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Monika Fleckenstein
( out of 595 reviews )

Monika Fleckenstein, MD

Languages spoken: English

Clinical Locations

Primary Location

Midvalley Health Center

Moran Eye Center
243 East 6100 South
Murray , UT 84107

Monika Fleckenstein, MD, specializes in the management and medical treatment of retinal diseases, with a special emphasis on age-related macular degeneration (AMD).

Learn more about Dr. Fleckenstein's clinical practice here.

Dr. Fleckenstein joined the John A. Moran Eye Center in 2019 as a Professor of Ophthalmology and Visual Sciences, with clinical and research appointments. After earning her medical degree at the University of Heidelberg, Germany, Dr. Fleckenstein honed her skills as a research fellow at the Wilmer Eye Institute at Johns Hopkins University and later completed her ophthalmology residency at the University of Bonn, Germany.

Research
Dr. Fleckenstein's primary research interest centers around degenerative retinal diseases, with a focus on AMD. She specializes in applying advanced high-resolution imaging technology to characterize AMD subtypes, identifying prognostic biomarkers for disease progression, and validating clinical endpoints for interventional trials. These efforts have yielded a substantial body of work, including over 100 peer-reviewed publications and 25 book chapters.

In addition to her research contributions, Dr. Fleckenstein plays a vital role as a scientific reviewer for esteemed ophthalmology journals and serves on grant review committees for prestigious organizations such as the National Institutes of Health (NIH) and the German Research Foundation.

Dr. Fleckenstein served as the head of the University of Bonn Department of Ophthalmology Clinical Trial Center from 2013 to 2019. At present, Dr. Fleckenstein is actively contributing her expertise to translational research initiatives at the Moran Eye Center's Sharon Eccles Steele Center for Translational Medicine (SCTM). She serves as the principal investigator/multi-principal investigator for two separate NIH grants, each dedicated to clinically characterizing distinct AMD subtypes: "The Impact of Non-Exudative Type 1 Macular Neovascularization on AMD Progression" (R01EY033365) and "Progression of Early Atrophic Lesions in AMD" (R01EY034965).

Board Certification

Medical Association of North Rhine-Ophthalmology

Patient Rating

4.9 /5
( out of 595 reviews )

The patient rating score is an average of all responses on our patient experience survey. The rating averages scores for all questions about care from our providers.

The scale on which responses are measured is 1 to 5 with 5 being the best score.

Patient Comments

Patient comments are gathered from our patient experience survey and displayed in their entirety. For the convenience of our visitors, some patient comments have been translated from their original language into English while preserving their original meaning as accurately as possible. Patients are de-identified for confidentiality and patient privacy.

MORAN EYE CENTER

She did a very thorough exam and was very honest with me about outcome of treatment.

MIDVALLEY

She is the greatest! Highly recommend her!! Thank you!

MIDVALLEY

very professional

MIDVALLEY

Dr. Fleckenstein was superb - in all ways - information about the disease I have, superb in her connection with me as a patient, and effective in follow up. Thank You!

MIDVALLEY

Dr. Monica Fleckenstein is very knowledgeable, kind, understanding, thorough and genuinely interested in the patient.

MIDVALLEY

Friendly, caring, knowledgeable and an expert!

MIDVALLEY

Awesome!

MIDVALLEY

She is kind and caring and treats the patient wonderfully.

MORAN EYE CENTER

profession, kind and caring and funny

Monika Fleckenstein, MD, specializes in the management and medical treatment of retinal diseases, with a special emphasis on age-related macular degeneration (AMD).

Learn more about Dr. Fleckenstein's clinical practice here.

Dr. Fleckenstein joined the John A. Moran Eye Center in 2019 as a Professor of Ophthalmology and Visual Sciences, with clinical and research appointments. After earning her medical degree at the University of Heidelberg, Germany, Dr. Fleckenstein honed her skills as a research fellow at the Wilmer Eye Institute at Johns Hopkins University and later completed her ophthalmology residency at the University of Bonn, Germany.

Research
Dr. Fleckenstein's primary research interest centers around degenerative retinal diseases, with a focus on AMD. She specializes in applying advanced high-resolution imaging technology to characterize AMD subtypes, identifying prognostic biomarkers for disease progression, and validating clinical endpoints for interventional trials. These efforts have yielded a substantial body of work, including over 100 peer-reviewed publications and 25 book chapters.

