Ryan A. Metcalf
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Ryan A. Metcalf, MD, CQA

Languages spoken: English

  • Dr. Metcalf is Section Chief of Transfusion Medicine, Medical Director of the Transfusion Service, Associate Professor of Pathology, and Inpatient Chief Value Officer for the Department of Pathology at the University of Utah Health and ARUP Laboratories. He completed a residency in Anatomic and Clinical Pathology and a fellowship in Transfusion Medicine at Stanford University and is board certified in these disciplines. He also has expertise in quality management and is a Certified Quality Auditor.

    Dr. Metcalf practices transfusion medicine and his specific interests include data-driven/informatics approaches to patient blood management, quality management, and innovation. He was previously Assistant Professor at the University of Washington where he helped build a new FDA-registered hospital-based transfusion service laboratory. He was recruited to the University of Utah and ARUP Laboratories in 2017. His research interests include the use of advanced data visualization to improve understanding of patient blood management (PBM) clinical practice quality, safe and effective use of artificial intelligence in healthcare, evidence-based clinical decision making, and data-driven approaches to improve our understanding of risks associated with blood transfusion. He is co-inventor of a novel advanced data visualization tool that evaluates PBM practice.

    Dr. Metcalf is Chair of the Association for the Advancement of Blood and Biotherapies (AABB) Clinical Transfusion Medicine Committee, a member of the AABB Patient Blood Management Standards Committee, and a member of the College of American Pathologists (CAP) Transfusion, Apheresis, and Cellular Therapy Committee. He is active in Transfusion Medicine education and received the department's Outstanding Teaching Award for Clinical Pathology faculty in 2020. He also received the Department's Bill Roberts Award for Excellence in Laboratory Medicine in 2023.

    Specialties

    Board Certification

    American Board of Pathology (Anatomic & Clinical)
    American Board of Pathology (Sub: Blood Banking/Transfusion Medicine)
    National Board of Medical Examiners

  • Dr. Metcalf is Section Chief of Transfusion Medicine, Medical Director of the Transfusion Service, Associate Professor of Pathology, and Inpatient Chief Value Officer for the Department of Pathology at the University of Utah Health and ARUP Laboratories. He completed a residency in Anatomic and Clinical Pathology and a fellowship in Transfusion Medicine at Stanford University and is board certified in these disciplines. He also has expertise in quality management and is a Certified Quality Auditor.

    Dr. Metcalf practices transfusion medicine and his specific interests include data-driven/informatics approaches to patient blood management, quality management, and innovation. He was previously Assistant Professor at the University of Washington where he helped build a new FDA-registered hospital-based transfusion service laboratory. He was recruited to the University of Utah and ARUP Laboratories in 2017. His research interests include the use of advanced data visualization to improve understanding of patient blood management (PBM) clinical practice quality, safe and effective use of artificial intelligence in healthcare, evidence-based clinical decision making, and data-driven approaches to improve our understanding of risks associated with blood transfusion. He is co-inventor of a novel advanced data visualization tool that evaluates PBM practice.

    Dr. Metcalf is Chair of the Association for the Advancement of Blood and Biotherapies (AABB) Clinical Transfusion Medicine Committee, a member of the AABB Patient Blood Management Standards Committee, and a member of the College of American Pathologists (CAP) Transfusion, Apheresis, and Cellular Therapy Committee. He is active in Transfusion Medicine education and received the department's Outstanding Teaching Award for Clinical Pathology faculty in 2020. He also received the Department's Bill Roberts Award for Excellence in Laboratory Medicine in 2023.

    Board Certification and Academic Information

    Academic Departments Pathology -Associate Professor (Clinical)
    Board Certification
    American Board of Pathology (Anatomic & Clinical)
    American Board of Pathology (Sub: Blood Banking/Transfusion Medicine)
    National Board of Medical Examiners

    Education history

    Fellowship Transfusion Medicine - Stanford University School of Medicine Fellow
    Residency Anatomic and Clinical Pathology - Stanford University School of Medicine Resident
    Fellowship Pathology - Stanford University School of Medicine Predoctoral Fellow
    Professional Medical Medicine - University of California, Davis School of Medicine M.D.
    Undergraduate Cell and Developmental Biology - University of California, Santa Barbara B.S.

