Board Certification
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Royal College of Surgeons of Canada
Royal College of Physicians and Surgeons of Canada
American Board of Internal Medicine (Sub: Hematology)
American Board of Internal Medicine (Internal Medicine)
Educational Commission for Foreign Medical Graduates
Licentiate of the Medical Council of Canada
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Patient Rating
The patient rating score is an average of all responses on our patient experience survey. The rating averages scores for all questions about care from our providers.
The scale on which responses are measured is 1 to 5 with 5 being the best score.
Patient Comments
Patient comments are gathered from our patient experience survey and displayed in their entirety. For the convenience of our visitors, some patient comments have been translated from their original language into English while preserving their original meaning as accurately as possible. Patients are de-identified for confidentiality and patient privacy.
Tough to get an appointment, but worth the wait.
Very courteous Dr, who explained everything about my blood test certainly assured me that I was doing well and he would like to see me in a year his staff we're all very courteous
Clear, concise. Follow up
He is very professional [TRANSLATED]
He is a great doctor
Excellent care by Gretchen the MA. Dr Parker was only in the visit for a couple minutes and aloof. I was pleased with the care taken thanks to MA not necessarily the doctor.
I found Dr. Parker to be competent and thorough.
Excellent facility also.
Dr. Parker monitors my chronic condition and takes an interest in how I'm doing. I appreciate his watchfulness.
We feel that he just wasn't straightforward with us. And didn't do anything to prepare for the visit
so so
Dr. Parker is kind and attentive. I've been a patient of his practice for almost 3 years. I'm grateful for their concern for me and my health.
Dr. Parker is a down to earth physician. He explains things in easily understood terms. He listens to my concerns and answers clearly. He is calm and makes me at ease.
My care providers did their best to allay any concerns, I may have. The unanswered segments do not apply at this time. I feel assured they will be diligent in trying to obtain a diagnoses.
As mine is an on-going condition, we simply monitored my current status - noting little change or reason for alarm. All my questions were addressed to my complete satisfaction.
Dr. Parker is incredibly knowledge and helpful. His personal review and interpretation of my blood smear helped him to provide an informed decision about my condition. He is personable and calm and conveys a sense of certainty.
Dr. Parker is a highly knowledgeable practitioner who is low key and informative. His explanations and instructions are straightforward and understandable.
Good experience [TRANSLATED]
Dr Parker is an excellent doctor. Very knowledgeable and caring.
Dr. Parker always takes good care of me. He is a doctor you can trust with a lot of knowledge.
trying meds to improve my energy level
Always very good and I and my family are always happy with thier care for me
Dr. said all of 25 words when he finally came into the room. No exaggeration. I mostly dealt with the PA/Nursing assistant. The appointment felt rushed, and secretive almost like there was a bias because I had called in a few times to get my appointment moved up sooner. When I tried to ask a question about the lab markers, I was met with the phrase "don't even go down that route" as if my questions were annoying or not warranted. I've had pretty good experiences at Univ of Utah. This wasn't one of them unfortunately. I mean I'm happy I don't have anything wrong with me I supposed from a hematology standpoint, but they could have at least shown me what the manual smear interpretation said. I feel like that is my right to know as a patient.
Dr Parker has been a blessing in helping us.
Dr. Parker was most attentive and knowledgeable about my condition. He gave me a generous amount of his time to explain his plan of care for me.
Very understanding and clear with information.
I do not how to answer this question, just had a very brief meeting. He explain about the other blood test.
I thought I he PA Kara was awesome! Super friendly and personable. Dr. Parker was very kind as well. Very quiet. I trust his knowledge. I would have e felt more comfortable had he sat down. I felt awkward looking up at him. Otherwise, my visit was quick and he was very nice.
Never saw this Dr its very upsetting to wait a long time for an appointment and then only see a P A when waiting to finally see a Dr and then not made me feel like my issue wasnt important enough for anyone to care it simply was just push the patient off from bugging the primary care cause what was treated I feel was something my primary care dr could have taken care of right away cause we had discussed doing these things at a prior visit
Hw was very professional and explained everything to me too the time to listen to me.
Good experience
He was. Amazing and the nicest bed side manner
I would not recommend Dr. Parker to anyone.
The doctor ordered a few more blood tests and a urine test. The doctor said his services were no longer needed when they came back normal.
Good professional [TRANSLATED]
Dr Charles Parker is amazing !! He is not only very knowledgable but also very kind and personal. Very lucky to have him as my doctor.
Caring & knowledgeable.
I feel that the care I received from Gretchen and Dr Parker was excellent. It has helped me relax about the laboratory abnormality and, also, motivate me to take even better care of my health.
Excellent!
