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Hunter R. Underhill

Hunter R. Underhill, MD, PhD

Languages spoken: English

Clinical Locations

  • Dr. Underhill graduated with a B.S. in Mathematics from Wake Forest University in Winston-Salem, North Carolina, then he obtained an M.D. from Wake Forest University School of Medicine. After an interesting diversion that included a General Surgery internship and two-years of Neurological Surgery residency training at the University of Washington in Seattle, Dr. Underhill entered graduate school and obtained a Ph.D. in Bioengineering from the University of Washington. He then completed a residency in Clinical Medical Genetics at the University of Washington. After residency, he completed a post-doc in Tumor Biology at the University of Washington, which was supported by the NIH. He subsequently completed a fellowship in Clinical Biochemical Genetics at the University of Utah. He is currently an Assistant Professor of Pediatrics at the University of the Utah in the Division of Medical Genetics. Dr. Underhill is board-certified in Medical Genetics and board-eligible in Clinical Biochemical Genetics. He has a special interest in inborn errors of metabolism, lysosomal storage disorders, and biochemical and genetic disorders that affect myelination. Dr. Underhill’s research interests include the development, translation, and application of advanced quantitative magnetic resonance imaging (MRI) techniques for studying diseases that affect white matter. He has an interest in the study of white matter in biochemical disorders, genetic disorders, brain tumors, traumatic brain injury, and neurodegenerative conditions. He also has an interest in exploiting circulating tumor DNA for early and recurrent detection of solid tumors in both adult and pediatric patients. Dr. Underhill has a particular interest in research that integrates molecular research for genotyping with MRI for phenotyping to explore relationships between changes in DNA and tumor behavior and to broaden the understanding of mutational effects on development.

    Specialties

    Board Certification

    American Board of Medical Genetics (Clinical Genetics)
    American Board of Medical Genetics and Genomics (Clinical Biochemical Genetics)
  • Dr. Underhill graduated with a B.S. in Mathematics from Wake Forest University in Winston-Salem, North Carolina, then he obtained an M.D. from Wake Forest University School of Medicine. After an interesting diversion that included a General Surgery internship and two-years of Neurological Surgery residency training at the University of Washington in Seattle, Dr. Underhill entered graduate school and obtained a Ph.D. in Bioengineering from the University of Washington. He then completed a residency in Clinical Medical Genetics at the University of Washington. After residency, he completed a post-doc in Tumor Biology at the University of Washington, which was supported by the NIH. He subsequently completed a fellowship in Clinical Biochemical Genetics at the University of Utah. He is currently an Assistant Professor of Pediatrics at the University of the Utah in the Division of Medical Genetics. Dr. Underhill is board-certified in Medical Genetics and board-eligible in Clinical Biochemical Genetics. He has a special interest in inborn errors of metabolism, lysosomal storage disorders, and biochemical and genetic disorders that affect myelination. Dr. Underhill’s research interests include the development, translation, and application of advanced quantitative magnetic resonance imaging (MRI) techniques for studying diseases that affect white matter. He has an interest in the study of white matter in biochemical disorders, genetic disorders, brain tumors, traumatic brain injury, and neurodegenerative conditions. He also has an interest in exploiting circulating tumor DNA for early and recurrent detection of solid tumors in both adult and pediatric patients. Dr. Underhill has a particular interest in research that integrates molecular research for genotyping with MRI for phenotyping to explore relationships between changes in DNA and tumor behavior and to broaden the understanding of mutational effects on development.

    Board Certification and Academic Information

    Academic Departments Pediatrics -Primary
    Radiology & Imaging Sciences -Adjunct
    Academic Divisions Medical Genetics
    Board Certification
    American Board of Medical Genetics (Clinical Genetics)
    American Board of Medical Genetics and Genomics (Clinical Biochemical Genetics)

    Education history

    Fellowship Clinical Biochemical Genetics - University of Utah School of Medicine Fellow
    Tumor Biology - University of Washington Postdoctoral Fellow
    Residency Clinical Medical Genetics - University of Washington Resident
    Bioengineering - University of Washington Ph.D.
    Postdoctoral Fellowship Radiology - University of Washington Postdoctoral Fellow
    Neurological Surgery - University of Washington Resident
    Internship General Surgery - University of Washington Intern
    Medicine - Wake Forest University School of Medicine M.D.
    Undergraduate Mathematics - Wake Forest University B.S.
    Other Training Aerospace Engineering - U.S. Naval Academy

    Selected Publications

    Patent

    1. Underhill HR (2017). Size-Selection of Cell-Free DNA for Increasing Family Size During Next-Generation Sequencing. U.S. Patent No. Provisional Patent Filed, No. 62/561,149. Washington, D.C.:U.S. Patent and Trademark Office.
    2. Kerwin WS, Underhill HR (2011). Conditional Shape Model for Image Processing. U.S. Patent No. 7,894,664. Washington, D.C.:U.S. Patent and Trademark Office.