American Board of Anesthesiology American Board of Anesthesiology (Sub: Adult Cardiac Anesthesiology) American Board of Anesthesiology (Sub: Critical Care Medicine) National Board of Echocardiography (Advanced Perioperative TEE)

Board Certification and Academic Information

Academic Departments	Anesthesiology -Assistant Professor
Board Certification	American Board of Anesthesiology American Board of Anesthesiology (Sub: Adult Cardiac Anesthesiology) American Board of Anesthesiology (Sub: Critical Care Medicine) National Board of Echocardiography (Advanced Perioperative TEE)

Education history

Fellowship	Adult Cardiothoracic Anesthesiology - Massachusetts General Hospital, Harvard Medical School	Clinical Fellow
Fellowship	Critical Care Medicine - Massachusetts General Hospital, Harvard Medical School	Clinical Fellow
Residency	Anesthesiology - Washington University School of Medicine in St. Louis, Barnes-Jewish Hospital	Chief Resident
Residency	Anesthesiology - Washington University School of Medicine in St. Louis, Barnes-Jewish Hospital	Resident
Professional Medical	Medicine - Saba University School of Medicine	M.D., M.S.
Undergraduate	Engineering, Neuroscience, Psychology - McGill University	B.A.

Selected Publications

Journal Article

Adam W Kaplon, Sebastian Gallo, Christian S Guay, Keith H Baker (In Press.). A black swan spotted during emergence from general anaesthesia: alpha and delta oscillations present in a conversing patient. (Epub ahead of print) Br J Anaesth.
Schreier DR, Fecchio M, Guay CS, Kovacs RG, Olchanyi M, Mueller AL, Houle T, Edlow BL, Brown EN, Solt K (2025). REcovery from DEXmedetomidine-induced unresponsiveness (REDEX): a study protocol for a single center, parallel arm, non-randomized, controlled pilot trial in healthy volunteers. Nature and Science of Sleep, 17, 1259-1269.
Lang A, He D, Mueller A, Wang AA, Deng H, Houle T, Sundt T, Guay CS, Qu JZ (2025). Hypothermic Circulatory Arrest Is Associated with Increased Risk of Postoperative Delirium: A Retrospective Cohort Study. International Journal of Anesthesiology and Practice, 4(1), DOI: 10.58489/2994-2624/009.
Divya A, Guay CS, Streckenbach Scott, DAlessandro D (2025). Cor Triatriatum Sinisterum in a 67-Year-Old Presenting with Severe Mitral Regurgitation and Chronic Atrial Fibrillation. Annals of Cardiology Case Reports, 4(1), 1009.
Divya A, Guay C, Sundt TM, Bloom JP (2024). Complete Aortomitral Curtain Dehiscence Resulting in Large Pseudoaneurysm 6 Weeks After Aortic Root Replacement. JACC Case Rep, 29(22). (Read full publication)
Baum TE, Adam E, Guay CS, Schamberg G, Kazemi M, Heldt T, Brown EN (2024). Dynamic Estimation of Cardiovascular State From Arterial Blood Pressure Recordings. IEEE Trans Biomed Eng, PP. (Read full publication)
Smith SK, Kafashan MM, Rios RL, Brown EN, Landsness EC, Guay CS, Palanca BJA (2024). Daytime dexmedetomidine sedation with closed-loop acoustic stimulation alters slow wave sleep homeostasis in healthy adults. BJA Open, 10. (Read full publication)
Ellenbogen J, Guay CS (2023). Sound sleep in the intensive care unit: source-path-receiver model. Pract Neurol, 22(7), 64-7.
Clephas PRD, Hoeks SE, Singh PM, Guay CS, Trivella M, Klimek M, Heesen M (2023). Prognostic factors for chronic post-surgical pain after lung and pleural surgery: a systematic review with meta-analysis, meta-regression and trial sequential analysis. Anaesthesia, 78(8), 1005-1019. (Read full publication)
Guay CS, Bean CD, Kwon O, Brown EN (2023). Recovery From Acute Respiratory Distress Syndrome Is Associated With Increasing Alpha Power in the Frontal Electroencephalogram During Propofol Sedation: A Case Report. A A Pract, 17(7), e01698. (Read full publication)
Guay CS, Hight D, Gupta G, Kafashan M, Luong AH, Avidan MS, Brown EN, Palanca BJA (2023). Breathe-squeeze: pharmacodynamics of a stimulus-free behavioural paradigm to track conscious states during sedation(☆). Br J Anaesth, 130(5), 557-566. (Read full publication)
Nourmohammadi A, Swift JR, de Pesters A, Guay CS, Adamo MA, Dalfino JC, Ritaccio AL, Schalk G, Brunner P (2022). Passive functional mapping of receptive language cortex during general anesthesia using electrocorticography. Clin Neurophysiol, 147, 31-44. (Read full publication)
Guay CS, Kafashan M, Huels ER, Jiang Y, Beyoglu B, Spencer JW, Geczi K, Apakama G, Ju YS, Wildes TS, Avidan MS, Palanca BJA (2022). Postoperative Delirium Severity and Recovery Correlate With Electroencephalogram Spectral Features. Anesth Analg, 136(1), 140-151. (Read full publication)
Kafashan M, Brian Hickman L, Labonte AK, Huels ER, Maybrier H, Guay CS, Subramanian S, Farber NB, Ching S, Hogan RE, Kelz MB, Avidan MS, Mashour GA, Palanca BJA (2022). Quiescence during burst suppression and postictal generalized EEG suppression are distinct patterns of activity. Clin Neurophysiol, 142, 125-132. (Read full publication)
Guay CS, Khebir M, Shiva Shahiri T, Szilagyi A, Cole EE, Simoneau G, Badawy M (2021). Evaluation of automated microvascular flow analysis software AVA 4: a validation study. Intensive Care Med Exp, 9(1). (Read full publication)
Gruenbaum SE, Guay CS, Gruenbaum BF, Konkayev A, Falegnami A, Qeva E, Prabhakar H, Nunes RR, Santoro A, Garcia DP, Quiones-Hinojosa A, Bilotta F (2021). Perioperative Glycemia Management in Patients Undergoing Craniotomy for Brain Tumor Resection: A Global Survey of Neuroanesthesiologists' Perceptions and Practices. World Neurosurg, 155, e548-e563. (Read full publication)
Clephas PRD, Hoeks SE, Trivella M, Guay CS, Singh PM, Klimek M, Heesen M (2021). Prognostic factors for chronic post-surgical pain after lung or pleural surgery: a protocol for a systematic review and meta-analysis. BMJ Open, 11(6), e051554. (Read full publication)
Kafashan MM, Hyche O, Nguyen T, Smith SK, Guay CS, Wilson E, Labonte AK, Guan MJ, Lucey BP, Ju YS, Palanca BJA (2021). Perioperative sleep in geriatric cardiac surgical patients: a feasibility study using a wireless wearable device. Br J Anaesth, 126(6), e205-e208. (Read full publication)
Hickman LB, Kafashan M, Labonte AK, Chan CW, Huels ER, Guay CS, Guan MJ, Ching S, Lenze EJ, Farber NB, Avidan MS, Hogan RE, Palanca BJA (2021). Postictal generalized electroencephalographic suppression following electroconvulsive therapy: Temporal characteristics and impact of anesthetic regimen. Clin Neurophysiol, 132(4), 977-983. (Read full publication)
Guay CS, Labonte AK, Montana MC, Landsness EC, Lucey BP, Kafashan MM, Haroutounian S, Avidan MS, Brown EN, Palanca BJA (2021). Closed-loop acoustic stimulation during sedation with dexmedetomidine (Class-d): Protocol for a within-subject, crossover, controlled, interventional trial with healthy volunteers. Nat Sci Sleep, 13, 303-313. (Read full publication)
Li KM, Baddigam R, Bethel M, Guay CS, Song Z, Sullivan S, Gregory SH (2021). Anesthetic considerations for transcatheter mitral and aortic valve procedures: An introduction and overview of current literature. Curr Anesthesiol Rep, 11(3), 284-91.
Smith SK, Nguyen T, Labonte AK, Kafashan M, Hyche O, Guay CS, Wilson E, Chan CW, Luong A, Hickman LB, Fritz BA, Emmert D, Graetz TJ, Melby SJ, Lucey BP, Ju YS, Wildes TS, Avidan MS, Palanca BJA (2020). Protocol for the Prognosticating Delirium Recovery Outcomes Using Wakefulness and Sleep Electroencephalography (P-DROWS-E) study: a prospective observational study of delirium in elderly cardiac surgical patients. BMJ Open, 10(12), e044295. (Read full publication)
Fogarty AE, Guay CS, Simoneau G, Colorado BS, Segal GR, Werner JK Jr, Ellenbogen JM (2019). Head Motion Predicts Transient Loss of Consciousness in Human Head Trauma: A Case-Control Study of Mixed Martial Artists. Am J Phys Med Rehabil, 98(10), 859-865. (Read full publication)
Guay CS, Plourde G (2018). Handgrip dynamometry for continuous assessment of volitional control during induction of anesthesia: a prospective observational study. Can J Anaesth, 66(1), 48-56. (Read full publication)
Guay CS, Schanker BD (2018). Neural Correlates of Pure Experience, Anesthesia, and Meditation States. AJOB Neurosci, 9(2), 115-117. (Read full publication)
Guay CS, Ellenbogen JM (2017). Emergency Sleep Medicine. Semin Neurol, 37(4), 471-480. (Read full publication)
Guay CS, Schanker BD (2017). Brain–Computer Interfaces and Interactive Capacity in Patients With Disorders of Consciousness. AJOB Neurosci, 8(3), 141-142. (Read full publication)

