Adam M. Spivak,
MD
Languages Spoken: English
Dr. Spivak joined the Division of Infectious Diseases in October 2011 after completing Infectious Diseases fellowship training at Johns Hopkins University School of Medicine. His primary focus is on translational research exploring HIV persistence and strategies for viral eradication. At the University of Utah, Dr. Spivak spends the majority of his time in a basic science laboratory working with his scientific mentor Dr. Vicente Planelles in the Department of Pathology. Working with members of the Planelles lab, he conducts ongoing research into the nature of HIV persistence. He cares for HIV patients as a member of the Clinic 1A staff at the University of Utah Hospital and attends on the inpatient Infectious Diseases consult service at both the University and VA Hospitals.
During fellowship, Dr. Spivak spent three years in the laboratory of Dr. Robert Siliciano where he studied cellular reservoirs of HIV and helped to run a pilot clinical trial of a novel HIV eradication strategy. In May 2011, Dr. Spivak was awarded a Bill and Melinda Gates Foundation Grand Challenges Explorations Grant for a research proposal describing an in vitro screening assay to identify compounds able to selectively induce apoptosis in HIV infected cells. In 2016 Dr. Spivak was selected by the Doris Duke Charitable Foundation to receive a Clinical Scientist Development Award that supports his current research developing novel strategies to eliminate the HIV latent reservoir.
Dr. Spivak joined the Division of Infectious Diseases at the University of Utah in the fall of 2011 after completing residency and fellowship training at Johns Hopkins University School of Medicine. He cares for HIV patients as a member of the Clinic 1A staff at the University of Utah Hospital and attends on the inpatient Infectious Diseases consult service at both the University and VA Hospitals.
Clinical Locations
Infectious Diseases, Clinic 1A
801-585-2031
Specialties
Board Certification and Academic Information
| Academic Departments | Internal Medicine
-
Assistant Professor Pathology - Adjunct Assistant Professor |
| Academic Divisions | Infectious Diseases Microbiology and Immunology |
| Board Certification | American Board of Internal Medicine (Sub: Infectious Disease) American Board of Internal Medicine (Internal Medicine) |
Patient Rating
The Patient Rating score is an average of all responses to care provider related questions on our nationally-recognized Press Ganey Patient Satisfaction Survey.
Responses are measured on a scale of 1 to 5 with 5 being the best score.
Likelihood of recommending care provider
5.0/ 5
Care provider spoke using clear language
5.0/ 5
Care provider's explanation of condition/problem
5.0/ 5
My confidence in care provider
5.0/ 5
Care provider's effort to include me in decisions
5.0/ 5
Wait time at clinic
4.8/ 5
Time care provider spent with me
5.0/ 5
Care provider's concern for questions & worries
5.0/ 5
Care provider's friendliness and courtesy
5.0/ 5
Patient Comments
Patient comments are gathered from our Press Ganey Patient Satisfaction Survery and displayed in their entirety. Patients are de-identified for confidentiality and patient privacy.
UofU Patient
March 19, 2019
dr Adam Spivak is really great guy. love him!!!!!
UofU Patient
January 29, 2019
dr Adam Spivak is an exceptional doctor- he is very thorough he is such a nice guy & has such kindness and compassion and I would have no other doctor treat me if I have my choice -he's an amazing guy and I considered a dear friend almost instantly meeting him the first few times
UofU Patient
January 26, 2019
Dr Adam Spivak is awesome!