    Selected Publications

    Journal Article

    1. Jug R, La Rocca U, Al-Riyami AZ, Bathla A, Metcalf RA, White SK, Stanworth SJ, Nahirniak S (2025). The clinical use of platelet transfusions: A systematic literature review and meta-analysis. Transfusion.
    2. Metcalf RA, Nahirniak S, Guyatt G, Bathla A, White SK, Al-Riyami AZ, Jug RC, La Rocca U, Callum JL, Cohn CS, DeAnda A, DeSimone RA, Dubon A, Estcourt LJ, Filipescu DC, Fung MK, Goel R, Hess AS, Hume HA, Kaufman RM, Kranke P, Louw VJ, Moller MH, Murphy MF, Muszynski JA, OKelly CJ, Pagano MB, Patidar GK, Pavenski K, Poston JN, Saifee NH, Stolla M, Szczepiorkowski ZM, Tobian AAR, Uberoi R, Water J, Williams B, Wood EM, Zantek ND, Zeller MP, Grossman BJ, Stanworth SJ (2025). Platelet Transfusion: 2025 AABB and ICTMG International Clinical Practice Guidelines. JAMA.
    3. White SK, Walker BS, Potter S, Anderson D, Metcalf RA (2025). Estimating the incidence of transfusion associated circulatory overload using active surveillance: A systematic review and meta-analysis. Transfusion.
    4. Zhang XY, Murphy M, Collins GP, Louw VJ, Tadzimirwa GY, Arora S, Radhakrishnan N, Gonzalez C, Metcalf RA, Swenson EA, Nuez MA, Saa E, Al-Riyami AZ, Tabatabaey A, Lin Y, Tedjaseputra A, Wood EM, Pedraza A, Sanz C, Streel C, Deneys V, Bravo AG, Maldonado K, Amorim L, Ferraz T, Tani Y, Goto N, Delettre F, Tiberghien P, Zwaginga JJ, Foukaneli T, Kerr P, Mutindu SM, Nganzele AM, Schfer R, Dunbar N (2025). Worldwide Variability in the Use of Irradiated Blood in Patients with Haematological Malignancy – a Vox Sanguinis International Forum. Vox Sang.
    5. Yarava A, Marshall C, Reichert D, Ye A, Khanal P, Robbins S, Sachais B, Oh D, Metcalf RA, Cantilena K, King K, Reyes M, Adamski J, Marques M, Tran MH, Allen E, Pach D, Blumberg N, Hobbs R, Nash T, Shenoy AG, Mosniam GS, Fukuta Y, Patel B, Heath SL, Levine AC, Meisenberg BR, Spivak ES, Anjan S, Huaman MA, Blair JE, Currier JS, Paxton JH, Rausch W, Oei K, Abinante M, Hammit LL, Sutcliffe CG, Forthal DN, Zand MS, Kassaye SG, Cachay ER, Gebo KA, Shoham S, Casadevall A, McBee NA, Amirault D, Wang Y, Hopkins E, Shade DM, Layendecker O, Klein SL, Park HS, Lee J, Caturegli P, Raval JS, Cruser D, Ziman A, Gerber J, Gniadek TJ, Bloch EM, Tobian AR, Hanley DF, Sullivan DJ, Lane K, CSSC Group (2024). Creating a plasma coordination center to support COVID-19 outpatient trials across a national network of hospital blood banks. J Clin Transl Sci.
    6. Poston JN, Andrews J, Arya S, Chou ST, Cohn CS, Covington M, Crowe EP, Goel R, Gupta GK, Haspel RL, Hess AS, Ipe TS, Jacobson J, Khan J, Murphy M, OBrien K, Pagano MB, Panigrahi AK, Salazar E, Saifee NH, Stolla M, Zantek ND, Ziman A, Metcalf RA (2024). Current Advances in 2023: A critical review of selected topics by the Association for the Advancement of Blood and Biotherapies (AABB) Clinical Transfusion Medicine Committee. Transfusion.
    7. Metcalf RA, Lin H, Wilburn J, Lex A (2024). An innovative data visualization tool for patient blood management. Transfusion.
    8. Walker BS, White SK, Metcalf RA (2024). Bacterial Culture of Platelets with Large Volume Delayed Sampling. Ann Blood.
    9. Pagano MB, Stanworth SJ, Valentine S, Metcalf RA, Wood EM, Pavenski K, Cholette J, So-Osman C, Carson JL (2024). The 2023 AABB International Guidelines for Red Blood Cell Transfusions: What Is New? Transfusion.
    10. White SK, Walker BS, Schmidt RL, Metcalf RA (2023). The incidence of transfusion related acute lung injury using active surveillance: A systematic review and meta-analysis. Transfusion.
    11. Carson JL, Stanworth SJ, Guyatt G, Valentine S, Bakhtary S, Cohn CS, Dubon A, Grossman BJ, Gupta GK, Hess AS, Jacobson JL, Kaplan LJ, Lin Y, Metcalf RA, Murphy CH, Pavenski K, Prochaska MT, Raval JS, Salazar E, Saifee NH, Tobian AAR, So-Osman C, Waters J, Wood EM, Zantek ND, Dennis J, Pagano MB (2023). Red Blood Cell Transfusion 2023 Clinical Practice Guidelines. JAMA, 330(19), 1892-1902.
