Lyska L. Emerson, MD

Journal Article

1. Zitnay RG, Herron MR, Carney KR, Potter S, Emerson LL, Weiss JA, Mendoza MC (2022). Mechanics of lung cancer: A finite element model shows strain amplification during early tumorigenesis. PLoS Comput Biol, 18(10), e1010153. (Read full article)
2. Cowman SJ, Fuja DG, Liu XD, Tidwell RSS, Kandula N, Sirohi D, Agarwal AM, Emerson LL, Tripp SR, Mohlman JS, Stonhill M, Garcia G, Conley CJ, Olalde AA, Sargis T, Ramirez-Torres A, Karam JA, Wood CG, Sircar K, Tamboli P, Boucher K, Maughan B, Spike BT, Ho TH, Agarwal N, Jonasch E, Koh MY (2020). Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer. Clin Cancer Res, 26(18), 4970-4982. (Read full article)
3. Cook GW, Benton MG, Akerley W, Mayhew GF, Moehlenkamp C, Raterman D, Burgess DL, Rowell WJ, Lambert C, Eng K, Gu J, Baybayan P, Fussell JT, Herbold HD, OShea JM, Varghese TK, Emerson LL (2020). Structural variation and its potential impact on genome instability: Novel discoveries in the EGFR landscape by long-read sequencing. PLoS One, 15(1), e0226340. (Read full article)
4. Corean J, Furtado LV, Kadri S, Segal JP, Emerson LL (2018). Cribriform-Morular Variant of Papillary Thyroid Carcinoma With Poorly Differentiated Features: A Case Report With Immunohistochemical and Molecular Genetic Analysis. Int J Surg Pathol, 27(3), 294-304. (Read full article)
5. Boylan KE, Larsen BT, Young BA, Downs-Kelly E, Panchabhai TS, Collum ES, Jensen L, Emerson LL (2018). Pulmonary Mycobacterial Spindle Cell Pseudotumor: A Report of 3 Cases Including a Practical Approach to Histopathologic Recognition of This Unusual Entity. Int J Surg Pathol, 26(7), 629-634. (Read full article)
6. Keefe AC, Hymas JC, Emerson LL, Ryan JJ (2017). An atypical presentation of cardiac tamponade and periorbital swelling in a patient with eosinophilic granulomatosis with polyangiitis: a case report. J Med Case Rep, 11(1), 271. (Read full article)
7. Zhang X, Bohner A, Bhuvanagiri S, Uehara H, Upadhyay AK, Emerson LL, Bondalapati S, Muddana SK, Fang D, Li M, Sandhu Z, Hussain A, Carroll LS, Tiem M, Archer B, Kompella U, Patil R, Ambati BK (2017). Targeted Intraceptor Nanoparticle for Neovascular Macular Degeneration: Preclinical Dose Optimization and Toxicology Assessment. Mol Ther, 25(7), 1606-1615. (Read full article)
8. Poruk KE, Firpo MA, Scaife CL, Adler DG, Emerson LL, Boucher KM, Mulvihill SJ (2013). Serum osteopontin and tissue inhibitor of metalloproteinase 1 as diagnostic and prognostic biomarkers for pancreatic adenocarcinoma. Pancreas, 42(2), 193-7. (Read full article)
9. Emerson LL, Layfield LJ (2012). Solitary peripheral pulmonary papilloma evaluation on frozen section: a potential pitfall for the pathologist. Pathol Res Pract, 208(12), 726-9. (Read full article)
10. Kulke MH, Benson AB, Bergsland E, Berlin JD, Blaszkowsky LS, Choti MA, Clark OH, Doherty GM, Eason J, Emerson L, Engstrom PF, Goldner WS, Heslin MJ, Kandeel F, Kunz PL, Kuvshinoff BW, Moley JF, Pillarisetty VG, Saltz L, Schteingart DE, Shah MH, Shibata S, Strosberg JR, Vauthey JN, White R, Yao JC, Freedman-Cass DA, Dwyer MA (2012). National Comprehensive Cancer Networks. J Natl Compr Canc Netw, 10(6), 724-64.
11. Wallander ML, Layfield LJ, Emerson LL, Mamalis N, Davis D, Tripp SR, Holden JA (2011). KIT mutations in ocular melanoma: frequency and anatomic distribution. Mod Pathol, 24(8), 1031-5. (Read full article)