UofU Patient
October 02, 2018
Dr Adam Spivak is the epitome of a doctor health care provider and overall an amazing guy to have take care of you He truly excels at this and Never ceases to amaze me with his compassion, knowledge, kindness & just in my overall health care
UofU Patient
July 11, 2018
Dr Spivak is like no other physician i have ever had. in addition to his outstanding clinical knowledge and skills, he always has spent as much time as needed discussing my care and NEVER has left me feeling as though he needed to keep moving or finish up the appointment. He always seems genuinely interested and concerned about what's going on in all aspects of my life
UofU Patient
June 19, 2018
I am blown away at how supportive, friendly, insightful and knowledgeable Dr Spivak's entire team is. truly some of the best I've ever met
UofU Patient
June 11, 2018
I answer very good all these questions Dr Adam Spivak has an incredible doctor , he provides top notch level care very compassionate and willing to help anyway he can and does ,Is see him every day if I could, just knowing I'm always looked after
UofU Patient
April 24, 2018
Dr. Spivac is a very bright and patient individual that makes him who he is. I'm very happy to have him as my Doctor. Thank you.
UofU Patient
March 05, 2018
Dr Adam Spivak is an incredible doctor I love this man to death he's taking me up most phenomenal incredible care of me in the past three years that I've seen him I recommend him highly to anybody he has such compassion he's so cool and just an amazing guy
UofU Patient
February 25, 2018
Dr Adam Spivak is an incredible doctor I am he gets things done as far as treatment he never really has had to do anything as far as my specific case he has sent me to other doctors, but is very compassionate is very thorough and he's really nice guy to Del Webb but is very compassionate is very thorough and really nice guy to deal with , and I love that he's my doctor and under his care
UofU Patient
January 22, 2018
Dr Adam Spivak is one of the most incredible human beings I've ever met in my entire life this man is undeniably compassionate infinitely thorough and I will never go to another doctor as long as I can I want to see him in a my future healthcare he is just an incredible person, &doctor
UofU Patient
January 14, 2018
I was amazed at the level of care I received and the time taken for answering personal concerns. It was an outstanding experience
UofU Patient
September 26, 2017
Dr Adam Spivak is outstanding in every way, best doctor ever.
UofU Patient
September 18, 2017
BEST Doc I've ever had in my life
UofU Patient
August 05, 2017
I absolutely adore and love Dr Adam Spivak . he has been so kind and conpassionate and just cares for me as a doctor in a way I need and I think only could genuinely get from him . I'm sure there are others .. but he's just been exactly what I need Thru my health diagnosis from two years now and just everything else in between , he's an incredible guy and a very thorough doctor . I couldn't genuinely asked for anyone better
UofU Patient
July 21, 2017
dr Adam Spivak is an incredible infinitely competent amazing doctor I couldn't ask for better care he is and has been so compassionate and soul progressive and just an amazing guy to deal with in my healthcare I can ask for a better doctor and if I have & see my way fit ...He will ALWAYS be my doctor -I COULD NOT ASK FOR BETTER THAN ADAM SPIVAK
UofU Patient
July 03, 2017
dr Adam Spivak is the best doctor ever!!!!!
UofU Patient
May 21, 2017
dr Adam Spivak is an incredible doctor he's very kind he's very compassionate is very proactive he wants to totally take care of him and care for you and treat you in the way that you should AdamSpivak is an amazing doctor and anybody could learn amazing care or "bedside manner" and just overall kindness..he's incredible
UofU Patient
April 11, 2017
Dr Spivak is outstanding
UofU Patient
March 13, 2017
Very good
UofU Patient
February 28, 2017
Dr Spivack he is an amazing human been as well his assistant makes patient feel very welcome.
UofU Patient
February 13, 2017
Dr Adam Spivak is an incredible doctor and man and fellow human being . I am so glad he is my doctor . I will never be under anyone else's care if I have my way ... He's an incredible amazing caring guy and I am so glad he has taken care of me each and every time ...ever since I started in under his care
UofU Patient
December 05, 2016
Dr Adam Spivak is one of the kindest most caring amazing infinitely compassionate doctors I've ever had . I will not go to anyone else . I would travel to wherever he is , He's that amazing !!