In addition to her research contributions, Dr. Fleckenstein plays a vital role as a scientific reviewer for esteemed ophthalmology journals and serves on grant review committees for prestigious organizations such as the National Institutes of Health (NIH) and the German Research Foundation.

Dr. Fleckenstein served as the head of the University of Bonn Department of Ophthalmology Clinical Trial Center from 2013 to 2019. At present, Dr. Fleckenstein is actively contributing her expertise to translational research initiatives at the Moran Eye Center's Sharon Eccles Steele Center for Translational Medicine (SCTM). She serves as the principal investigator/multi-principal investigator for two separate NIH grants, each dedicated to clinically characterizing distinct AMD subtypes: "The Impact of Non-Exudative Type 1 Macular Neovascularization on AMD Progression" (R01EY033365) and "Progression of Early Atrophic Lesions in AMD" (R01EY034965).

Board Certification and Academic Information

Academic Departments Ophthalmology & Visual Sciences -Professor
Board Certification
Medical Association of North Rhine-Ophthalmology

Education history

Professional Medical Medicine - University of Heidelberg School of Medicine M.D.
Doctoral Training Experimental Anesthesiology - University of Freiburg Dr. med.
Research Fellow Inherited Retinal Diseases - Johns Hopkins University Research Fellow
Professional Medical Ophthalmology - University of Bonn Dr. med. habil