    12. Li N, Pham T, Cheng C, McElfresh DC, Metcalf RA, Russell WA, Birch R, Yurkovich JT, Montemayor-Garcia C, Lane WJ, Tobian AAR, Roubinian N, Seheult J, Goel R (2023). Blood Demand Forecasting and Supply Management: An Analytical Assessment of Key Studies Utilizing Novel Computational Techniques. Transfus Med Rev, 37(4), 150768-150768.
    13. Walker BS, Schmidt RL, White SK, Metcalf RA (2023). Meta-analysis of bacterial growth characteristics in platelet components: refining the inputs of a simulation analysis comparing the relative safety of testing strategies. Transfusion, 63(9), 1719-1727.
    14. Metcalf RA, Cohn CS, Bakhtary S, Gniadek T, Gupta G, Harm S, Haspel R, Hess AS, Jacobson J, Lokhandwala PM, Murphy C, Poston JN, Prochaska MT, Raval JS, Saifee NH, Salazar E, Shan H, Zantek ND, Pagano MB (2023). Current advances in 2022: A critical review of selected topics by the Association for the Advancement of Blood and Biotherapies (AABB) Clinical Transfusion Medicine Committee. Transfusion, 63(8), 1590-1600.
    15. Karafin MS, DeSimone RA, Dvorak J, Metcalf RA, Pagano MB, Park YA, Schwartz J, Souers RJ, Szczepiorkowski ZM, Uhl L, Ramsey G (2023). Antibody Titers in Transfusion Medicine: A Critical Reevaluation of Testing Accuracy, Reliability, and Clinical Use. Arch Pathol Lab Med, 147(12), 1351-1359.
    16. Walker BS, Schmidt RL, Moore RA, White SK, Fisher MA, Metcalf RA (2023). Bacterial culture time to detection in platelet components: an evidence synthesis and estimation of detection failures. Transfusion, 63(1), 182-192.
    17. White SK, Schmidt RL, Walker BS, Metcalf RA (2023). The Epidemiology of Transfusion-Related Acute Lung Injury (TRALI): A Scoping Review and Analysis. Transfusion, 63(1), 104-116.
    18. Potter S, Sudarshan D, Lazar-Molnar E, Baker S, Metcalf RA, Lin L (2022). Life Threatening Platelet Transfusion Refractoriness Due to an Anamnestic Human Leukocyte Antigen Alloantibody Response. Transfusion, 62(11), 2161-2162.
    19. Estcourt LJ, Cohn CS, Pagano MB, Iannizzi C, Kreuzberger N, Skeet N, Allen ES, Bloch EM, Beaudoin G, Casadevall A, Devine DV, Foroutan F, Gniadek TJ, Goes R, Gorlin J, Grossman BJ, Joyner MJ, Metcalf RA, Raval JS, Rice TW, Shaz BH, Vassallo RR, Winters JL, Tobian AAR (2022). Clinical Practice Guidelines from the Association for the Advancement of Blood and Biotherapies (AABB): COVID-19 Convalescent Plasma. Ann Intern Med, 175(9), 1310.
    20. Metcalf RA, Cohn CS, Allen ES, Bakhtary S, Gniadek T, Gupta G, Harm S, Haspel R, Hess A, Jacobson J, Lokhandwala P, Murphy C, Poston J, Prochaska MT, Raval JS, Saifee NH, Salazar E, Shan H, Zantek N, Pagano MB (2022). Current advances in transfusion medicine 2021: A critical review of selected topics by the Association for the Advancement for Blood and Biotherapies (AABB) Clinical Transfusion Medicine Committee. Transfusion, 62(7), 1435-1445.
    21. Evan M Bloch, Aaron AR Tobian, Shmuel Shoham, Daniel F Hanley, Thomas J Gniadek, Edward R Cachay, Barry R Meisenberg, Kimberly Kafka, Christi Marshall, Sonya L Heath, Aarthi Shenoy, James H Paxton, Adam Levine, Donald Forthal, Yuriko Fukuta, Moises A Huaman, Alyssa Ziman, Jill Adamski, Jonathan Gerber, Daniel Cruser, Seble G Kassaye, Giselle S Mosnaim, Bela Patel, Ryan A Metcalf, Shweta Anjan, Ronald B Reisler, Anusha Yarava, Karen Lane, Nichol McBee, Amy Gawad, Jay S Raval, Martin Zand, Matthew Abinante, Patrick B Broderick, Arturo Casadevall, David Sullivan, Kelly A Gebo (2022). How do I implement an outpatient program for the administration of convalescent plasma for COVID-19? Transfusion, 62(5), 933-941.
