Skip to main content
Stephen L. Guthery

Stephen L. Guthery, MD, MS

Languages spoken: English

Clinical Locations

Eccles Primary Children's Outpatient Services Building

801-213-3599

Primary Children's Hospital Outpatient Services at Riverton

801-213-3599
  • Dr. Guthery is the Chief of the Division of Pediatric Gastroenterology, Hepatology, Nutrition at the University of Utah and the Medical Director of Pediatric Gastroenterology at Primary Children's Hospital. His interests include the care of infants, children and adolescents with Crohn's disease, ulcerative colitis and liver disease. His area of research includes the epidemiology, natural history, and genetic basis of childhood-onset ulcerative colitis, Crohn disease, and cholestatic liver diseases. Dr. Guthery is board certified in General Pediatrics, Pediatric Gastroenterology, and Pediatric Transplant Hepatology. Dr. Guthery has served as an expert clinical/scientific consultant for several non-profit agencies and the National Institutes of Health. Dr. Guthery is a native of the Mountain West and has been at the University of Utah and Primary Children’s Hospital for more than 20 years.

    Board Certification

    American Board of Pediatrics (Pediatric Transplant Hepatology)
    American Board of Pediatrics (Pediatrics)
    American Board of Pediatrics (Sub: Pediatric Gastroenterology)
  • Dr. Guthery is the Chief of the Division of Pediatric Gastroenterology, Hepatology, Nutrition at the University of Utah and the Medical Director of Pediatric Gastroenterology at Primary Children's Hospital. His interests include the care of infants, children and adolescents with Crohn's disease, ulcerative colitis and liver disease. His area of research includes the epidemiology, natural history, and genetic basis of childhood-onset ulcerative colitis, Crohn disease, and cholestatic liver diseases. Dr. Guthery is board certified in General Pediatrics, Pediatric Gastroenterology, and Pediatric Transplant Hepatology. Dr. Guthery has served as an expert clinical/scientific consultant for several non-profit agencies and the National Institutes of Health. Dr. Guthery is a native of the Mountain West and has been at the University of Utah and Primary Children’s Hospital for more than 20 years.

    Board Certification and Academic Information

    Academic Departments Pediatrics -Primary
    Human Genetics -Adjunct
    Board Certification
    American Board of Pediatrics (Pediatric Transplant Hepatology)
    American Board of Pediatrics (Pediatrics)
    American Board of Pediatrics (Sub: Pediatric Gastroenterology)

    Education history

    Graduate Training Epidemiology - University of Cincinnati M.Sc.
    Pediatric Gastroenterology, Hepatology, and Nutrition - Cincinnati Children's Hospital Medical Center Fellow
    Residency Pediatrics - Cincinnati Children's Hospital Medical Center Resident
    Medicine - Oregon Health Sciences University M.D.
    Undergraduate Biology - Lewis and Clark College B.A.