Selected Publications

Journal Article

  1. Pfau M, von der Emde L, Dysli C, Möller PT, Thiele S, Lindner M, Schmid M, Rubin DL, Fleckenstein M, Holz FG, Schmitz-Valckenberg (2020). Determinants of Cone and Rod Functions in Geographic Atrophy: AI-Based Structure-Function Correlation. American journal of ophthalmology, 217, 162-173.
  2. Pfau M, Lindner M, Steinberg JS, Thiele S, Brinkmann CK, Fleckenstein M, Holz FG, Schmitz-Valckenberg (2018). Visual field indices and patterns of visual field deficits in mesopic and dark-adapted two-colour fundus-controlled perimetry in macular diseases. The British journal of ophthalmology, 102(8), 1054-1059.
  3. Thiele S, Nadal J, Pfau M, Saßmannshausen M, Fleckenstein M, Holz FG, Schmid M, Schmitz-Valckenberg (2020). Prognostic value of intermediate age-related macular degeneration phenotypes for geographic atrophy progression. The British journal of ophthalmology,
  4. Eter N, Pauleikhoff D, Agostini H, Fleckenstein M, Ziemssen (2020). [Value and formats of quality assurance : Ophthalmology and intravitreal therapy between reality and wishful thinking]. Der Ophthalmologe, 117(4), 298-306.
  5. Böhringer D, Goos D, Ach T, Feltgen N, Fleckenstein M, Kohnen T, Lorenz K, Pielen A, Spital G, Wilhelm B, Böhringer S, Reinhard T, Arbeitsgemeinschaft DOG ¿ Klinische Studienzentren (2019). [Work sampling in ophthalmological clinical studies. A multicenter field study]. Der Ophthalmologe, 116(9), 872-878.
  6. Pfau M, Walther G, von der Emde L, Berens P, Faes L, Fleckenstein M, Heeren TFC, Kortüm K, Künzel SH, Müller PL, Maloca PM, Waldstein SM, Wintergerst MWM, Schmitz-Valckenberg S, Finger RP, Holz F (2020). [Artificial intelligence in ophthalmology : Guidelines for physicians for the critical evaluation of studies]. Der Ophthalmologe, 117(10), 973-988.
  7. Pfau M, Lindner M, Gliem M, Steinberg JS, Thiele S, Finger RP, Fleckenstein M, Holz FG, Schmitz-Valckenberg (2018). Mesopic and dark-adapted two-color fundus-controlled perimetry in patients with cuticular, reticular, and soft drusen. Eye (London, England), 32(12), 1819-1830.
  8. Lindner M, Nadal J, Mauschitz MM, Luning A, Czauderna J, Pfau M, Schmitz-Valckenberg S, Holz FG, Schmid M, Fleckenstein (2017). Combined Fundus Autofluorescence and Near Infrared Reflectance as Prognostic Biomarkers for Visual Acuity in Foveal-Sparing Geographic Atrophy. Investigative ophthalmology & visual science, 58(6), BIO61-BIO67.
  9. Pfau M, Goerdt L, Schmitz-Valckenberg S, Mauschitz MM, Mishra DK, Holz FG, Lindner M, Fleckenstein (2017). Green-Light Autofluorescence Versus Combined Blue-Light Autofluorescence and Near-Infrared Reflectance Imaging in Geographic Atrophy Secondary to Age-Related Macular Degeneration. Investigative ophthalmology & visual science, 58(6), BIO121-BIO130.
  10. Oishi M, Oishi A, Lindner M, Pfau M, Schmitz-Valckenberg S, Holz FG, Fleckenstein (2017). Structural Changes in Optical Coherence Tomography Underlying Spots of Increased Autofluorescence in the Perilesional Zone of Geographic Atrophy. Investigative ophthalmology & visual science, 58(7), 3303-3310.
  11. Pfau M, Lindner M, Muller PL, Birtel J, Finger RP, Harmening WM, Fleckenstein M, Holz FG, Schmitz-Valckenberg (2017). Effective Dynamic Range and Retest Reliability of Dark-Adapted Two-Color Fundus-Controlled Perimetry in Patients With Macular Diseases. Investigative ophthalmology & visual science, 58(6), BIO158-BIO167.
  12. Thiele S, Pfau M, Larsen PP, Fleckenstein M, Holz FG, Schmitz-Valckenberg (2018). Multimodal Imaging Patterns for Development of Central Atrophy Secondary to Age-Related Macular Degeneration. Investigative ophthalmology & visual science, 59(4), AMD1-AMD11.
  13. Lindner M, Kosanetzky S, Pfau M, Nadal J, Gordt LA, Schmitz-Valckenberg S, Schmid M, Holz FG, Fleckenstein (2018). Local Progression Kinetics of Geographic Atrophy in Age-Related Macular Degeneration Are Associated With Atrophy Border Morphology. Investigative ophthalmology & visual science, 59(4), AMD12-AMD18.
  14. Sassmannshausen M, Steinberg JS, Fimmers R, Pfau M, Thiele S, Fleckenstein M, Holz FG, Schmitz-Valckenberg (2018). Structure-Function Analysis in Patients With Intermediate Age-Related Macular Degeneration. Investigative ophthalmology & visual science, 59(3), 1599-1608.