12. Wallander ML, Emerson LL, Tripp S, Davis D, Mamalis N, Holden JA, Layfield LJ (August 2011). KIT and PDGFRA Mutations in Ocular Melanoma: Frequency and Anatomic Distribution. Mod Pathol, 24(8), 1031-5.
13. Goldfarb-Rumyantzev AS, Wright S, Ragasa R, Ostler D, Van Orden J, Smith L, Efimova E, Emerson L, Sandhu GS, Shihab F (2011). Factors associated with nonadherence to medication in kidney transplant recipients. Nephron Clin Pract, 117(1), c33-9. (Read full article)
14. Poruk KE, Firpo MA, Huerter LM, Scaife CL, Emerson LL, Boucher KM, Jones KA, Mulvihill SJ (2010). Serum platelet factor 4 is an independent predictor of survival and venous thromboembolism in patients with pancreatic adenocarcinoma. Cancer Epidemiol Biomarkers Prev, 19(10), 2605-10. (Read full article)
15. Alkhatib AA, Craig R, Tuteja AK, Emerson LL (2010). Progression of solitary rectal ulcer syndrome over a 2-year period. Gastrointest Endosc, 72(4), 853-4. (Read full article)
16. Scaife CL, Shea J, Emerson L, Boucher K, Firpo MA, Beckerle MC, Mulvihill SJ (2010). Prognostic significance of PINCH signalling in human pancreatic ductal adenocarcinoma. HPB (Oxford), 12(5), 352-8. (Read full article)
17. Peterson KA, Thomas KL, Hilden K, Emerson LL, Wills JC, Fang JC (2010). Comparison of esomeprazole to aerosolized, swallowed fluticasone for eosinophilic esophagitis. Dig Dis Sci, 55(5), 1313-9. (Read full article)
18. Wallander M, Layfield LJ, Jarboe E, Emerson L, Liu T, Thaker H, Holden J, Tripp S (2010). Follicular variant of papillary carcinoma: reproducibility of histologic diagnosis and utility of HBME-1 immunohistochemistry and BRAF mutational analysis as diagnostic adjuncts. Appl Immunohistochem Mol Morphol, 18(3), 231-5. (Read full article)
19. Wu X, Jeong EK, Emerson L, Hoffman J, Parker DL, Lu ZR (2010). Noninvasive evaluation of antiangiogenic effect in a mouse tumor model by DCE-MRI with Gd-DTPA cystamine copolymers. Mol Pharm, 7(1), 41-8.
20. Wu X, Feng Y, Jeong EK, Emerson L, Lu ZR (2009). Tumor characterization with dynamic contrast enhanced magnetic resonance imaging and biodegradable macromolecular contrast agents in mice. Pharm Res, 26(9), 2202-8. (Read full article)
21. Goldfarb-Rumyantzev AS, Shihab F, Emerson L, Mineau G, Schaefer C, Tang H, Hunter C, Naiman N, Smith L, Kerber R (2009). A population-based assessment of the familial component of acute kidney allograft rejection. Nephrol Dial Transplant, 24(8), 2575-83. (Read full article)
22. Feng Y, Emerson L, Jeong EK, Parker DL, Lu ZR (2009). Application of a biodegradable macromolecular contrast agent in dynamic contrast-enhanced MRI for assessing the efficacy of indocyanine green-enhanced photothermal cancer therapy. J Magn Reson Imaging, 30(2), 401-6. (Read full article)
23. Fang WS, Emerson LL, Hunt JP, Salzman KL (2009). An unusual sinonasal tumor: soft tissue perineurioma. AJNR Am J Neuroradiol, 30(2), 437-9. (Read full article)
24. Schwartz JL, Woods B, Emerson L, Andtbacka R (2009). Appendiceal adenocarcinoma arising after bone marrow transplantation for Non-Hodgkin Lymphoma: an unusual treatment dilemma. (6), 1.
25. De La O JP, Emerson LL, Goodman JL, Froebe SC, Illum BE, Curtis AB, Murtaugh LC (2008). Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia. Proc Natl Acad Sci U S A, 105(48), 18907-12. (Read full article)
26. Feng Y, Jeong EK, Mohs AM, Emerson L, Lu ZR (2008). Characterization of tumor angiogenesis with dynamic contrast-enhanced MRI and biodegradable macromolecular contrast agents in mice. Magn Reson Med, 60(6), 1347-52. (Read full article)