    Selected Publications

    Journal Article

    1. Harris RA, Bush AH, Eagar TN, Qian J, Greenwood MP, Opekun AR, Baldassano R, Guthery SL, Noe JD, Otley A, Rosh JR, Kugathasan S, Kellermayer R (2023). Exome Sequencing Implicates DGKZ, ESRRA, and GXYLT1 for Modulating Granuloma Formation in Crohn's Disease. J Pediatr Gastroenterol Nutr.
    2. Bonser D, Malone Jenkins S, Palmquist R, Guthery S, Bonkowsky JL, Jaramillo C (2023). Rapid Genome Sequencing Diagnosis in Pediatric Patients with Liver Dysfunction. J Pediatr, 113534.
    3. Squires JE, Miethke AG, Valencia CA, Hawthorne K, Henn L, Van Hove JLK, Squires RH, Bove K, Horslen S, Kohli R, Molleston JP, Romero R, Alonso EM, Bezerra JA, Guthery SL, Hsu E, Karpen SJ, Loomes KM, Ng VL, Rosenthal P, Mysore K, Wang KS, Friederich MW, Magee JC, Sokol RJ, Childhood Liver Disease Research Network ChiLDReN (2023). Clinical spectrum and genetic causes of mitochondrial hepatopathy phenotype in children. Hepatol Commun, 7(6).
    4. Harpavat S, Hawthorne K, Setchell KDR, Rivas MN, Henn L, Beil CA, Karpen SJ, Ng VL, Alonso EM, Bezerra JA, Guthery SL, Horslen S, Loomes KM, McKiernan P, Magee JC, Merion RM, Molleston JP, Rosenthal P, Thompson RJ, Wang KS, Sokol RJ, Shneider BL, for Childhood Liver Disease Research Network ChiLDReN (2023). Serum bile acids as a prognostic biomarker in biliary atresia following Kasai portoenterostomy. Hepatology, 77(3), 862-873.
    5. Leung DH, Devaraj S, Goodrich NP, Chen X, Rajapakshe D, Ye W, Andreev V, Minard CG, Guffey D, Molleston JP, Bass LM, Karpen SJ, Kamath BM, Wang KS, Sundaram SS, Rosenthal P, McKiernan P, Loomes KM, Jensen MK, Horslen SP, Bezerra JA, Magee JC, Merion RM, Sokol RJ, Shneider BL, Alonso E, Bass L, Kelly S, Riordan M, Melin-Aldana H, Bezerra J, Bove K, Heubi J, Miethke A, Tiao G, Denlinger J, Chapman E, Sokol R, Feldman A, Mack C, Narkewicz M, Suchy F, Sundaram SS, Van Hove J, Garcia B, Kauma M, Kocher K, Steinbeiss M, Lovell M, Loomes KM, Piccoli D, Rand E, Russo P, Spinner N, Erlichman J, Stalford S, Pakstis D, King S, Squires R, Sindhi R, Venkat V, Bukauskas K, McKiernan P, Haberstroh L, Squires J, Rosenthal P, Bull L, Curry J, Langlois C, Kim G, Teckman J, Kociela V, Nagy R, Patel S, Cerkoski J, Molleston JP, Bozic M, Subbarao G, Klipsch A, Sawyers C, Cummings O, Horslen SP, Murray K, Hsu E, Cooper K, Young M, Finn L, Kamath BM, Ng V, Quammie C, Putra J, Sharma D, Parmar A, Guthery S, Jensen K, Rutherford A, Lowichik A, Book L, Meyers R, Hall T, Wang KS, Michail S, Thomas D, Goodhue C, Kohli R, Wang L, Soufi N, Thomas D, Karpen S, Gupta N, Romero R, Vos MB, Tory R, Berauer JP, Abramowsky C, McFall J, Shneider BL, Harpavat S, Hertel P, Leung D, Tessier M, Schady D, Cavallo L, Olvera D, Banks C, Tsai C, Thompson R, Doo E, Hoofnagle J, Sherker A, Torrance R, Hall S, Magee J, Merion R, Spino C, Ye W, Childhood Liver Disease Research Network (2022). Serum biomarkers correlated with liver stiffness assessed in a multicenter study of pediatric cholestatic liver disease. Hepatology, 77(2), 530-545.
    6. Kastenberg ZJ, Deneau MR, OBrien EA, Huynh K, Book LS, Srivastava R, Jensen MK, Jaramillo CM, Guthery SL (2023). Fractionated Bilirubin Among 252,892 Utah Newborns With and Without Biliary Atresia: A 15-year Historical Birth Cohort Study. J Pediatr, 257, 113339.
    7. Gupta N, Lustig RH, Andrews H, Guthery SL, Patel AS, Gokhale R, Goyal A, Siebold L, Sylvester F, Leu CS (2022). Sex-Specific Pathways Lead to Statural Growth Impairment in Children with Crohn's Disease. J Pediatr.
    8. Shneider BL, Kamath BM, Magee JC, Goodrich NP, Loomes KM, Ye W, Spino C, Alonso EM, Molleston JP, Bezerra JA, Wang KS, Karpen SJ, Horslen SP, Guthery SL, Rosenthal P, Squires RH, Sokol RJ, Childhood Liver Disease Research Network ChiLDReN (2022). Use of funded multicenter prospective longitudinal databases to inform clinical trials in rare diseases-Examination of cholestatic liver disease in Alagille syndrome. Hepatol Commun, 6, 1910-1921.
