Nicholas Shawn Whipple,
MD, MPH
Languages Spoken: English, Spanish
Nicholas Whipple, MD, MPH, received his medical degree from the University of Mississippi School of Medicine in Jackson, MS. After completing his pediatric residency at the University of Utah and Primary Children's Hospital in Salt Lake City, UT, Dr. Whipple completed 3 years of fellowship training in Pediatric Hematology-Oncology and 1 year of Fellowship training in Pediatric Neuro-Oncology at St. Jude Children’s Research Hospital in Memphis, TN. During fellowship training, Dr. Whipple also earned a Master of Public Health (MPH) degree at the Milken Institute School of Public Health at George Washington University. Dr. Whipple joined the faculty of the University of Utah in 2017, where he is currently an Assistant Professor of Pediatrics in the Division of Pediatric Hematology and Oncology. He serves as the Medical Director of Pediatric Neuro-Oncology at Primary Children’s Hospital and the University of Utah. He also serves as the Principal Investigator for the Pacific Pediatric Neuro-Oncology Consortium (PNOC) in Utah (1 of 18 sites in the nation), where he oversees all PNOC clinical trials in Utah. Dr. Whipple’s clinical focus is in pediatric neuro-oncology, histiocytic disorders, and rare tumors. He has authored several publications and book chapters on a variety of topics in both pediatric hematology and oncology. His research primarily focuses on pediatric neuro-oncology, hereditary cancer syndromes, and improving the treatment of children with central nervous system tumors using molecularly targeted therapies. He is currently working to develop early phase clinical trials for children with recurrent malignant central nervous tumors. Dr. Whipple is board certified in both Pediatrics and Pediatric Hematology-Oncology.
Clinical Locations
Primary Children's Hospital
Pediatric Hematology/Oncology801-662-4700
Specialties
Board Certification and Academic Information
| Academic Departments | Pediatrics
-
Associate Professor (Clinical) |
| Academic Divisions | Pediatric Hematology/Oncology |
| Board Certification | American Board of Pediatrics (Pediatrics) American Board of Pediatrics (Sub: Pediatric Hematology-Oncology) |
Nicholas Whipple, MD, MPH, received his medical degree from the University of Mississippi School of Medicine in Jackson, MS. After completing his pediatric residency at the University of Utah and Primary Children's Hospital in Salt Lake City, UT, Dr. Whipple completed 3 years of fellowship training in Pediatric Hematology-Oncology and 1 year of Fellowship training in Pediatric Neuro-Oncology at St. Jude Children’s Research Hospital in Memphis, TN. During fellowship training, Dr. Whipple also earned a Master of Public Health (MPH) degree at the Milken Institute School of Public Health at George Washington University. Dr. Whipple joined the faculty of the University of Utah in 2017, where he is currently an Assistant Professor of Pediatrics in the Division of Pediatric Hematology and Oncology. He serves as the Medical Director of Pediatric Neuro-Oncology at Primary Children’s Hospital and the University of Utah. He also serves as the Principal Investigator for the Pacific Pediatric Neuro-Oncology Consortium (PNOC) in Utah (1 of 18 sites in the nation), where he oversees all PNOC clinical trials in Utah. Dr. Whipple’s clinical focus is in pediatric neuro-oncology, histiocytic disorders, and rare tumors. He has authored several publications and book chapters on a variety of topics in both pediatric hematology and oncology. His research primarily focuses on pediatric neuro-oncology, hereditary cancer syndromes, and improving the treatment of children with central nervous system tumors using molecularly targeted therapies. He is currently working to develop early phase clinical trials for children with recurrent malignant central nervous tumors. Dr. Whipple is board certified in both Pediatrics and Pediatric Hematology-Oncology.
Academic Locations
Board Certification and Academic Information
| Academic Departments | Pediatrics
-
Associate Professor (Clinical) |
| Academic Divisions | Pediatric Hematology/Oncology |
| Board Certification | American Board of Pediatrics (Pediatrics) American Board of Pediatrics (Sub: Pediatric Hematology-Oncology) |
Education History
| Fellowship | St. Jude Children’s Research Hospital Pediatric Neuro-Oncology Fellow, 2017 |
| Graduate Training | George Washington University Emphasis: Epidemiology and Global Health M.P.H., 2016 |
| Fellowship | St. Jude Children’s Research Hospital Pediatric Hematology/Oncology Fellow, 2016 |
| Residency | University of Utah School of Medicine Pediatrics Resident, 2013 |
| Professional Medical | University of Mississippi School of Medicine Medicine M.D., 2010 |
| Undergraduate | University of Mississippi English B.A., 2006 |
| Undergraduate | Northeast Mississippi Community College Biological and Physical Sciences A.A., 2004 |
Selected Publications - Journal Articles
Journal Article
- Lucas CG, Abdullaev Z, Bruggers CS, Mirchia K, Whipple NS, Alashari MM, Lowichik A, Cheshier S, Phillips JJ, Devine P, Solomon DA, Quezado M, Aldape KD, Perry A (2021). Activating NTRK2 and ALK receptor tyrosine kinase fusions extend the molecular spectrum of pleomorphic xanthoastrocytomas of early childhood: a diagnostic overlap with infant-type hemispheric glioma. Acta Neuropathol, 143(2), 283-286.
