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Specialties
Board Certification
American Board of Psychiatry & Neurology (Neurology)Patient Rating
4.9 /5( out of 45 reviews )The patient rating score is an average of all responses on our patient experience survey. The rating averages scores for all questions about care from our providers.
The scale on which responses are measured is 1 to 5 with 5 being the best score.
Patient Comments
Patient comments are gathered from our patient experience survey and displayed in their entirety. For the convenience of our visitors, some patient comments have been translated from their original language into English while preserving their original meaning as accurately as possible. Patients are de-identified for confidentiality and patient privacy.
October 23, 2025CLINICAL NEUROSCIENCES CENTERDr. Clardy inspires confidence and has an excellent manner.
October 22, 2025CLINICAL NEUROSCIENCES CENTERShe is very caring and intelligent. Best neurologist I've seen by a mile.
October 10, 2025CLINICAL NEUROSCIENCES CENTERI absolutely love her! Dr. Clardy is so knowledgeable about my condition and treatment options while being personable at the same time.
September 11, 2025CLINICAL NEUROSCIENCES CENTERAppreciate time spoke about situation
August 28, 2025CLINICAL NEUROSCIENCES CENTERExcellent and knowledgeable physician. An expert in her field. Good sense of humor which we need with this depressing diagnoses we all have.
August 07, 2025CLINICAL NEUROSCIENCES CENTERDr. Clardy greatly impressed me with her knowledge of Auto Immune Limbic Encephalitis and the options for treatments at the stage that we are currently at. She came highly recommended and did not disappoint us.
May 09, 2025CLINICAL NEUROSCIENCES CENTERDr Clardy is an absolute gift to have as a Dr. Her level of care & compassion is unmatched. SheÕs able to talk to me in a down to earth manner that makes me feel understood & valued. I am so grateful for her dedication & help!
April 25, 2025CLINICAL NEUROSCIENCES CENTERI absolutely love Dr. Clardy. She always takes the time to talk to me and answer my questions without making me feel rushed or unimportant. She's so smart, stays up to date with advances in treatment options and is truly a kind person. Good doctors are hard to find. I would recommend her to anyone looking for a fantastic Neurologist.
April 03, 2025CLINICAL NEUROSCIENCES CENTERShe. Is. The. Best that I know
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Board Certification and Academic Information
Academic Departments Neurology -Professor
Population Health Sciences -Adjunct Associate Professor
Board Certification American Board of Psychiatry & Neurology (Neurology)Education history
Fellowship Autoimmune Neurology - Mayo Clinic Fellow Research Fellow ALS - Pennsylvania State University College of Medicine Postdoctoral Research Fellow Internship Medicine - Pennsylvania State University College of Medicine Intern Residency Neurology - Pennsylvania State University College of Medicine Resident Professional Medical Medicine/Cell and Molecular Biology - Pennsylvania State University College of Medicine M.D., Ph.D. Research Fellow Neurology - Pennsylvania State University College of Medicine Research Fellow Undergraduate Major: Biology; Minor: Psychology - Elizabethtown College B.S. Selected Publications
Journal Article