    9. Ruff JC, Zhang Y, Bui DP, Therriault C, Nogee D, Guthery SL, Daniel J (2021). Notes from the Field: Acute Nonviral Hepatitis Linked to a Brand of Alkaline Bottled Water - Clark County, Nevada and California, 2020. MMWR Morb Mortal Wkly Rep, 70(46), 1617-1619.
    10. Short SS, Rollins MD, Zobell S, Torres H, Guthery S (2021). Decreased ER visits and readmission after implementation of a standardized perioperative toolkit for children with IBD. J Pediatr Surg, 57, 604-609.
    11. Gupta N, Lustig RH, Andrews H, Gokhale R, Goyal A, Patel AS, Guthery S, Sylvester F, Siebold L, Leu CS (2020). Clinical Variables Associated With Statural Growth in Pediatric Crohn's Disease Differ by Sex (The Growth Study). Inflamm Bowel Dis, 27(6), 751-759.
    12. El-Matary W, Guthery SL, Amir AZ, DiGuglielmo M, Draijer LG, Furuya KN, Gupta N, Hochberg JT, Horslen S, Kerkar N, Koot BGP, Laborda TJ, Loomes KM, Mack C, Martinez M, Miethke A, Miloh T, Mogul D, Mohammed S, Moroz S, Ovchinsky N, Perito ER, Rao G, Ricciuto A, Sathya P, Schwarz KB, Shah U, Singh R, Soufi N, Valentino PL, Zizzo A, Deneau MR (2020). Colorectal Dysplasia and Cancer in Pediatric-Onset Ulcerative Colitis Associated With Primary Sclerosing Cholangitis. Clin Gastroenterol Hepatol, 19(5), 1067-1070.e2.
    13. Deneau MR, Mack C, Perito ER, Ricciuto A, Valentino PL, Amin M, Amir AZ, Aumar M, Auth M, Broderick A, DiGuglielmo M, Draijer LG, Tavares Fagundes ED, El-Matary W, Ferrari F, Furuya KN, Gupta N, Hochberg JT, Homan M, Horslen S, Iorio R, Jensen MK, Jonas MM, Kamath BM, Kerkar N, Kim KM, Kolho KL, Koot BGP, Laborda TJ, Lee CK, Loomes KM, Martinez M, Miethke A, Miloh T, Mogul D, Mohammad S, Mohan P, Moroz S, Ovchinsky N, Palle S, Papadopoulou A, Rao G, Rodrigues Ferreira A, Sathya P, Schwarz KB, Shah U, Shteyer E, Singh R, Smolka V, Soufi N, Tanaka A, Varier R, Vitola B, Woynarowski M, Zerofsky M, Zizzo A, Guthery SL (2020). The Sclerosing Cholangitis Outcomes in Pediatrics (SCOPE) Index: A Prognostic Tool for Children. Hepatology, 73(3), 1074-1087.
    14. Deneau MR, Mack C, Mogul D, Perito ER, Valentino PL, Amir AZ, DiGuglielmo M, Draijer LG, El-Matary W, Furuya KN, Gupta N, Hochberg JT, Horslen S, Jensen MK, Jonas MM, Kerkar N, Koot BGP, Laborda TJ, Lee CK, Loomes KM, Martinez M, Miethke A, Miloh T, Mohammad S, Ovchinsky N, Rao G, Ricciuto A, Sathya P, Schwarz KB, Shah U, Singh R, Vitola B, Zizzo A, Guthery SL (2020). Oral Vancomycin, Ursodeoxycholic Acid, or No Therapy for Pediatric Primary Sclerosing Cholangitis: A Matched Analysis. Hepatology, 73(3), 1061-1073.
    15. Teckman J, Rosenthal P, Hawthorne K, Spino C, Bass LM, Murray KF, Kerkar N, Magee JC, Karpen S, Heubi JE, Molleston JP, Squires RH, Kamath BM, Guthery SL, Loomes KM, Sherker AH, Sokol RJ, ChiLDReN Childhood Liver Disease Research Network (2020). Longitudinal Outcomes in Young Patients with Alpha-1-Antitrypsin Deficiency with Native Liver Reveal that Neonatal Cholestasis is a Poor Predictor of Future Portal Hypertension. J Pediatr, 227, 81-86.e4.
    16. Gupta N, Lustig RH, Andrews H, Sylvester F, Keljo D, Goyal A, Gokhale R, Patel AS, Guthery S, Leu CS (2019). Introduction to and Screening Visit Results of the Multicenter Pediatric Crohn's Disease Growth Study. Inflamm Bowel Dis, 26(12), 1945-1950.
    17. Taylor MA, West WB, Guthery SL, Deneau M, Short SS (2020). Ketorolac after colectomy for ulcerative colitis in children: An analysis of opioid utilization and postoperative complications. J Pediatr Surg, 55(11), 2393-2396.
    18. McClain A, OGorman M, Barbagelata C, Patel R, Lowichik A, Peterson K, Guthery S, Robson J (2019). Adherence to Biopsy and Follow-Up Guidelines in a Population-Based Cohort of Children With Eosinophilic Esophagitis. Clin Gastroenterol Hepatol, 18(11), 2620-2622.
    19. Haberman Y, Minar P, Karns R, Dexheimer PJ, Ghandikota S, Tegge S, Shapiro D, Shuler B, Venkateswaran S, Braun T, Ta A, Walters TD, Baldassano RN, Noe JD, Rosh J, Markowitz J, Dotson JL, Mack DR, Kellermayer R, Griffiths AM, Heyman MB, Baker SS, Moulton D, Patel AS, Gulati AS, Steiner SJ, LeLeiko N, Otley A, Oliva-Hemker M, Ziring D, Gokhale R, Kim S, Guthery SL, Cohen SA, Snapper S, Aronow BJ, Stephens M, Gibson G, Dillman JR, Dubinsky M, Hyams JS, Kugathasan S, Jegga AG, Denson LA (2020). Mucosal Inflammatory and Wound Healing Gene Programs Reveal Targets for Stricturing Behavior in Pediatric Crohn's Disease. J Crohns Colitis.