- Johnston EE, Martinez I, Davis ES, Caudill C, Richman J, Brackett J, Dickens DS, Kahn A, Schwalm C, Sharma A, Patel PA, Bhatia S, Levine JM, Wolfson JA, POCC Consortium (2021). SARS-CoV-2 in Childhood Cancer in 2020: A Disease of Disparities. (Whipple, NS, Member of POCC Consortium). J Clin Oncol, 39(34), 3778-3788.
- Mukkada S, Bhakta N, Chantada GL, Chen Y, Vedaraju Y, Faughnan L, Homsi MR, Muniz-Talavera H, Ranadive R, Metzger M, Friedrich P, Agulnik A, Jeha S, Lam C, Dalvi R, Hessissen L, Moreira DC, Santana VM, Sullivan M, Bouffet E, Caniza MA, Devidas M, Pritchard-Jones K, Rodriguez-Galindo C, Global Registry of COVID-19 in Childhood Cancer (2021). Global characteristics and outcomes of SARS-CoV-2 infection in children and adolescents with cancer (GRCCC): a cohort study. Lancet Oncol, 22(10), 1416-1426.
- Whipple NS, Joshi VM, Naik RJ, Mentnech T, McFarland MM, Nolan VG, Hankins JS (2021). Sickle cell disease and ventricular myocardial strain: A systematic review. Pediatr Blood Cancer, 68(6), e28973.
- Parsons MW, Whipple NS, Poppe MM, Mendez JS, Cannon DM, Burt LM (2020). The use and efficacy of chemotherapy and radiotherapy in children and adults with pilocytic astrocytoma. J Neurooncol, 151(2), 93-101.
- Mueller S, Taitt JM, Villanueva-Meyer JE, Bonner ER, Nejo T, Lulla RR, Goldman S, Banerjee A, Chi SN, Whipple NS, Crawford JR, Gauvain K, Nazemi KJ, Watchmaker PB, Almeida ND, Okada K, Salazar AM, Gilbert RD, Nazarian J, Molinaro AM, Butterfield LH, Prados MD, Okada H (2020). Mass cytometry detects H3.3K27M-specific vaccine responses in diffuse midline glioma. J Clin Invest, 130(12), 6325-6337.
- Mondal G, Lee JC, Ravindranathan A, Villanueva-Meyer JE, Tran QT, Allen SJ, Barreto J, Gupta R, Doo P, Van Ziffle J, Onodera C, Devine P, Grenert JP, Samuel D, Li R, Metrock LK, Jin LW, Antony R, Alashari M, Cheshier S, Whipple NS, Bruggers C, Raffel C, Gupta N, Kline CN, Reddy A, Banerjee A, Hall MD, Mehta MP, Khatib Z, Maher OM, Brathwaite C, Pekmezci M, Phillips JJ, Bollen AW, Tihan T, Lucas JT Jr, Broniscer A, Berger MS, Perry A, Orr BA, Solomon DA (2020). Pediatric bithalamic gliomas have a distinct epigenetic signature and frequent EGFR exon 20 insertions resulting in potential sensitivity to targeted kinase inhibition. Acta Neuropathol, 139(6), 1071-1088.
- Lucas CG, Villanueva-Meyer JE, Whipple N, Oberheim Bush NA, Cooney T, Chang S, McDermott M, Berger M, Cham E, Sun PP, Putnam A, Zhou H, Bollo R, Cheshier S, Poppe MM, Fung KM, Sung S, Glenn C, Fan X, Bannykh S, Hu J, Danielpour M, Li R, Alva E, Johnston J, Van Ziffle J, Onodera C, Devine P, Grenert JP, Lee JC, Pekmezci M, Tihan T, Bollen AW, Perry A, Solomon DA (2019). Myxoid glioneuronal tumor, PDGFRA p.K385-mutant: clinical, radiologic, and histopathologic features. Brain Pathol, 30(3), 479-494.
