Jessica A. Meznarich
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Jessica A. Meznarich, MD

Languages spoken: Mandarin Chinese, English

Clinical Locations

Primary Location

Primary Children's Hospital

100 N Mario Capecchi Drive
Salt Lake City , UT 84113
801-662-2900
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Dr. Meznarich received her medical degree from the University of Washington School of Medicine in Seattle, Washington. She then completed her residency in Pediatrics and fellowship in Pediatric Hematology and Oncology at the University of Utah/Primary Children’s Hospital in Salt Lake City, Utah.

She joined the faculty of the University of Utah in 2016, where she is currently an Associate Professor of Pediatrics in the Division of Pediatric Hematology and Oncology. Her clinical and research interests are in non-malignant hematology, bleeding disorders, thrombosis and clotting disorders, and hemoglobinopathies including thalassemia and sickle cell disease.

Specialties

Board Certification

American Board of Pediatrics (Sub: Pediatric Hematology-Oncology)
American Board of Pediatrics (Pediatrics)

Dr. Meznarich received her medical degree from the University of Washington School of Medicine in Seattle, Washington. She then completed her residency in Pediatrics and fellowship in Pediatric Hematology and Oncology at the University of Utah/Primary Children’s Hospital in Salt Lake City, Utah.

She joined the faculty of the University of Utah in 2016, where she is currently an Associate Professor of Pediatrics in the Division of Pediatric Hematology and Oncology. Her clinical and research interests are in non-malignant hematology, bleeding disorders, thrombosis and clotting disorders, and hemoglobinopathies including thalassemia and sickle cell disease.

Board Certification and Academic Information

Academic Departments Pediatrics -Associate Professor (Clinical)
Academic Divisions Hematology/Oncology
Board Certification
American Board of Pediatrics (Sub: Pediatric Hematology-Oncology)
American Board of Pediatrics (Pediatrics)

Education history

Undergraduate Biochemistry, Chemistry - University of Washington B.S.
Professional Medical Medicine - University of Washington School of Medicine M.D.
Residency Pediatrics - University of Utah School of Medicine Resident
Fellowship Pediatric Hematology-Oncology - University of Utah School of Medicine Fellow

Selected Publications

Journal Article

  1. Wen T, Boyden SE, Hocutt CM, Lewis RG, Baldwin EE, Vagher J, Andrews A, Nicholas TJ, Chapin A, Fan EM, Botto LD, Bayrak-Toydemir P, Mao R, Meznarich (2025). Identification of two novel non-coding variants in Diamond-Blackfan Anemia Syndrome patients by whole genome sequencing. Blood advances, 9(10), 2443-2452.
  2. Patel PK, Chinga ML, Yilmaz M, Joychan S, Ujhazi B, Ellison M, Gordon S, Nieves D, Csomos K, Eslin D, Afify ZA, Meznarich J, Bohnsack J, Walkovich K, Seidel MG, Sharapova S, Boyarchyk O, Latysheva E, Tuzankina I, Shaker AB, Ayala I, Sriaroon P, Westermann-Clark E, Walter J (2024). Clinical and Treatment History of Patients with Partial DiGeorge Syndrome and Autoimmune Cytopenia at Multiple Centers. Journal of clinical immunology, 44(2), 42.
  3. Lozano Chinga MM, Bussel JB, Fluchel MN, Wilkes J, Zhang C, Meeks H, Meznarich J (2024). Familial autoimmunity and risk of developing immune thrombocytopenia and Evans syndrome. Pediatric blood & cancer, 71(10), e31239.
  4. Song J, Lanikova L, Kim SJ, Papadopoulos N, Meznarich J, Constantinescu SN, Parsegov B, Prchal JF, Prchal J (2024). Novel germline JAK2(R715T) mutation causing PV-like erythrocytosis in 3 generations. Amelioration by Ropeg-Interferon. American journal of hematology, 99(7), 1220-1229.
  5. Fan EM, Vagher J, Meznarich JA, Ubico EM, Goteti S, Peterson D, Rayes A, Maese L (2023). Severe congenital neutropenia, SRP54 pathogenicity, and a framework for surveillance. American journal of medical genetics. Part A, 191(5), 1434-1441.
  6. Fan EM, Vagher J, Meznarich JA, Ubico EM, Goteti S, Peterson D, Rayes A, Maese L (2023). Severe congenital neutropenia, SRP54 pathogenicity, and a framework for surveillance. American journal of medical genetics. Part A, 191(5), 1434-1441.
  7. Aldag E, Fan EM, Marshall I, Christensen RD, Shayota BJ, Meznarich J (2022). An Infant With Hereditary Fructose Intolerance and a Novel Presentation of Disseminated Intravascular Coagulopathy Following Pyloromyotomy. Journal of pediatric hematology/oncology, 44(7), 409-411.
  8. Niss O, Lorsbach RB, Berger M, Chonat S, McLemore M, Buchbinder D, McCavit T, Shaffer LG, Simpson J, Schwartz JH, Meznarich J, Emberesh M, Seu KG, Zhang W, Kalfa TA, CDAR consortium (2021). Congenital dyserythropoietic anemia type I: First report from the Congenital Dyserythropoietic Anemia Registry of North America (CDAR). Blood cells, molecules & diseases, 87, 102534.
  9. Bahr TM, Agarwal AM, Meznarich JA, Prince WL, Wait TWP, Prchal JT, Christensen R (2021). Thirty-five males with severe (Class 1) G6PD deficiency (c.637G>T) in a North American family of European ancestry. Blood cells, molecules & diseases, 92, 102625.
  10. Seu KG, Trump LR, Emberesh S, Lorsbach RB, Johnson C, Meznarich J, Underhill HR, Chou ST, Sakthivel H, Nassar NN, Seu KJ, Blanc L, Zhang W, Lutzko CM, Kalfa TA (2020). VPS4A Mutations in Humans Cause Syndromic Congenital Dyserythropoietic Anemia due to Cytokinesis and Trafficking Defects. Am J Hum Genet, 107(6), 1149-1156.
  11. Bahr TM, Lozano-Chinga M, Agarwal AM, Meznarich JA, Gerday E, Smoot JL, Taylor A, Christensen R (2020). Dizygotic twins with prolonged jaundice and microcytic, hypochromic, hemolytic anemia with pyropoikilocytosis. Blood cells, molecules & diseases, 85, 102462.
  12. Bahr, TM, Knudsen, MC, Lozano-Chinga, M, Agarwal, AM, Meznarich, JA, Ohls, RK, Christensen, RD (2020). Infantile Pyknocytosis: End-Tidal CO, %Micro-R Measurements, Next-Generation Sequencing, and Transfusion Avoidance with Darbepoetin . 5,
  13. Meznarich JA, Draper L, Christensen RD, Yaish HM, Luem ND, Pysher TJ, Jung G, Nemeth E, Ganz T, Ward D (2018). Fetal presentation of congenital dyserythropoietic anemia type 1 with novel compound heterozygous CDAN1 mutations. Blood cells, molecules & diseases, 71, 63-66.
  14. Velinder M, Singer J, Bareyan D, Meznarich J, Tracy CM, Fulcher JM, McClellan D, Lucente H, Franklin S, Sharma S, Engel M (2016). GFI1 functions in transcriptional control and cell fate determination require SNAG domain methylation to recruit LSD1. The Biochemical journal, 473(19), 3355-69.
  15. Meznarich J, Miles R, Paxton CN, Afify (2016). Pediatric B-Cell Lymphoma With Lymphoblastic Morphology, TdT Expression, MYC Rearrangement, and Features Overlapping With Burkitt Lymphoma. Pediatric blood & cancer, 63(5), 938-40.
  16. Meznarich J, Malchodi L, Helterline D, Ramsey SA, Bertko K, Plummer T, Plawman A, Gold E, Stempien-Otero (2013). Urokinase plasminogen activator induces pro-fibrotic/m2 phenotype in murine cardiac macrophages. PloS one, 8(3), e57837.