    22. Wang Z, Zhe S, Zimmerman J, Morrissey C, Tonna JE, Sharma V, Metcalf RA (2022). Development and Validation of a Machine Learning Method to Predict Intraoperative Red Blood Cell Transfusions in Cardiothoracic Surgery. Sci Rep, 12(1), 1355-1355.
    23. Korley FK, Durkalski-Mauldin V, Yeatts SD, Schulman K, Davenport RD, Dumont LJ, El Kassar N, Foster LD, Hah JM, Jaiswal S, Kaplan A, Lowell E, McDyer JF, Quinn J, Triulzi DJ, Van Huysen C, Stevenson VLW, Yadav K, Jones CW, Kea B, Burnett A, Reynolds JC, Greineder CF, Haas NL, Beiser DG, Silbergleit R, Barsan W, Callaway CW SIREN-C3PO Investigators (2021). Early convalescent plasma for high-risk outpatients with COVID-19. . N Engl J Med, 385(21), 1951-1960.
    24. K Fennell, MA Keller, MA Villa, C Paccapelo, M Kucerakova, J Rosochova, C Clemente Dossantos, L Brackney, CJ Lee, R Metcalf, G Crovetti, M Barbieri, S Travali, G Barrotta, G Giuca, L Guerra, G Ochoa-Garay (2021). New ABO intron 1 variant alleles. Immunohematology, 37(4), 178-184.
    25. Benson AD, Metcalf RA, Cail K, Rollins MD, Warrick CM, Falkner D, Clark EAS, Nelson RA, Einerson BD (2021). Transfusion Preparedness on Labor and Delivery: An Initiative to Improve Safety and Cost. Obstet Gynecol, 138(5), 788-794.
    26. Allen ES, Cohn CS, Bakhtary S, Dunbar NM, Gniadek T, Hopkins CK, Jacobsen J, Lokhandwala PM, Metcalf RA, Murphy C, Prochaska MT, Raval JS, Shan H, Storch EK, Pagano MB (2021). Current advances in Transfusion Medicine 2020: A critical review of selected topics by the Association for the Advancement for Blood and Biotherapies (AABB) Clinical Transfusion Medicine Committee. Transfusion, 61(9), 2756-2767.
    27. Lin H, Metcalf RA, Wilburn J, Lex A co-first authors (2021). Sanguine: Visual Analysis for Patient Blood Management. Inf Vis, 20(2-3), 123-137.
    28. Corean J, White SK, Schmidt RL, Walker BS, Fisher M, Metcalf RA (2021). Platelet Component False Positive Detection Rate in Aerobic and Anaerobic Primary Culture: A Systematic Review and Meta-Analysis. Transfus Med Rev, 35(3), 44-52.
    29. Moore RA, Schmidt RL, Metcalf RA (2021). In reply: Window periods for secondary bacterial culture of platelets according to FDA Guidance. Transfusion, 61(4), 1343-1344.
    30. Karafin MS, Becker JL, Berg M, DeSimone R, Draper N, Hudgins J, Metcalf RA, Pagano MB, Park YA, Rossmann SN, Schwartz J, Souers R, Thomas L, Uhl L, Ramsey GE (2021). Heterogeneity in approaches for switching from universal to patient ABO type-specific blood components during massive hemorrhage: An international survey and review of the literature. Arch Pathol Lab Med, 145(12), 1499-1504.
    31. Self WH, Stewart TG, Wheeler AP, Atrouni WE, Bistran-Hall AJ, Casey JD, Cataldo VD, Chappell JD, Cohn CS, Collins JB, Denison MR, de Wit M, Dixon SL, Duggal A, Edwards TL, Fontaine MJ, Ginde AA, Harkins MS, Harrington T, Harris ES, Hoda D, Ipe TS, Jaiswal SJ, Johnson NJ, Jones AE, Laguio-Vila M, Lindsell CJ, Mallada J, Mammen MJ, Metcalf RA, Middleton EA, Mucha S, ONeal HR, Pannu SR, Pulley JM, Qiao X, Raval JS, Rhoads JP, Schrager H, Shanholtz C, Shapiro NI, Schrantz SJ, Thomsen I, Vermillion KK, Bernard GR, Rice TW (2021). Passive Immunity Trial for Our Nation (PassITON): study protocol for a randomized placebo-control clinical trial evaluating COVID-19 convalescent plasma in hospitalized adults. Trials, 22(1), 221-221.
    32. Silva O, Charu V, Ewalt MD, Metcalf RA, Zhao S, Castellanos EM, Orellana E, Natkunam Y, Luna-Fineman S (2021). Classic Hodgkin Lymphoma in Guatemalan Children of Age Less than Six Years: Analysis of Immune Regulatory Pathways and the Tumor Microenvironment. Leuk Lymphoma, 62(7), 1609-1618.