    20. Kamath BM, Ye W, Goodrich NP, Loomes KM, Romero R, Heubi JE, Leung DH, Spinner NB, Piccoli DA, Alonso EM, Guthery SL, Karpen SJ, Mack CL, Molleston JP, Murray KF, Rosenthal P, Squires JE, Teckman J, Wang KS, Thompson R, Magee JC, Sokol RJ, Childhood Liver Disease Research Network ChiLDReN (2020). Outcomes of Childhood Cholestasis in Alagille Syndrome: Results of a Multicenter Observational Study. Hepatol Commun, 4(3), 387-398.
    21. Jaramillo C, Guthery SL, Lowichik A, Stoddard G, Kim T, Li Y, Jensen MK (2019). Quantitative Liver Fibrosis Using Collagen Hybridizing Peptide to Predict Native Liver Survival in Biliary Atresia: A Pilot Study. J Pediatr Gastroenterol Nutr, 70(1), 87-92.
    22. Deneau MR, Valentino PL, Mack C, Alqoaer K, Amin M, Amir AZ, Aumar M, Auth M, Broderick A, DiGuglielmo M, Draijer LG, El-Matary W, Ferrari F, Furuya KN, Gottrand F, Gupta N, Homan M, Jensen MK, Kamath BM, Kim KM, Kolho KL, Koot B, Iorio R, Martinez M, Miloh T, Mohan P, Palle S, Papadopoulou A, Ricciuto A, Saubermann L, Sathya P, Shteyer E, Smolka V, Tanaka A, Varier R, Venkat V, Vitola B, Woynarowski M, Guthery S (2019). Assessing the Validity of Adult-derived Prognostic Models for Primary Sclerosing Cholangitis Outcomes in Children. J Pediatr Gastroenterol Nutr, 70(1), e12-e17.
    23. Chen JS, Hu F, Kugathasan S, Jorde LB, Nix D, Rutherford A, Denson L, Watkins WS, Prahalad S, Huff C, Guthery SL (2018). Targeted Gene Sequencing in Children with Crohn's Disease and Their Parents: Implications for Missing Heritability. G3 (Bethesda), 8(9), 2881-2888.
    24. Leiding JW, Okada S, Hagin D, Abinun M, Shcherbina A, Balashov DN, Kim VHD, Ovadia A, Guthery SL, Pulsipher M, Lilic D, Devlin LA, Christie S, Depner M, Fuchs S, van Royen-Kerkhof A, Lindemans C, Petrovic A, Sullivan KE, Bunin N, Kilic SS, Arpaci F, Calle-Martin O, Martinez-Martinez L, Aldave JC, Kobayashi M, Ohkawa T, Imai K, Iguchi A, Roifman CM, Gennery AR, Slatter M, Ochs HD, Morio T, Torgerson TR, Inborn Errors Working Party of the European Society for Blood and Marrow Transplantation and the Primary Immune Deficiency Treatment Consortium (2017). Hematopoietic stem cell transplantation in patients with gain-of-function signal transducer and activator of transcription 1 mutations. J Allergy Clin Immunol, 141(2), 704-717.e5.
    25. Hyams JS, Davis S, Mack DR, Boyle B, Griffiths AM, LeLeiko NS, Sauer CG, Keljo DJ, Markowitz J, Baker SS, Rosh J, Baldassano RN, Patel A, Pfefferkorn M, Otley A, Heyman M, Noe J, Oliva-Hemker M, Rufo P, Strople J, Ziring D, Guthery SL, Sudel B, Benkov K, Wali P, Moulton D, Evans J, Kappelman MD, Marquis A, Sylvester FA, Collins MH, Venkateswaran S, Dubinsky M, Tangpricha V, Spada KL, Britt A, Saul B, Gotman N, Wang J, Serrano J, Kugathasan S, Walters T, Denson LA (2017). Factors associated with early outcomes following standardised therapy in children with ulcerative colitis (PROTECT): a multicentre inception cohort study. Lancet Gastroenterol Hepatol, 2(12), 855-868.
    26. Jewel Samadder N, Valentine JF, Guthery S, Singh H, Bernstein CN, Wan Y, Wong J, Boucher K, Pappas L, Rowe K, Bronner M, Ulrich CM, Burt RW, Curtin K, Smith KR (2017). Colorectal Cancer in Inflammatory Bowel Diseases: A Population-Based Study in Utah. Dig Dis Sci, 62(8), 2126-2132.
    27. Shneider BL, Moore J, Kerkar N, Magee JC, Ye W, Karpen SJ, Kamath BM, Molleston JP, Bezerra JA, Murray KF, Loomes KM, Whitington PF, Rosenthal P, Squires RH, Guthery SL, Arnon R, Schwarz KB, Turmelle YP, Sherker AH, Sokol RJ, Childhood Liver Disease Research Network (2017). Initial assessment of the infant with neonatal cholestasis-Is this biliary atresia? PLoS One, 12(5), e0176275.
