
Languages Spoken: English, Hindi
My clinical service responsibilities are in hematopathology, where I sign out molecular hematopathology, lymph node/bone marrow cases and flow cytometric evaluation for blood related disorders. My other clinical service responsibilities are in the Red Blood Cell Laboratory/Special Genetics Laboratory at ARUP, where I am the Co Medical Director. In this capacity, I am involved in review of patient test results, case sign out, review of quality control and quality assurance data, proficiency testing, and other clinical and administrative laboratory-related activities. I also provide consultation with clinical colleagues both locally and nationally in the area of hemoglobinopathies. My goal is to provide physicians with high quality test results and to give them my consultative expertise. In the area of teaching, I act as the director for the hemoglobinopathy/ thalassemia and benign red blood cell disorders rotation for hematopathology fellows.
Specialties
Board Certification and Academic Information
Academic Departments | Pathology
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Professor (Clinical) |
Academic Divisions | Clinical Pathology |
Board Certification | American Board of Pathology (Clinical Path) American Board of Pathology (Sub: Anatomic Path) American Board of Pathology (Sub: Hematology) American Board of Pathology (Sub: Molecular Genetic Pathology) National Board of Medical Examiners |
My clinical service responsibilities are in hematopathology, where I sign out molecular hematopathology, lymph node/bone marrow cases and flow cytometric evaluation for blood related disorders. My other clinical service responsibilities are in the Red Blood Cell Laboratory/Special Genetics Laboratory at ARUP, where I am the Co Medical Director. In this capacity, I am involved in review of patient test results, case sign out, review of quality control and quality assurance data, proficiency testing, and other clinical and administrative laboratory-related activities. I also provide consultation with clinical colleagues both locally and nationally in the area of hemoglobinopathies. My goal is to provide physicians with high quality test results and to give them my consultative expertise. In the area of teaching, I act as the director for the hemoglobinopathy/ thalassemia and benign red blood cell disorders rotation for hematopathology fellows.
Academic Locations
Board Certification and Academic Information
Academic Departments | Pathology
-
Professor (Clinical) |
Academic Divisions | Clinical Pathology |
Board Certification | American Board of Pathology (Clinical Path) American Board of Pathology (Sub: Anatomic Path) American Board of Pathology (Sub: Hematology) American Board of Pathology (Sub: Molecular Genetic Pathology) National Board of Medical Examiners |
Education History
Fellowship | University of Utah School of Medicine, Department of Pathology Molecular Genetic Pathology Fellow, 2010 |
Residency | University of Utah School of Medicine, Department of Pathology Anatomic and Clinical Resident, 2009 |
Fellowship | University of Utah School of Medicine Hematopathology Fellow, 2008 |
Residency | University of Utah School of Medicine, Department of Pathology Anatomic and Clinical Resident, 2007 |
Postdoctoral Fellowship | University of Iowa Research Scholar Postdoctoral Fellow, 2004 |
Professional Medical | Delhi University Pathology M.D., 2001 |
Professional Medical | Assam Medical College Medicine M.B.B.S., 1995 |
Selected Publications - Journal Articles
Journal Article
- Lin Y, Agarwal AM, Marshall AG, Anderson LC (2021). Characterization of Structural Hemoglobin Variants by Top-Down Mass Spectrometry and R Programming Tools for Rapid Identification. J Am Soc Mass Spectrom, 33(1), 123-130.
- Meznarich JA, Rets A, Agarwal AM, Christensen RD, Reading NS, Kuypers FA, Prchal JT (2021). Novel, de novo, beta-globin variant with decreased oxygen affinity (HBB:c.317T>A, "Hemoglobin St. George") in a healthy child with low oxygen saturations and anemia. Am J Hematol, 96(12), E448-E450.
- Bahr TM, Agarwal AM, Meznarich JA, Prince WL, Wait TWP, Prchal JT, Christensen RD (2021). Thirty-five males with severe (Class 1) G6PD deficiency (c.637G>T) in a North American family of European ancestry. Blood Cells Mol Dis, 92, 102625.
- Bahr TM, Agarwal AM, Christensen RD (2020). Does heterozygosity for UGT1A1 *28 convey increased risk for severe neonatal jaundice? J Perinatol, 41(4), 658-660.
- Lozano-Chinga M, Draper L, George TI, Agarwal AM, Dansie DM, Maese L (2020). Bone marrow necrosis in pediatric malignancies: 10-Year retrospective review and review of literature. Pediatr Blood Cancer, 68(3), e28806.
