Salika M. Shakir

Salika M. Shakir, PhD, D(ABMM)

Languages spoken: English

  • Salika M. Shakir, PhD, D(ABMM) is the Medical Director of the Microbial Amplified Detection and AFB Laboratories and Assistant Professor of Pathology at the University of Utah, School of Medicine. After receiving a doctoral degree in Microbiology at the University of Oklahoma Health Sciences Center (OUHSC), she went on to pursue a research fellowship in Pediatric Infectious Diseases at OUHSC. She completed a fellowship training in Medical and Public Health Microbiology through the University of Utah and ARUP Laboratories, Salt Lake City, UT and is a diplomate of the American Board of Medical Microbiology. Her research and academic interests focus on the implementation of novel molecular assays for pathogen detection into the clinical laboratory and effective utilization of these new diagnostic tests. She has also successfully conducted several industry-sponsored clinical research projects for diagnostic assays/devices seeking FDA approval.

    Specialties

    • Pathology, Clinical

    Board Certification

    American Board of Medical Microbiology

  • Salika M. Shakir, PhD, D(ABMM) is the Medical Director of the Microbial Amplified Detection and AFB Laboratories and Assistant Professor of Pathology at the University of Utah, School of Medicine. After receiving a doctoral degree in Microbiology at the University of Oklahoma Health Sciences Center (OUHSC), she went on to pursue a research fellowship in Pediatric Infectious Diseases at OUHSC. She completed a fellowship training in Medical and Public Health Microbiology through the University of Utah and ARUP Laboratories, Salt Lake City, UT and is a diplomate of the American Board of Medical Microbiology. Her research and academic interests focus on the implementation of novel molecular assays for pathogen detection into the clinical laboratory and effective utilization of these new diagnostic tests. She has also successfully conducted several industry-sponsored clinical research projects for diagnostic assays/devices seeking FDA approval.

    Board Certification and Academic Information

    Academic Departments Pathology -Primary
    Board Certification
    American Board of Medical Microbiology

    Education history

    Fellowship Clinical Microbiology - University of Utah School of Medicine Fellow
    University of Oklahoma Health Sciences Center Postdoctoral Fellow
    Doctoral Training University of Oklahoma Health Sciences Center Ph.D.
    Microbiology - Bangalore University B.S.

    Selected Publications

    Journal Article

    1. Shakir SM, Otiso J, Keller G, Van Heule H, Osborn LJ, Cole N, Schuetz AN, Richter SS, Couturier MR (2022). Multicenter Evaluation of a Gradient Diffusion Method for Antimicrobial Susceptibility Testing of Helicobacter pylori. Microbiol Spectr, 10(2).
    2. Shakir SM, Gill R, Salberg J, Slechta ES, Feldman M, Fritsche T, Clarridge J, Sharp SE, Fisher MA (2021). Clinical Laboratory Perspective on Streptococcus halichoeri, an Unusual Nonhemolytic, Lancefield Group B Streptococcus Causing Human Infections. Emerg Infect Dis, 27(5), 1309–1316.
    3. Hanson KE, Barker AP, Hillyard DR, Gilmore N, Barrett JW, Orlandi RR, Shakir SM (2020). Self-Collected Anterior Nasal and Saliva Specimens versus Healthcare Worker-Collected Nasopharyngeal Swabs for the Molecular Detection of SARS-CoV-2. J Clin Microbiol, 58(11).
    4. Creager HM, Cabrera Barbara, Schnaubelt A, Cox JL, Cushman-Vokouna AM, Shakir SM, Tardif KD, Huang ML Jerome KR, Greninger AL, Drobysheva D, Spaulding U, Rogatcheva M, Bourzace KM, Hinrichs SH, Broadhurst MJ, Fey PD (2020). Clinical evaluation of the BioFire® Respiratory Panel 2.1 and detection of SARS-CoV-2. J Clin Virol, 129(2020), 104538.
    5. Shakir SM, Mansfield CR, Hays ED, Couturier MR, Hillyard DR (2020). Evaluation of a Novel High-Definition PCR Multiplex Assay for Simultaneous Detection of Tick-Borne Pathogens in Human Clinical Specimens. J Clin Microbiol, 58(3).
    6. Shakir SM, Goldbeck JM, Robison D, Eckerd AM, Chavez-Bueno S (2014). Genotypic and phenotypic characterization of invasive neonatal Escherichia coli clinical isolates. Am J Perinatol, 31(11), 975-82. (Read full article)
    7. Larabee JL, Shakir SM, Barua S, Ballard JD (2013). Increased cAMP in monocytes augments Notch signaling mechanisms by elevating RBP-J and transducin-like enhancer of Split (TLE). J Biol Chem, 288(30), 21526-36. (Read full article)
    8. Larabee JL, Maldonado-Arocho FJ, Pacheco S, France B, DeGiusti K, Shakir SM, Bradley KA, Ballard JD (2011). Glycogen synthase kinase 3 activation is important for anthrax edema toxin-induced dendritic cell maturation and anthrax toxin receptor 2 expression in macrophages. Infect Immun, 79(8), 3302-8. (Read full article)
    9. Larabee JL, Shakir SM, Hightower L, Ballard JD (2011). Adenomatous polyposis coli protein associates with C/EBP beta and increases Bacillus anthracis edema toxin-stimulated gene expression in macrophages. J Biol Chem, 286(22), 19364-72. (Read full article)
    10. Bryant-Hudson KM, Shakir SM, Ballard JD (2011). Autoregulatory characteristics of a Bacillus anthracis serine/threonine kinase. J Bacteriol, 193(8), 1833-42. (Read full article)
    11. Shakir SM, Bryant KM, Larabee JL, Hamm EE, Lovchik J, Lyons CR, Ballard JD (2009). Regulatory interactions of a virulence-associated serine/threonine phosphatase-kinase pair in Bacillus anthracis. J Bacteriol, 192(2), 400-9. (Read full article)
    12. Barua S, McKevitt M, DeGiusti K, Hamm EE, Larabee J, Shakir S, Bryant K, Koehler TM, Blanke SR, Dyer D, Gillaspy A, Ballard JD (2008). The mechanism of Bacillus anthracis intracellular germination requires multiple and highly diverse genetic loci. Infect Immun, 77(1), 23-31. (Read full article)
    13. McKevitt MT, Bryant KM, Shakir SM, Larabee JL, Blanke SR, Lovchik J, Lyons CR, Ballard JD (2007). Effects of endogenous D-alanine synthesis and autoinhibition of Bacillus anthracis germination on in vitro and in vivo infections. Infect Immun, 75(12), 5726-34. (Read full article)

