John J. Zone,
MD
Chief of Dermatology Section
Languages Spoken: English
John J. Zone, MD has specialized expertise in the diagnosis and treatment of blistering diseases of the skin. This includes dermatitis herpetiformis, linear IgA disease, pemphigus and pemphigoid. He is board certified in dermatology, immunodermatology and internal medicine. He runs both a research and clinical laboratory dedicated to diagnosis, treatment and research of blistering diseases. Dr. Zone deals primarily with the practice of medical dermatology and expert management of dermatitis herpetiformis, gluten intolerence, linear IgA disease, pemphigus, pemphigoid, lichen planus and oral ulcers that are frequently related to immune conditions.
Clinical Locations
801-581-2955
Dermatology, Area E
801-581-2955
Fax: (801) 585-2702
Board Certification and Academic Information
| Academic Departments | Dermatology
-
Professor Pathology - Adjunct Professor |
| Board Certification | American Board of Dermatology (Dermatology) American Board of Dermatology (Sub: Clin&Lab Derm Imm) American Board of Internal Medicine (Internal Medicine) |
Patient Rating
The Patient Rating score is an average of all responses to care provider related questions on our nationally-recognized Press Ganey Patient Satisfaction Survey.
Responses are measured on a scale of 1 to 5 with 5 being the best score.
Likelihood of recommending care provider
4.9/ 5
Care provider's explanation of condition/problem
4.9/ 5
Care provider's effort to include me in decisions
4.9/ 5
Wait time at clinic
4.9/ 5
Care provider's concern for questions & worries
4.9/ 5
Patient Comments
Patient comments are gathered from our Press Ganey Patient Satisfaction Survery and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
UofU Patient
May 03, 2022
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Dr. Zone is the best!!!
UofU Patient
April 25, 2022
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Dr. Zone is awesome.
UofU Patient
April 24, 2022
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Don't let Dr Zone ever retire
UofU Patient
March 22, 2022
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Dr Zone is a great doctor. I appreciate all he has done for me. He listens and has a great personality.
UofU Patient
March 21, 2022
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Dr Zone was completely accurate on the medication he gave me.
UofU Patient
February 23, 2022
UH HOSPITALS AND CLINICS
Dr. Zone seemed very busy and in a hurry. He usually spends a lot of time discussing everything but this day he seemed to be in a hurry. He is still a very good doctor.
UofU Patient
February 12, 2022
UH HOSPITALS AND CLINICS
I am not in the habit of recommending.
UofU Patient
February 12, 2022
UH HOSPITALS AND CLINICS
As always, Dr. Zone takes the time to listen and make the experience as comfortable as possible.
UofU Patient
January 31, 2022
UH HOSPITALS AND CLINICS
He is so smart and so kind. I really appreciate him.
UofU Patient
December 19, 2021
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Dr Zone is one of the best doctors I've seen! He listened intently to my concerns and he moved mountains to help me get treatment for my concerns. I am so thankful that he is a part of my care team!
UofU Patient
October 31, 2021
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
He is the best.
UofU Patient
October 18, 2021
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Dr. Zone and whole staff are by far the best.
UofU Patient
October 12, 2021
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
My wife and I always recommend Dr John Zone. We are both very pleased with everything he does for me.
UofU Patient
September 18, 2021
UH HOSPITALS AND CLINICS
Dr. Zone is one of the best doctors I've ever been to. He answers all of my questions and makes sure I understand what needs to be done. He never belittles my concerns. And of course, he's extremely knowledgeable so I trust him.
UofU Patient
July 25, 2021
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Dr Zone is awesome
UofU Patient
May 17, 2021
UH HOSPITALS AND CLINICS
John Zone is an institution. There's no one better. I am alive because of his care.
UofU Patient
May 11, 2021
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Dr. Zone explained everything.
UofU Patient
May 08, 2021
UH HOSPITALS AND CLINICS
I have been seeing Dr Zone for over 30 years and I have been very impressed with his professionalism as well as his knowledge. He actually diagnosed my melanoma and sent me to Huntsman for treatment. I so appreciate him!