  15. Müller PL, Pfau M, Möller PT, Nadal J, Schmid M, Lindner M, de Sisternes L, Stöhr H, Weber BHF, Neuhaus C, Herrmann P, Schmitz-Valckenberg S, Holz FG, Fleckenstein (2018). Choroidal Flow Signal in Late-Onset Stargardt Disease and Age-Related Macular Degeneration: An OCT-Angiography Study. Investigative ophthalmology & visual science, 59(4), AMD122-AMD131.
  16. Künzel SH, Möller PT, Lindner M, Goerdt L, Nadal J, Schmid M, Schmitz-Valckenberg S, Holz FG, Fleckenstein M, Pfau (2020). Determinants of Quality of Life in Geographic Atrophy Secondary to Age-Related Macular Degeneration. Investigative ophthalmology & visual science, 61(5), 63.
  17. Pfau M, von der Emde L, Dysli C, Thiele S, Möller PT, Lindner M, Nadal J, Schmid M, Schmitz-Valckenberg S, Holz FG, Fleckenstein (2019). Light Sensitivity Within Areas of Geographic Atrophy Secondary to Age-Related Macular Degeneration. Investigative ophthalmology & visual science, 60(12), 3992-4001.
  18. Bax NM, Valkenburg D, Lambertus S, Klevering BJ, Boon CJF, Holz FG, Cremers FPM, Fleckenstein M, Hoyng CB, Lindner M, Foveal Sparing Atrophy Study Team (FAST) (2019). Foveal Sparing in Central Retinal Dystrophies. Investigative ophthalmology & visual science, 60(10), 3456-3467.
  19. Sassmannshausen M, Pfau M, Thiele S, Fimmers R, Steinberg JS, Fleckenstein M, Holz FG, Schmitz-Valckenberg (2020). Longitudinal Analysis of Structural and Functional Changes in Presence of Reticular Pseudodrusen Associated With Age-Related Macular Degeneration. Investigative ophthalmology & visual science, 61(10), 19.
  20. Fleckenstein M, Thiele S, Pfau M, Schmitz-Valckenberg S, Holz F (2019). [Dry Age-Related Macular Degeneration - Epidemiology and Classification]. Klinische Monatsblatter fur Augenheilkunde, 236(9), 1068-1075.
  21. Guymer RH, Rosenfeld PJ, Curcio CA, Holz FG, Staurenghi G, Freund KB, Schmitz-Valckenberg S, Sparrow J, Spaide RF, Tufail A, Chakravarthy U, Jaffe GJ, Csaky K, Sarraf D, Monés JM, Tadayoni R, Grunwald J, Bottoni F, Liakopoulos S, Pauleikhoff D, Pagliarini S, Chew EY, Viola F, Fleckenstein M, Blodi BA, Lim TH, Chong V, Lutty J, Bird AC, Sadda S (2020). Incomplete Retinal Pigment Epithelial and Outer Retinal Atrophy in Age-Related Macular Degeneration: Classification of Atrophy Meeting Report 4. Ophthalmology, 127(3), 394-409.
  22. Thiele S, Nadal J, Fleckenstein M, Fang PP, Pfau M, Schmid M, Hua R, Holz FG, Schmitz-Valckenberg (2018). Longitudinal Analysis of Drusen Volume in Intermediate Age-Related Macular Degeneration Using Two Spectral-Domain Optical Coherence Tomography Scan Patterns. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 239(2-3), 110-120.
  23. von der Emde L, Thiele S, Pfau M, Nadal J, Meyer J, Möller PT, Schmid M, Fleckenstein M, Holz FG, Schmitz-Valckenberg (2020). Assessment of Exudative Activity of Choroidal Neovascularization in Age-Related Macular Degeneration by OCT Angiography. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 243(2), 120-128.
  24. Müller PL, Pfau M, Schmitz-Valckenberg S, Fleckenstein M, Holz F (2021). Optical Coherence Tomography-Angiography in Geographic Atrophy. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 244(1), 42-50.
  25. Pfau M, Lindner M, Goerdt L, Thiele S, Nadal J, Schmid M, Schmitz-Valckenberg S, Sadda SR, Holz FG, Fleckenstein M, Fundus Autofluorescence in Age-Related Macular Degeneration Study Group (2019). PROGNOSTIC VALUE OF SHAPE-DESCRIPTIVE FACTORS FOR THE PROGRESSION OF GEOGRAPHIC ATROPHY SECONDARY TO AGE-RELATED MACULAR DEGENERATION. Retina (Philadelphia, Pa.), 39(8), 1527-1540.
  26. Pfau M, Jolly JK, Wu Z, Denniss J, Lad EM, Guymer RH, Fleckenstein M, Holz FG, Schmitz-Valckenberg (2020). Fundus-controlled perimetry (microperimetry): Application as outcome measure in clinical trials. Progress in retinal and eye research, 82, 100907.
  27. Schmitz-Valckenberg S, Pfau M, Fleckenstein M, Staurenghi G, Sparrow JR, Bindewald-Wittich A, Spaide RF, Wolf S, Sadda SR, Holz F (2020). Fundus autofluorescence imaging. Progress in retinal and eye research, 81, 100893.