- Kim SJ, Song J, Reading NS, Lautersztain J, Kutlar A, Agarwal AM, Coetzer TL, Prchal JT (2021). Novel Mechanism of Hereditary Pyropoikilocytosis Phenotype due to Co-inheritance of β Globin and α Spectrin Mutations. Am J Hematol, 96(5), Epub 2021 Feb 25.
- Iglesias Cardenas F, Agarwal AM, Vagher J, Maese L, Fluchel M, Afify Z (2021). Two Clonally Distinct B-Cell Lymphomas Reveal the Diagnosis of XLP1 in a Male Child and His Asymptomatic Male Relatives: Case Report and Review of the Literature. J Pediatr Hematol Oncol, 43(8), e1210-e1213.
- Bahr TM, Lozano-Chinga M, Agarwal AM, Meznarich JA, Gerday E, Smoot JL, Taylor A, Christensen RD (2020). Dizygotic twins with prolonged jaundice and microcytic, hypochromic, hemolytic anemia with pyropoikilocytosis. Blood Cells Mol Dis, 85, 102462.
- Rets AV, Reading NS, Agarwal AM (2020). δ-Globin Chain Variants Associated with Decreased Hb A2 Levels: A National Reference Laboratory Experience. Hemoglobin, 44(6), 438-441.
- Cowman SJ, Fuja DG, Liu XD, Tidwell RSS, Kandula N, Sirohi D, Agarwal AM, Emerson LL, Tripp SR, Mohlman JS, Stonhill M, Garcia G, Conley CJ, Olalde AA, Sargis T, Ramirez-Torres A, Karam JA, Wood CG, Sircar K, Tamboli P, Boucher K, Maughan B, Spike BT, Ho TH, Agarwal N, Jonasch E, Koh MY (2020). Macrophage HIF-1α Is an Independent Prognostic Indicator in Kidney Cancer. Clin Cancer Res, 26(18), 4970-4982.
- Agarwal AM, Rets A (2020). Laboratory approach to investigation of anemia with a focus on pyruvate kinase deficiency. Int J Lab Hematol, 42 Suppl 1, 107-112.
- Samha L, Sirdah MM, Reading NS, Karmi B, Agarwal AM (2020). Molecular Understanding of Severe Cases of β-Thalassemia in the Nablus Region, West Bank, Palestine. Hemoglobin, 44(2), 128-130.
- He L, Rockwood AL, Agarwal AM, Anderson LC, Weisbrod CR, Hendrickson CL, Marshall AG (2020). Top-down proteomics-a near-future technique for clinical diagnosis? Ann Transl Med, 8(4), 136.
- Patel AB, Franzini A, Leroy E, Kim SJ, Pomicter AD, Genet L, Xiao M, Yan D, Ahmann JM, Agarwal AM, Clair P, Addada J, Lambert J, Salmon M, Gleich GJ, Cross NCP, Constantinescu SN, OHare T, Prchal JT, Deininger MW (2019). JAK2 ex13InDel drives oncogenic transformation and is associated with chronic eosinophilic leukemia and polycythemia vera. Blood, 134(26), 2388-2398.
- Bianchi P, Fermo E, Glader B, Kanno H, Agarwal A, Barcellini W, Eber S, Hoyer JD, Kuter DJ, Maia TM, Mau-Pereira MDM, Kalfa TA, Pissard S, Segovia JC, van Beers E, Gallagher PG, Rees DC, van Wijk R, with the endorsement of EuroBloodNet, the European Reference Network in Rare Hematological, Diseases (2019). Addressing the diagnostic gaps in pyruvate kinase deficiency: Consensus recommendations on the diagnosis of pyruvate kinase deficiency. Am J Hematol, 94(1), 149-161.
- He L, Rockwood AL, Agarwal AM, Anderson LC, Weisbrod CR, Hendrickson CL, Marshall AG (2019). Diagnosis of Hemoglobinopathy and β-Thalassemia by 21 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometry and Tandem Mass Spectrometry of Hemoglobin from Blood. Clin Chem, 65(8), 986-994.
- Rets A, Clayton AL, Christensen RD, Agarwal AM (2019). Molecular diagnostic update in hereditary hemolytic anemia and neonatal hyperbilirubinemia. Int J Lab Hematol, 41 Suppl 1, 95-101.
- Stenehjem DD, Hahn AW, Gill DM, Albertson D, Gowrishankar B, Merriman J, Agarwal AM, Thodima V, Harrington EB, Au TH, Maughan BL, Houldsworth J, Pal SK, Agarwal N (2019). Predictive genomic markers of response to VEGF targeted therapy in metastatic renal cell carcinoma. PLoS One, 14(1), e0210415.