    33. Cohn CS, Estcourt L, Grossman BJ, Pagano MB, Allen ES, Bloch E, Casadevall A, Devine DV, Dunbar NM, Foroutan F, Gniadek TJ, Goel R, Gorlin J, Joyner MJ, Metcalf RA, Raval JS, Rice TW, Shaz BH, Vassallo RR, Winters JL, Beaudoin G, Tobian AAR (2021). COVID-19 convalescent plasma: interim recommendations from the Association for the Advancement for Blood and Biotherapies (AABB). Transfusion, 61(4), 1313-1323.
    34. Metcalf RA, Goodfellow J, Cail K, Blaylock R, Kawamoto K, Enniss T, Galaviz C, Lim M, Reddy S, Sharma V, Wanner N (2021). Electronic clinical decision support: evidence that default settings influence end user behavior. Transfusion, 61(3), 669-670.
    35. Moore RA, Schmidt RL, Metcalf RA (2021). The Impact of the Sample Time of Secondary Bacterial Culture on the Risk of Exposure to Contaminated Platelet Components: A Mathematical Analysis. Transfusion, 31(3), 873-882.
    36. Luetkens T, Metcalf RA, Planelles V, Zheng Y, Larragoite ET, Spivak E, Spivak AM, Steinbach M, Blaylock RC, Avila SV, Hankey K, Martins TB, Slev PR, Mannuel HD, Sajadi M, Rapoport AP, and Atanackovic D (2020). Successful transfer of anti-SARS-CoV-2 immunity using convalescent plasma in a multiple myeloma patient with hypogammaglobulinemia and COVID-19 . Blood Adv, 4(19), 4864-4868.
    37. Corean J, White SK, Schmidt RL, Walker BS, Fisher MA, Metcalf RA (2020). The incremental benefit of anaerobic culture for controlling bacterial risk in platelets: a systematic review and meta-analysis. Vox Sang, 116(4), 397-404.
    38. Walker BS, White SK, Schmidt RL, Metcalf RA (2020). Residual bacterial detection rates following primary culture as determined by secondary culture and rapid testing in platelet components: a systematic review and meta-analysis. Transfusion, 60(9), 2029-2037.
    39. Walker BS, Schmidt RL, Fisher MA, White SK, Blaylock RC, Metcalf RA (2020). The comparative safety of bacterial risk control strategies for platelet components: A simulation study. Transfusion, 60(8), 1723-1731.
    40. Pagano MB, Allen ES, Dunbar NM, Goel R, Harm S, Hopkins CK, Jacobsen J, Lokhandwala PM, Metcalf RA, Raval JS, Schwartz J, Spinella PC, Storch E, Cohn CS (2020). Current Advances in Transfusion Medicine: A 2019 review of selected topics from the Association for the Advancement for Blood and Biotherapies (AABB) Clinical Transfusion Medicine Committee. Transfusion, 60(7), 1614-1623.
    41. White SK, Schmidt RL, Walker BS, Metcalf RA (2020). Bacterial contamination rate of platelet components by primary culture: A systematic review and meta-analysis. Transfusion, 60(5), 986-996.
    42. Lim MY, Pagano MB, Metcalf RA (2020). Things we do for no reason: routinely prescribing transfusion premedication to prevent acute transfusion reactions. J Hosp Med, 15(11), 684-686.
    43. Metcalf RA, White S, Potter S, Barney R, Hunter C, White M, Enniss T, Galaviz C, Reddy S, Wanner N, Schmidt RL, Blaylock R (2019). The association of inpatient blood utilization and diagnosis related group weight: implications for risk-adjusted benchmarking. Transfusion, 59(7), 2316-2323.
    44. Gavva C, Barroso J, Gernsheimer T, Metcalf RA, Warner P, Pagano MB (2019). Response to Random Apheresis Platelets versus HLA-Selected Platelets versus Pooled Platelets in HLA-sensitized Patients. Transfusion, 59(7), 2276-2281.
    45. Pagano MB, Katchatag B, Khoobyari S, Van Gerwen M, Sen N, Haley R, Gernsheimer T, Hess JR, Metcalf RA (2019). Evaluating Safety and Cost-Effectiveness of Platelets Stored in Additive Solution (PAS-F) as a Hemolysis Risk Mitigation Strategy. Transfusion, 59(4), 1246-1251.
    46. Metcalf RA, Calvaresi E, Tonna JE, Blaylock R, Pearson L (2019). Severe Hemolysis Following Extracorporeal Right Ventricular Assist Device Placement. Transfusion, 59(4), 1178-1179.
    47. Murphy C, Parakh R, Metcalf RA, Pagano MB (2018). Transfusion Associated Chest Pain. Transfusion, 59(2), 463-469.