    28. Kugathasan S, Denson LA, Walters TD, Kim MO, Marigorta UM, Schirmer M, Mondal K, Liu C, Griffiths A, Noe JD, Crandall WV, Snapper S, Rabizadeh S, Rosh JR, Shapiro JM, Guthery S, Mack DR, Kellermayer R, Kappelman MD, Steiner S, Moulton DE, Keljo D, Cohen S, Oliva-Hemker M, Heyman MB, Otley AR, Baker SS, Evans JS, Kirschner BS, Patel AS, Ziring D, Trapnell BC, Sylvester FA, Stephens MC, Baldassano RN, Markowitz JF, Cho J, Xavier RJ, Huttenhower C, Aronow BJ, Gibson G, Hyams JS, Dubinsky MC (2017). Prediction of complicated disease course for children newly diagnosed with Crohn's disease: a multicentre inception cohort study. Lancet, 389(10080), 1710-1718.
    29. Stittrich AB, Ashworth J, Shi M, Robinson M, Mauldin D, Brunkow ME, Biswas S, Kim JM, Kwon KS, Jung JU, Galas D, Serikawa K, Duerr RH, Guthery SL, Peschon J, Hood L, Roach JC, Glusman G (2016). Genomic architecture of inflammatory bowel disease in five families with multiple affected individuals. Hum Genome Var, 3, 15060.
    30. Lascurain L, Jensen MK, Guthery SL, Holmen J, Deneau M (2016). Inflammatory Bowel Disease Phenotype in Pediatric Primary Sclerosing Cholangitis. Inflamm Bowel Dis, 22(1), 146-50.
    31. Li YR, Zhao SD, Li J, Bradfield JP, Mohebnasab M, Steel L, Kobie J, Abrams DJ, Mentch FD, Glessner JT, Guo Y, Wei Z, Connolly JJ, Cardinale CJ, Bakay M, Li D, Maggadottir SM, Thomas KA, Qui H, Chiavacci RM, Kim CE, Wang F, Snyder J, Flat B, Frre, Denson LA, Thompson SD, Becker ML, Guthery SL, Latiano A, Perez E, Resnick E, Strisciuglio C, Staiano A, Miele E, Silverberg MS, Lie BA, Punaro M, Russell RK, Wilson DC, Dubinsky MC, Monos DS, Annese V, Munro JE, Wise C, Chapel H, Cunningham-Rundles C, Orange JS, Behrens EM, Sullivan KE, Kugathasan S, Griffiths AM, Satsangi J, Grant SFA, Sleiman PMA, Finkel TH, Polychronakos C, Baldassano RN, Luning Prak ET, Ellis JA, Li H, Keating BJ, Hakonarson H (2015). Genetic sharing and heritability of paediatric age of onset autoimmune diseases. Nat Commun, 6, 8442.
    32. Li YR, Li J, Zhao SD, Bradfield JP, Mentch FD, Maggadottir SM, Hou C, Abrams DJ, Chang D, Gao F, Guo Y, Wei Z, Connolly JJ, Cardinale CJ, Bakay M, Glessner JT, Li D, Kao C, Thomas KA, Qiu H, Chiavacci RM, Kim CE, Wang F, Snyder J, Richie MD, Flat B, Frre, Denson LA, Thompson SD, Becker ML, Guthery SL, Latiano A, Perez E, Resnick E, Russell RK, Wilson DC, Silverberg MS, Annese V, Lie BA, Punaro M, Dubinsky MC, Monos DS, Strisciuglio C, Staiano A, Miele E, Kugathasan S, Ellis JA, Munro JE, Sullivan KE, Wise CA, Chapel H, Cunningham-Rundles C, Grant SF, Orange JS, Sleiman PM, Behrens EM, Griffiths AM, Satsangi J, Finkel TH, Keinan A, Prak ET, Polychronakos C, Baldassano RN, Li H, Keating BJ, Hakonarson H (2015). Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases. Nat Med, 21(9), 1018-27.
    33. Cutler DJ, Zwick ME, Okou DT, Prahalad S, Walters T, Guthery SL, Dubinsky M, Baldassano R, Crandall WV, Rosh J, Markowitz J, Stephens M, Kellermayer R, Pfefferkorn M, Heyman MB, LeLeiko N, Mack D, Moulton D, Kappelman MD, Kumar A, Prince J, Bose P, Mondal K, Ramachandran D, Bohnsack JF, Griffiths AM, Haberman Y, Essers J, Thompson SD, Aronow B, Keljo DJ, Hyams JS, Denson LA, PRO-KIIDS Research Group, Kugathasan S (2015). Dissecting Allele Architecture of Early Onset IBD Using High-Density Genotyping. PLoS One, 10(6), e0128074.
    34. Liu R, Cox K, Guthery SL, Book L, Witt B, Chadwick B, Adler DG (2014). Cholangiocarcinoma and high-grade dysplasia in young patients with primary sclerosing cholangitis. Dig Dis Sci, 59(9), 2320-4.
    35. Hu H, Roach JC, Coon H, Guthery SL, Voelkerding KV, Margraf RL, Durtschi JD, Tavtigian SV, Shankaracharya, Wu W, Scheet P, Wang S, Xing J, Glusman G, Hubley R, Li H, Garg V, Moore B, Hood L, Galas DJ, Srivastava D, Reese MG, Jorde LB, Yandell M, Huff CD (2014). A unified test of linkage analysis and rare-variant association for analysis of pedigree sequence data. Nat Biotechnol, 32(7), 663-9.
    36. Singleton MV, Guthery SL, Voelkerding KV, Chen K, Kennedy B, Margraf RL, Durtschi J, Eilbeck K, Reese MG, Jorde LB, Huff CD, Yandell M (2014). Phevor combines multiple biomedical ontologies for accurate identification of disease-causing alleles in single individuals and small nuclear families. Am J Hum Genet, 94(4), 599-610.