27. Vaidya A, Sun Y, Feng Y, Emerson L, Jeong EK, Lu ZR (2008). Contrast-enhanced MRI-guided photodynamic cancer therapy with a pegylated bifunctional polymer conjugate. Pharm Res, 25(9), 2002-11. (Read full article)
28. Emerson LL, Carney HM, Layfield LJ, Sherbotie JR (2008). Collecting duct carcinoma arising in association with BK nephropathy post-transplantation in a pediatric patient. A case report with immunohistochemical and in situ hybridization study. Pediatr Transplant, 12(5), 600-5. (Read full article)
29. Layfield LJ, Emerson L, Crim JR, Randall L (2008). Squamous differentiation and cytokeratin expression in an osteosarcoma: a case report and review of the literature. Clin Med Pathol, 1, 55-9. (Read full article)
30. Rowe LR, Mulvihill SJ, Emerson L, Gopez EV (2007). Subcutaneous tumor seeding following needle core biopsy of hepatocellular carcinoma. Diagn Cytopathol, 35(11), 717-21. (Read full article)
31. Yu M, Miller ME, Emerson L, Bentz BG, Clayton F, Data RE, Salzman KL, and Smith LM (October 2007). An Unusual case of an extraosseus ewing's sarcoma. J Clin Oncol, 25(30), 4845-8.
32. Emerson LL, Layfield LJ, and Frame R (Sep 2007). Pleomorphic olfactory neuroblastoma (esthesioneuroblastoma): histopathologic findings and clinical course. Histopathology, 51(3), 430-432.
33. Mohs AM, Nguyen T, Jeong EK, Feng Y, Emerson L, Zong Y, Parker DL, Lu ZR (2007). Modification of Gd-DTPA cystine copolymers with PEG-1000 optimizes pharmacokinetics and tissue retention for magnetic resonance angiography. Magn Reson Med, 58(1), 110-8. (Read full article)
34. Goulet CJ, Disario JA, Emerson L, Hilden K, Holubkov R, Fang JC (2007). In vivo evaluation of argon plasma coagulation in a porcine model. Gastrointest Endosc, 65(3), 457-62. (Read full article)
35. Rollins MD, Sudarshan S, Firpo MA, Etherington BH, Hart BJ, Jackson HH, Jackson JD, Emerson LL, Yang DT, Mulvihill SJ, Glasgow RE (2006). Anti-inflammatory effects of PPAR-gamma agonists directly correlate with PPAR-gamma expression during acute pancreatitis. J Gastrointest Surg, 10(8), 1120-30. (Read full article)
36. Emerson LL, Tripp SR, Baird BC, Layfield LJ, Rohr LR (2006). A comparison of immunohistochemical stain quality in conventional and rapid microwave processed tissues. Am J Clin Pathol, 125(2), 176-83. (Read full article)
37. Tanaka R, Emerson LL, Karwande SV, Schreiber G (2005). Growing pulmonary nodule with increased 18-fluorodeoxyglucose uptake in a former smoker. Chest, 127(5), 1848-51. (Read full article)
38. Tanaka R, Emerson LL, Karwande SV, Schreiker G (2005). Growing pulmonary nodule with increased 18-fluorodeoxyglucose uptake in a former smoker. Chest, 127(5), 1848-51.
39. Emerson L, Layfield L, Reiss R, Mulvihill S (2001). Malignant Islet Cell Tumor with Sarcomatous Differentiation. Mod Pathol, 14(11), 1187-91.
40. Dasgupta A, Emerson L (1998). Neutralization of cardiac toxins oleandrin, oleandrigenin, bufalin, and cinobufotalin by digibind: monitoring the effect by measuring free digitoxin concentrations. Life Sci, 63(9), 781-8. (Read full article)
41. Dasgupta A, Emerson L (1996). Interaction of valproic acid with nonsteroidal antiinflammatory drugs mefenamic acid and fenoprofen in normal and uremic sera: lack of interaction in uremic sera due to the presence of endogenous factors. Ther Drug Monit, 18(6), 654-9. (Read full article)

