What Is Brain-Responsive Neurostimulation?

Brain-responsive neurostimulation is a type of monitoring doctors use to prevent seizures caused by epilepsy. This type of stimulation responds to your brain's electrical activity to stop a seizure before it happens.

Brain-responsive neurostimulation prevents seizures by:

  • monitoring the electrical activity in your brain at all times, 
  • detecting any unusual activity in your brain that may lead to a seizure, and
  • delivering a small electrical pulse to your brain to prevent a seizure from happening.

Brain-responsive neurostimulation sends electrical pulses to your brain milliseconds after it detects any unusual brain activity that could cause a seizure. In this way, it gives you treatment when you need it—similar to how pacemakers work in the heart.

Responsive neurostimulation is sometimes called deep brain stimulation. The device that monitors your brain's activity and sends pulses is called RNS® or the Neuropace RNS® System. 

How Successful is Brain-Responsive Neurostimulation?

Many people have fewer seizures after having brain-responsive neurostimulation.

The RNS® System continues to work better over time:

  • After three years, most patients will have 60 percent fewer seizures.
  • After seven years, most patients will have 72 percent fewer seizures. 

Will Brain-Responsive Neurostimulation Make My Seizures Go Away Permanently?

No. RNS® won't make your seizures go away completely. But many people have at least a couple months without having any seizures at all.

Some people don't have seizures for a year or longer after having RNS®.

Who Should Get This Treatment?

Brain-responsive neurostimulation is best for adults who've tried at least two antiseizure medications but still get seizures often. Your seizures should also be serious and interfere with your daily activities.

Find a NeuroPace RNS Specialist


For most types of epilepsy surgery, brain surgeons need to remove the part of your brain that's causing seizures. But with brain-responsive neurostimulation, doctors don't need to remove part of your brain or any brain tissue. Instead, your doctor will implant the Neuropace device into the part of your brain that's causing seizures. 

The Neuropace device can then release an electrical pulse to that part of your brain to stop a seizure before it starts.

The Neuropace device is tiny. It also can't be seen once it's implanted.

RNS® is also reversible. Your doctor can turn the device off. You can also have surgery to remove the device if you would like. But you don't have to get the device surgically removed once you stop using it. That's because it's safe to leave the RNS® device inside your brain tissue.

Neuropace Surgery Recovery

Most patients stay in the hospital for one to two days after having surgery. You should be able to get back to most of your regular activities once you return home.

After the RNS® device is implanted, no one will be able to tell you have it because they won't be able to see it.

Next Steps

You can make an appointment with a neurologist  if you've tried at least two antiseizure medications but still get seizures.

Hear From Our Patients

For 25 years, Danielle has struggled with epilepsy. Every two to three weeks, she would suffer from 10 or more seizures per day for an entire week. As a worker in the medical field, she knew these seizures were affecting her career and her ability to do her job. Her neurologist at University of Utah Health understood her worries and suggested she try the Neuropace RNS System. The device was implanted in her brain in April 2018. Since then, she no longer experiences any seizures or symptoms.

Read Danielle's Story

Danielle Holton, epilepsy patient

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