UofU Patient
May 06, 2021
UH HOSPITALS AND CLINICS
Good
UofU Patient
May 02, 2021
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
I love Dr. Zone and actually look forward to meeting with him. He truly listens and addresses all of my concerns.
UofU Patient
April 27, 2021
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
The provider took extra time to address my concerns.
UofU Patient
March 28, 2021
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
I have the utmost confidence in Dr. Zone's care. He stays up to date on the newest treatment options and we've tried many different medications over the last 8+ years to finally find something that works well for me. The newest drug is an off-label use and extremely expensive but he and the staff have really gone the extra mile to try to provide that for me with samples and multiple insurance appeals. I appreciate their efforts so much. And his easy-going personality actually makes doctor visits fun!
UofU Patient
March 21, 2021
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
excellent doctor.
UofU Patient
March 09, 2021
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
all good
UofU Patient
January 30, 2021
UH HOSPITALS AND CLINICS
Dr. Zone is the best.
UofU Patient
January 08, 2021
UH HOSPITALS AND CLINICS
DR. ZONE IS SUPERB!!
UofU Patient
January 02, 2021
UH HOSPITALS AND CLINICS
excellent experience with everyone.
UofU Patient
December 27, 2020
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
De. Zine is always very good to listen to ALL my concerns.
UofU Patient
December 13, 2020
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
I always leave with all of my questions answered and a clear understanding of my medications/treatment plan until the next visit.
UofU Patient
November 01, 2020
UH HOSPITALS AND CLINICS
good
UofU Patient
October 22, 2020
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Dr. Zone is the all-around amazing doctor! He's extremely knowledgeable and experienced, compassionate, polite, funny and goes the extra mile to provide extraordinary care for his patients.
UofU Patient
October 21, 2020
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Dr. Zone is always pleasant and really explains/answers my questions to my satisfactions. He is also very thorough and of course very knowledgeable.
UofU Patient
October 14, 2020
UH HOSPITALS AND CLINICS
DR ZONE IS OUTSTANDING IN EVERY WAY!!
UofU Patient
October 04, 2020
UH HOSPITALS AND CLINICS
Dr. Zone is fantastic
UofU Patient
September 30, 2020
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
very good he is very knowledgeable and his practice I feel very satisfied with his care and his treatment he shows a lot of concern for his patience and is very knowledgeable.
UofU Patient
September 28, 2020
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
good experience
UofU Patient
September 22, 2020
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Love Dr. Zone! He's always on top of things and makes sure no Stone is left unturned.
UofU Patient
September 21, 2020
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Dr Zone is very thorough in his exams and always keeps me involved in relevant q&a if he comes across something I am not aware of.
UofU Patient
September 02, 2020
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
Dr. Zone is very mindful of patient's experience and explains his thinking about diagnoses and treatment very carefully.
UofU Patient
August 30, 2020
UH HOSPITALS AND CLINICS
Dr. Zone always does an excellent job!!!
UofU Patient
August 25, 2020
UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER
dr zone looked at some blood test results that were not the subject of my appointment. I greatly appreciated his willingness and ability to explain the results but also informed me of some factors that had led to the tests being prescribed by my GP.
UofU Patient
August 17, 2020
UH HOSPITALS AND CLINICS
all good
John J. Zone, MD has specialized expertise in the diagnosis and treatment of blistering diseases of the skin. This includes dermatitis herpetiformis, linear IgA disease, pemphigus and pemphigoid. He is board certified in dermatology, immunodermatology and internal medicine. He runs both a research and clinical laboratory dedicated to diagnosis, treatment and research of blistering diseases. Dr. Zone deals primarily with the practice of medical dermatology and expert management of dermatitis herpetiformis, gluten intolerence, linear IgA disease, pemphigus, pemphigoid, lichen planus and oral ulcers that are frequently related to immune conditions.