- Hoshina Y, Seay M, Vegunta S, Stulberg EL, Wright MA, Wong KH, Smith TL, Shimura D, Clardy SL (2024). Isolated Optic Neuritis: Etiology, Characteristics, and Outcomes in a US Mountain West Cohort. J Neuroophthalmol, 45(1), 36-43. (Read full publication)
- Hoshina Y, Moser C, Wright MA, Sunderman E, Livsey CT, Spoth E, Clardy SL, Cliatt Brown CJ (2025). C9orf72 Gene-Associated Frontotemporal Dementia Mimicking Autoimmune Pathology. Neurologist, 30(1), 42-44. (Read full publication)
- Wright MA, Guasp M, Lachner C, Day GS, Gombolay G, Titulaer MJ, Clardy SL (2024). Electroconvulsive therapy in N-methyl-d-aspartate receptor encephalitis: A retrospective cohort and scoping review of literature. J Neuroimmunol, 392, 578369. (Read full publication)
- Hoshina Y, Delic A, Wong KH, Lyden S, Kadish R, Smith TL, Wright MA, Shimura D, Clardy SL (2023). Vasculitis in the Central Nervous System: Etiology, Characteristics, and Outcomes in a Large Single-Center Cohort. Neurohospitalist, 14(2), 129-139. (Read full publication)
- Noroozi Gilandehi S, Wong KH, Francis T, Wright MA, Lord J, Stehlik J, Kemeyou L, Smith T, Clardy SL (2024). Cardiac Involvement in Neurosarcoidosis: A Single-Center Investigation. Neurol Neuroimmunol Neuroinflamm, 11(2), e200196. (Read full publication)
- Xu J, Erlendsson S, Singh M, Holling GA, Regier M, Ibiricu I, Einstein J, Hantak MP, Day GS, Piquet AL, Smith TL, Clardy SL, Whiteley AM, Feschotte C, Briggs JAG, Shepherd JD (2024). PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome. Cell, 187(4), 831-845.e19. (Read full publication)
- Hoshina Y, Wong KH, Galli J, Bacharach R, Klein J, Lebiedz-Odrobina D, Rose JW, Trump B, Hull C, Greenlee JE, Clardy SL (2023). Neurologic involvement in seronegative primary Sjögren's syndrome with positive minor salivary gland biopsy: a single-center experience. Front Neurol, 14, 1174116. (Read full publication)
- De Almeida BI, Smith TL, Delic A, Esquibel L, Galli J, Millsap L, Paz Soldn MM, Cortez MM, Rose J, Greenlee JE, Gundlapalli AV, Hill HR, Wong KH, Clardy SL (2023). Neurologic Manifestations of Common Variable Immunodeficiency: Impact on Quality of Life. Neurol Neuroimmunol Neuroinflamm, 10(3). (Read full publication)
- Flanagan EP, Geschwind MD, Lopez-Chiriboga AS, Blackburn KM, Turaga S, Binks S, Zitser J, Gelfand JM, Day GS, Dunham SR, Rodenbeck SJ, Clardy SL, Solomon AJ, Pittock SJ, McKeon A, Dubey D, Zekeridou A, Toledano M, Turner LE, Vernino S, Irani SR (2022). Autoimmune Encephalitis Misdiagnosis in Adults. JAMA Neurol, 80(1), 30-39. (Read full publication)
- Poon JT, Salzman K, Clardy SL, Paz Soldan MM (2022). Adrenal Crisis Presenting as Recurrent Encephalopathy Mimicking Autoimmune, Infectious Encephalitis, and Common Variable Immune Deficiency: A Case Report. Neurologist, 27(4), 206-210. (Read full publication)
- Kadish R, Clardy SL, Royston M, Tanvir I, Parker T, Biskupiak J, Kielhorn A (2021). Clinical burden of relapses in aquaporin-4 immunoglobulin G-positive neuromyelitis optica spectrum disorder: A single center cohort analysis. J Neuroimmunol, 362, 577761. (Read full publication)
- Di Sera T, Velinder M, Ward A, Qiao Y, Georges S, Miller C, Pitman A, Richards W, Ekawade A, Viskochil D, Carey JC, Pace L, Bale J, Clardy SL, Andrews A, Botto L, Marth G (2021). Gene.iobio: an interactive web tool for versatile, clinically-driven variant interrogation and prioritization. Sci Rep, 11(1), 20307. (Read full publication)
