorders, and hemoglobinopathies including thalassemia and sickle cell disease.

    Board Certification

    American Board of Pediatrics (Pediatrics)
    American Board of Pediatrics (Sub: Pediatric Hematology-Oncology)
  • Dr. Meznarich received her medical degree from the University of Washington School of Medicine in Seattle, Washington. She then completed her residency in Pediatrics and fellowship in Pediatric Hematology and Oncology at the University of Utah/Primary Children’s Hospital in Salt Lake City, Utah.

    She joined the faculty of the University of Utah in 2016, where she is currently an Associate Professor of Pediatrics in the Division of Pediatric Hematology and Oncology. Her clinical and research interests are in non-malignant hematology, bleeding disorders, thrombosis and clotting disorders, and hemoglobinopathies including thalassemia and sickle cell disease.

    Board Certification and Academic Information

    Academic Departments Pediatrics -Primary
    Academic Divisions Hematology/Oncology
    Board Certification
    American Board of Pediatrics (Pediatrics)
    American Board of Pediatrics (Sub: Pediatric Hematology-Oncology)

    Education history

    Fellowship Pediatric Hematology-Oncology - University of Utah School of Medicine Fellow
    Pediatrics - University of Utah School of Medicine Resident
    Professional Medical Medicine - University of Washington School of Medicine M.D.
    Biochemistry, Chemistry - University of Washington B.S.

    Selected Publications

    Journal Article

    1. Patel PK, Chinga ML, Yilmaz M, Joychan S, Ujhazi B, Ellison M, Gordon S, Nieves D, Csomos K, Eslin D, Afify ZA, Meznarich J, Bohnsack J, Walkovich K, Seidel MG, Sharapova S, Boyarchyk O, Latysheva E, Tuzankina I, Shaker AB, Ayala I, Sriaroon P, Westermann-Clark E, Walter JE (2024). Clinical and Treatment History of Patients with Partial DiGeorge Syndrome and Autoimmune Cytopenia at Multiple Centers. J Clin Immunol, 44(2), 42. (Read full article)
    2. Fan EM, Vagher J, Meznarich JA, Ubico EM, Goteti S, Peterson D, Rayes A, Maese LD (2023). Severe congenital neutropenia, SRP54 pathogenicity, and a framework for surveillance. Am J Med Genet A, 191(5), 1434-1441.
    3. Bahr TM, Agarwal AM, Meznarich JA, Prince WL, Wait TWP, Prchal JT, Christensen RD (2021). Thirty-five males with severe (Class 1) G6PD deficiency (c.637G>T) in a North American family of European ancestry. Blood Cells Mol Dis, 92, 102625. (Read full article)
    4. Niss O, Lorsbach RB, Berger M, Chonat S, McLemore M, Buchbinder D, McCavit T, Shaffer LG, Simpson J, Schwartz JH, Meznarich J, Emberesh M, Seu KG, Zhang W, Kalfa TA, CDAR consortium (2020). Congenital dyserythropoietic anemia type I: First report from the Congenital Dyserythropoietic Anemia Registry of North America (CDAR). Blood Cells Mol Dis, 87, 102534. (Read full article)
    5. Bahr, TM, Knudsen, MC, Lozano-Chinga, M, Agarwal, AM, Meznarich, JA, Ohls, RK, Christensen, RD (2020). Infantile Pyknocytosis: End-Tidal CO, %Micro-R Measurements, Next-Generation Sequencing, and Transfusion Avoidance with Darbepoetin . 5.
    6. Seu KG, Trump LR, Emberesh S, Lorsbach RB, Johnson C, Meznarich J, Underhill HR, Chou ST, Sakthivel H, Nassar NN, Seu KJ, Blanc L, Zhang W, Lutzko CM, Kalfa TA (2020). VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects. Am J Hum Genet, 107(6), 1149-1156. (Read full article)
    7. Bahr TM, Lozano-Chinga M, Agarwal AM, Meznarich JA, Gerday E, Smoot JL, Taylor A, Christensen RD (2020). Dizygotic twins with prolonged jaundice and microcytic, hypochromic, hemolytic anemia with pyropoikilocytosis. Blood Cells Mol Dis, 85, 102462. (Read full article)
    8. Meznarich JA, Draper L, Christensen RD, Yaish HM, Luem ND, Pysher TJ, Jung G, Nemeth E, Ganz T, Ward DM (2018). Fetal presentation of congenital dyserythropoietic anemia type 1 with novel compound heterozygous CDAN1 mutations. Blood Cells Mol Dis, 71, 63-66. (Read full article)
    9. Velinder M, Singer J, Bareyan D, Meznarich J, Tracy CM, Fulcher JM, McClellan D, Lucente H, Franklin S, Sharma S, Engel ME (2016). GFI1 functions in transcriptional control and cell fate determination require SNAG domain methylation to recruit LSD1. Biochem J, 473(19), 3355-69. (Read full article)
    10. Meznarich J, Miles R, Paxton CN, Afify Z (2016). Pediatric B-Cell Lymphoma With Lymphoblastic Morphology, TdT Expression, MYC Rearrangement, and Features Overlapping With Burkitt Lymphoma. Pediatr Blood Cancer, 63(5), 938-40. (Read full article)
    11. Meznarich J, Malchodi L, Helterline D, Ramsey SA, Bertko K, Plummer T, Plawman A, Gold E, Stempien-Otero A (2013). Urokinase plasminogen activator induces pro-fibrotic/m2 phenotype in murine cardiac macrophages. PLoS One, 8(3), e57837. (Read full article)