    48. Metcalf RA, Khan J, Andrews J, Mayock D, Billimoria Z, Pagano MB (2018). Severe ABO Hemolytic Disease of the Newborn Requiring Exchange Transfusion. J Pediatr Hematol Oncol, 41(8), 632-634.
    49. Metcalf RA, Pagano MB, Hess JR, Reyes J, Perkins JD, Montenovo MI (2018). A Data-Driven Patient Blood Management Strategy in Liver Transplantation. Vox Sang, 113(5), 421-429.
    50. Corean J, Al-Tigar R, Pysher T, Blaylock R, Metcalf RA (2018). Quality improvement after multiple fatal transfusion-transmitted bacterial infections. Am J Clin Pathol, 149(4), 293-299.
    51. Hess JR, Ramos PJ, Sen NE, Cruz-Cody VG, Tuott EE, Louzon MJ, Bulger EM, Arbabi S, Pagano MB, Metcalf RA (2018). Quality management of a massive transfusion protocol. Transfusion, 58(2), 480-484.
    52. Mays, JA, Greene DN, Metcalf RA, Pagano MB (2018). Transfusion support for transgender men of childbearing age. Transfusion, 58, 823-825.
    53. Pagano MB, Metcalf RA, Hess JR, Reyes J, Perkins JD, Montenovo MI (2018). A high plasma: red blood cell transfusion ratio during liver transplantation is associated with decreased blood utilization. Vox Sang, 113(3), 268-274.
    54. Hess JR, Hayden BK, Cruz-Cody VG, Louzon MJ, Tuott EE, Sen NE, Gary R, Ramos PJ, Daniel-Johnson JA, Metcalf RA, Pagano MB (2017). Building a new transfusion service. Am J Clin Pathol, 148(2), 173-178.
    55. Metcalf RA, Bakhtary S, Goodnough LT, Andrews J (2016). Clinical Pattern in Hypotensive Transfusion Reactions. Anesth Analg, 123(2), 268-73. (Read full article)
    56. Metcalf RA, Baker SA, Goodnough LT, Shah N (2016). Transportation Cooler Interventions Reduce Plasma and RBC Product Wastage. Am J Clin Pathol, 146(1), 18-24. (Read full article)
    57. Hartmann S, Winkelmann R, Metcalf RA, Treetipsatit J, Warnke RA, Natkunam Y, Hansmann ML (2015). Immunoarchitectural patterns of progressive transformation of germinal centers with and without nodular lymphocyte-predominant Hodgkin lymphoma. Hum Pathol, 46(11), 1655-61. (Read full article)
    58. Metcalf RA, Wang L, Deos PH, Chock E, Warnke RA, Natkunam Y (2015). Extracavitary Primary Effusion Lymphoma Presenting in a Lymph Node Without Lymphomatous Effusions. Hum Pathol (N Y), 2(2), 36-41.
    59. Treetipsatit J, Metcalf RA, Warnke RA, Natkunam Y (2015). Large B-cell lymphoma with T-cell-rich background and nodules lacking follicular dendritic cell meshworks: description of an insufficiently recognized variant. Hum Pathol, 46(1), 74-83. (Read full article)
    60. Metcalf RA, Monabati A, Vyas M, Roncador G, Gualco G, Bacchi CE, Younes SF, Natkunam Y, Freud AG (2014). Myeloid cell nuclear differentiation antigen is expressed in a subset of marginal zone lymphomas and is useful in the differential diagnosis with follicular lymphoma. Hum Pathol, 45(8), 1730-6. (Read full article)
    61. Metcalf RA, Bashey S, Wysong A, Kim J, Kim YH, Gratzinger D (2013). Intravascular ALK-negative anaplastic large cell lymphoma with localized cutaneous involvement and an indolent clinical course: toward recognition of a distinct clinicopathologic entity. Am J Surg Pathol, 37(4), 617-23. (Read full article)
    62. Sankaran VG, Ludwig LS, Sicinska E, Xu J, Bauer DE, Eng JC, Patterson HC, Metcalf RA, Natkunam Y, Orkin SH, Sicinski P, Lander ES, Lodish HF (2012). Cyclin D3 coordinates the cell cycle during differentiation to regulate erythrocyte size and number. Genes Dev, 26(18), 2075-87. (Read full article)
    63. Metcalf RA, Zhao S, Anderson MW, Lu ZS, Galperin I, Marinelli RJ, Cherry AM, Lossos IS, Natkunam Y (2010). Characterization of D-cyclin proteins in hematolymphoid neoplasms: lack of specificity of cyclin-D2 and D3 expression in lymphoma subtypes. Mod Pathol, 23(3), 420-33. (Read full article)

