Gerald J. Gleich
( out of 13 reviews )

Gerald J. Gleich, MD

Languages spoken: English

Clinical Locations

Primary Location

Midvalley Health Center Dermatology

Dermatology
243 East 6100 South
Murray , UT 84107
801-581-2955
Get Directions

Gerald Gleich, MD is an allergist and immunologist with a practice focused on the treatment of eosinophil-associated diseases. These include asthma, esophagitis and hypereosinophilic syndromes, as well as more common allergic diseases such as allergic conjunctivitis, allergic rhinitis (hay fever), chronic rhinosinusitis, atopic dermatitis (eczema), and urticaria (hives). He is board certified in Internal Medicine, and Allergy and Immunology. His research interests are in the study of eosinophils and allergic inflammatory reactions.

Specialties

  • Allergy

Board Certification

American Board of Internal Medicine (Internal Medicine)
American Board of Allergy & Immunology
American Board of Internal Medicine (Sub: Allergy & Immun)

Patient Rating

5.0 /5
( out of 13 reviews )

The patient rating score is an average of all responses on our patient experience survey. The rating averages scores for all questions about care from our providers.

The scale on which responses are measured is 1 to 5 with 5 being the best score.

Patient Comments

Patient comments are gathered from our patient experience survey and displayed in their entirety. For the convenience of our visitors, some patient comments have been translated from their original language into English while preserving their original meaning as accurately as possible. Patients are de-identified for confidentiality and patient privacy.

UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER

Dr. Gleich explains things about my eosinophilia in a way that makes sense and helps me understand my concerns.

UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER

He is the best!! And if in his wisdom, he doesnt know the answer to something that you have asked, he looked it up with you.

UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER

Dr Gleich was very detailed in gathering information and looking at historical test results. He did not rush through the appointment, he even checked his schedule to make sure he could continue with an exam instead of making another appointment. He listened. He is very knowledgeable and took time to explain everything. So happy that I was able to get in to see him.

UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER

Very helpful with my medical problems

MIDVALLEY

We are very fortunate to have Dr Gerald Joseph Gleich at the University Of Utah. He has had a distinguished career that spans over 70 years and some say that he is the father of eosinophil research. He is instrumental helping bring life saving drugs to the market. I Thank Dr Gleich for saving my life

MIDVALLEY

The best doctor there is!

UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER

Dr. Gleich is an awesome professional. Takes the time needed with the patient. Would highly recommend him to anyone.

UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER

The doctor was 55 minutes late to my appointment

UNIVERSITY OF UTAH MIDVALLEY HEALTH CENTER

Extremely good care

Gerald Gleich, MD is an allergist and immunologist with a practice focused on the treatment of eosinophil-associated diseases. These include asthma, esophagitis and hypereosinophilic syndromes, as well as more common allergic diseases such as allergic conjunctivitis, allergic rhinitis (hay fever), chronic rhinosinusitis, atopic dermatitis (eczema), and urticaria (hives). He is board certified in Internal Medicine, and Allergy and Immunology. His research interests are in the study of eosinophils and allergic inflammatory reactions.

Board Certification and Academic Information

Academic Departments Dermatology -Research Professor
Pediatrics -Adjunct Professor
Academic Divisions Allergy / Immunology
Board Certification
American Board of Internal Medicine (Internal Medicine)
American Board of Allergy & Immunology
American Board of Internal Medicine (Sub: Allergy & Immun)

Education history

Undergraduate Premedical Sciences - University of Michigan B.A.
Professional Medical Medicine - University of Michigan M.D.
Internship Medicine - Philadelphia General Hospital Intern
Residency Internal Medicine - Jackson Memorial Hospital Resident
Fellowship Allergy & Immunology - Strong Memorial Hospital Fellow