    37. Deneau M, Book LS, Guthery SL, Jensen MK (2014). Outcome after discontinuation of immunosuppression in children with autoimmune hepatitis: a population-based study. J Pediatr, 164(4), 714-719.e2.
    38. Walters TD, Kim MO, Denson LA, Griffiths AM, Dubinsky M, Markowitz J, Baldassano R, Crandall W, Rosh J, Pfefferkorn M, Otley A, Heyman MB, LeLeiko N, Baker S, Guthery SL, Evans J, Ziring D, Kellermayer R, Stephens M, Mack D, Oliva-Hemker M, Patel AS, Kirschner B, Moulton D, Cohen S, Kim S, Liu C, Essers J, Kugathasan S, Hyams JS, PRO-KIIDS Research Group (2014). Increased effectiveness of early therapy with anti-tumor necrosis factor-α vs an immunomodulator in children with Crohn's disease. Gastroenterology, 146(2), 383-91.
    39. Li H, Glusman G, Hu H, Shankaracharya, Caballero J, Hubley R, Witherspoon D, Guthery SL, Mauldin DE, Jorde LB, Hood L, Roach JC, Huff CD (2014). Relationship estimation from whole-genome sequence data. PLoS Genet, 10(1), e1004144.
    40. Deneau M, Jensen MK, Holmen J, Williams MS, Book LS, Guthery SL (2013). Primary sclerosing cholangitis, autoimmune hepatitis, and overlap in Utah children: epidemiology and natural history. Hepatology, 58(4), 1392-400.
    41. Hinks A, Cobb J, Marion MC, Prahalad S, Sudman M, Bowes J, Martin P, Comeau ME, Sajuthi S, Andrews R, Brown M, Chen WM, Concannon P, Deloukas P, Edkins S, Eyre S, Gaffney PM, Guthery SL, Guthridge JM, Hunt SE, James JA, Keddache M, Moser KL, Nigrovic PA, Onengut-Gumuscu S, Onslow ML, Ros CD, Rich SS, Steel KJ, Wakeland EK, Wallace CA, Wedderburn LR, Woo P, Boston Childrens JIA Registry, British Society of Paediatric and Adolescent Rheumatology BSPAR Study Group, Childhood Arthritis Prospective Study CAPS, Childhood Arthritis Response to Medication Study CHARMS, German Society for Pediatric Rheumatology GKJR, JIA Gene Expression Study, NIAMS JIA Genetic Registry, TREAT Study, United Kingdom Juvenile Idiopathic Arthritis Genetics Consortium UKJIAGC, Bohnsack JF, Haas JP, Glass DN, Langefeld CD, Thomson W, Thompson SD (2013). Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis. Nat Genet, 45(6), 664-9.
    42. Hinks A, Cobb J, Marion MC, Prahalad S, Sudman M, Bowes J, Martin P, Comeau ME, Sajuthi S, Andrews R, Brown M, Chen WM, Concannon P, Deloukas P, Edkins S, Eyre S, Gaffney PM, Guthery SL, Guthridge JM, Hunt SE, James JA, Keddache M, Moser KL, Nigrovic PA, Onengut-Gumuscu S, Onslow ML, Ros CD, Rich SS, Steel KJ, Wakeland EK, Wallace CA, Wedderburn LR, Woo P, Boston Childrens JIA Registry, British Society of Paediatric and Adolescent Rheumatology BSPAR Study Group, Childhood Arthritis Prospective Study CAPS, Childhood Arthritis Response to Medication Study CHARMS, German Society for Pediatric Rheumatology GKJR, JIA Gene Expression Study, NIAMS JIA Genetic Registry, TREAT Study, United Kingdom Juvenile Idiopathic Arthritis Genetics Consortium UKJIAGC, Bohnsack JF, Haas JP, Glass DN, Langefeld CD, Thomson W, Thompson SD (06/01/2013). Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis. Nat Genet, 45(6), 664-669.
    43. Willson TA, Kuhn BR, Jurickova I, Gerad S, Moon D, Bonkowski E, Carey R, Collins MH, Xu H, Jegga AG, Guthery SL, Denson LA (2011). STAT3 genotypic variation and cellular STAT3 activation and colon leukocyte recruitment in pediatric Crohn disease. J Pediatr Gastroenterol Nutr, 55(1), 32-43.
    44. Huff CD, Witherspoon DJ, Zhang Y, Gatenbee C, Denson LA, Kugathasan S, Hakonarson H, Whiting A, Davis CT, Wu W, Xing J, Watkins WS, Bamshad MJ, Bradfield JP, Bulayeva K, Simonson TS, Jorde LB, Guthery SL (2011). Crohn's disease and genetic hitchhiking at IBD5. Mol Biol Evol, 29(1), 101-11.
    45. Huff CD, Witherspoon DJ, Zhang Y, Gatenbee C, Denson LA, Kugathasan S, Hakonarson H, Whiting A, Davis CT, Wu W, Xing J, Watkins WS, Bamshad MJ, Bradfield JP, Bulayeva K, Simonson TS, Jorde LB, Guthery SL (01/01/2012). Crohn's disease and genetic hitchhiking at IBD5. Mol Biol Evol, 29(1), 101-11.