Case Report

1. Abou-Al-Shaar H, Gozal YM, Hunt JP, Shelton C, Emerson LL, Joyce E, Couldwell WT (2017). Multifocal cavernous hemangioma of the jugular foramen: a rare skull base vascular malformation. J Neurosurg, 131(1), 109-113. (Read full article)
2. Cirulis MM, Emerson LL, Bull DA, Hatton N, Nativi-Nicolai J, Hildebrandt GC, Ryan JJ (2016). Pulmonary arterial hypertension in primary amyloidosis. Pulm Circ, 6(2), 244-8. (Read full article)

Letter

1. Emerson LL, Layfield LJ, Frame R (2007). Pleomorphic olfactory neuroblastoma (esthesioneuroblastoma): histopathological findings and clinical course. [Letter to the editor]. Histopathology, 51(3), 430-2. (Read full article)

Abstract

1. Farkash E, Brousaides N, Nickeleit V, Papadimitriou J, Roberts IS, Emerson L, Pelle TD, McDaid J, Colvin R (2014). T Antigen Dependent Oncogenic Pathways are Active in Post-Transplant Tumors Driven by BK Polyoma Virus. 2014 World Transplant Congress, San Francisco, CA, Jul 26-31, 2014 [Abstract].
2. Hewitt K, Shea J, Johnston WC, Emerson L, Scaife C (2013). PINCH Expression in Pancreatic Neuroendocrine Tumors. 47th Annual Pancreas Club Meeting, Orlando, FL. May 17-18, 2013 [Abstract].
3. Fang JC, Hilden K, Gleich G, Emerson LL (2011). A Pilot Study of the Treatment of Eosinophilic Esophagitis with Omalizumab, Digestive Disease Week, Chicago, IL, May 7-10, 2011 [Abstract].
4. Firpo MA, Shea JE, Brown K, Emerson L, Boucher KM, Scaife CL, Mulvihill SJ (2011). Serum MMP-7 is an Independent Predictor of Survival in Patients with Pancreatic Adenocarcinoma. Eleventh Annual Americas Hepato-Pancreato-Biliary Congress, Miami Beach, FL [Abstract]. HPB, 13(Suppl 1), 21.
5. Wallander ML, Layfield LJ, Emerson LL, Mamalis N, Davis D, Holden JA (2011). KIT Mutations in Ocular Melanoma. USCAP, San Antonio, TX, February 26 - March 4, 2011 [Abstract].
6. Poruk KE, Scaife CL, Emerson LL, Boucher KM, Firpo MA, Mulvihill SJ (2010). Serum platelet factor 4 is an independent predictor of survival in patients with pancreatic adenocarcinoma. American Surgical Congress, San Antonio, TX. Feb 3-5, 2010 [Abstract].
7. Naiman N, Kerber R, Emerson L, Goldfarb A, Tang H, Smith L, Ostler D, Mineau G, Schaefer C, Shihab F (2009). A population-based assessment of the familial component of acute kidney allograft rejection [Abstract]. ASN Renal Week, San Diego, CA. October 27- November 1.
8. Shea JE, Emerson LL, Scaife CL (2009). Metastatic tumors express greater levels of pinch [Abstract]. 43rd Annual Pancreas Club Meeting, Chicago, IL. May 30-31.
9. Majer M, Gray P, Li X, Emerson LL, Kuwada SK (2008). Conditional deletion of Erbb2/Neu inhibits pancreatic tumorigenesis [Abstract]. Digestive Disease Week Conference, San Diego, CA. May 17-21.
10. Feng Y, Jeong EK, Emerson L, Lu ZR (2008). Assess tumor acute response to photothermal therapies by DCE-MRI using biodegradable macromolecule contrast agent [Abstract]. International Society of Magnetic Resonance in Medicine 16th Annual Scientific Meeting and Exhibition, Toronto, Ontario. May 3-9.
11. Stafforini DM, Reichert E, Gardner A, Meikle W, Emerson L (2007). Deletion of platelet-activating factor acetylhydrolase (phospholipase A2 Group VII) increases the severity of prostate cancer and reduces life-span in the TRAMP model of prostate carcinogenesis [Abstract]. Department of Defense Prostate Cancer Research Program Meeting, Atlanta, GA. September 5-8.
12. Fang JC, Emerson LL, Hilden K, Thomas KL, Peterson KA (2007). Comparison of esomeprazole to aerosolized, swallowed fluticasone for eosinophilic esophagitis [Abstract]. International Eosinophil Society, 5th Biennial Symposium, Snowbird, Utah. July18-22.
13. Feng Y, Jeong EK, Mohs AM, Emerson L, Lu ZR (2005). Polydisulfide-based biodegradable macromolecular contrast agents for dynamic contrast enhanced MRI: first experience with human prostate cancer xenograft. [Abstract]. International Society of Magnetic Resonance in Medicine 15th Annual Scientific Meeting and Exhibition, Berlin, Germany May 19-25.
14. Goulet CJ, Fang JC, Emerson L, Disario JA (2004). In Vitro Evaluation of Different Modes of Argon Plasma Coagulation in a Porcine Colon [Abstract]. American College of Gastroenterology 69th Annual Scientific Meeting.
15. Jones RG, Peterson KA, Emerson LL (2004). Unusual Gastric Mass [Abstract]. American College of Gastroenterology 69th Annual Scientific Meeting.
16. Rollins MD, Jackson HH, Emerson LL, Mulvihil SJ, Firpo MA, Glasgow RE (2003). Peroxisome proliferator-activated receptor-gamma agonists decrease the severity of acute pancreatitis. Awarded best basic science presentation [Abstract]. American Hepato-Pancreato-Biliary Association 4th America's Congress.

Other

1. Emerson L, Chadwick BE (2008). Cytologic diagnosis of lymphoid lesions of the thyroid gland. Am Soc Clin Pathol Check Sample Series.
2. Layfield L, Emerson L (2002). Spindle Cell Predominant Malignant Neuroepithelial Tumor of Kidney. ARUP Path Elec J.
3. Layfield L, Gopez E, Emerson L (2002). Mediastinal Hemangiolymphangioma: Fine-Needle Aspiration Findings in a Rare Mediastinal Tumor. ARUP Path Elec J.

Huntsman Cancer Institute News

• Researcher Finds Possible Reason for Lung Cancer Driver