- Villani LA, Stulberg EL, Abbatemarco JR, Davidson CJ, Kadish R, Renner DR, Soldan MMP, Rose JW, Clardy SL, Greenlee JE (2021). Biopsy-proven PML in an HIV-negative patient with discoid lupus: Failure to detect JC virus in CSF. Clin Neurol Neurosurg, 209, 106843. (Read full publication)
- Williams JP, Abbatemarco JR, Galli JJ, Rodenbeck SJ, Peterson LK, Haven TR, Street M, Rose JW, Greenlee JE, Soldan MMP, Clardy SL (2021). Aquaporin-4 Autoantibody Detection by ELISA: A Retrospective Characterization of a Commonly Used Assay. Mult Scler Int, 2021, 8692328. (Read full publication)
- Abbatemarco JR, Galli JR, Sweeney ML, Carlson NG, Samara VC, Davis H, Rodenbeck S, Wong KH, Paz Soldan MM, Greenlee JE, Rose JW, Delic A, Clardy SL (2021). Modern Look at Transverse Myelitis and Inflammatory Myelopathy: Epidemiology of the National Veterans Health Administration Population. Neurol Neuroimmunol Neuroinflamm, 8(6). (Read full publication)
- Guidon AC, Burton LB, Chwalisz BK, Hillis J, Schaller TH, Amato AA, Betof Warner A, Brastianos PK, Cho TA, Clardy SL, Cohen JV, Dietrich J, Dougan M, Doughty CT, Dubey D, Gelfand JM, Guptill JT, Johnson DB, Juel VC, Kadish R, Kolb N, LeBoeuf NR, Linnoila J, Mammen AL, Martinez-Lage M, Mooradian MJ, Naidoo J, Neilan TG, Reardon DA, Rubin KM, Santomasso BD, Sullivan RJ, Wang N, Woodman K, Zubiri L, Louv WC, Reynolds KL (2021). Consensus disease definitions for neurologic immune-related adverse events of immune checkpoint inhibitors. J Immunother Cancer, 9(7). (Read full publication)
- Rodenbeck SJ, Clardy SL (2021). Thyroid antibodies: the end of an era? Brain Commun, 3(2), fcab030. (Read full publication)
- Webb LM, Chen JJ, Aksamit AJ, Bhattacharyya S, Chwalisz BK, Balaban D, Manzano GS, Ali AS, Lord J, Clardy SL, Samudralwar RD, Mao-Draayer Y, Garrity JA, Bhatti MT, Turner LE, Flanagan EP (2020). A multi-center case series of sarcoid optic neuropathy. J Neurol Sci, 420, 117282. (Read full publication)
- Lord J, Paz Soldan MM, Galli J, Salzman KL, Kresser J, Bacharach R, DeWitt LD, Klein J, Rose J, Greenlee J, Clardy SL (2020). Neurosarcoidosis: Longitudinal experience in a single-center, academic healthcare system. Neurol Neuroimmunol Neuroinflamm, 7(4). (Read full publication)
- Galli JR, Austin SD, Greenlee JE, Clardy SL (2018). Stiff person syndrome with Anti-GAD65 antibodies within the national veterans affairs health administration. Muscle Nerve, 58(6), 801-804. (Read full publication)
- Lpez-Chiriboga AS, Clardy SL (2017). Emerging Subspecialties in Neurology: Autoimmune neurology. Neurology, 89(11), e129-e133. (Read full publication)
- Abenroth DC, Smith AG, Greenlee JE, Austin SD, Clardy SL (2017). Lambert-Eaton myasthenic syndrome: Epidemiology and therapeutic response in the national veterans affairs population. Muscle Nerve, 56(3), 421-426. (Read full publication)
- Sweeney M, Galli J, McNally S, Tebo A, Haven T, Thulin P, Clardy SL (2017). Delayed LGI1 seropositivity in voltage-gated potassium channel (VGKC)-complex antibody limbic encephalitis. BMJ Case Rep, 2017. (Read full publication)
- Guo Y, Weigand SD, Popescu BF, Lennon VA, Parisi JE, Pittock SJ, Parks NE, Clardy SL, Howe CL, Lucchinetti CF (2017). Pathogenic implications of cerebrospinal fluid barrier pathology in neuromyelitis optica. Acta Neuropathol, 133(4), 597-612. (Read full publication)