    46. Deneau M, Adler DG, Schwartz JJ, Hutson W, Sorensen J, Book L, Lowichik A, Guthery S (2011). Cholangiocarcinoma in a 17-year-old boy with primary sclerosing cholangitis and inflammatory bowel disease. J Pediatr Gastroenterol Nutr, 52(5), 617-20.
    47. Huff CD, Witherspoon DJ, Simonson TS, Xing J, Watkins WS, Zhang Y, Tuohy TM, Neklason DW, Burt RW, Guthery SL, Woodward SR, Jorde LB (2011). Maximum-likelihood estimation of recent shared ancestry (ERSA). Genome Res, 21(5), 768-74.
    48. Anderson CA, Boucher G, Lees CW, Franke A, DAmato M, Taylor KD, Lee JC, Goyette P, Imielinski M, Latiano A, Lagac C, Scott R, Amininejad L, Bumpstead S, Baidoo L, Baldassano RN, Barclay M, Bayless TM, Brand S, Bning C, Colombel JF, Denson LA, De Vos M, Dubinsky M, Edwards C, Ellinghaus D, Fehrmann RS, Floyd JA, Florin T, Franchimont D, Franke L, Georges M, Glas J, Glazer NL, Guthery SL, Haritunians T, Hayward NK, Hugot JP, Jobin G, Laukens D, Lawrance I, Lmann M, Levine A, Libioulle C, Louis E, McGovern DP, Milla M, Montgomery GW, Morley KI, Mowat C, Ng A, Newman W, Ophoff RA, Papi L, Palmieri O, Peyrin-Biroulet L, Pans J, Phillips A, Prescott NJ, Proctor DD, Roberts R, Russell R, Rutgeerts P, Sanderson J, Sans M, Schumm P, Seibold F, Sharma Y, Simms LA, Seielstad M, Steinhart AH, Targan SR, van den Berg LH, Vatn M, Verspaget H, Walters T, Wijmenga C, Wilson DC, Westra HJ, Xavier RJ, Zhao ZZ, Ponsioen CY, Andersen V, Torkvist L, Gazouli M, Anagnou NP, Karlsen TH, Kupcinskas L, Sventoraityte J, Mansfield JC, Kugathasan S, Silverberg MS, Halfvarson J, Rotter JI, Mathew CG, Griffiths AM, Gearry R, Ahmad T, Brant SR, Chamaillard M, Satsangi J, Cho JH, Schreiber S, Daly MJ, Barrett JC, Parkes M, Annese V, Hakonarson H, Radford-Smith G, Duerr RH, Vermeire S, Weersma RK, Rioux JD (2011). Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47. Nat Genet, 43(3), 246-52.
    49. Guthery SL, Mineau G, Pimentel R, Williams MS, Kerber RA (2011). Inflammatory bowel disease aggregation in Utah kindreds. Inflamm Bowel Dis, 17(3), 823-30.
    50. Moore JC, Thompson K, Lafleur B, Book LS, Jackson WD, OGorman MA, Black RE, Downey E Jr, Johnson DG, Matlak ME, Meyers RL, Scaife E, Guthery SL (2011). Clinical variables as prognostic tools in pediatric-onset ulcerative colitis: a retrospective cohort study. Inflamm Bowel Dis, 17(1), 15-21.
    51. Franke A, McGovern DP, Barrett JC, Wang K, Radford-Smith GL, Ahmad T, Lees CW, Balschun T, Lee J, Roberts R, Anderson CA, Bis JC, Bumpstead S, Ellinghaus D, Festen EM, Georges M, Green T, Haritunians T, Jostins L, Latiano A, Mathew CG, Montgomery GW, Prescott NJ, Raychaudhuri S, Rotter JI, Schumm P, Sharma Y, Simms LA, Taylor KD, Whiteman D, Wijmenga C, Baldassano RN, Barclay M, Bayless TM, Brand S, Bning C, Cohen A, Colombel JF, Cottone M, Stronati L, Denson T, De Vos M, DInca R, Dubinsky M, Edwards C, Florin T, Franchimont D, Gearry R, Glas J, Van Gossum A, Guthery SL, Halfvarson J, Verspaget HW, Hugot JP, Karban A, Laukens D, Lawrance I, Lemann M, Levine A, Libioulle C, Louis E, Mowat C, Newman W, Pans J, Phillips A, Proctor DD, Regueiro M, Russell R, Rutgeerts P, Sanderson J, Sans M, Seibold F, Steinhart AH, Stokkers PC, Torkvist L, Kullak-Ublick G, Wilson D, Walters T, Targan SR, Brant SR, Rioux JD, DAmato M, Weersma RK, Kugathasan S, Griffiths AM, Mansfield JC, Vermeire S, Duerr RH, Silverberg MS, Satsangi J, Schreiber S, Cho JH, Annese V, Hakonarson H, Daly MJ, Parkes M (2010). Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci. Nat Genet, 42(12), 1118-25.