- Whipple NS, Naik RJ, Kang G, Moen J, Govindaswamy SD, Fowler JA, Dowdy J, Penkert R, Joshi VM, Hankins JS (2018). Ventricular global longitudinal strain is altered in children with sickle cell disease. Br J Haematol, 183(5), 796-806.
- McClain KL, Picarsic J, Chakraborty R, Zinn D, Lin H, Abhyankar H, Scull B, Shih A, Lim KPH, Eckstein O, Lubega J, Peters TL, Olea W, Burke T, Ahmed N, Hicks MJ, Tran B, Jones J, Dauser R, Jeng M, Baiocchi R, Schiff D, Goldman S, Heym KM, Wilson H, Carcamo B, Kumar A, Rodriguez-Galindo C, Whipple NS, Campbell P, Murdoch G, Kofler J, Heales S, Malone M, Woltjer R, Quinn JF, Orchard P, Kruer MC, Jaffe R, Manz MG, Lira SA, Parsons DW, Merad M, Man TK, Allen CE (2018). CNS Langerhans cell histiocytosis: Common hematopoietic origin for LCH-associated neurodegeneration and mass lesions. Cancer, 124(12), 2607-2620.
- Whipple NS, Marion LL, Dansie DM, Murina AT, Megason GC, Vijayakumar V, Herrington BL (2018). [18F]FDG-PET for evaluating pediatric Rosai-Dorfman disease. Pediatr Hematol Oncol, 35(3), 177-180.
- Whipple NS, Schwartz JR, Nottage KA (2017). DAT-positive Plasmodium ovale malaria presenting in a child with sickle cell anemia. Am J Hematol, 92(7), 722.
- Whipple NS, Bennett EE, Kaza E, OConnor M (2016). Umbilical Cord Pseudocyst in a Newborn. J Pediatr, 177, 333.
- Ku E, Thomas M, Ho CH, Whipple NS, Abdul-Rahman O, Megason GC, Herrington BL, Carmody JB, Charlton JR (2014). Index of suspicion. Case 1: fever, diarrhea, jaundice, and confusion in an 18-year-old male. Case 2: severe anemia in a 6-month-old girl. Case 3: red urine in a 4-month-old boy. Pediatr Rev, 35(3), 129-35.
- Whipple N (2011). Remembering Peru: what those who made the journey had to say. J Miss State Med Assoc, 52(9), 289-92.
- Abdullah R, Shukla M, Whipple N, Gordon C, Majumdar S, Duchan E, Feinberg A (2010). Index of suspicion. Pediatr Rev, 31(5), 211-5.
Book Chapter
- Whipple NS, Gajjar A (2019). Chapter 33: Targeted Therapies for Pediatric Central Nervous System Tumors. In: Predictive Biomarkers in Oncology: Applications in Precision Medicine. Sunil Badve and George Kumar, editors. Springer International Publishing (2019). 375-382. doi:10.1007/978-3-319-95228-4.
Case Report
- Whipple NS, Moreau DA, Moulds JM, Hankins JS, Wang WC, Nottage KA (2015). Paroxysmal cold hemoglobinuria due to an IgA Donath-Landsteiner antibody. Pediatr Blood Cancer, 62(11), 2044-6.
- Whipple NS, Whipple PD, Nelson CR, Bollo RJ (2011). Puzzler: Three-year-old with upper extremity hemiparesis. Contemp Pediatr, 28(9), 75-84.
- Baker C, Crevelt J, Whipple NS, Bollo R, Cheshier S (Accepted for publication on 09/02/2021). Treatment of a symptomatic thalamic pilocytic astrocytoma with reservoir placement and laser interstitial thermal therapy. J Neurosurg Pediatr.
Newspaper
- Whipple N (March 6, 2005). NICHOLAS WHIPPLE: Community college route was the right choice. Northeast Mississippi Daily Journal.
Video/Film/CD/Web/Podcast
- Whipple NS, Wirkus P (2021). Pediatric Central Nervous System Tumors. The Virtual Curbside Podcast. Utah Chapter of the American Academy of Pediatrics [Podcast]. https://www.aaputah.org/: American Academy of Pediatrics, Utah Chapter.
- Whipple NS, Wirkus P (2021). Cancer Therapies in a Nutshell. The Virtual Curbside Podcast. Utah Chapter of the American Academy of Pediatrics. [Podcast]. https://www.aaputah.org/.
- Whipple NS (2021). A Career in Pediatric Hematology-Oncology. Video recorded for University of Utah medical students to view for career planning and decision making. [Video]. University of Utah School of Medicine.