- Galli JR, Clardy SL, Paz Soldn MM (2016). Adult-onset Opsoclonus-Myoclonus Syndrome Associated With Ganglionic Acetylcholine Receptor Autoantibody. Neurologist, 21(6), 99-100. (Read full publication)
- Wynn D, Merriman J, Patel AB, Hitchcock YJ, Garrido-Laguna I, Renner D, Clardy SL (2016). Paraneoplastic opsoclonus associated with squamous cell carcinoma of the tongue. Clin Neurol Neurosurg, 149, 11-4. (Read full publication)
- McKasson M, Clardy SL, Clawson SA, Hill KE, Wood B, Carlson N, Bromberg M, Greenlee JE (2016). Voltage-gated calcium channel autoimmune cerebellar degeneration: Case and study of cytotoxicity. Neurol Neuroimmunol Neuroinflamm, 3(3), e222. (Read full publication)
- Heiry M, Afra P, Matsuo F, Greenlee JE, Clardy SL (2015). Improvement of GAD65-associated autoimmune epilepsy with testosterone replacement therapy. Neurol Neuroimmunol Neuroinflamm, 2(5), e142. (Read full publication)
- Greenlee JE, Clawson SA, Hill KE, Wood B, Clardy SL, Tsunoda I, Carlson NG (2015). Anti-Yo antibody uptake and interaction with its intracellular target antigen causes Purkinje cell death in rat cerebellar slice cultures: a possible mechanism for paraneoplastic cerebellar degeneration in humans with gynecological or breast cancers. PLoS One, 10(4), e0123446. (Read full publication)
- Su XW, Clardy SL, Stephens HE, Simmons Z, Connor JR (2014). Serum ferritin is elevated in amyotrophic lateral sclerosis patients. Amyotroph Lateral Scler Frontotemporal Degener, 16(1-2), 102-7. (Read full publication)
- Popescu BF, Guo Y, Jentoft ME, Parisi JE, Lennon VA, Pittock SJ, Weinshenker BG, Wingerchuk DM, Giannini C, Metz I, Brck W, Shuster EA, Carter J, Boyd CD, Clardy SL, Cohen BA, Lucchinetti CF (2014). Diagnostic utility of aquaporin-4 in the analysis of active demyelinating lesions. Neurology, 84(2), 148-58. (Read full publication)
- Tobin WO, Lennon VA, Komorowski L, Probst C, Clardy SL, Aksamit AJ, Appendino JP, Lucchinetti CF, Matsumoto JY, Pittock SJ, Sandroni P, Tippmann-Peikert M, Wirrell EC, McKeon A (2014). DPPX potassium channel antibody: frequency, clinical accompaniments, and outcomes in 20 patients. Neurology, 83(20), 1797-803. (Read full publication)
- Greenlee JE, Clawson SA, Hill KE, Wood B, Clardy SL, Tsunoda I, Jaskowski TD, Carlson NG (2014). Neuronal uptake of anti-Hu antibody, but not anti-Ri antibody, leads to cell death in brain slice cultures. J Neuroinflammation, 11, 160. (Read full publication)
- Fryer JP, Lennon VA, Pittock SJ, Jenkins SM, Fallier-Becker P, Clardy SL, Horta E, Jedynak EA, Lucchinetti CF, Shuster EA, Weinshenker BG, Wingerchuk DM, McKeon A (2014). AQP4 autoantibody assay performance in clinical laboratory service. Neurol Neuroimmunol Neuroinflamm, 1(1), e11. (Read full publication)
- Clardy SL, Lucchinetti CF, Krecke KN, Lennon VA, OToole O, Weinshenker BG, Boyd CD, Krieger S, McGraw C, Guo Y, Pittock SJ (2014). Hydrocephalus in neuromyelitis optica. Neurology, 82(20), 1841-3. (Read full publication)
- Philipps G, Alisanski SB, Pranzatelli M, Clardy SL, Lennon VA, McKeon A (2014). Purkinje cell cytoplasmic antibody type 1 (anti-Yo) autoimmunity in a child with Down syndrome. JAMA Neurol, 71(3), 347-9. (Read full publication)
Review
- Clardy SL, Smith TL (2024). Therapeutic Approach to Autoimmune Neurologic Disorders. [Review]. Continuum (Minneap Minn), 30(4), 1226-1258. (Read full publication)