Dr. Parker is such a valuable asset. He cares and is so knowledgeable.
Dr. Parker is very friendly and explained the issues to me in clear, layperson's language.
Dr. Parker was very thorough in his review of my test results. I appreciate him wanting to wait and review my MRI with the radiologist when Dr. Parker noted contradictory or inconsistent interpretations. I also appreciate his description of what he was doing, keeping me informed.
Outstanding
I find Dr. Parker VERY good to work with. His demeanor is very soothing, open and helpful.
It is easy to tell that Dr. Parker cares about me and all his patients.
He was direct, knowledgeable and knew his information. Very kind.
He is friendly, caring and very aware of all my concerns.
Absolutely love Dr. Parker and his PA! His concern for me and my health was absolutely amazing! The staff as a whole in his clinic are extremely friendly and helpful!
I have been seeing Dr Parker for at least 3 years and have received good care from him.
He is excellent, very knowledgeable, patient, & willing to take the necessary time to explain any question you may have.
The nurse practitioner listened to all of my questions and then left the screen to get responses from the doctor. She said she would return with his responses. After quite some time my doctor appeared on the screen. He. said that his nurse practitioner would take care of all the questions I had asked. I asked the doctor one other question that I thought of. We discussed this matter and he discussed medicine that I would take. I never heard from the n.p. She thought the doctor answered all questions. I sent an inquiry about responses to my questions. The n.p. told me of the confusion but I would still like to get answers to the questions I had.
Dr Parker is great
need injection shots, nothing on the risks talked about
I would not recommend this dr.
His experience as a hematologist was very apparent. Where other doctors had said, ¿We just don't know what's wrong,¿ Dr. Parker ordered tests to see exactly what's going on with me personally. A kind, gentle doctor.
Respectful, knowledgeable, courteous, accessible to discuss my situation
we like Dr. Parker
Very Thourghow
Didn't answer any of my questions. Told me nothing was wrong and sent me out.
Dr. Parker is very experienced and knowledgeable about my health problem.
His explanation of my condition and the stability of my lab results were easy to understand and how he emphasized the important results and how they affected my overall health
Dr. Parker is very experienced and knowledgeable about my health problem.
He is incredibly knowledgeable on the subject of PNH
Had a great discussion and I fully understood everything she explained to me.
He is such a kind doctor and very thorough with all my health needs
Very informative and knowledgeable
Dr Parker was easy to understand. He explained his thoughts in a manner I could understand.
Dr Parker's NP/PA was very kind and explained a lot to me about what was going on. However, when Dr Parker himself came in, he was barely in there for even 2 minutes and didn't explain anything to me! Just said that the blood work I came in for wasn't concerning, it may just be "my normal." Then he ordered extra blood tests, but he didn't give any other explanation as to why or the risks of my levels being abnormal. He just said that they would contact me the next day, which didn't happen. Anyway, thank you to Dr Parker's NP/PA for helping me out and for being so kind!
Board Certification and Academic Information
| Academic Departments |
Internal Medicine
-Professor |
|---|---|
| Academic Divisions |
Hematology & Hematologic Malignancies
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| Board Certification |
Royal College of Surgeons of Canada
Royal College of Physicians and Surgeons of Canada
American Board of Internal Medicine (Sub: Hematology)
American Board of Internal Medicine (Internal Medicine)
Educational Commission for Foreign Medical Graduates
Licentiate of the Medical Council of Canada
|
Education history
| Undergraduate | English - University of North Carolina | A.B. |
|---|---|---|
| Professional Medical | Medicine - University of North Carolina | M.D. |
| Internship | North Carolina Memorial Hospital | Intern |
| Residency | Internal Medicine - North Carolina Memorial Hospital | Resident |
| Fellowship | Hematology/Oncology - Duke University Medical Center | Fellow |
Selected Publications
Journal Article
- Bohnsack JF, Zhou XN, Williams PA, Cleary PP, Parker CJ, Hill H (1991). Purification of the proteinase from group B streptococci that inactivates human C5a. Biochimica et biophysica acta, 1079(2), 222-8.
- Abou-Ismail MY, Prchal JT, Deininger MW, Parker CJ, Lim M (2021). Anticoagulation management post-transjugular intrahepatic portosystemic shunt in portal hypertension associated with myeloproliferative neoplasms. Blood coagulation & fibrinolysis, 32(8), 578-583.
- Swierczek SI, Piterkova L, Jelinek J, Agarwal N, Hammoud S, Wilson A, Hickman K, Parker CJ, Cairns BR, Prchal J (2012). Methylation of AR locus does not always reflect X chromosome inactivation state. Blood, 119(13), e100-9.