UofU Patient
October 17, 2016
I know he ( Dr Spivak ) was busy and I'd seen him the month b4 , so I get it. Dr Spivak is the infinite best , I just really appreciate him and absolutely love his care and treatment and everything he's done for me Thank You, Dr Spivak
UofU Patient
September 19, 2016
I honestly love Dr Spivak ,as he truly has got things done for me , he's really done so much for me , I could t ask for a better Doctor , and I'll continue to see him thru my lifetime as I see fit ,.. He's Amazing
UofU Patient
September 12, 2016
Dr. Spivak was great at explaining everything and making sure I understood everything. Resident Russell Johnson did a great work up and history to better understand what was going good on and make a plan with the doctor for me.
UofU Patient
July 31, 2016
Best care provider i have ever met.
UofU Patient
July 11, 2016
Dr Adam Spivak Is the best , he will be my doctor from here on out
UofU Patient
April 26, 2016
Provider was the best Doctor I have ever dealt with.
UofU Patient
February 27, 2016
We feel very confident in our provider. He asks good questions of us, and when he doesn't have an answer he seeks consultation. Amazing bedside manner. Too many good qualities to list them all. Suffice it to say he is the best,
UofU Patient
February 05, 2016
Dr Adam Spivak is just an incredible and amazing Doctor , I will only ever see him , he's that incredible
UofU Patient
November 10, 2015
Dr Adam Spivak you are a god send , You truly have kept me going to get better, inspired me to feel at ease and to be able to get well, your confidence, your kind and generous and just infinitely compassionate demeanor as a whole, I couldnt ask for a better doctor honestly, You are the best, as well as your other assisting staff, you have all been so kind. Thank you, You have no idea what a difference its made for me to try to get healthy and back to some kind of life after my very grim episode I faced and almost lost the battle with a some months ago, To be that close to death and yet end up where I am , I thank you solely as well as the ICU staff at LDS Hospital . who all saved my life truly. Thank you
UofU Patient
September 17, 2015
This team of people that I have encountered and that have cared for me have been so truly AMAZING AND JUST FANTASTIC AND TRULY WHAT I HAVE NEEDED AS A PATIENT
UofU Patient
August 07, 2015
Dr Spivak is an excellent doctor and I can't thank him enough for the care he has shown and given me.
UofU Patient
July 17, 2015
dr Spivac is supercalafrajalisticexpialidocious don't think there is a better word to describe him. well if he has an off day maybe he is just super terrific
UofU Patient
March 29, 2015
I have never been treated so well by anyone in my life. The Doctors and Staff at Clinic 1 A are both professional and Caring. I don't know what I would do without their support
UofU Patient
November 18, 2014
dr's have a difficult job barring and showing concern for so many people dr. Spivac always makes me feel that I am an individual not just a number
UofU Patient
October 02, 2014
I was VERY impressed with the time that Dr. S took with me to discuss my medical concerns! He was very patient and answered all of my questions!
UofU Patient
March 13, 2014
I have incredible confidence of the people I see at Clinic 1A.
UofU Patient
February 04, 2014
I have nothing but the highest respect for my Dr's and staff at the Clinic. They walk on water is how much I respect them. I couldn't go through this without them. That is how awesome they are. I have been alone and on my own most of my life. I have been treated so well.
UofU Patient
January 14, 2014
my doctor, Adam Spivak, is exceptional and I feel so grateful that he is my attending doctor.
UofU Patient
August 13, 2013
Dr. Spivak is the epitome of how a doctor should behave; in so much as the excitement, outlook and assurity that the journey is not one that will be taken alone. I have never had a team so committed and support me; they are the energy behind a healthy and emotional state of recovery.
UofU Patient
May 07, 2013
The care, in all respects, has been exceptional and first-rate.
UofU Patient
April 09, 2013
I travel from Logan to Salt Lake City for my appointments because I don't want to see any other doctor. Dr. Spivak makes me feel very comfortable and confident in the treatment I am receiving. He makes me feel that my opinion always count on the final decision for treatment. He is a doctor who really cares.