Academic Locations
Board Certification and Academic Information
| Academic Departments | Dermatology
-
Professor Pathology - Adjunct Professor |
| Board Certification | American Board of Dermatology (Dermatology) American Board of Dermatology (Sub: Clin&Lab Derm Imm) American Board of Internal Medicine (Internal Medicine) |
Research Interests
- Celiac Disease
- Immunopathology
- Bullous Disease
- Dermatitis Herpetiformis
- Melanoma
- Pemphigus
- Lichen Planus
- Linear IgA Disease
Education History
| Residency | SUNY - Buffalo Dermatology Resident, 1978 |
| Residency | SUNY at Syracuse Internal Medicine Resident, 1975 |
| Internship | SUNY at Syracuse Internal Medicine Intern, 1972 |
| Professional Medical | SUNY at Syracuse Medicine M.D., 1971 |
| Undergraduate | University of Notre Dame Premedical Sciences B.S., 1967 |
Selected Publications - Journal Articles
Journal Article
- Leiferman KM, Snook JP, Khalighi MA, Kuechle MK, Zone JJ (2021). Diagnostics for Dermatologic Diseases with Autoantibodies. J Appl Lab Med, 7(1), 165-196.
- Malone Jenkins S, Palmquist R, Kapron AL, Torr C, Best DH, Karren MA, Brunelli L, Yandell M, Tristani-Firouzi M, Dimmock D, Watts B, Botkin JR, Johnson A, Bonkowsky JL (2021). Addressing ethical and laboratory challenges for initiation of a rapid whole genome sequencing program. J Clin Transl Sci, 5(1), e177.
- Hashimoto T, Yamagami J, Zone JJ (2021). History, Diagnosis, Pathogenesis, and Nomenclature in Sublamina Densa-Type Linear IgA Disease. JAMA Dermatol, 157(8), 907-909.
- Cannon-Albright LA, Teerlink CC, Farnham JM, Thomas AW, Zone JJ, Leachman SA (2013). Linkage analysis of extended high-risk pedigrees replicates a cutaneous malignant melanoma predisposition locus on chromosome 9q21. J Invest Dermatol, 133(1), 128-34.
- Shigeta M, Saiki M, Tsuruta D, Ohata C, Ishii N, Ono F, Hamada T, Dainichi T, Furumura M, Zone JJ, Karpati S, Sitaru C, Hashimoto T (2012). Two Japanese cases of dermatitis herpetiformis associated each with lung cancer and autoimmune pancreatitis but showing no intestinal symptom or circulating immunoglobulin A antibodies to any known antigens. J Dermatol, 39(12), 1002-5.
- McCaughey C, Machan M, Bennett R, Zone JJ, Hull CM (2011). Pimecrolimus 1% cream for oral erosive lichen planus: a 6-week randomized, double-blind, vehicle-controlled study with a 6-week open-label extension to assess efficacy and safety. J Eur Acad Dermatol Venereol, 25(9), 1061-7.
- Zone JJ, Schmidt LA, Taylor TB, Hull CM, Sotiriou MC, Jaskowski TD, Hill HR, Meyer LJ (2011). Dermatitis herpetiformis sera or goat anti-transglutaminase-3 transferred to human skin-grafted mice mimics dermatitis herpetiformis immunopathology. J Immunol, 186(7), 4474-80.
- Jaskowski TD, Donaldson MR, Hull CM, Wilson AR, Hill HR, Zone JJ, Book LS (2010). Novel screening assay performance in pediatric celiac disease and adult dermatitis herpetiformis. J Pediatr Gastroenterol Nutr, 51(1), 19-23.
- Jaskowski TD, Hamblin T, Wilson AR, Hill HR, Book LS, Meyer LJ, Zone JJ, Hull CM (2009). IgA anti-epidermal transglutaminase antibodies in dermatitis herpetiformis and pediatric celiac disease. J Invest Dermatol, 129(11), 2728-30.
- Petersen MJ, Zone JJ (2008). The Relationship between Autoimmune Bullous Disease and Systemic Disorders. J Invest Dermatol, 128(E3), E28-30.
- Hull CM, Liddle M, Hansen N, Meyer LJ, Schmidt L, Taylor T, Jaskowski TD, Hill HR, Zone JJ (2008). Elevation of IgA anti-epidermal transglutaminase antibodies in dermatitis herpetiformis. Br J Dermatol, 159(1), 120-4.
