Kristin M. Leiferman
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Kristin M. Leiferman, MD

Languages spoken: English

  • Kristin M. Leiferman, M.D. is a Dermatologist and Immunodermatologist with expertise in immune-mediated skin diseases, especially diagnosis and management of allergic skin diseases and diagnosis of autoimmune blistering diseases that affect skin and mucous membranes. She has board certification in Dermatology and Dermatological Immunology/Diagnostic and Laboratory Immunology.

    Dr. Leiferman is Professor of Dermatology and Co-Director of the Immunodermatology Laboratory at the University of Utah, and has examined thousands of specimens for diagnosing autoimmune blistering diseases.

    Although her specialized focus is on allergy-related inflammation, including mast cell- and eosinophil-associated diseases, and laboratory diagnosis, she is passionate about skin health in general, from acne to skin cancer, prevention and treatment.

    Specialties

    Board Certification

    American Board of Dermatology (Dermatology)
    American Board of Dermatology (Sub: Clin&Lab Derm Imm)
    National Board of Medical Examiners

  • Kristin M. Leiferman, M.D. is a Dermatologist and Immunodermatologist with expertise in immune-mediated skin diseases, especially diagnosis and management of allergic skin diseases and diagnosis of autoimmune blistering diseases that affect skin and mucous membranes. She has board certification in Dermatology and Dermatological Immunology/Diagnostic and Laboratory Immunology.

    Dr. Leiferman is Professor of Dermatology and Co-Director of the Immunodermatology Laboratory at the University of Utah, and has examined thousands of specimens for diagnosing autoimmune blistering diseases.

    Although her specialized focus is on allergy-related inflammation, including mast cell- and eosinophil-associated diseases, and laboratory diagnosis, she is passionate about skin health in general, from acne to skin cancer, prevention and treatment.

    Board Certification and Academic Information

    Academic Departments Dermatology -Professor
    Pathology -Adjunct Professor
    Board Certification
    American Board of Dermatology (Dermatology)
    American Board of Dermatology (Sub: Clin&Lab Derm Imm)
    National Board of Medical Examiners

    Education history

    Residency Dermatology - Mayo Clinic Resident
    Professional Medical Medicine - Mayo Medical School M.D.
    Undergraduate Biology - University of Minnesota B.S.