    Review

    1. Christensen RD, Bahr TM, Ohls RK, Ilstrup SJ, Moise KJ Jr, Lopriore E, Meznarich JA (2024). Erythrokinetic mechanism(s) causing the "late anemia" of hemolytic disease of the fetus and newborn. [Review]. J Perinatol, 44(6), 916-919. (Read full article)

    Case Report

    1. Lozano Chinga M, Afify Z, Lowichik A, Grinsell MM, Seamon M, Meznarich JA (2022). Female adolescent with recurrent anemia and thrombocytopenia: Questions. Pediatr Nephrol, 37(9), 2067-2068. (Read full article)
    2. Lozano Chinga M, Afify Z, Lowichik A, Grinsell MM, Seamon M, Meznarich JA (2022). Female adolescent with recurrent anemia and thrombocytopenia: Answers. Pediatr Nephrol, 37(9), 2069-2071. (Read full article)
    3. Bahr TM, Lozano-Chinga M, Agarwal AM, Meznarich JA, Yost CC, Li P, Reading NS, Prchal JT, Christensen RD (2020). A Novel Variant in G6PD (c.1375C>G) Identified from a Hispanic Neonate with Extreme Hyperbilirubinemia and Low G6PD Enzymatic Activity. Neonatology, 117(4), 532-535. (Read full article)

    Letter

    1. Meznarich JA, Rets A, Agarwal AM, Christensen RD, Reading NS, Kuypers FA, Prchal JT (2021). Novel, de novo, beta-globin variant with decreased oxygen affinity (HBB:c.317T>A, "Hemoglobin St. George") in a healthy child with low oxygen saturations and anemia. [Letter to the editor]. Am J Hematol, 96(12), E448-E450. (Read full article)

    Abstract

    1. Giger Seu, K, Trump, L Emberesh, S, Lorsbach, R, Johnson, C, Meznarich, J, Underhill, H, Sakthivel, H, Niss, O, Nortman, S, Blanc, L, Zhang, W, Lutzko, C, and Kalfa, T (2019). VPS4A mutations Cause a Syndrome with Dyserythropoiesis, Hemolytic Anemia, and Neurodevelopmental Delay [Abstract]. 134(Supplement 1), 339.
    2. Niss, O Lorsbach, R, Buchbinder, D, Chonat, S, McLemore, M, McCavit, T, Schwartz, J, Meznarich, J, Seu, K, Zhang, W, Kalfa, T (2019). Congenital Dyserythropoietic Anemia Type 1 Due to Biallelic CDAN1 mutations: Report from the Congenital Dyserythropoietic Anemia Registry (CDAR) [Abstract]. 134(Supplement 1), 3521.
    3. Velinder M, Singer J, Meznarich J, Theisen E, Fulcher J, Tracy C, Franklin S, Sharma S, Engel M (2015). GFI1 Snag Domain Methylation Directs LSD1 Recruitment to Control Transcription and Cell Fate Determination in Hematopoiesis [Abstract]. Blood, 126(23).
  • Clinical Trials