- Clardy SL, Pittock SJ, Aktas O, Nakahara J, Isobe N, Centonze D, Fam S, Kielhorn A, Yu JC, Jansen J, Zhang I (2024). Network Meta-analysis of Ravulizumab and Alternative Interventions for the Treatment of Neuromyelitis Optica Spectrum Disorder. [Review]. Neurol Ther, 13(3), 535-549. (Read full publication)
- Kadish R, Clardy SL (2024). Epidemiology of paraneoplastic neurologic syndromes. [Review]. Handb Clin Neurol, 200, 57-77. (Read full publication)
- Hoshina Y, Galli J, Wong KH, Kovacsovics T, Steinbach M, Salzman KL, McNally JS, Lancaster E, Paz Soldn MM, Clardy SL (2022). GABA-A Receptor Encephalitis After Autologous Hematopoietic Stem Cell Transplant forMultiple Myeloma: Three Cases and Literature Review. [Review]. Neurol Neuroimmunol Neuroinflamm, 9(6). (Read full publication)
- Greenlee JE, Carlson NG, Abbatemarco JR, Herdlevr I, Clardy SL, Vedeler CA (2022). Paraneoplastic and Other Autoimmune Encephalitides: Antineuronal Antibodies, T Lymphocytes, and Questions of Pathogenesis. [Review]. Front Neurol, 12, 744653. (Read full publication)
- Abbatemarco JR, Rodenbeck SJ, Day GS, Titulaer MJ, Yeshokumar AK, Clardy SL (2021). Autoimmune Neurology: The Need for Comprehensive Care. [Review]. Neurol Neuroimmunol Neuroinflamm, 8(5). (Read full publication)
- Sanchez JMS, McNally JS, Cortez MM, Hemp J, Pace LA, Clardy SL (2020). Neuroimmunogastroenterology: At the Interface of Neuroimmunology and Gastroenterology. [Review]. Front Neurol, 11, 787. (Read full publication)
- Piquet AL, Clardy SL (2018). Infection, Immunodeficiency, and Inflammatory Diseases in Autoimmune Neurology. [Review]. Semin Neurol, 38(3), 379-391. (Read full publication)
- Galli J, Clardy SL, Piquet AL (2017). NMDAR Encephalitis Following Herpes Simplex Virus Encephalitis. [Review]. Curr Infect Dis Rep, 19(1), 1. (Read full publication)
- Sweeney M, Sweney M, Soldn MM, Clardy SL (2016). Antineuronal Nuclear Autoantibody Type 1/Anti-Hu-Associated Opsoclonus Myoclonus and Epilepsia Partialis Continua: Case Report and Literature Review. [Review]. Pediatr Neurol, 65, 86-89. (Read full publication)
- Clardy SL, Lennon VA, Dalmau J, Pittock SJ, Jones HR Jr, Renaud DL, Harper CM Jr, Matsumoto JY, McKeon A (2013). Childhood onset of stiff-man syndrome. [Review]. JAMA Neurol, 70(12), 1531-6. (Read full publication)
Editorial
- Greenlee JE, Carlson NG, Abbatemarco JR, Herdlevr I, Clardy SL, Vedeler CA (2022). Editorial: Autoimmunity and the Brain: Paraneoplastic Neurological Injury and Beyond. Front Neurol, 13, 900130. (Read full publication)
- Abbatemarco JR, Clardy SL (2021). The Pursuit of Precision in Paraneoplastic Neurologic Disease. Neurol Neuroimmunol Neuroinflamm, 8(4). (Read full publication)
Abstract
- Galli JR, Clardy SL, Paz Soldn MM (2015). Ganglionic acetylcholine receptor autoantibody-associated opsoclonus-myoclonus syndrome [Abstract]. Annals of Neurology, 78(S19), S75.
Other
- Di Sera T, Velinder M, Ward A, Qiao Y, Georges S, Miller C, Pitman A, Richards W, Ekawade A, Viskochil D, Carey JC, Pace L, Bale J, Clardy SL, Andrews A, Botto L, Marth G (2022). Author Correction: Gene.iobio: an interactive web tool for versatile, clinically-driven variant interrogation and prioritization. Sci Rep (12(1), p. 5800). England. (Read full publication)
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