    Review

    1. Shakir SM, Shakir FA, Couturier MR (2023). Updates to the Diagnosis and Clinical Management of Helicobacter pylori Infections. . [Review]. Clinical Chemistry (Chicago), 69(8), 869-880.
    2. Kukull B, Shakir SM, Hanson KE (2022). Performance of Non-nasopharyngeal Sample Types for Molecular Detection of SARS-CoV-2. [Review]. Clin Lab Med, 42(2), 249-259.

    Book Chapter

    1. Fisher MA, Shakir SM, Lopansri BK (2022). Strain Typing Using Next-Generation Sequencing . In Clinical Microbiology Procedures Handbook (4th). Washington DC/: ASM Press.

    Case Report

    1. Liu BM, Carlisle CP, Fisher MA, Shakir SM (2021). The Brief Case: Capnocytophaga sputigena Bacteremia in a 94-Year-Old Male with Type 2 Diabetes Mellitus, Pancytopenia, and Bronchopneumonia. J Clin Microbiol, 59(7).
    2. Liu BM, Carlisle CP, Fisher MA, Shakir SM (2021). Closing the Brief Case: Capnocytophaga sputigena Bacteremia in a 94-Year-Old Male with Type 2 Diabetes Mellitus, Pancytopenia, and Bronchopneumonia. J Clin Microbiol, 59(7).
    3. Shakir SM, Powers-Fletcher MV, Slechta ES, Fisher MA (2017). Helicobacter canis bacteraemia and cellulitis in a patient with end-stage renal disease. JMM Case Rep, 4(11), e005126. (Read full article)

    Letter

    1. Shakir SM, Barker AP, Hillyard DR, Gilmore N, Barrett JW, Orlandi RR, Hanson KE (2020). Combined Self-collected Anterior Nasal and Oropharyngeal Specimens versus Provider-collected Nasopharyngeal Swabs for the Detection of SARS-CoV-2 [Letter to the editor]. J Clin Microbiol.

    Other

    1. Shakir, SM (2021). Group B Streptococcal Disease.
    2. Shakir SM (2021). Vaginitis - Bacterial Vaginosis, Vulvovaginal Candidiasis, and Trichomoniasis.
    3. Shakir SM (2020). Sexually Transmitted Infections.
    4. Shakir SM (Feb 2019). Respiratory Viruses.
    5. Shakir SM (Feb 2019). Respiratory Syncytial Virus – RSV.

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