Dr. Spivak joined the Division of Infectious Diseases in October 2011 after completing Infectious Diseases fellowship training at Johns Hopkins University School of Medicine. His primary focus is on translational research exploring HIV persistence and strategies for viral eradication. At the University of Utah, Dr. Spivak spends the majority of his time in a basic science laboratory working with his scientific mentor Dr. Vicente Planelles in the Department of Pathology. Working with members of the Planelles lab, he conducts ongoing research into the nature of HIV persistence. He cares for HIV patients as a member of the Clinic 1A staff at the University of Utah Hospital and attends on the inpatient Infectious Diseases consult service at both the University and VA Hospitals.
During fellowship, Dr. Spivak spent three years in the laboratory of Dr. Robert Siliciano where he studied cellular reservoirs of HIV and helped to run a pilot clinical trial of a novel HIV eradication strategy. In May 2011, Dr. Spivak was awarded a Bill and Melinda Gates Foundation Grand Challenges Explorations Grant for a research proposal describing an in vitro screening assay to identify compounds able to selectively induce apoptosis in HIV infected cells. In 2016 Dr. Spivak was selected by the Doris Duke Charitable Foundation to receive a Clinical Scientist Development Award that supports his current research developing novel strategies to eliminate the HIV latent reservoir.
Dr. Spivak joined the Division of Infectious Diseases at the University of Utah in the fall of 2011 after completing residency and fellowship training at Johns Hopkins University School of Medicine. He cares for HIV patients as a member of the Clinic 1A staff at the University of Utah Hospital and attends on the inpatient Infectious Diseases consult service at both the University and VA Hospitals.
Academic Locations
School of Medicine
801-587-1964
Board Certification and Academic Information
| Academic Departments | Internal Medicine
-
Assistant Professor Pathology - Adjunct Assistant Professor |
| Academic Divisions | Infectious Diseases Microbiology and Immunology |
| Board Certification | American Board of Internal Medicine (Sub: Infectious Disease) American Board of Internal Medicine (Internal Medicine) |
Education History
| Fellowship | Johns Hopkins University School of Medicine Infectious Diseases Fellow |
| Chief Resident | Johns Hopkins University School of Medicine Internal Medicine Chief Resident |
| Residency | Johns Hopkins University School of Medicine Internal Medicine Resident |
| Internship | Johns Hopkins University School of Medicine Internal Medicine Intern |
| Professional Medical | University of Maryland School of Medicine Medicine M.D. |
| Undergraduate | Princeton University English Literature A.B. |
Selected Publications - Journal Articles
Journal Article
- Spivak AM, Nell RA, Petersen M, Martins L, Sebahar P, Looper RE, Planelles V (2018 Nov). Synthetic Ingenols Maximize Protein Kinase C-Induced HIV-1 Latency Reversal. Antimicrob Agents Chemother, 62(11).
- Szaniawski MA, Spivak AM, Bosque A, Planelles V (2018 Oct 8). Sex influences SAMHD1 activity and susceptibility to HIV-1 in primary human macrophages. (Epub ahead of print) J Infect Dis.
- Macedo AB, Novis CL, De Assis CM, Sorensen ES, Moszczynski P, Huang SH, Ren Y, Spivak AM, Jones RB, Planelles V, Bosque A (2018 Oct 4). Dual TLR2 and TLR7 agonists as HIV latency-reversing agents. JCI Insight, 3(19).
- Macedo AB, Resop RS, Martins LJ, Szaniawski MA, Sorensen ES, Spivak AM, Nixon DF, Jones RB, Planelles V, Bosque A (2018 Sep). Influence of Biological Sex, Age, and HIV Status in an In Vitro Primary Cell Model of HIV Latency Using a CXCR4 Tropic Virus. AIDS Res Hum Retroviruses, 34(9), 769-777.
- Szaniawski MA, Spivak AM, Cox JE, Catrow JL, Hanley T, Williams ESCP, Tremblay MJ, Bosque A, Planelles V (2018 May 15). SAMHD1 Phosphorylation Coordinates the Anti-HIV-1 Response by Diverse Interferons and Tyrosine Kinase Inhibition. mBio, 9(3).
