Laurie W. Leclair
Rating: 4.9 of 5
( out of 24 reviews )

Laurie W. Leclair, MD

Languages spoken: English

Clinical Locations

Primary Location

Sugar House Health Center

1280 E. Stringham Avenue
Salt Lake City , UT 84106
801-581-2000
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University of Utah Hospital

Lung Transplant, Clinic 3
50 N Medical Dr
Salt Lake City , UT 84132
801-585-3697
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  • Dr. Leclair specializes in lung transplantation and cystic fibrosis. She completed her medical degree at Tufts University, followed by residency at the University of Colorado and a fellowship at Yale University. She joined the faculty at the University of Utah in 2019 from the University of Vermont. In addition to her clinical work she an Assistant Dean of Curriculum and is responsible for the oversight of all coursework within the clinical curriculum.

    Specialties

    Board Certification

    American Board of Internal Medicine
    American Board of Internal Medicine (Sub: Critical Care Medicine)
    American Board of Internal Medicine (Sub: Pulmonary Disease)

    Patient Rating

    Rating: 4.9 out of 5
    4.9 /5
    ( out of 24 reviews )

    The patient rating score is an average of all responses on our patient experience survey. The rating averages scores for all questions about care from our providers.

    The scale on which responses are measured is 1 to 5 with 5 being the best score.

    Patient Comments

    Patient comments are gathered from our patient experience survey and displayed in their entirety. For the convenience of our visitors, some patient comments have been translated from their original language into English while preserving their original meaning as accurately as possible. Patients are de-identified for confidentiality and patient privacy.

    September 20, 2024
    SUGAR HOUSE HEALTH CENTER
    Rating: 5 out of 5

    Great doctor really keeps me in the best health possible. Always tried to find solutions to my health problems.

    March 29, 2024
    SUGAR HOUSE HEALTH CENTER
    Rating: 5 out of 5

    Dr. LeClair and staff take very good of you.

  • Dr. Leclair specializes in lung transplantation and cystic fibrosis. She completed her medical degree at Tufts University, followed by residency at the University of Colorado and a fellowship at Yale University. She joined the faculty at the University of Utah in 2019 from the University of Vermont. In addition to her clinical work she an Assistant Dean of Curriculum and is responsible for the oversight of all coursework within the clinical curriculum.

    Board Certification and Academic Information

    Academic Departments Internal Medicine -Professor (Clinical)
    Academic Divisions Public Health
    Board Certification
    American Board of Internal Medicine
    American Board of Internal Medicine (Sub: Critical Care Medicine)
    American Board of Internal Medicine (Sub: Pulmonary Disease)

    Education history

    Postdoctoral Fellowship Pulmonary and Critical Care Medicine - Yale School of Medicine Postdoctoral Fellow
    Internship/Residency Internal Medicine - University of Colorado Health Sciences Center Intern/Resident
    Professional Medical Medicine - Tufts University School of Medicine M.D.
    Undergraduate Chemistry - University of Vermont B.A.

