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Kajsa E. Affolter

Kajsa E. Affolter, MD

Languages spoken: English
  • Specialties

    • Pathology, Anatomical

    Board Certification

    American Board of Pathology (Anatomic & Clinical)
    National Board of Medical Examiners
  • Board Certification and Academic Information

    Academic Departments Pathology -Primary
    Board Certification
    American Board of Pathology (Anatomic & Clinical)
    National Board of Medical Examiners

    Education history

    Chief Resident Anatomic and Clinical Pathology - University of Utah Health Sciences Chief Resident
    Anatomic and Clinical Pathology - University of Utah Health Sciences Resident
    Fellowship Gastrointestinal, Pancreatic and Hepatobiliary Pathology - University of Utah Health Sciences Fellow
    Anatomic and Clinical Pathology - University of Utah Health Sciences Resident
    Professional Medical Medicine - University of Kansas Medical Center M.D.
    Microbiology - Kansas State University B.S.

    Selected Publications

    Journal Article

    1. Boylan KE, Kanth P, Delker D, Hazel MW, Boucher KM, Affolter K, Clayton F, Evason KJ, Jedrzkiewicz J, Pletneva M, Samowitz W, Swanson E, Bronner MP (2023). Three pathologic criteria for reproducible diagnosis of colonic sessile serrated lesion versus hyperplastic polyp. Hum Pathol, 137, 25-35. (Read full article)
    2. Florou V, Elliott A, Bailey MH, Stone D, Affolter K, Soares HP, Nevala-Plagemann C, Scaife C, Walker P, Korn WM, Lou E, Shroff RT, Hosein PJ, Garrido-Laguna I (2023). Comparative Genomic Analysis of Pancreatic Acinar Cell Carcinoma (PACC) and Pancreatic Ductal Adenocarcinoma (PDAC)Unveils New Actionable Genomic Aberrations in PACC. Clin Cancer Res, 29(17), 3408-3417. (Read full article)
    3. Wilcock DM, Moore KH, Rowe L, Mahlow J, Jedrzkiewicz J, Cleary AS, Lomo L, Ruano AL, Gering M, Bradshaw D, Maughan M, Tran P, Burlingame J, Davis R, Affolter K, Albertson DJ, Adelhardt P, Kim JT, Coleman JF, Deftereos G, Gulbahce EH, Sirohi D (2023). Quantitative Imaging Analysis Fluorescence In Situ Hybridization Validation for Clinical HER2 Testing in Breast Cancer. Arch Pathol Lab Med. (Read full article)
    4. Silvis MR, Silva D, Rohweder R, Schuman S, Gudipaty S, Truong A, Yap J, Affolter K, McMahon M, Kinsey C (2023). MYC-mediated resistance to trametinib and HCQ in PDAC is overcome by CDK4/6 and lysosomal inhibition. J Exp Med, 220(3). (Read full article)
    5. Firpo MA, Boucher KM, Bleicher J, Khanderao GD, Rosati A, Poruk KE, Kamal S, Marzullo L, De Marco M, Falco A, Genovese A, Adler JM, De Laurenzi V, Adler DG, Affolter KE, Garrido-Laguna I, Scaife CL, Turco MC, Mulvihill SJ (2023). Multianalyte Serum Biomarker Panel for Early Detection of Pancreatic Adenocarcinoma. JCO Clin Cancer Inform, 7, e2200160. (Read full article)
    6. Dong Z, Barraza G, Affolter KE, Witt BL, Jedrzkiewicz J (2022). Distinguishing Gastrointestinal Leiomyomas From Muscularis Propria in Biopsy Specimens by Differential Expression of S100 Immunohistochemical Stain. Am J Clin Pathol, 159(1), 53-59. (Read full article)
    7. Hernandez S, Parra ER, Uraoka N, Tang X, Shen Y, Qiao W, Jiang M, Zhang S, Mino B, Lu W, Pandurengan R, Haymaker C, Affolter K, Scaife CL, Yip-Schneider M, Schmidt CM, Firpo MA, Mulvihill SJ, Koay EJ, Wang H, Wistuba II, Maitra A, Solis LM, Sen S (2021). Diminished Immune Surveillance during Histologic Progression of Intraductal Papillary Mucinous Neoplasms Offers a Therapeutic Opportunity for Cancer Interception. Clin Cancer Res, 28(9), 1938-1947. (Read full article)