- Abdel-Mohsen M, Kuri-Cervantes L, Grau-Exposito J, Spivak AM, Nell RA, Tomescu C, Vadrevu SK, Giron LB, Serra-Peinado C, Genesca M, Castellvi J, Wu G, Del Rio Estrada PM, Gonzalez-Navarro M, Lynn K, King CT, Vemula S, Cox K, Wan Y, Li Q, Mounzer K, Kostman J, Frank I, Paiardini M, Hazuda D, Reyes-Teran G, Richman D, Howell B, Tebas P, Martinez-Picado J, Planelles V, Buzon MJ, Betts MR, Montaner LJ (2018 Apr 18). CD32 is expressed on cells with transcriptionally active HIV but does not enrich for HIV DNA in resting T cells. Sci Transl Med, 10(437).
- Bosque A, Nilson KA, Macedo AB, Spivak AM, Archin NM, Van Wagoner RM, Martins LJ, Novis CL, Szaniawski MA, Ireland CM, Margolis DM, Price DH, Planelles V (2017 Jan 31). Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation. Cell Rep, 18(5), 1324-1334.
- Spivak AM, Larragoite ET, Coletti ML, Macedo AB, Martins LJ, Bosque A, Planelles V (2016 Dec 20). Janus kinase inhibition suppresses PKC-induced cytokine release without affecting HIV-1 latency reversal ex vivo. Retrovirology, 13(1), 88.
- Martins LJ, Bonczkowski P, Spivak AM, De Spiegelaere W, Novis CL, DePaula-Silva AB, Malatinkova E, Trypsteen W, Bosque A, Vanderkerckhove L, Planelles V (2016 Feb). Modeling HIV-1 Latency in Primary T Cells Using a Replication-Competent Virus. AIDS Res Hum Retroviruses, 32(2), 187-93.
- Garrido C, Spivak AM, Soriano-Sarabia N, Checkley MA, Barker E, Karn J, Planelles V, Margolis DM (2016). HIV Latency-Reversing Agents Have Diverse Effects on Natural Killer Cell Function. Front Immunol, 7, 356.
- Spivak AM, Bosque A, Balch AH, Smyth D, Martins L, Planelles V (2015 Oct). Ex Vivo Bioactivity and HIV-1 Latency Reversal by Ingenol Dibenzoate and Panobinostat in Resting CD4(+) T Cells from Aviremic Patients. Antimicrob Agents Chemother, 59(10), 5984-91.
- Pache L, Dutra MS, Spivak AM, Marlett JM, Murry JP, Hwang Y, Maestre AM, Manganaro L, Vamos M, Teriete P, Martins LJ, Konig R, Simon V, Bosque A, Fernandez-Sesma A, Cosford ND, Bushman FD, Young JA, Planelles V, Chanda SK (2015 Sep 9). BIRC2/cIAP1 Is a Negative Regulator of HIV-1 Transcription and Can Be Targeted by Smac Mimetics to Promote Reversal of Viral Latency. Cell Host Microbe, 18(3), 345-53.
- Spivak AM, Andrade A, Eisele E, Hoh R, Bacchetti P, Bumpus NN, Emad F, Buckheit R 3rd, McCance-Katz EF, Lai J, Kennedy M, Chander G, Siliciano RF, Siliciano JD, Deeks SG (2014 Mar). A pilot study assessing the safety and latency-reversing activity of disulfiram in HIV-1-infected adults on antiretroviral therapy. Clin Infect Dis, 58(6), 883-90.
- Weil AF, Ghosh D, Zhou Y, Seiple L, McMahon MA, Spivak AM, Siliciano RF, Stivers JT (2013 Feb 5). Uracil DNA glycosylase initiates degradation of HIV-1 cDNA containing misincorporated dUTP and prevents viral integration. Proc Natl Acad Sci U S A, 110(6), E448-57.