    52. Imielinski M, Baldassano RN, Griffiths A, Russell RK, Annese V, Dubinsky M, Kugathasan S, Bradfield JP, Walters TD, Sleiman P, Kim CE, Muise A, Wang K, Glessner JT, Saeed S, Zhang H, Frackelton EC, Hou C, Flory JH, Otieno G, Chiavacci RM, Grundmeier R, Castro M, Latiano A, Dallapiccola B, Stempak J, Abrams DJ, Taylor K, McGovern D, Western Regional Alliance for Pediatric IBD, Silber G, Wrobel I, Quiros A, International IBD Genetics Consortium, Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmuda MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, Schumm LP, Steinhart AH, Targan SR, Xavier RJ, NIDDK IBD Genetics Consortium, Libioulle C, Sandor C, Lathrop M, Belaiche J, Dewit O, Gut I, Heath S, Laukens D, Mni M, Rutgeerts P, Van Gossum A, Zelenika D, Franchimont D, Hugot JP, de Vos M, Vermeire S, Louis E, Belgian-French IBD Consortium, Wellcome Trust Case Control Consortium, Cardon LR, Anderson CA, Drummond H, Nimmo E, Ahmad T, Prescott NJ, Onnie CM, Fisher SA, Marchini J, Ghori J, Bumpstead S, Gwillam R, Tremelling M, Delukas P, Mansfield J, Jewell D, Satsangi J, Mathew CG, Parkes M, Georges M, Daly MJ, Heyman MB, Ferry GD, Kirschner B, Lee J, Essers J, Grand R, Stephens M, Levine A, Piccoli D, Van Limbergen J, Cucchiara S, Monos DS, Guthery SL, Denson L, Wilson DC, Grant SF, Daly M, Silverberg MS, Satsangi J, Hakonarson H (2009). Common variants at five new loci associated with early-onset inflammatory bowel disease. Nat Genet, 41(12), 1335-40.
    53. Xing J, Watkins WS, Witherspoon DJ, Zhang Y, Guthery SL, Thara R, Mowry BJ, Bulayeva K, Weiss RB, Jorde LB (2009). Fine-scaled human genetic structure revealed by SNP microarrays. Genome Res, 19(5), 815-25.
    54. Nair RP, Duffin KC, Helms C, Ding J, Stuart PE, Goldgar D, Gudjonsson JE, Li Y, Tejasvi T, Feng BJ, Ruether A, Schreiber S, Weichenthal M, Gladman D, Rahman P, Schrodi SJ, Prahalad S, Guthery SL, Fischer J, Liao W, Kwok PY, Menter A, Lathrop GM, Wise CA, Begovich AB, Voorhees JJ, Elder JT, Krueger GG, Bowcock AM, Abecasis GR, Collaborative Association Study of Psoriasis (2009). Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. Nat Genet, 41(2), 199-204.
    55. Kugathasan S, Baldassano RN, Bradfield JP, Sleiman PM, Imielinski M, Guthery SL, Cucchiara S, Kim CE, Frackelton EC, Annaiah K, Glessner JT, Santa E, Willson T, Eckert AW, Bonkowski E, Shaner JL, Smith RM, Otieno FG, Peterson N, Abrams DJ, Chiavacci RM, Grundmeier R, Mamula P, Tomer G, Piccoli DA, Monos DS, Annese V, Denson LA, Grant SF, Hakonarson H (2008). Loci on 20q13 and 21q22 are associated with pediatric-onset inflammatory bowel disease. Nat Genet, 40(10), 1211-5.
    56. Bamshad M, Guthery SL (2007). Race, genetics and medicine: does the color of a leopard's spots matter? Curr Opin Pediatr, 19(6), 613-8.
    57. Guthery SL, Salisbury BA, Pungliya MS, Stephens JC, Bamshad M (2007). The structure of common genetic variation in United States populations. Am J Hum Genet, 81(6), 1221-31.
    58. Guthery SL, Heubi JE, Filipovich A (2004). Enteral metronidazole for the prevention of graft versus host disease in pediatric marrow transplant recipients: results of a pilot study. Bone Marrow Transplant, 33(12), 1235-9.
    59. Guthery SL, Hutchings C, Dean JM, Hoff C (2004). National estimates of hospital utilization by children with gastrointestinal disorders: analysis of the 1997 kids' inpatient database. J Pediatr, 144(5), 589-94.
    60. Guthery SL, Heubi JE, Bucuvalas JC, Gross TG, Ryckman FC, Alonso MH, Balistreri WF, Hornung RW (2003). Determination of risk factors for Epstein-Barr virus-associated posttransplant lymphoproliferative disorder in pediatric liver transplant recipients using objective case ascertainment. Transplantation, 75(7), 987-93.
    61. Guthery SL, Pohl JF, Bucuvalas JC, Alonso MH, Ryckman FC, Balistreri WF, Heubi JE (2003). Bone mineral density in long-term survivors following pediatric liver transplantation. Liver Transpl, 9(4), 365-70.
    62. Guthery SL, Heubi JE (2001). Liver involvement in childhood histiocytic syndromes. Curr Opin Gastroenterol, 17(5), 474-8.

    Review

    1. Rabbani T, Guthery SL, Himes R, Shneider BL, Harpavat S (2021). Newborn Screening for Biliary Atresia: a Review of Current Methods. [Review]. Curr Gastroenterol Rep, 23(12), 28.

    Letter

    1. Peterson N, Guthery S, Denson L, Lee J, Saeed S, Prahalad S, Biank V, Ehlert R, Tomer G, Grand R, Rudolph C, Kugathasan S (2008). Genetic variants in the autophagy pathway contribute to paediatric Crohn's disease. [Letter to the editor]. Gut, 57(9), 1336-7; author reply 1337.