- Bahr TM, Christensen RD, Agarwal AM, George TI, Bhutani VK (2019). The Neonatal Acute Bilirubin Encephalopathy Registry (NABER): Background, Aims, and Protocol. Neonatology, 115(3), 242-246.
- Christensen RD, Agarwal AM, George TI, Bhutani VK, Yaish HM (2018). Acute neonatal bilirubin encephalopathy in the State of Utah 2009-2018. Blood Cells Mol Dis, 72, 10-13.
- Hahn AW, Gill DM, Maughan B, Agarwal A, Arjyal L, Gupta S, Streeter J, Bailey E, Pal SK, Agarwal N (2017). Correlation of genomic alterations assessed by next-generation sequencing (NGS) of tumor tissue DNA and circulating tumor DNA (ctDNA) in metastatic renal cell carcinoma (mRCC): potential clinical implications. Oncotarget, 8(20), 33614-33620.
- Luedeke M, Rinckleb AE, FitzGerald LM, Geybels MS, Schleutker J, Eeles RA, Teixeira MR, Cannon-Albright L, Ostrander EA, Weikert S, Herkommer K, Wahlfors T, Visakorpi T, Leinonen KA, Tammela TLJ, Cooper CS, Kote-Jarai Z, Edwards S, Goh CL, McCarthy F, Parker C, Flohr P, Paulo P, Jernimo C, Henrique R, Krause H, Wach S, Lieb V, Rau TT, Vogel W, Kuefer R, Hofer MD, Perner S, Rubin MA, Agarwal AM, Easton DF, Al Olama AA, Benlloch S, PRACTICAL consortium, Hoegel J, Stanford JL, Maier C (2016). Prostate cancer risk regions at 8q24 and 17q24 are differentially associated with somatic TMPRSS2:ERG fusion status. Hum Mol Genet, 25(24), 5490-5499.
- Agarwal AM, Liew MA, Nussenzveig RH, Sangle N, Heikal N, Yaish H, Christensen R (2015). Improved harmonization of eosin-5-maleimide binding test across different instruments and age groups. Cytometry B Clin Cytom, 90(6), 512-516.
- Reading NS, Shooter C, Song J, Miller R, Agarwal A, Lanikova L, Clark B, Thein SL, Divoky V, Prchal JT (2016). Loss of Major DNase I Hypersensitive Sites in Duplicated β-globin Gene Cluster Incompletely Silences HBB Gene Expression. Hum Mutat, 37(11), 1153-1156.
- Tantravahi SK, Albertson D, Agarwal AM, Ravulapati S, Poole A, Patel SB, Hawatmeh JS, Straubhar AM, Liu T, Stenehjem DD, Agarwal N (2015). Survival Outcomes and Tumor IMP3 Expression in Patients with Sarcomatoid Metastatic Renal Cell Carcinoma. J Oncol, 2015, 181926.
- Swierczek S, Agarwal AM, Naidoo K, Lorenzo FR, Whisenant J, Nussenzveig RH, Agarwal N, Coetzer TL, Prchal JT (2013). Novel exon 2 α spectrin mutation and intragenic crossover: three morphological phenotypes associated with four distinct α spectrin defects. Haematologica, 98(12), 1972-9.
- Yaish HM, Christensen RD, Agarwal A (2013). A neonate with Coombs-negative hemolytic jaundice with spherocytes but normal erythrocyte indices: a rare case of autosomal-recessive hereditary spherocytosis due to alpha-spectrin deficiency. J Perinatol, 33(5), 404-6.
- Patel JC, Maughan BL, Agarwal AM, Batten JA, Zhang TY, Agarwal N (2013). Emerging molecularly targeted therapies in castration refractory prostate cancer. Prostate Cancer, 2013, 981684.
- Nussenzveig RH, Burjanivova T, Salama ME, Ogilvie NW, Marcinek J, Plank L, Agarwal AM, Perkins SL, Prchal JT (2012). Detection of JAK2 mutations in paraffin marrow biopsies by high resolution melting analysis: identification of L611S alone and in cis with V617F in polycythemia vera. Leuk Lymphoma, 53(12), 2479-86.
- Vanhille DL, Nussenzveig RH, Glezos C, Perkins S, Agarwal AM (2012). Best practices for use of the HEMOX analyzer in the clinical laboratory: quality control determination and choice of anticoagulant. Lab Hematol, 18(3), 17-9.