- Donaldson MR, Book LS, Leiferman KM, Zone JJ, Neuhausen SL (2008). Strongly positive tissue transglutaminase antibodies are associated with Marsh 3 histopathology in adult and pediatric celiac disease. J Clin Gastroenterol, 42(3), 256-60.
- Zone JJ, Taylor T, Hull C, Schmidt L, Meyer L (2007). IgE basement membrane zone antibodies induce eosinophil infiltration and histological blisters in engrafted human skin on SCID mice. J Invest Dermatol, 127(5), 1167-74.
- Donaldson MR, Zone JJ, Schmidt LA, Taylor TB, Neuhausen SL, Hull CM, Meyer LJ (2007). Epidermal transglutaminase deposits in perilesional and uninvolved skin in patients with dermatitis herpetiformis. J Invest Dermatol, 127(5), 1268-71.
- Donaldson MR, Firth SD, Wimpee H, Leiferman KM, Zone JJ, Horsley W, OGorman MA, Jackson WD, Neuhausen SL, Hull CM, Book LS (2007). Correlation of duodenal histology with tissue transglutaminase and endomysial antibody levels in pediatric celiac disease. Clin Gastroenterol Hepatol, 5(5), 567-73.
- Zone JJ (2005). Skin manifestations of celiac disease. Gastroenterology, 128(4 Suppl 1), S87-91.
- Zone JJ, Egan CA, Taylor TB, Meyer LJ (2004). IgA autoimmune disorders: development of a passive transfer mouse model. J Investig Dermatol Symp Proc, 9(1), 47-51.
- Book L, Zone JJ, Neuhausen SL (2003). Prevalence of celiac disease among relatives of sib pairs with celiac disease in U.S. families. Am J Gastroenterol, 98(2), 377-81.
- Neuhausen SL, Feolo M, Camp NJ, Farnham J, Book L, Zone JJ (2002). Genome-wide linkage analysis for celiac disease in North American families. Am J Med Genet, 111(1), 1-9.
- Neuhausen SL, Weizman Z, Camp NJ, Elbedour K, Sheffield VC, Zone JJ, Carmi R (2002). HLA DQA1-DQB1 genotypes in Bedouin families with celiac disease. Hum Immunol, 63(6), 502-7.
- Zone JJ (2001). Clinical spectrum, pathogenesis and treatment of linear IgA bullous dermatosis. J Dermatol, 2811, 651-653.
- Lewis C, Book L, Black J, Sawitzke A, Cannon-Albright L, Zone J, Neuhausen S (2000). Celiac disease and human leukocyte antigen genotype: accuracy of diagnosis in self-diagnosed individuals, dosage effect, and sibling risk. J Pediatr Gastroenterol Nutr, 31(1), 22-7.
- Smith JB, Smith SW, Zone JJ (1998). Dermatitis herpetiformis and cigarette smoking. Gut, 43, 732.
- Zone JJ, Taylor TB, Kadunce DP, Chorzelski TP, Schachner LA, Huff JC, Meyer LJ, Petersen MJ (1996). IgA antibodies in chronic bullous disease of childhood react with 97 kDa basement membrane zone protein. J Invest Dermatol, 106(6), 1277-80.
- Marinkovich MP, Taylor TB, Keene DR, Burgeson RE, Zone JJ (1996). LAD-1, the linear IgA bullous dermatosis autoantigen, is a novel 120-kDa anchoring filament protein synthesized by epidermal cells. J Invest Dermatol, 106(4), 734-8.
- Thuong-Nguyen V, Kadunce DP, Hendrix JD, Gammon WR, Zone JJ (1993). Inhibition of neutrophil adherence to antibody by dapsone: a possible therapeutic mechanism of dapsone in the treatment of IgA dermatoses. J Invest Dermatol, 100(4), 349-55.