  28. Birtel J, Lindner M, Mishra DK, Müller PL, Hendig D, Herrmann P, Holz FG, Fleckenstein M, Gliem M, Charbel Issa (2019). Retinal imaging including optical coherence tomography angiography for detecting active choroidal neovascularization in pseudoxanthoma elasticum. Clinical & experimental ophthalmology, 47(2), 240-249.
  29. von der Emde L, Pfau M, Dysli C, Thiele S, Möller PT, Lindner M, Schmid M, Fleckenstein M, Holz FG, Schmitz-Valckenberg (2019). Artificial intelligence for morphology-based function prediction in neovascular age-related macular degeneration. Scientific reports, 9(1), 11132.
  30. Steinberg JS, Saßmannshausen M, Pfau M, Fleckenstein M, Finger RP, Holz FG, Schmitz-Valckenberg (2017). Evaluation of Two Systems for Fundus-Controlled Scotopic and Mesopic Perimetry in Eye with Age-Related Macular Degeneration. Translational vision science & technology, 6(4), 7.
  31. von der Emde L, Pfau M, Thiele S, Möller PT, Hassenrik R, Fleckenstein M, Holz FG, Schmitz-Valckenberg (2018). Mesopic and Dark-Adapted Two-Color Fundus-Controlled Perimetry in Choroidal Neovascularization Secondary to Age-Related Macular Degeneration. Translational vision science & technology, 8(1), 7.
  32. Dieck S, Ibarra M, Moghul I, Yeung MW, Pantel JT, Thiele S, Pfau M, Fleckenstein M, Pontikos N, Krawitz P (2020). Factors in Color Fundus Photographs That Can Be Used by Humans to Determine Sex of Individuals. Translational vision science & technology, 9(7), 8.
  33. Grassmann F, Harsch S, Brandl C, Kiel C, Nürnberg P, Toliat MR, Fleckenstein M, Pfau M, Schmitz-Valckenberg S, Holz FG, Chew EY, Swaroop A, Ratnapriya R, Klein ML, Mulyukov Z, Zamiri P, Weber BH (2019). Assessment of Novel Genome-Wide Significant Gene Loci and Lesion Growth in Geographic Atrophy Secondary to Age-Related Macular Degeneration. JAMA ophthalmology,
  34. Pfau M, von der Emde L, de Sisternes L, Hallak JA, Leng T, Schmitz-Valckenberg S, Holz FG, Fleckenstein M, Rubin D (2020). Progression of Photoreceptor Degeneration in Geographic Atrophy Secondary to Age-related Macular Degeneration. JAMA ophthalmology, 138(10), 1026-1034.
  35. Pfau M, Möller PT, Künzel SH, von der Emde L, Lindner M, Thiele S, Dysli C, Nadal J, Schmid M, Schmitz-Valckenberg S, Holz FG, Fleckenstein (2020). Type 1 Choroidal Neovascularization Is Associated with Reduced Localized Progression of Atrophy in Age-Related Macular Degeneration. Ophthalmology. Retina, 4(3), 238-248.
  36. Thiele S, Nadal J, Pfau M, Saßmannshausen M, von der Emde L, Fleckenstein M, Holz FG, Schmid M, Schmitz-Valckenberg S, Molecular Diagnostic of Age-related Macular Degeneration Study Group (2020). Prognostic Value of Retinal Layers in Comparison with Other Risk Factors for Conversion of Intermediate Age-related Macular Degeneration. Ophthalmology. Retina, 4(1), 31-40.
  37. Lindner M, Pfau M, Czauderna J, Goerdt L, Schmitz-Valckenberg S, Holz FG, Fleckenstein (2019). Determinants of Reading Performance in Eyes with Foveal-Sparing Geographic Atrophy. Ophthalmology. Retina, 3(3), 201-210.
  38. Saßmannshausen M, Zhou J, Pfau M, Thiele S, Steinberg J, Fleckenstein M, Holz FG, Schmitz-Valckenberg (2020). Longitudinal Analysis of Retinal Thickness and Retinal Function in Eyes with Large Drusen Secondary to Intermediate Age-Related Macular Degeneration. Ophthalmology. Retina, 5(3), 241-250.
  39. Pfau M, Schmitz-Valckenberg S, Ribeiro R, Safaei R, McKeown A, Fleckenstein M, Holz F (2022). Association of complement C3 inhibitor pegcetacoplan with reduced photoreceptor degeneration beyond areas of geographic atrophy. Scientific reports, 12(1), 17870.
  40. Schmitz-Valckenberg S, Fleckenstein M, Zouache MA, Pfau M, Pappas C, Hageman JL, Agrón E, Malley C, Keenan TDL, Chew EY, Hageman G (2022). Progression of Age-Related Macular Degeneration Among Individuals Homozygous for Risk Alleles on Chromosome 1 (CFH-CFHR5) or Chromosome 10 (ARMS2/HTRA1) or Both. JAMA ophthalmology, 140(3), 252-260.
  41. Pfau M, van Dijk EHC, van Rijssen TJ, Schmitz-Valckenberg S, Holz FG, Fleckenstein M, Boon CJ (2021). Estimation of current and post-treatment retinal function in chronic central serous chorioretinopathy using artificial intelligence. Scientific reports, 11(1), 20446.