- Whatley RE, Lewis MS, Zimmerman GA, McIntyre TM, Parker CJ, Stevens DL, Prescott S (1988). The regulation of synthesis of platelet-activating factor by endothelial cells. Chest, 93(3 Suppl), 110S-111S.
- Cheung AK, Parker CJ, Wilcox (1989). Effects of two types of cobra venom factor on porcine complement activation and pulmonary artery pressure. Clinical and experimental immunology, 78(2), 299-306.
- Janatova J, Cheung AK, Parker C (1991). Biomedical polymers differ in their capacity to activate complement. Complement and inflammation, 8(2), 61-9.
- Parker CJ, Bernshaw NJ, Wilcox L (1990). Analysis of the binding of human C3b to glycoproteins on rabbit and sheep erythrocytes. Complement and inflammation, 7(1), 1-17.
- Ahmed KB, Warner SL, Chen A, Gourley ES, Liu X, Vankayalapati H, Nussenzveig R, Prchal JT, Bearss DJ, Parker C (2011). In vitro and in vivo characterization of SGI-1252, a small molecule inhibitor of JAK2. Experimental hematology, 39(1), 14-25.
- Singal AK, Parker C, Bowden C, Thapar M, Liu L, McGuire B (2014). Liver transplantation in the management of porphyria. Hepatology (Baltimore, Md.), 60(3), 1082-9.
- Parker CJ, Janatova J, Weis J (2000). Preface. Immunopharmacology, 49(1-2), 99-100.
- Tomita A, Radike EL, Parker C (1993). Isolation of erythrocyte membrane inhibitor of reactive lysis type II. Identification as glycophorin A. Journal of immunology (Baltimore, Md., 151(6), 3308-23.
- Holguin MH, Martin CB, Bernshaw NJ, Parker C (1992). Analysis of the effects of activation of the alternative pathway of complement on erythrocytes with an isolated deficiency of decay accelerating factor. Journal of immunology (Baltimore, Md., 148(2), 498-502.
- Parker CJ, Stone OL, Bernshaw N (1989). Characterization of the enhanced susceptibility of paroxysmal nocturnal hemoglobinuria erythrocytes to complement-mediated hemolysis initiated by cobra venom factor. Journal of immunology (Baltimore, Md., 142(1), 208-16.
- Hill HR, Bohnsack JF, Morris EZ, Augustine NH, Parker CJ, Cleary PP, Wu J (1988). Group B streptococci inhibit the chemotactic activity of the fifth component of complement. Journal of immunology (Baltimore, Md., 141(10), 3551-6.
- Bohnsack JF, Widjaja K, Ghazizadeh S, Rubens CE, Hillyard DR, Parker CJ, Albertine KH, Hill H (1997). A role for C5 and C5a-ase in the acute neutrophil response to group B streptococcal infections. The Journal of infectious diseases, 175(4), 847-55.
- Bohnsack JF, Zhou XN, Gustin JN, Rubens CE, Parker CJ, Hill H (1992). Bacterial evasion of the antibody response: human IgG antibodies neutralize soluble but not bacteria-associated group B streptococcal C5a-ase. The Journal of infectious diseases, 165(2), 315-21.
- Lassiter HA, Christensen RD, Parker C (1989). Immunologic regulation of E. coli K1 by serum from neonatal rats is enhanced following intraperitoneal administration of human IgG. The Journal of infectious diseases, 159(3), 518-25.
- Lassiter HA, Speranza MJ, Hall RT, Meade V, Christensen RD, Parker C (1990). Complement C3 deposition onto bacteria by neonatal serum is not enhanced after the infusion of intravenous immunoglobulin. Journal of perinatology, 10(1), 27-31.
- Ezzell JL, Parker C (1992). Cell-surface regulation of the human alternative pathway of complement. Sheep but not rabbit erythrocytes express factor I-dependent cofactor activity. Scandinavian journal of immunology, 36(1), 79-87.
- Gubler DB, Ahlstrom CR, Liu L, Zhou JF, Parker CJ, Rodgers G (1995). Procoagulant albumin increases vascular endothelial cell prostacyclin secretion. Thrombosis and haemostasis, 74(6), 1573-7.
- Liu L, Murray DK, Dameron CT, Parker CJ, Rodgers G (1997). Biochemical characterization of procoagulant albumin. Thrombosis research, 85(5), 399-411.
- Grosset A, Liu L, Parker CJ, Rodgers G (1994). Bioassay of procoagulant albumin in human plasma. Thrombosis research, 75(5), 551-8.
- Gubler DB, Wilson BD, Parker CJ, Rodgers G (1993). Regulation of endothelial cell protein C activation and fibrinolysis by procoagulant albumin. Thrombosis research, 70(6), 459-69.