Selected Publications

Journal Article

  1. Dong ZM, Lin E, Wechsler ME, Weller PF, Klion AD, Bochner BS, Delker DA, Hazel MW, Fairfax K, Khoury P, Akuthota P, Merkel PA, Dyer AM, Langford C, Specks U, Gleich GJ, Chinchilli VM, Raby B, Yandell M, Clayton (2020). Pulmonary Eosinophilic Granulomatosis with Polyangiitis Has IgG4 Plasma Cells and Immunoregulatory Features. The American journal of pathology, 190(7), 1438-1448.
  2. Peterson K, Lin E, Saffari H, Qeadan F, Pyne A, Firszt R, Robson J, Gleich (2020). Food-specific antibodies in oesophageal secretions: association with trigger foods in eosinophilic oesophagitis. Alimentary pharmacology & therapeutics, 52(6), 997-1007.
  3. Patel AB, Franzini A, Leroy E, Kim SJ, Pomicter AD, Genet L, Xiao M, Yan D, Ahmann JM, Agarwal AM, Clair P, Addada J, Lambert J, Salmon M, Gleich GJ, Cross NCP, Constantinescu SN, O'Hare T, Prchal JT, Deininger M (2019). JAK2 ex13InDel drives oncogenic transformation and is associated with chronic eosinophilic leukemia and polycythemia vera. Blood, 134(26), 2388-2398.
  4. Gleich GJ, Leiferman K (2009). The hypereosinophilic syndromes: current concepts and treatments. British journal of haematology, 145(3), 271-85.
  5. Gleich G (2000). Mechanisms of eosinophil-associated inflammation. The Journal of allergy and clinical immunology, 105(4), 651-63.
  6. Valent P, Klion AD, Horny HP, Roufosse F, Gotlib J, Weller PF, Hellmann A, Metzgeroth G, Leiferman KM, Arock M, Butterfield JH, Sperr WR, Sotlar K, Vandenberghe P, Haferlach T, Simon HU, Reiter A, Gleich G (2012). Contemporary consensus proposal on criteria and classification of eosinophilic disorders and related syndromes. The Journal of allergy and clinical immunology, 130(3), 607-612.e9.
  7. Saffari H, Peterson KA, Fang JC, Teman C, Gleich GJ, Pease LF 3r (2012). Patchy eosinophil distributions in an esophagectomy specimen from a patient with eosinophilic esophagitis: Implications for endoscopic biopsy. The Journal of allergy and clinical immunology, 130(3), 798-800.
  8. Steinfeld J, Bradford ES, Brown J, Mallett S, Yancey SW, Akuthota P, Cid MC, Gleich GJ, Jayne D, Khoury P, Langford CA, Merkel PA, Moosig F, Specks U, Weller PF, Wechsler M (2019). Evaluation of clinical benefit from treatment with mepolizumab for patients with eosinophilic granulomatosis with polyangiitis. The Journal of allergy and clinical immunology, 143(6), 2170-2177.
  9. Roufosse F, Kahn JE, Rothenberg ME, Wardlaw AJ, Klion AD, Kirby SY, Gilson MJ, Bentley JH, Bradford ES, Yancey SW, Steinfeld J, Gleich GJ, HES Mepolizumab study group (2020). Efficacy and safety of mepolizumab in hypereosinophilic syndrome: A phase III, randomized, placebo-controlled trial. The Journal of allergy and clinical immunology, 146(6), 1397-1405.
  10. Plager DA, Davis MD, Andrews AG, Coenen MJ, George TJ, Gleich GJ, Leiferman K (2009). Eosinophil ribonucleases and their cutaneous lesion-forming activity. Journal of immunology (Baltimore, Md., 183(6), 4013-20.
  11. Squillace DL, Checkel JL, Tefferi A, Kita H, Gleich G (2021). Development and application of novel immunoassays for eosinophil granule major basic proteins to evaluate eosinophilia and myeloproliferative disorders. Journal of immunological methods, 493, 113015.
  12. Gleich GJ, Leiferman KM, Pardanani A, Tefferi A, Butterfield J (2002). Treatment of hypereosinophilic syndrome with imatinib mesilate. Lancet (London, England), 359(9317), 1577-8.
  13. Saffari H, Peterson KA, Leiferman KM, Stabin MG, Krstyen JJ, Clayton FC, Pease LF 3rd, Yap JT, Hoffman JM, Gleich G (2020). Oral Administration of 99mTechnetium-Labeled Heparin in Eosinophilic Esophagitis. Mayo Clinic proceedings, 95(3), 449-458.
  14. Gleich GJ, Schroeter AL, Marcoux JP, Sachs MI, O'Connell EJ, Kohler P (1984). Episodic angioedema associated with eosinophilia. The New England journal of medicine, 310(25), 1621-6.
  15. Rothenberg ME, Klion AD, Roufosse FE, Kahn JE, Weller PF, Simon HU, Schwartz LB, Rosenwasser LJ, Ring J, Griffin EF, Haig AE, Frewer PI, Parkin JM, Gleich G (2008). Treatment of patients with the hypereosinophilic syndrome with mepolizumab. The New England journal of medicine, 358(12), 1215-28.
  16. Peterson KA, Gleich GJ, Limaye NS, Crispin H, Robson J, Fang J, Saffari H, Clayton F, Leiferman K (2019). Eosinophil granule major basic protein 1 deposition in eosinophilic esophagitis correlates with symptoms independent of eosinophil counts. Diseases of the esophagus, 32(11),
  17. Lee LY, Gu Q, Lin AH, Khosravi M, Gleich (2019). Airway hypersensitivity induced by eosinophil granule-derived cationic proteins. Pulmonary pharmacology & therapeutics, 57, 101804.
  18. Lin AH, Athukorala A, Gleich GJ, Lee L (2019). Cough responses to inhaled irritants are enhanced by eosinophil major basic protein in awake mice. American journal of physiology. Regulatory, integrative and comparative physiology, 317(1), R93-R97.
  19. Muraki M, Kita H, Gleich G (2020). Dexamethasone and lidocaine suppress eosinophilopoiesis from umbilical cord blood cells. Clinical and molecular allergy, 18(1), 24.
  20. Pyne AL, Hazel MW, Uchida AM, Qeadan F, Jordan KC, Holman A, Harward B, Gleich GJ, Peterson K (2022). Oesophageal secretions reveal local food-specific antibody responses in eosinophilic oesophagitis. Alimentary pharmacology & therapeutics, 56(9), 1328-1336.
  21. Rothenberg ME, Roufosse F, Faguer S, Gleich GJ, Steinfeld J, Yancey SW, Mavropoulou E, Kwon N, HES Mepolizumab Study Group (2022). Mepolizumab Reduces Hypereosinophilic Syndrome Flares Irrespective of Blood Eosinophil Count and Interleukin-5. The journal of allergy and clinical immunology. In practice, 10(9), 2367-2374.e3.
  22. Gleich GJ, Roufosse F, Chupp G, Faguer S, Walz B, Reiter A, Yancey SW, Bentley JH, Steinfeld J, HES Mepolizumab Study Group (2021). Safety and Efficacy of Mepolizumab in Hypereosinophilic Syndrome: An Open-Label Extension Study. The journal of allergy and clinical immunology. In practice, 9(12), 4431-4440.e1.
  23. Gleich GJ, Hendershot (2024). Episodic angioedema associated with eosinophilia: Benralizumab-induced complete remission. The journal of allergy and clinical immunology. In practice, 12(1), 259-261.
  24. Smith KA, Gill AS, Pollard CE, Sumsion JS, Saffari H, Ashby S, Witt BL, Shipman PA, Gabrielsen DA, Yim MT, Levy JM, Oakley GM, Orlandi RR, Gleich GJ, Alt JA, Pulsipher (2023). An eosinophil peroxidase activity assay accurately predicts eosinophilic chronic rhinosinusitis. The Journal of allergy and clinical immunology, 152(2), 400-407.

