Kristin M. Leiferman
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Kristin M. Leiferman, MD

Languages spoken: English

  • Kristin M. Leiferman, M.D. is a Dermatologist and Immunodermatologist with expertise in immune-mediated skin diseases, especially diagnosis and management of allergic skin diseases and diagnosis of autoimmune blistering diseases that affect skin and mucous membranes. She has board certification in Dermatology and Dermatological Immunology/Diagnostic and Laboratory Immunology.

    Dr. Leiferman is Professor of Dermatology and Co-Director of the Immunodermatology Laboratory at the University of Utah, and has examined thousands of specimens for diagnosing autoimmune blistering diseases.

    Although her specialized focus is on allergy-related inflammation, including mast cell- and eosinophil-associated diseases, and laboratory diagnosis, she is passionate about skin health in general, from acne to skin cancer, prevention and treatment.

    Specialties

    Board Certification

    American Board of Dermatology (Sub: Clin&Lab Derm Imm)
    American Board of Dermatology (Dermatology)
    National Board of Medical Examiners

  • Kristin M. Leiferman, M.D. is a Dermatologist and Immunodermatologist with expertise in immune-mediated skin diseases, especially diagnosis and management of allergic skin diseases and diagnosis of autoimmune blistering diseases that affect skin and mucous membranes. She has board certification in Dermatology and Dermatological Immunology/Diagnostic and Laboratory Immunology.

    Dr. Leiferman is Professor of Dermatology and Co-Director of the Immunodermatology Laboratory at the University of Utah, and has examined thousands of specimens for diagnosing autoimmune blistering diseases.

    Although her specialized focus is on allergy-related inflammation, including mast cell- and eosinophil-associated diseases, and laboratory diagnosis, she is passionate about skin health in general, from acne to skin cancer, prevention and treatment.

    Board Certification and Academic Information

    Academic Departments Dermatology -Professor
    Pathology -Adjunct Professor
    Board Certification
    American Board of Dermatology (Sub: Clin&Lab Derm Imm)
    American Board of Dermatology (Dermatology)
    National Board of Medical Examiners

    Education history

    Undergraduate Biology - University of Minnesota B.S.
    Professional Medical Medicine - Mayo Medical School M.D.
    Residency Dermatology - Mayo Clinic Resident

    Selected Publications

    Journal Article

    1. Mao X, Nagler AR, Farber SA, Choi EJ, Jackson LH, Leiferman KM, Ishii N, Hashimoto T, Amagai M, Zone JJ, Payne A (2010). Autoimmunity to desmocollin 3 in pemphigus vulgaris. The American journal of pathology, 177(6), 2724-30. (Read full publication)
    2. Trocme SD, Leiferman KM, George T, Bonini S, Foster CS, Smit EE, Sra SK, Grabowski LR, Dohlman C (2003). Neutrophil and eosinophil participation in atopic and vernal keratoconjunctivitis. Current eye research, 26(6), 319-25. (Read full publication)
    3. Khan DA, Cody DT 2nd, George TJ, Gleich GJ, Leiferman K (2000). Allergic fungal sinusitis: an immunohistologic analysis. The Journal of allergy and clinical immunology, 106(6), 1096-101. (Read full publication)
    4. Davis MD, Plager DA, George TJ, Weiss EA, Gleich GJ, Leiferman K (2003). Interactions of eosinophil granule proteins with skin: limits of detection, persistence, and vasopermeabilization. The Journal of allergy and clinical immunology, 112(5), 988-94. (Read full publication)
    5. Plager DA, Weiss EA, Kephart GM, Mocharla RM, Matsumoto R, Checkel JL, Schwartz LB, Gleich GJ, Leiferman K (2006). Identification of basophils by a mAb directed against pro-major basic protein 1. The Journal of allergy and clinical immunology, 117(3), 626-34. (Read full publication)
    6. Drage LA, Davis MD, De Castro F, Van Keulen V, Weiss EA, Gleich GJ, Leiferman K (2002). Evidence for pathogenic involvementof eosinophils and neutrophilsin Churg-Strauss syndrome. Journal of the American Academy of Dermatology, 47(2), 209-16. (Read full publication)
    7. Plager DA, Davis MD, Andrews AG, Coenen MJ, George TJ, Gleich GJ, Leiferman K (2009). Eosinophil ribonucleases and their cutaneous lesion-forming activity. Journal of immunology (Baltimore, Md., 183(6), 4013-20. (Read full publication)
    8. Saffari H, Peterson KA, Leiferman KM, Stabin MG, Krstyen JJ, Clayton FC, Pease LF 3rd, Yap JT, Hoffman JM, Gleich G (2020). Oral Administration of 99mTechnetium-Labeled Heparin in Eosinophilic Esophagitis. Mayo Clinic proceedings, 95(3), 449-458. (Read full publication)
    9. Peterson KA, Gleich GJ, Limaye NS, Crispin H, Robson J, Fang J, Saffari H, Clayton F, Leiferman K (2019). Eosinophil granule major basic protein 1 deposition in eosinophilic esophagitis correlates with symptoms independent of eosinophil counts. Diseases of the esophagus, 32(11), (Read full publication)
    10. Donaldson MR, Firth SD, Wimpee H, Leiferman KM, Zone JJ, Horsley W, O'Gorman MA, Jackson WD, Neuhausen SL, Hull CM, Book L (2007). Correlation of duodenal histology with tissue transglutaminase and endomysial antibody levels in pediatric celiac disease. Clinical gastroenterology and hepatology, 5(5), 567-73. (Read full publication)
    11. Lehman JS, Fernandez AP, Leiferman KM, Brinster NK, Culton DA, Kim RH, North JP, Stoff BK, Camilleri MJ, Cocks MM, Elenitsas R, Fung MA, Grover RK, Jedrych JJ, Kuechle MK, McNiff JM, Moshiri AS, Motaparthi K, Murphy MJ, Nousari CH, Shalin SC, Zone JJ, Bridges A (2025). Assessment of Cutaneous and Mucosal Direct Immunofluorescence Testing Practices in the US. JAMA dermatology, 161(7), 747-754. (Read full publication)
    12. Smalley SR, Rubin J, Leiferman K (1984). Neurofibrosarcoma and the sign of Leser-Trélat. CA, 34(5), 295-8. (Read full publication)
    13. Mehregan DR, Fransway AF, Edmonson JH, Leiferman K (1992). Cutaneous reactions to granulocyte-monocyte colony-stimulating factor. Archives of dermatology, 128(8), 1055-9. (Read full publication)
    14. Mehregan DR, Oursler JR, Leiferman KM, Muller SA, Anhalt GJ, Peters M (1993). Paraneoplastic pemphigus: a subset of patients with pemphigus and neoplasia. Journal of cutaneous pathology, 20(3), 203-10. (Read full publication)
    15. Chen KR, Pittelkow MR, Su D, Gleich J, Newman W, Leiferman K (1994). Recurrent cutaneous necrotizing eosinophilic vasculitis. A novel eosinophil-mediated syndrome. Archives of dermatology, 130(9), 1159-66. (Read full publication)
    16. Sami N, Bhol KC, Beutner EH, Plunkett RW, Leiferman KM, Foster CS, Ahmed A (2001). Simultaneous presence of mucous membrane pemphigoid and pemphigus vulgaris: molecular characterization of both autoantibodies. Clinical immunology (Orlando, Fla.), 100(2), 219-27. (Read full publication)
    17. Leiferman KM, Groover RV, Dicken C (1984). Acne fulminans and myositis. Cutis, 34(3), 249-51. (Read full publication)