    Book Chapter

    1. Santebennur B, Metcalf RA (). Data Analytics. In Eichbaum QG, ed. Global Transfusion Education: Informatics, Biotherapies, Research, and Ethics. AABB: 2025. Bethesda, MD.
    2. Metcalf RA, Cancelas J, Knels R (). Artificial Intelligence and Machine Learning. In Eichbaum QG, ed. Global Transfusion Education: Informatics, Biotherapies, Research, and Ethics. AABB: 2025. Bethesda, MD.

    Abstract

    1. Swenson E, Besse A, Metcalf RA, Baker SA (2024). Expanding the acceptable donor-specific antibody mean fluorescence intensity results in acceptable platelet corrected count increments [Abstract]. (Epub ahead of print)
    2. White SK, Schmidt RL, Walker BS, Metcalf RA (2023). The incidence of reported transfusion related acute lung injury (TRALI): a systematic review and meta-analysis [Abstract].
    3. Metcalf RA, Walker BS, Schmidt RL (2022). The relative safety of platelet testing strategies using a single bacterial culture: policy comparisons based on a discrete threshold model [Abstract].
    4. White SK, Corean J, Schmidt RL, Walker BS, Metcalf RA (2020). The false positive rate associated with testing for bacterial contamination of platelet components: A systematic review and meta-analysis [Abstract].
    5. White SK, Corean J, Schmidt RL, Walker BS, Metcalf RA (2020). The False Positive Rate Associated with Testing For Bacterial Contamination of Platelet Components: A Systematic Review and Meta-Analysis. Poster Presentation. AABB Annual Meeting. [Abstract].
    6. Corean J, White SK, Schmidt RL, Walker BS, Fisher M, Metcalf RA (2020). The incremental value of anaerobic culture for detecting bacterial contamination in platelets: A systematic review and meta-analysis [Abstract].
    7. Wang Z, Zhe S, Tonna J, Sharma V, Metcalf RA (2020). Predicting intraoperative blood utilization in cardiothoracic surgery with machine learning [Abstract].
    8. Benson AB, Rollins M, Warrick C, Metcalf RA, Falkner D, Cail K, Clark EASEinersonBD (2020). Implementation of a new transfusion preparedness strategy on labor and delivery: safety and cost. [Abstract].
    9. Corean J, White SK, Blaylock R, Metcalf RA (2019). Impact of Screening Plateletpheresis Donors for Iron Deficiency at a Community Blood Center [Abstract].
    10. Metcalf RA, White S, Potter S, Barney R, White M, Hunter C, Blaylock R (2018). Risk Adjusted Blood Utilization Across All Inpatient Hospital Stays [Abstract]. AABB Annual Meeting. Boston, MA.
    11. Metcalf RA, Pagano MB, McGonigle A, Bakhtary S, Moayeri M, Andrews J (2017). ABO Leaders: A Community of Practice for Transfusion Medicine Education [Abstract].
    12. Khoobyari S, Katchatag BL, Metcalf RA, Van Gerwen M, Haley R, Gernsheimer T, Hess JR, and Pagano MB (2017). Quantitation of Isoagglutinin Titers of Platelets Stored in Additive Solution: Strategy for Hemolysis Risk Mitigation [Abstract].
    13. Khan J, Louzon MJ, Ramos P, Fernandez LR, Cruz-Cody V, Sen N, Hess JR, Metcalf RA (2017). Implementation and Evaluation of an Emergency Blood Refrigerator for Immediate Access to Universal Blood Components [Abstract].
    14. Metcalf RA, Pagano MB, Perkins JD, Montenovo MI (2017). Predicting Intraoperative Red Blood Cell Usage in Liver Transplantation [Abstract].