    Selected Publications

    Journal Article

    1. Lindley B, Bhakta Z, Leclair L, Young DC (2023). The pharmacokinetics and pharmacodynamics of continuous infusion vancomycin in adult people with cystic fibrosis. Pediatr Pulmonol, 59(1), 89-94.
    2. Lindley B, Bhakta Z, Gray K, Watanabe A, Leclair L, Young DC (2022). Pharmacokinetics of intermittent dosed intravenous vancomycin in adult persons with cystic fibrosis. Pediatr Pulmonol, 57(11), 2646-2651. (Read full publication)
    3. Amarbir S Gill, Abigail Pulsipher, Jorgen S Sumsion, Gretchen M Oakley, Laurie W Leclair, Heather Howe, Richard R Orlandi, Jeremiah A Alt (2021). Transcriptional Changes in Chronic Rhinosinusitis with Asthma Favor a Type 2 Molecular Endotype Independent of Polyp Status. J Asthma Allergy, 14, 405-13.
    4. Gill AS, Pulsipher A, Sumsion JS, Oakley GM, Leclair LW, Howe H, Orlandi RR, Alt JA (2021). Transcriptional Changes in Chronic Rhinosinusitis with Asthma Favor a Type 2 Molecular Endotype Independent of Polyp Status. J Asthma Allergy, 14, 405-413. (Read full publication)
    5. Leclair LW, Dawson M, Howe A, Hale S, Zelman E, Clouser R, Garrison G, Allen G (2018). A longitudinal interprofessional simulation curriculum for critical care teams: Exploring successes and challenges. J Interprof Care, 32(3), 386-390. (Read full publication)
    6. Griswold KE, Bement JL, Teneback CC, Scanlon TC, Wargo MJ, Leclair LW (2014). Bioengineered lysozyme in combination therapies for Pseudomonas aeruginosa lung infections. Bioengineered, 5(2), 143-7. (Read full publication)
    7. Anathy V, Aesif SW, Hoffman SM, Bement JL, Guala AS, Lahue KG, Leclair LW, Suratt BT, Cool CD, Wargo MJ, Janssen-Heininger YM (2014). Glutaredoxin-1 attenuates S-glutathionylation of the death receptor fas and decreases resolution of Pseudomonas aeruginosa pneumonia. Am J Respir Crit Care Med, 189(4), 463-74. (Read full publication)
    8. Teneback CC, Scanlon TC, Wargo MJ, Bement JL, Griswold KE, Leclair LW (2013). Bioengineered lysozyme reduces bacterial burden and inflammation in a murine model of mucoid Pseudomonas aeruginosa lung infection. Antimicrob Agents Chemother, 57(11), 5559-64. (Read full publication)
    9. Zhu J, Bean HD, Wargo MJ, Leclair LW, Hill JE (2013). Detecting bacterial lung infections: in vivo evaluation of in vitro volatile fingerprints. J Breath Res, 7(1), 016003. (Read full publication)
    10. Entezari M, Weiss DJ, Sitapara R, Whittaker L, Wargo MJ, Li J, Wang H, Yang H, Sharma L, Phan BD, Javdan M, Chavan SS, Miller EJ, Tracey KJ, Mantell LL (2012). Inhibition of high-mobility group box 1 protein (HMGB1) enhances bacterial clearance and protects against Pseudomonas Aeruginosa pneumonia in cystic fibrosis. Mol Med, 18, 477-85. (Read full publication)
    11. Neveu WA, Bernardo E, Allard JL, Nagaleekar V, Wargo MJ, Davis RJ, Iwakura Y, Whittaker LA, Rincon M (2011). Fungal allergen beta-glucans trigger p38 mitogen-activated protein kinase-mediated IL-6 translation in lung epithelial cells. Am J Respir Cell Mol Biol, 45(6), 1133-41. (Read full publication)
    12. Wargo MJ, Gross MJ, Rajamani S, Allard JL, Lundblad LK, Allen GB, Vasil ML, Leclair LW, Hogan DA (2011). Hemolytic phospholipase C inhibition protects lung function during Pseudomonas aeruginosa infection. Am J Respir Crit Care Med, 184(3), 345-54. (Read full publication)
    13. Goodwin M, Sueblinvong V, Eisenhauer P, Ziats NP, LeClair L, Poynter ME, Steele C, Rincon M, Weiss DJ (2011). Bone marrow-derived mesenchymal stromal cells inhibit Th2-mediated allergic airways inflammation in mice. Stem Cells, 29(7), 1137-48. (Read full publication)
    14. Scanlon TC, Teneback CC, Gill A, Bement JL, Weiner JA, Lamppa JW, Leclair LW, Griswold KE (2010). Enhanced antimicrobial activity of engineered human lysozyme. ACS Chem Biol, 5(9), 809-18. (Read full publication)
    15. Hodgkins SR, Ather JL, Paveglio SA, Allard JL, LeClair LA, Suratt BT, Boyson JE, Poynter ME (2010). NO2 inhalation induces maturation of pulmonary CD11c+ cells that promote antigenspecific CD4+ T cell polarization. Respir Res, 11, 102. (Read full publication)
    16. Neveu WA, Allard JB, Dienz O, Wargo MJ, Ciliberto G, Whittaker LA, Rincon M (2009). IL-6 is required for airway mucus production induced by inhaled fungal allergens. J Immunol, 183(3), 1732-8. (Read full publication)
    17. Suratt BT, Eisner MD, Calfee CS, Allard JB, Whittaker LA, Engelken DT, Petty JM, Trimarchi T, Gauthier L, Parsons PE (2009). Plasma granulocyte colony-stimulating factor levels correlate with clinical outcomes in patients with acute lung injury. Crit Care Med, 37(4), 1322-8. (Read full publication)
    18. Allard JB, Rinaldi L, Wargo MJ, Allen G, Akira S, Uematsu S, Poynter ME, Hogan DA, Rincon M, Whittaker LA (2009). Th2 allergic immune response to inhaled fungal antigens is modulated by TLR-4-independent bacterial products. Eur J Immunol, 39(3), 776-88. (Read full publication)
    19. Wargo MJ, Ho TC, Gross MJ, Whittaker LA, Hogan DA (2009). GbdR regulates Pseudomonas aeruginosa plcH and pchP transcription in response to choline catabolites. Infect Immun, 77(3), 1103-11. (Read full publication)
    20. Pantano C, Ather JL, Alcorn JF, Poynter ME, Brown AL, Guala AS, Beuschel SL, Allen GB, Whittaker LA, Bevelander M, Irvin CG, Janssen-Heininger YM (2008). Nuclear factor-kappaB activation in airway epithelium induces inflammation and hyperresponsiveness. Am J Respir Crit Care Med, 177(9), 959-69. (Read full publication)
    21. Bevelander M, Mayette J, Whittaker LA, Paveglio SA, Jones CC, Robbins J, Hemenway D, Akira S, Uematsu S, Poynter ME (2007). Nitrogen dioxide promotes allergic sensitization to inhaled antigen. J Immunol, 179(6), 3680-8. (Read full publication)
    22. Paveglio SA, Allard J, Mayette J, Whittaker LA, Juncadella I, Anguita J, Poynter ME (2007). The tick salivary protein, Salp15, inhibits the development of experimental asthma. J Immunol, 178(11), 7064-71. (Read full publication)
    23. Allard JB, Poynter ME, Marr KA, Cohn L, Rincon M, Whittaker LA (2006). Aspergillus fumigatus generates an enhanced Th2-biased immune response in mice with defective cystic fibrosis transmembrane conductance regulator. J Immunol, 177(8), 5186-94. (Read full publication)
    24. Kostyk AG, Dahl KM, Wynes MW, Whittaker LA, Weiss DJ, Loi R, Riches DW (2006). Regulation of chemokine expression by NaCl occurs independently of cystic fibrosis transmembrane conductance regulator in macrophages. Am J Pathol, 169(1), 12-20. (Read full publication)
    25. Whittaker L, Niu N, Temann UA, Stoddard A, Flavell RA, Ray A, Homer RJ, Cohn L (2002). Interleukin-13 mediates a fundamental pathway for airway epithelial mucus induced by CD4 T cells and interleukin-9. Am J Respir Cell Mol Biol, 27(5), 593-602. (Read full publication)
    26. Whittaker LA, Cohn L (2002). Recent Concepts in the Pathogenesis and Treatment of Asthma. Clin Pulm Med, 9(3), 135-44.
    27. Cohn L, Whittaker L, Niu N, Homer RJ (2002). Cytokine regulation of mucus production in a model of allergic asthma. Novartis Found Symp, 248, 201-13; discussion 213-20, 277-82. (Read full publication)