- Parker CJ, Brodsky RA, Levine J (2009). Treatment versus transplant for challenging hematologic disorders. Biology of blood and marrow transplantation, 15(1 Suppl), 72-8.
- Parker CJ, Desnick RJ, Bissel MD, Bloomer JR, Singal A, Gouya L, Puy H, Anderson KE, Balwani M, Phillips J (2019). Results of a pilot study of isoniazid in patients with erythropoietic protoporphyria. Molecular genetics and metabolism, 128(3), 309-313.
- Thiagarajan P, Parker CJ, Prchal J (2021). How Do Red Blood Cells Die?. Frontiers in physiology, 12, 655393.
- Farrell CP, Nicolas G, Desnick RJ, Parker CJ, Lamoril J, Gouya L, Karim Z, Tchernitchko D, Chen B, Puy H, Phillips J (2021). ABCB6 Polymorphisms are not Overly Represented in Patients with Porphyria. Blood advances,
- Ventura P, Bonkovsky HL, Gouya L, Aguilera-Peiró P, Montgomery Bissell D, Stein PE, Balwani M, Anderson DKE, Parker C, Kuter DJ, Monroy S, Oh J, Ritchie B, Ko JJ, Hua Z, Sweetser MT, Sardh E, ENVISION Investigator (2022). Efficacy and safety of givosiran for acute hepatic porphyria: 24-month interim analysis of the randomized phase 3 ENVISION study. Liver international, 42(1), 161-172.
- Balwani M, Bonkovsky HL, Levy C, Anderson KE, Bissell DM, Parker C, Takahashi F, Desnick RJ, Belongie K, Endeavor Investigator (2023). Dersimelagon in Erythropoietic Protoporphyrias. The New England journal of medicine, 388(15), 1376-1385.
- Tantravahi SK, Huber BD, Vagher J, Maese L, Pomicter AD, Al-Sweel N, Asch JD, Toydemir RM, Hong B, Parker (2022). Genome-wide uniparental disomy as a mechanism of immune escape in acquired aplastic anaemia. British journal of haematology, 198(6), e78-e81.
- Langendonk JG, Balwani M, Anderson KE, Bonkovsky HL, Anstey AV, Bissell DM, Bloomer J, Edwards C, Neumann NJ, Parker C, Phillips JD, Lim HW, Hamzavi I, Deybach JC, Kauppinen R, Rhodes LE, Frank J, Murphy GM, Karstens FPJ, Sijbrands EJG, de Rooij FWM, Lebwohl M, Naik H, Goding CR, Wilson JHP, Desnick R (2015). Afamelanotide for Erythropoietic Protoporphyria. The New England journal of medicine, 373(1), 48-59.
- Everhardt T, Julian K, Benefield R, Wilson A, Wilson N, Parker CJ, Parks A, Gilreath J (2025). Platelet response following dexamethasone in obese vs nonobese patients with primary, acute immune-mediated thrombocytopenia. Research and practice in thrombosis and haemostasis, 9(3), 102844.
Review
- Parker C (2012). Paroxysmal nocturnal hemoglobinuria. Current opinion in hematology, 19(3), 141-8.
- Parker C (2011). Management of paroxysmal nocturnal hemoglobinuria in the era of complement inhibitory therapy. Hematology. American Society of Hematology. Education Program, 2011, 21-9.
- Parker, C (2011). Complement and hematology. 8(1), 5.
- Adam MP, Feldman J, Mirzaa GM, Pagon RA, Wallace SE, Bean LJH, Gripp KW, Amemiya A, Barton JC, Parker C (2024). HFE-Related Hemochromatosis. Gene Reviews,
Book Chapter
- Parker C (2015). Paroxysmal Nocturnal Hemoglobinuria.
- Parker C (2015). Complement for the Clinician.
- Parker CJ, Ware R (2014). Paroxysmal Nocturnal Hemoglobinuria.
- Parker, CJ and Ware, R (2013). Paroxysmal nocturnal hemoglobinuria. 785-808.
- Parker C (2017). Complement and PNH. 67-98.
Letter
- Trunk AD, Shewan SK, Lee CJ, Parker CJ, Couriel D (2022). Chronic graft-versus-host disease exacerbation after SARS-CoV-2 vaccination. Bone marrow transplantation, 57(3), 502-503.
- Tombul Z, Bahaj W, Ozturk M, Patel B, Toprak A, Ibrahim I, Chen W, Fuda F, Ogbue OD, Gurnari C, Parker C, Young NS, Maciejewski JP, Duran M, Bat (2024). Ahemolytic PNH (white cell PNH): Clinical features and implications of a distinct phenotype of paroxysmal nocturnal haemoglobinuria. British journal of haematology, 204(5), 2121-2124.