  42. Künzel SH, Lindner M, Sassen J, Möller PT, Goerdt L, Schmid M, Schmitz-Valckenberg S, Holz FG, Fleckenstein M, Pfau (2021). Association of Reading Performance in Geographic Atrophy Secondary to Age-Related Macular Degeneration With Visual Function and Structural Biomarkers. JAMA ophthalmology, 139(11), 1191-1199.
  43. Behning C, Fleckenstein M, Pfau M, Adrion C, Goerdt L, Lindner M, Schmitz-Valckenberg S, Holz FG, Schmid (2021). Modeling of atrophy size trajectories: variable transformation, prediction and age-of-onset estimation. BMC medical research methodology, 21(1), 170.
  44. Goerdt L, Sauer L, Vitale AS, Modersitzki NK, Fleckenstein M, Bernstein P (2021). Comparing Fluorescence Lifetime Imaging Ophthalmoscopy in Atrophic Areas of Retinal Diseases. Translational vision science & technology, 10(7), 11.
  45. Huss MB, Schmitz-Valckenberg S, Finger RP, Löffler KU, Fleckenstein M, Holz FG, Pfau (2021). The Willingness of Patients to Participate in an Eye Donation Registry for Research. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde, 244(3), 179-186.
  46. Pfau M, Sahu S, Rupnow RA, Romond K, Millet D, Holz FG, Schmitz-Valckenberg S, Fleckenstein M, Lim JI, de Sisternes L, Leng T, Rubin DL, Hallak J (2021). Probabilistic Forecasting of Anti-VEGF Treatment Frequency in Neovascular Age-Related Macular Degeneration. Translational vision science & technology, 10(7), 30.
  47. Sadda SR, Guymer R, Holz FG, Schmitz-Valckenberg S, Curcio CA, Bird AC, Blodi BA, Bottoni F, Chakravarthy U, Chew EY, Csaky K, Danis RP, Fleckenstein M, Freund KB, Grunwald J, Hoyng CB, Jaffe GJ, Liakopoulos S, Monés JM, Pauleikhoff D, Rosenfeld PJ, Sarraf D, Spaide RF, Tadayoni R, Tufail A, Wolf S, Staurenghi (2018). Consensus Definition for Atrophy Associated with Age-Related Macular Degeneration on OCT: Classification of Atrophy Report 3. Ophthalmology, 125(4), 537-548.
  48. Ribeiro L, Bandello F, Tejerina AN, Vujosevic S, Varano M, Egan C, Sivaprasad S, Menon G, Massin P, Verbraak FD, Lund-Andersen H, Martinez JP, Jürgens I, Smets E, Coriat C, Wiedemann P, Ágoas V, Querques G, Holz FG, Nunes S, Neves C, Cunha-Vaz J, Evicr Net Study Grou (2015). Collaborator: Characterization of Retinal Disease Progression in a 1-Year Longitudinal Study of Eyes With Mild Nonproliferative Retinopathy in Diabetes Type 2. . Investigative ophthalmology & visual science, 56(9), 5698-705.
  49. Cheng Y, Fleckenstein M, Schmitz-Valckenberg MS, Lu J, Liu Z, Herrera G, Gregori G, Wang RK, Rosenfeld PJ, Trivizki (2025). Comparison Between Optical Coherence Tomography B-scan and En Face Imaging for the Diagnosis of Early Macular Atrophy in Age-Related Macular Degeneration. American journal of ophthalmology, 270, 252-260.
  50. Wu Z, Pfau M, Fleckenstein M, Guymer R (2024). Microperimetry Characteristics of Regions With a Truly Nonresponding Location: Implications for Atrophic Age-Related Macular Degeneration. Investigative ophthalmology & visual science, 65(8), 44.
  51. von der Emde L, Rennen GC, Vaisband M, Hasenauer J, Liegl R, Fleckenstein M, Pfau M, Holz FG, Ach (2024). Impact of lens autofluorescence and opacification on retinal imaging. BMJ open ophthalmology, 9(1),
  52. von der Emde L, Rennen GC, Vaisband M, Hasenauer J, Liegl R, Fleckenstein M, Pfau M, Holz FG, Ach (2024). Personalized Lens Correction Improves Quantitative Fundus Autofluorescence Analysis. Investigative ophthalmology & visual science, 65(3), 13.
  53. Künzel SH, Broadbent E, Möller PT, Lindner M, Goerdt L, Czauderna J, Schmitz-Valckenberg S, Holz FG, Pfau M, Fleckenstein (2024). Association of Lesion Location and Functional Parameters with Vision-Related Quality of Life in Geographic Atrophy Secondary to Age-related Macular Degeneration. Ophthalmology. Retina, 8(8), 794-803.
  54. Künzel SH, Broadbent E, Möller PT, Lindner M, Goerdt L, Czauderna J, Schmitz-Valckenberg S, Holz FG, Pfau M, Fleckenstein (2023). Impact of lesion location and functional parameters on vision-related quality of life in geographic atrophy secondary to AMD.