- Spivak AM, Salgado M, Rabi SA, OConnell KA, Blankson JN (2011 Oct). Circulating monocytes are not a major reservoir of HIV-1 in elite suppressors. J Virol, 85(19), 10399-403.
- Gaillard S, Dinoso JB, Marsh JA, DeZern AE, OConnell KA, Spivak AM, Alwood K, Durand CM, Ambinder RF, Blankson JN (2011 Jul). Sustained elite suppression of replication competent HIV-1 in a patient treated with rituximab based chemotherapy. J Clin Virol, 51(3), 195-8.
- Spivak AM, Rabi SA, McMahon MA, Shan L, Sedaghat AR, Wilke CO, Siliciano RF (2011 Jul). Short communication: dynamic constraints on the second phase compartment of HIV-infected cells. AIDS Res Hum Retroviruses, 27(7), 759-61.
- Spivak AM, Brennan TP, OConnell KA, Sydnor E, Williams TM, Siliciano RF, Gallant JE, Blankson JN (2010 Feb 1). A case of seronegative HIV-1 infection. J Infect Dis, 201(3), 341-5.
- Dinoso JB, Kim SY, Wiegand AM, Palmer SE, Gange SJ, Cranmer L, OShea A, Callender M, Spivak A, Brennan T, Kearney MF, Proschan MA, Mican JM, Rehm CA, Coffin JM, Mellors JW, Siliciano RF, Maldarelli F (2009 Jun 9). Treatment intensification does not reduce residual HIV-1 viremia in patients on highly active antiretroviral therapy. Proc Natl Acad Sci U S A, 106(23), 9403-8.
Review
- Spivak AM, Planelles V (2018 Jan 29). Novel Latency Reversal Agents for HIV-1 Cure. [Review]. Annu Rev Med, 69, 421-436.
- Spivak AM, Planelles V (2016 Jan). HIV-1 Eradication: Early Trials (and Tribulations). [Review]. Trends Mol Med, 22(1), 10-27.
- Barber AE, Norton JP, Spivak AM, Mulvey MA (2013 Sep). Urinary tract infections: current and emerging management strategies. [Review]. Clin Infect Dis, 57(5), 719-24.
- Pradilla G, Nagahama Y, Spivak AM, Bydon A, Rigamonti D (2010 Nov). Spinal epidural abscess: current diagnosis and management. [Review]. Curr Infect Dis Rep, 12(6), 484-91.
- Spivak AM, Sydnor ER, Blankson JN, Gallant JE (2010 Jun 19). Seronegative HIV-1 infection: a review of the literature. [Review]. AIDS, 24(10), 1407-14.
Book
- Spivak AM (). Harrison’s Principles of Internal Medicine Self-Assessment & Board Review. [contributing editor] (17th). New York, NY: McGraw Hill.
Book Chapter
- Spivak A, Sosnay P, Cosgrove S (). Soft Tissue and Bone Infection. In The Osler Medical Handbook (2nd, Chapter 65). Philadelphia, PA: Elsevier Mosby.
- Spivak A, Zaas A, Cheng A, Auwaerter P (). CNS Infections. In The Osler Medical Handbook (2nd, Chapter 57). Philadelphia, PA: Elsevier Mosby.
Case Report
- Rachakonda T, Kendall B, Spivak AM, Boltax J (2017 Summer). Pleural Effusion Caused by Bacillus Calmette-Guerin Immunotherapy for Bladder Cancer. Open Forum Infect Dis, 4(3), ofx126.
- Vargas JD, Spivak AM (2009 Jun). A perfect storm. Gastric bezoar. Am J Med, 122(6), 519-21.
- Rodriguez ED, Bluebond-Langner R, Spivak AM, Eisig SB (2007 Sep). Surgical management of maxillofacial uremic osteodystrophy: a case report. J Oral Maxillofac Surg, 65(9), 1825-9.