    Review

    1. Leclair LW, Hogan DA (2010). Mixed bacterial-fungal infections in the CF respiratory tract. [Review]. Med Mycol, 48 Suppl 1, S125-32. (Read full publication)
    2. Whittaker LA, Teneback C (2009). Atypical mycobacterial and fungal infections in cystic fibrosis. [Review]. Semin Respir Crit Care Med, 30(5), 539-46. (Read full publication)
    3. Sueblinvong V, Whittaker LA (2007). Fertility and pregnancy: common concerns of the aging cystic fibrosis population. [Review]. Clin Chest Med, 28(2), 433-43. (Read full publication)
    4. Sueblinvong V, Whittaker LA (2006). Management Issues in Women with Cystic Fibrosis. [Review]. 9(6), 24.
    5. Whittaker LA, Kaminsky D (2006). Respiratory Physiology in Extreme Environments. [Review]. Clin Pulm Med, 13(5), 282-8.

    Case Report

    1. Whittaker LA, Bisognano JD (2001). Right-Sided Heart Failure and Severe Tricuspid Regurgitation After Mediastinal Radiation. Cardiovasc Rev Rep, 22(1), 23-5.

    Editorial

    1. Whittaker LA, Irvin CG (2007). Going to extremes of lung volume. J Appl Physiol (1985), 102(3), 831-3. (Read full publication)

    Letter

    1. Gonzalez KD, Zuckerman JB, Sears EH, Prato BS, Guill M, Craig W, Milliard C, Parker E, Lever T, Griffin MM, Leclair LW (2017). Exploring probiotic use in a regional cystic fibrosis consortium. [Letter to the editor]. J Cyst Fibros, 17(2), e20-e21. (Read full publication)
    2. Zuckerman JB, Clock SA, Prato BS, McDevitt JJ, Zhou JJ, Leclair LW, Lucas FL, Saiman L (2015). Air contamination with bacteria in cystic fibrosis clinics: implications for prevention strategies. [Letter to the editor]. Am J Respir Crit Care Med, 191(5), 598-601. (Read full publication)

    Other

    1. Gill AS, Smith KA, Meeks H, Oakley GM, Curtin K, Leclair L, Howe H, Orlandi RR, Alt JA (2021). Asthma increases long-term revision rates of endoscopic sinus surgery in chronic rhinosinusitis with and without nasal polyposis. Int Forum Allergy Rhinol (11(8), pp. 1197-1206). United States. (Read full publication)
    2. Whittaker LA (2005). Recent Advances in Cystic Fibrosis. Pulmonary and Critical Care Update (19, Lesson 1).
    3. Whittaker LA, Kaminsky D, Irvin C (2004). Respiratory System in Extreme Environments. Pulmonary and Critical Care Update (17, Lesson 23).