Review

  1. Fleckenstein M, Mitchell P, Freund KB, Sadda S, Holz FG, Brittain C, Henry EC, Ferrara (2018). The Progression of Geographic Atrophy Secondary to Age-Related Macular Degeneration. Ophthalmology, 125(3), 369-390.
  2. Fleckenstein M, Keenan TDL, Guymer RH, Chakravarthy U, Schmitz-Valckenberg S, Klaver CC, Wong WT, Chew E (2021). Age-related macular degeneration. Nature reviews. Disease primers, 7(1), 31.
  3. von der Emde L, Pfau M, Holz FG, Fleckenstein M, Kortuem K, Keane PA, Rubin DL, Schmitz-Valckenberg (2021). AI-based structure-function correlation in age-related macular degeneration. Eye (London, England), 35(8), 2110-2118.
  4. Schmitz-Valckenberg S, Pfau M, Fleckenstein M, Staurenghi G, Sparrow JR, Bindewald-Wittich A, Spaide RF, Wolf S, Sadda SR, Holz F (2021). Fundus autofluorescence imaging. Progress in retinal and eye research, 81, 100893.
  5. Pfau M, Jolly JK, Wu Z, Denniss J, Lad EM, Guymer RH, Fleckenstein M, Holz FG, Schmitz-Valckenberg (2021). Fundus-controlled perimetry (microperimetry): Application as outcome measure in clinical trials. Progress in retinal and eye research, 82, 100907.
  6. Broadbent E, Künzel SH, Pfau M, Schmitz-Valckenberg S, Fleckenstein (2025). Age-related macular degeneration: natural history revisited in geographic atrophy. Eye (London, England), 39(2), 217-227.
  7. Lad EM, Fleckenstein M, Holz FG, Shen L, Priore LVD, Silva R, Staurenghi G, Waheed N, Chakravarthy (2024). Informing Endpoints for Clinical Trials of Geographic Atrophy. Annual review of vision science, 10(1), 455-476.
  8. Chang P, von der Emde L, Pfau M, Künzel S, Fleckenstein M, Schmitz-Valckenberg S, Holz F (2024). [Use of artificial intelligence in geographic atrophy in age-related macular degeneration]. Die Ophthalmologie, 121(8), 616-622.
  9. Fleckenstein M, Schmitz-Valckenberg S, Chakravarthy (2024). Age-Related Macular Degeneration: A Review. JAMA, 331(2), 147-157.
  10. Pfau M, Künzel SH, Pfau K, Schmitz-Valckenberg S, Fleckenstein M, Holz F (2023). Multimodal imaging and deep learning in geographic atrophy secondary to age-related macular degeneration. Acta ophthalmologica, 101(8), 881-890.

Conference Proceedings

  1. Holz FG, Sadda SR, Staurenghi G, Lindner M, Bird AC, Blodi BA, Bottoni F, Chakravarthy U, Chew EY, Csaky K, Curcio CA, Danis R, Fleckenstein M, Freund KB, Grunwald J, Guymer R, Hoyng CB, Jaffe GJ, Liakopoulos S, Mones JM, Oishi A, Pauleikhoff D, Rosenfeld PJ, Sarraf D, Spaide RF, Tadayoni R, Tufail A, Wolf S, Schmitz-Valckenberg (2017). Imaging Protocols in Clinical Studies in Advanced Age-Related Macular Degeneration: Recommendations from Classification of Atrophy Consensus Meetings. Ophthalmology, 124(4), 464-478.
  2. Sadda SR, Guymer R, Holz FG, Schmitz-Valckenberg S, Curcio CA, Bird AC, Blodi BA, Bottoni F, Chakravarthy U, Chew EY, Csaky K, Danis RP, Fleckenstein M, Freund KB, Grunwald J, Hoyng CB, Jaffe GJ, Liakopoulos S, Monés JM, Pauleikhoff D, Rosenfeld PJ, Sarraf D, Spaide RF, Tadayoni R, Tufail A, Wolf S, Staurenghi (2018). Consensus Definition for Atrophy Associated with Age-Related Macular Degeneration on OCT: Classification of Atrophy Report 3. Ophthalmology, 125(4), 537-548.

Editorial

  1. Fleckenstein (2025). Insights into Alcohol and Age-related Macular Degeneration Progression. Ophthalmology. Retina, 9(3), 197-199.