    Selected Publications

    Journal Article

    1. Lehman JS, Fernandez AP, Leiferman KM, Brinster NK, Culton DA, Kim RH, North JP, Stoff BK, Camilleri MJ, Cocks MM, Elenitsas R, Fung MA, Grover RK, Jedrych JJ, Kuechle MK, McNiff JM, Moshiri AS, Motaparthi K, Murphy MJ, Nousari CH, Shalin SC, Zone JJ, Bridges AG (2025). Assessment of Cutaneous and Mucosal Direct Immunofluorescence Testing Practices in the US. JAMA Dermatol. (Read full article)
    2. Yun S, Jenkins BA, Scollan ME, Defelice AR, Leiferman KM, Milner JD, Lauren CT (2024). Pemphigus Vulgaris With Esophageal Involvement in an Atopic Child Successfully Treated With Dupilumab. Pediatr Dermatol, 42(2), 371-375. (Read full article)
    3. Leiferman KM, Snook JP, Khalighi MA, Kuechle MK, Zone JJ (2021). Diagnostics for Dermatologic Diseases with Autoantibodies. J Appl Lab Med, 7(1), 165-196. (Read full article)
    4. Saffari H, Peterson KA, Leiferman KM, Stabin MG, Krstyen JJ, Clayton FC, Pease LF 3rd, Yap JT, Hoffman JM, Gleich GJ (2019). Oral Administration of 99mTechnetium-Labeled Heparin in Eosinophilic Esophagitis. Mayo Clin Proc, 95(3), 449-458. (Read full article)
    5. Peterson KA, Gleich GJ, Limaye NS, Crispin H, Robson J, Fang J, Saffari H, Clayton F, Leiferman KM (2019). Eosinophil granule major basic protein 1 deposition in eosinophilic esophagitis correlates with symptoms independent of eosinophil counts. Dis Esophagus, 32(11). (Read full article)
    6. Mao X, Nagler AR, Farber SA, Choi EJ, Jackson LH, Leiferman KM, Ishii N, Hashimoto T, Amagai M, Zone JJ, Payne AS (2010). Autoimmunity to desmocollin 3 in pemphigus vulgaris. Am J Pathol, 177(6), 2724-30. (Read full article)
    7. Plager DA, Davis MD, Andrews AG, Coenen MJ, George TJ, Gleich GJ, Leiferman KM (2009). Eosinophil ribonucleases and their cutaneous lesion-forming activity. J Immunol, 183(6), 4013-20. (Read full article)
    8. Donaldson MR, Firth SD, Wimpee H, Leiferman KM, Zone JJ, Horsley W, OGorman MA, Jackson WD, Neuhausen SL, Hull CM, Book LS (2007). Correlation of duodenal histology with tissue transglutaminase and endomysial antibody levels in pediatric celiac disease. Clin Gastroenterol Hepatol, 5(5), 567-73. (Read full article)
    9. Plager DA, Weiss EA, Kephart GM, Mocharla RM, Matsumoto R, Checkel JL, Schwartz LB, Gleich GJ, Leiferman KM (2006). Identification of basophils by a mAb directed against pro-major basic protein 1. J Allergy Clin Immunol, 117(3), 626-34. (Read full article)
    10. Davis MD, Plager DA, George TJ, Weiss EA, Gleich GJ, Leiferman KM (2003). Interactions of eosinophil granule proteins with skin: limits of detection, persistence, and vasopermeabilization. J Allergy Clin Immunol, 112(5), 988-94. (Read full article)
    11. Trocme SD, Leiferman KM, George T, Bonini S, Foster CS, Smit EE, Sra SK, Grabowski LR, Dohlman CH (2003). Neutrophil and eosinophil participation in atopic and vernal keratoconjunctivitis. Curr Eye Res, 26(6), 319-25. (Read full article)
    12. Drage LA, Davis MD, De Castro F, Van Keulen V, Weiss EA, Gleich GJ, Leiferman KM (2002). Evidence for pathogenic involvementof eosinophils and neutrophilsin Churg-Strauss syndrome. J Am Acad Dermatol, 47(2), 209-16. (Read full article)
    13. Sami N, Bhol KC, Beutner EH, Plunkett RW, Leiferman KM, Foster CS, Ahmed AR (2001). Simultaneous presence of mucous membrane pemphigoid and pemphigus vulgaris: molecular characterization of both autoantibodies. Clin Immunol, 100(2), 219-27. (Read full article)
    14. Khan DA, Cody DT 2nd, George TJ, Gleich GJ, Leiferman KM (2000). Allergic fungal sinusitis: an immunohistologic analysis. J Allergy Clin Immunol, 106(6), 1096-101. (Read full article)
    15. Sanico AM, Kita H, Leiferman KM, Saini SS (1999). Eosinophilia in a 23-year-old woman with asthma. Ann Allergy Asthma Immunol, 83(3), 193-9. (Read full article)
    16. Chen KR, Pittelkow MR, Su D, Gleich J, Newman W, Leiferman KM (1994). Recurrent cutaneous necrotizing eosinophilic vasculitis. A novel eosinophil-mediated syndrome. Arch Dermatol, 130(9), 1159-66. (Read full article)
    17. Mehregan DR, Oursler JR, Leiferman KM, Muller SA, Anhalt GJ, Peters MS (1993). Paraneoplastic pemphigus: a subset of patients with pemphigus and neoplasia. J Cutan Pathol, 20(3), 203-10. (Read full article)
    18. Mehregan DR, Fransway AF, Edmonson JH, Leiferman KM (1992). Cutaneous reactions to granulocyte-monocyte colony-stimulating factor. Arch Dermatol, 128(8), 1055-9. (Read full article)
    19. Leiferman KM, Groover RV, Dicken CH (1984). Acne fulminans and myositis. Cutis, 34(3), 249-51. (Read full article)
    20. Smalley SR, Rubin J, Leiferman KM (1984). Neurofibrosarcoma and the sign of Leser-Trélat. CA Cancer J Clin, 34(5), 295-8. (Read full article)

    Review

    1. Leiferman KM, Gleich GJ (2023). The true extent of eosinophil involvement in disease is unrecognized: the secret life of dead eosinophils. [Review]. J Leukoc Biol, 116(2), 271-287. (Read full article)
    2. Valent P, Klion AD, Roufosse F, Simon D, Metzgeroth G, Leiferman KM, Schwaab J, Butterfield JH, Sperr WR, Sotlar K, Vandenberghe P, Hoermann G, Haferlach T, Moriggl R, George TI, Akin C, Bochner BS, Gotlib J, Reiter A, Horny HP, Arock M, Simon HU, Gleich GJ (2022). Proposed refined diagnostic criteria and classification of eosinophil disorders and related syndromes. [Review]. Allergy, 78(1), 47-59. (Read full article)
    3. Valent P, Klion AD, Horny HP, Roufosse F, Gotlib J, Weller PF, Hellmann A, Metzgeroth G, Leiferman KM, Arock M, Butterfield JH, Sperr WR, Sotlar K, Vandenberghe P, Haferlach T, Simon HU, Reiter A, Gleich GJ (2012). Contemporary consensus proposal on criteria and classification of eosinophilic disorders and related syndromes. [Review]. J Allergy Clin Immunol, 130(3), 607-612.e9. (Read full article)
    4. Gleich GJ, Leiferman KM (2009). The hypereosinophilic syndromes: current concepts and treatments. [Review]. Br J Haematol, 145(3), 271-85. (Read full article)

    Case Report

    1. Jimenez A, Topham C, Varedi D, Leiferman KM, Hull C (2021). Mucosal linear IgA disease with esophageal involvement responsive to ustekinumab. JAAD Case Rep, 15, 4-6. (Read full article)

    Editorial

    1. Gleich GJ, Leiferman KM (2022). Does Eosinophil Depletion in Gastroenteric Diseases Associated With the Hypereosinophilic Syndrome Teach Us Whether Normal Humans Need Eosinophils in 2022? J Allergy Clin Immunol Pract, 10(6), 1606-1607. (Read full article)

    Letter

    1. Gleich GJ, Leiferman KM (2021). Are Eosinophils Needed for Normal Health? [Letter to the editor]. Mayo Clin Proc, 97(4), 805. (Read full article)