    Review

    1. Gleich GJ, Leiferman K (2009). The hypereosinophilic syndromes: current concepts and treatments. British journal of haematology, 145(3), 271-85. (Read full publication)
    2. Valent P, Klion AD, Horny HP, Roufosse F, Gotlib J, Weller PF, Hellmann A, Metzgeroth G, Leiferman KM, Arock M, Butterfield JH, Sperr WR, Sotlar K, Vandenberghe P, Haferlach T, Simon HU, Reiter A, Gleich G (2012). Contemporary consensus proposal on criteria and classification of eosinophilic disorders and related syndromes. The Journal of allergy and clinical immunology, 130(3), 607-612.e9. (Read full publication)
    3. Valent P, Klion AD, Roufosse F, Simon D, Metzgeroth G, Leiferman KM, Schwaab J, Butterfield JH, Sperr WR, Sotlar K, Vandenberghe P, Hoermann G, Haferlach T, Moriggl R, George TI, Akin C, Bochner BS, Gotlib J, Reiter A, Horny HP, Arock M, Simon HU, Gleich G (2023). Proposed refined diagnostic criteria and classification of eosinophil disorders and related syndromes. Allergy, 78(1), 47-59. (Read full publication)
    4. Leiferman KM, Gleich G (2024). The true extent of eosinophil involvement in disease is unrecognized: the secret life of dead eosinophils. Journal of leukocyte biology, 116(2), 271-287. (Read full publication)

    Case Report

    1. Jimenez A, Topham C, Varedi D, Leiferman KM, Hull (2021). Mucosal linear IgA disease with esophageal involvement responsive to ustekinumab. JAAD case reports, 15, 4-6. (Read full publication)
    2. Yun S, Jenkins BA, Scollan ME, Defelice AR, Leiferman KM, Milner JD, Lauren C (2025). Pemphigus Vulgaris With Esophageal Involvement in an Atopic Child Successfully Treated With Dupilumab. Pediatric dermatology, 42(2), 371-375. (Read full publication)
    3. Sanico AM, Kita H, Leiferman KM, Saini S (1999). Eosinophilia in a 23-year-old woman with asthma. Annals of allergy, asthma & immunology, 83(3), 193-9. (Read full publication)

    Editorial

    1. Gleich GJ, Leiferman K (2022). Does Eosinophil Depletion in Gastroenteric Diseases Associated With the Hypereosinophilic Syndrome Teach Us Whether Normal Humans Need Eosinophils in 2022?. The journal of allergy and clinical immunology. In practice, 10(6), 1606-1607. (Read full publication)

    Letter

    1. Gleich GJ, Leiferman K (2022). Are Eosinophils Needed for Normal Health?. Mayo Clinic proceedings, 97(4), 805. (Read full publication)