    15. Khan J, Pagano MB, Metcalf RA (2017). ABO-Mediated Hemolytic Disease of the Newborn Requiring Exchange Transfusion [Abstract].
    16. Murphy CH, Parakh RS, Metcalf RA, Pagano MB (2017). Transfusion Associated Chest Pain (TRACH): Descriptive Analysis at a Single Institution [Abstract].
    17. Pagano MB, Metcalf RA, Hess JR, Perkins JD, Montenovo MI (2017). A 1:1 Blood Component Transfusion Ratio during Liver Transplantation Decreases Blood Utilization [Abstract].
    18. Pagano MB, Metcalf RA, Ballard B, Bjur A, Buckmiller S, Clark CB, Hayden B, Hoffman N, Langston S, McCarrel M, Stephens D, Thomas M, Gernsheimer T, Hess JR (2016). Opening a new Transfusion Service Laboratory: A Blue-Print from Planning to Go-Live [abstract also published in Transfusion, 56(S4), AP71] [Abstract].
    19. Metcalf RA, Pagano MB, Hess JR, Gernsheimer T (2016). Risk-Based Decision Making: Whether to Screen Donors for Babesia in a Non-Endemic US State [abstract also published in Transfusion, 56(S4), SP418] [Abstract].
    20. Metcalf RA, Bakhtary S, Goodnough LT, Andrews J (2015). Hypotensive Transfusion Reactions in a Homogeneous Cohort of Patients [abstract also published in Transfusion, 55(S3), SP175] [Abstract].
    21. Metcalf RA, Baker S, Goodnough LT, Shah N (2015). Redesigned Coolers and Process Improvement Reduce Blood Product Wastage [abstract also published in Transfusion, 55(S3), SP253] [Abstract].
    22. Metcalf RA, Zhao S, Levy R, Lossos IS, Natkunam Y (2009). Characterization of D-cyclin Proteins in Hematolymphoid Neoplasms [Abstract].

    Other

    1. Metcalf RA, Lex A (2022). Taking Data Visualization for Blood Management to the Next Level and Beyond. American Association of Clinical Chemistry (AACC) Clinical Laboratory News.
    2. Pagano MB, Gniadek T, Jacobsen J, Lokhandawala P, Metcalf RA, Saifee NH, Stolla M, Storch E, Strauss D, Vassallo R, Young P (2021). The Association for the Advancement for Blood and Biotherapies (AABB) Association Bulletin #21-02: : Impact of the FDA Guidance “Bacterial Risk Control Strategies for Blood Collection Establishments and Transfusion Services to Enhance the Safety and Availability of Platelets for Transfusion”.

    Video/Film/CD/Web/Podcast

    1. Metcalf RA (2025). Platelet Transfusion: 2025 AABB and ICTMG International Platelet Transfusion Guidelines, JAMA Clinical Reviews Podcast with Executive Editor Dr. Gregory Curfman. [Podcast]. JAMA Network: JAMA Clinical Reviews. Available: https://jamanetwork.com/journals/jama/pages/jama-clinical-reviews.
    2. Metcalf RA (2023). Why Quality Management is Critical to the Long-term Success of Healthcare AI [Podcast]. ARUP Laboratories.
    3. Metcalf RA (2021). LabMind Podcast: Personalizing Transfusion Medicine [Podcast]. ARUP Laboratories.
    4. Metcalf RA (2020). Convalescent Plasma Therapy. LabMind Podcast hosted by Dr. Brian Jackson. [Podcast]. ARUP Laboratories.
    5. Metcalf RA (2020). Patient Blood Management [Video]. Clinical Chemistry Pearls.
    6. Metcalf RA (2017). Blood Utilization and The Transfusion Committee [Web]. Clincial Chemistry Pearls of Laboratory Medicine..