Review

  1. Gleich G (1990). The eosinophil and bronchial asthma: current understanding. The Journal of allergy and clinical immunology, 85(2), 422-36.
  2. Frigas E, Gleich G (1986). The eosinophil and the pathophysiology of asthma. The Journal of allergy and clinical immunology, 77(4), 527-37.
  3. Valent P, Klion AD, Roufosse F, Simon D, Metzgeroth G, Leiferman KM, Schwaab J, Butterfield JH, Sperr WR, Sotlar K, Vandenberghe P, Hoermann G, Haferlach T, Moriggl R, George TI, Akin C, Bochner BS, Gotlib J, Reiter A, Horny HP, Arock M, Simon HU, Gleich G (2022). Proposed Refined Diagnostic Criteria and Classification of Eosinophil Disorders and Related Syndromes. Allergy, 78(1), 47-59.
  4. Leiferman KM, Gleich G (2024). The true extent of eosinophil involvement in disease is unrecognized: the secret life of dead eosinophils. Journal of leukocyte biology, 116(2), 271-287.
  5. Chehade M, Wright BL, Atkins D, Aceves SS, Ackerman SJ, Assa'ad AH, Bauer M, Collins MH, Commins SP, Davis CM, Dellon ES, Doerfler B, Gleich GJ, Gupta SK, Hill DA, Jensen ET, Katzka D, Kliewer K, Kodroff E, Kottyan LC, Kyle S, Muir AB, Pesek RD, Peterson K, Shreffler WG, Spergel JM, Strobel MJ, Wechsler J, Zimmermann N, Furuta GT, Rothenberg M (2023). Breakthroughs in understanding and treating eosinophilic gastrointestinal diseases presented at the CEGIR/TIGERs Symposium at the 2022 American Academy of Allergy, Asthma & Immunology Meeting. The Journal of allergy and clinical immunology, 152(6), 1382-1393.

Editorial

  1. Gleich GJ, Leiferman K (2022). Does Eosinophil Depletion in Gastroenteric Diseases Associated With the Hypereosinophilic Syndrome Teach Us Whether Normal Humans Need Eosinophils in 2022?. The journal of allergy and clinical immunology. In practice, 10(6), 1606-1607.

Letter

  1. Rosenberg HF, Fryer AD, Munitz A, Bochner BS, Jacoby DB, Levi-Schaffer F, Gleich GJ, Furuta GT, Rothenberg ME, Lacy P, Fulkerson PC, Hogan SP, Ackerman SJ, Foster P (2017). In Memory and Celebration: Dr. James J. Lee. Clinical and experimental allergy, 47(7), 980-981.
  2. Ortega HG, Meyer E, Brusselle G, Asano K, Prazma CM, Albers FC, Mallett SA, Yancey SW, Gleich G (2019). Update on immunogenicity in severe asthma: Experience with mepolizumab. The journal of allergy and clinical immunology. In practice, 7(7), 2469-2475.e1.
  3. Zussman J, Gleich G (2019). Allergic rhinitis and asthma induced by boxelder bug sensitization. The journal of allergy and clinical immunology. In practice, 7(4), 1365-1366.
  4. Gleich GJ, Leiferman K (2022). Are Eosinophils Needed for Normal Health?. Mayo Clinic proceedings, 97(4), 805.
  5. Ortega H, Gleich G, Mayer B, Yancey (2015). Reproducibility of a Single Blood Eosinophil Measurement as a Biomarker in Severe Eosinophilic Asthma. Annals of the American Thoracic Society, 12(12), 1896-7.

News & Podcasts

News