- Sangle NA, Agarwal AM, Smock KJ, Leavitt MO, Warnke R, Bahler D, Perkins SL (2011). Diffuse large B-cell lymphoma with aberrant expression of the T-cell antigens CD2 and CD7. Appl Immunohistochem Mol Morphol, 19(6), 579-83.
- Agarwal AM, Grey TC (2009). Pulmonary talc granulomatosis masquerading as massive pulmonary embolism. Int J Surg Pathol, 17(6), 454.
Review
Book Chapter
- Sherrie L Perkins, Mohamed E Salama, Archana M Agarwal (In Press). Contributor: Case Studies in Hematology and Coagulation. In Gene L Gulati; Joanne Filicko-O'Hara; John R Krause (Ed.) (2nd). ASCP caseset.
- Agarwal AM, Rodgers G (2018). Miscellaneous causes of thrombocytopenia. In Greer JP, Foerrster J, Rodgers G, Paraskevas F, Glader B, Arber D, (Eds.), Wintrobe Hematolog (14). .Lippincott Williams & Wilkins.
Case Report
- Maglic D, Moss W, Pires G, Agarwal A, Matsen C, Kwok A (2021). A Case Report of Misdiagnosed Breast Implant-associated Anaplastic Large Cell Lymphoma with Lymphatic Extension. Plast Reconstr Surg Glob Open, 9(11), e3916.
- Bahr TM, Knudsen MC, Lozano-Chinga M, Agarwal AM, Meznarich JA, Ohls RK, Christensen RD (2020). Infantile Pyknocytosis: End-Tidal CO, %Micro-R Measurements, Next-Generation Sequencing, and Transfusion Avoidance with Darbepoetin. Biomed Hub, 5(3), 227-234.
- Agarwal AM, Hanley T (2020). Osteopetrosis in a six-month-old infant. J Hematop, 13, 193–196.
- Bahr TM, Lozano-Chinga M, Agarwal AM, Meznarich JA, Yost CC, Li P, Reading NS, Prchal JT, Christensen RD (2020). A Novel Variant in G6PD (c.1375C>G) Identified from a Hispanic Neonate with Extreme Hyperbilirubinemia and Low G6PD Enzymatic Activity. Neonatology, 117(4), 532-535.
Editorial
Abstract
- Nussenzveig RH, Sangle N, Christensen RD, Salama ME, Prchal J, Yaish H, Agarwal AM (2013). Clinical Utility of Next-Generation Sequencing In the Diagnosis of Hereditary Hemolytic Anemias [Abstract]. Blood, 122, 3421.
- Nussenzveig RH, Salama ME, Perkins SL, Prchal J, Agarwal AM (2013). Clinical Utility of Next-Generation Sequencing In the diagnosis of Polycythemia. [Abstract]. Blood, 122, 2185.
- Agarwal N, Swierczek S, Lorenzo FR, Naidoo K, Agarwal AM, Nussenzveig RH, Whisenant J, Coetzer TL, Prchal JT (2008). Novel exon 2 alpha spectrin mutation in a Caucasian family with pyropoikilocytosis, elliptocytosis, and normal morphology: three phenotypes due to decreased spectrin mRNA and intragenic crossover [Abstract]. Blood, 112, 3840.
- Ferrando A, Palomero T, Sulis ML, Cortina M, Real PJ, Barnes K, Ciofani M, Caparros E, Perkins SL, Bhagat G, Mishra A, Basso G, Parsons R, Zniga-Pflcker CJ, Dominguez M (2007). Mutational Loss of PTEN Induces Resistance to NOTCH1 Inhibition in T-ALL. Plenary Session Presentation, American Society of Hematology Annual Meeting. [Abstract ]. [Abstract]. Blood, 110.
- Bruchova H, Yoon D, Agarwal AM, Otahalova E, Kim H, Prchal JT (2007). Erythropoiesis in Polycythemia Vera Is Hyper-proliferative and Has Accelerated Differentiation during In Vitro Erythroid Expansion and Is Associated with Higher Expressions of cMYB and EPOR at Early Erythroid Progenitors. Poster Presentation, American Society of Hematology, Annual Meeting. [Abstract]. [Abstract]. Blood, 110, 1549.
- Yoon D, Bruchova H, Agarwal AM, Prchal JT, Prchal JF (2006). In Vitro Erythroid Cell Expansion Analysis in Polycythemia Vera. Publication only. American Society of Hematology, Annual Meeting. [Abstract]. [Abstract]. 108, 4916.
Global Impact
Education History
Professional Medical | Delhi University Pathology M.D. |
Professional Medical | Assam Medical College Medicine M.B.B.S. |