    8. Affolter KE, Hellwig S, Nix DA, Bronner MP, Thomas A, Fuertes CL, Hamil CL, Garrido-Laguna I, Scaife CL, Mulvihill SJ, Underhill HR (2021). Detection of circulating tumor DNA without a tumor-informed search using next-generation sequencing is a prognostic biomarker in pancreatic ductal adenocarcinoma. Neoplasia, 23(9), 859-869. (Read full article)
    9. Byun S, Affolter KE, Snow AK, Curtin K, Cannon AR, Cannon-Albright LA, Thota R, Neklason DW (2021). Differential methylation of G-protein coupled receptor signaling genes in gastrointestinal neuroendocrine tumors. Sci Rep, 11(1), 12303. (Read full article)
    10. Kmeid M, Zuo C, Lagana SM, Choi WT, Lin J, Yang Z, Liu X, Westerhoff M, Fiel MI, Affolter K, Choi EK, Lee H (2020). Interobserver study on histologic features of idiopathic non-cirrhotic portal hypertension. Diagn Pathol, 15(1), 129. (Read full article)
    11. Gruhl JD, Garrido-Laguna I, Francis SR, Affolter K, Tao R, Lloyd S (2020). The impact of squamous cell carcinoma histology on outcomes in nonmetastatic pancreatic cancer. Cancer Med, 9(5), 1703-1711. (Read full article)
    12. Kinsey CG, Camolotto SA, Boespflug AM, Guillen KP, Foth M, Truong A, Schuman SS, Shea JE, Seipp MT, Yap JT, Burrell LD, Lum DH, Whisenant JR, Gilcrease GW 3rd, Cavalieri CC, Rehbein KM, Cutler SL, Affolter KE, Welm AL, Welm BE, Scaife CL, Snyder EL, McMahon M (2019). Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers. Nat Med, 25(4), 620-627. (Read full article)
    13. Kanth P, Affolter K (2018). Worming Your Way Through the Gastrointestinal Tract: A Case of Strongyloidiasis. Clin Gastroenterol Hepatol, 16(7), A33. (Read full article)
    14. Caliskan A, Kohlmann WK, Affolter KE, Downs-Kelly E, Kanth P, Bronner MP (2017). Intramucosal lipomas of the colon implicate Cowden syndrome. Mod Pathol, 31(4), 643-651. (Read full article)
    15. El Jabbour T, Ross JS, Sheehan CE, Affolter KE, Geiersbach KB, Boguniewicz A, Ainechi S, Bronner MP, Jones DM, Lee H (2017). PD-L1 protein expression in tumour cells and immune cells in mismatch repair protein-deficient and -proficient colorectal cancer: the foundation study using the SP142 antibody and whole section immunohistochemistry. J Clin Pathol, 71(1), 46-51. (Read full article)
    16. Delker DA, Wood AC, Snow AK, Samadder NJ, Samowitz WS, Affolter KE, Boucher KM, Pappas LM, Stijleman IJ, Kanth P, Byrne KR, Burt RW, Bernard PS, Neklason DW (2017). Chemoprevention with Cyclooxygenase and Epidermal Growth Factor Receptor Inhibitors in Familial Adenomatous Polyposis Patients: mRNA Signatures of Duodenal Neoplasia. Cancer Prev Res (Phila), 11(1), 4-15. (Read full article)
    17. Samadder NJ, Valentine JF, Affolter K (2017). A Rare Cause of Diarrhea and Polyposis. Gastroenterology, 153(6), 1490-1491. (Read full article)
    18. Affolter K, Samowitz W, Boynton K, Kelly ED (2017). Doxycycline-induced gastrointestinal injury. Hum Pathol, 66, 212-215. (Read full article)
    19. Affolter K, Gligorich K, Samadder NJ, Samowitz WS, Curtin K (2017). Feasibility of Large-Scale Identification of Sessile Serrated Polyp Patients Using Electronic Records: A Utah Study. Dig Dis Sci, 62(6), 1455-1463. (Read full article)
    20. Bice BD, Stephens MR, Georges SJ, Venancio AR, Bermant PC, Warncke AV, Affolter KE, Hidalgo JR, Angus-Hill ML (2016). Environmental Enrichment Induces Pericyte and IgA-Dependent Wound Repair and Lifespan Extension in a Colon Tumor Model. Cell Rep, 19(4), 760-773. (Read full article)
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