- Cannon-Albright LA, Goldgar De, Meyer LJ, Lewis CM, Anderson DE, Fountain JW, Hegi ME, Wiseman RW, Petty EM, Bale AE, Olopade OI, Diaz MO, Kwiatkowski DJ, Piepkorn MW, Zone JJ, Skolnick MH (1992). Assignment of a locus for familial melanoma MLM to chromosome 9p13-p22. Science, 258, 1148-1152.
- Cannon-Albright LA, Goldgar DE, Wright EC, Turco A, Jost M, Meyer LJ, Piepkorn M, Zone JJ, Skolnick MH (1990). Evidence against the reported linkage of the cutaneous melanoma-dysplastic nevus syndrome locus to chromosome Ip36. Am J Hum Genet, 46(5), 912-8.
- Zone J, Ward J, Boyce E, Schupbach C (1982). Penicillamine-induced pemphigus. JAMA, 247(19), 2705-7.
- Zone JJ, LaSalle BA, Provost TT (1980). Circulating immune complexes of IgA type in dermatitis herpetiformis. J Invest Dermatol, 75(2), 152-5.
Conference Proceedings
- Murrell DF, Marinovic B, Caux F, Prost C, Ahmed R, Wozniak K, Amagai M, Bauer J, Beissert S, Borradori L, Culton D, Fairley JA, Fivenson D, Jonkman MF, Marinkovich MP, Woodley D, Zone J, Aoki V, Bernard P, Bruckner-Tuderman L, Cianchini G, Venning V, Diaz L, Eming R, Grando SA, Hall RP, Hashimoto T, Herrero-Gonzlez JE, Hertl M, Joly P, Karpati S, Kim J, Chan Kim S, Korman NJ, Kowalewski C, Lee SE, Rubenstein DR, Sprecher E, Yancey K, Zambruno G, Zillikens D, Doan S, Daniel BS, Werth VP (2014). Definitions and outcome measures for mucous membrane pemphigoid: recommendations of an international panel of experts. J Am Acad Dermatol, United States, 72(1), 168-74.
- Chan LS, Ahmed AR, Anhalt GJ, Bernauer W, Cooper KD, Elder MJ, Fine JD, Foster CS, Ghohestani R, Hashimoto T, Hoang-Xuan T, Kirtschig G, Korman NJ, Lightman S, Lozada-Nur F, Marinkovich MP, Mondino BJ, Prost-Squarcioni C, Rogers RS 3rd, Setterfield JF, West DP, Wojnarowska F, Woodley DT, Yancey KB, Zillikens D, Zone JJ (2002). The first international consensus on mucous membrane pemphigoid: definition, diagnostic criteria, pathogenic factors, medical treatment, and prognostic indicators. Arch Dermatol, United States, 138(3), 370-9.
Case Report
- Jimenez A, Hull C, Zone J (2021). Rituximab therapy for a severe case of pretibial myxedema. JAAD Case Rep, 10, 28-30.
- Jimenez A, Hull C, Zone J (2019). Dermatitis herpetiformis resistant to dapsone due to dietary iodide ingestion. JAAD Case Rep, 5(8), 713-714.
Letter
- Taylor TB, Schmidt LA, Meyer LJ, Zone JJ (2015). Transglutaminase 3 present in the IgA aggregates in dermatitis herpetiformis skin is enzymatically active and binds soluble fibrinogen. [Letter to the editor]. J Invest Dermatol, 135(2), 623-625.
- Egan CA, Reddy D, Nie Z, Taylor TB, Schmidt LA, Meyer LJ, Petersen MJ, Hashimoto T, Marinkovich MP, Zone JJ (2001). IgG anti-LABD97 antibodies in bullous pemphigoid patients' sera react with the mid-portion of the BPAg2 ectodomain. [Letter to the editor]. J Invest Dermatol, 116(2), 348-50.
- Smith JB, Fowler JB, Zone JJ (1994). The effect of ibuprofen on serum dapsone levels and disease activity in dermatitis herpetiformis. [Letter to the editor]. Arch Dermatol, 130(2), 257-9.
- Zone JJ (1981). Potassium iodide and vasculitis. [Letter to the editor]. Arch Dermatol, 117(12), 758-9.