Review

  1. Christensen RD, Bahr TM, Ohls RK, Ilstrup SJ, Moise KJ Jr, Lopriore E, Meznarich J (2024). Erythrokinetic mechanism(s) causing the "late anemia" of hemolytic disease of the fetus and newborn. Journal of perinatology, 44(6), 916-919.

Case Report

  1. Lozano Chinga M, Afify Z, Lowichik A, Grinsell MM, Seamon M, Meznarich J (2022). Female adolescent with recurrent anemia and thrombocytopenia: Questions. Pediatric nephrology (Berlin, Germany), 37(9), 2067-2068.
  2. Lozano Chinga M, Afify Z, Lowichik A, Grinsell MM, Seamon M, Meznarich J (2022). Female adolescent with recurrent anemia and thrombocytopenia: Answers. Pediatric nephrology (Berlin, Germany), 37(9), 2069-2071.
  3. Bahr TM, Lozano-Chinga M, Agarwal AM, Meznarich JA, Yost CC, Li P, Reading NS, Prchal JT, Christensen R (2020). A Novel Variant in G6PD (c.1375C>G) Identified from a Hispanic Neonate with Extreme Hyperbilirubinemia and Low G6PD Enzymatic Activity. Neonatology, 117(4), 532-535.

Letter

  1. Meznarich JA, Rets A, Agarwal AM, Christensen RD, Reading NS, Kuypers FA, Prchal JT (2021). Novel, de novo, beta-globin variant with decreased oxygen affinity (HBB:c.317T>A, "Hemoglobin St. George") in a healthy child with low oxygen saturations and anemia. [Letter to the editor]. Am J Hematol, 96(12), E448-E450.

Abstract

  1. Giger Seu, K., Trump, L. Emberesh, S., Lorsbach, R., Johnson, C., Meznarich, J., Underhill, H., Sakthivel, H., Niss, O., Nortman, S., Blanc, L, Zhang, W., Lutzko, C., and Kalfa, T (2019). VPS4A mutations Cause a Syndrome with Dyserythropoiesis, Hemolytic Anemia, and Neurodevelopmental Delay. 134(Supplement 1), 339.
  2. Niss, O. Lorsbach, R., Buchbinder, D., Chonat, S., McLemore, M., McCavit, T., Schwartz, J., Meznarich, J., Seu, K., Zhang, W., Kalfa, (2019). Congenital Dyserythropoietic Anemia Type 1 Due to Biallelic CDAN1 mutations: Report from the Congenital Dyserythropoietic Anemia Registry (CDAR). 134(Supplement 1), 3521.
  3. Velinder M, Singer J, Meznarich J, Theisen E, Fulcher J, Tracy C, Franklin S, Sharma S, Engel (2015). GFI1 Snag Domain Methylation Directs LSD1 Recruitment to Control Transcription and Cell Fate Determination in Hematopoiesis. Blood, 126(23),