Review

Li KM, Baddigam R, Bethel M, Guay CS, Song Z, Sullivan S, Gregory S (2021). Anesthesia Considerations for Transcatheter Mitral and Aortic Valve Procedures. [Review]. Curr Anesthesiol Rep, 11(3), 284-291. (Read full publication)

Book Chapter

Guay CS, Lee J (2025). Monitoring Anesthetic Brain States. In Clinical Anesthesia Procedures of the Massachusetts General Hospital (11th Edition). Wolters Kluwer.
Gruenbaum SE, Guay CS, Siller SS, Bilotta F (2019). Endocrine Management in the Neurosurgical Patient. In Prabhakar H, Ali Z (Eds.), Textbook of Neuroanesthesia and Neurocritical Care Volume II - Neurocritical Care (pp. 205-16). Singapore: Springer.

Editorial

Palanca BJA, Guay CS (2020). Associations between delirium and electroencephalographic markers: Notes from the field. Clin Neurophysiol, 132(1), 210-211. (Read full publication)
Guay CS, Avidan MS (2020). No Brain Is an Island. Anesth Analg, 130(6), 1568-1571. (Read full publication)

Letter

Palanca BJA, Kafashan M, Guay CS (2023). In Response [Letter to the editor]. Anesth Analg, 136(6), E37-E38. (Read full publication)

Research Lab

Lab link

SAND Lab