Linda S. Book
( out of 11 reviews )

Linda S. Book, MD

Languages spoken: English

Clinical Locations

Primary Location

Eccles Primary Children's Outpatient Services

81 N Mario Capecchi Drive
Salt Lake City , UT 84113
801-213-3599
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Dr. Linda Book graduated from the University Of Cincinnati College Of Medicine, completed a pediatric residency at Cincinnati Children’s Medical Center and the University of Utah followed by fellowship training in Pediatric Gastroenterology at the University of Utah. She is a Professor of Pediatrics and is the former Chief of the Division of Pediatric Gastroenterology Hepatology and Nutrition at the University Of Utah College Of Medicine. She is the Director of the Pediatric Liver Transplant Program and Liver Center at Primary Children’s Medical Center. She has over 25 years’ experience compassionately caring for infants, children and adolescents with liver disease including those needing before and after liver transplant care. She is particularly proud to be part of the Primary Children’s Hospital liver transplant team, which has one of the best patient outcomes in the U.S. Dr.Book has worked extensively at the regional and national levels to prioritize organ allocation to children and in the development of living donor liver transplantation She is interested in quality improvement and care models for in and outpatient transplant care, and the transitioning of adolescents to adult transplant care.. Her current research interests are biliary atresia, cholestatic liver disease and pediatric liver transplantation. She received the American Academy of Pediatrics Utah Chapter Service to Children Award and the American Academy of Pediatrics Murray Davidson Award, which recognizes clinical, teaching and research excellence in pediatric gastroenterology. She is recognized in the Hall of Honor of the Cincinnati Children’s Hospital Medical Center. Dr. Book has held numerous national leadership positions in the American Academy of Pediatrics, Society of Pediatric Liver Transplantation and North American Society for Pediatric Gastroenterology Hepatology and Nutrition.

Specialties

Board Certification

Pediatric Transplant Hepatolgoy - Subspecialty
American Board of Pediatrics (Pediatrics)
American Board of Pediatrics (Sub: Pediatric Gastroenterology)
National Board of Medical Examiners

Patient Rating

5.0 /5
( out of 11 reviews )

The patient rating score is an average of all responses on our patient experience survey. The rating averages scores for all questions about care from our providers. The scale on which responses are measured is 1 to 5 with 5 being the best score.

PRIMARY CHILDREN'S MEDICAL CENTER

Dr. Book is great! She's caring and always takes the time to explain things and answer all of our questions.

EXTERNAL SITE

Dr. Book and the rest of the liver clinic team are absolutely the best!!

EXTERNAL SITE

Dr. Book and the rest of the liver clinic team are absolutely the best!!

Patient comments are gathered from our patient experience survey and displayed in their entirety. For the convenience of our visitors, some patient comments have been translated from their original language into English while preserving their original meaning as accurately as possible. Patients are de-identified for confidentiality and patient privacy.

Dr. Linda Book graduated from the University Of Cincinnati College Of Medicine, completed a pediatric residency at Cincinnati Children’s Medical Center and the University of Utah followed by fellowship training in Pediatric Gastroenterology at the University of Utah. She is a Professor of Pediatrics and is the former Chief of the Division of Pediatric Gastroenterology Hepatology and Nutrition at the University Of Utah College Of Medicine. She is the Director of the Pediatric Liver Transplant Program and Liver Center at Primary Children’s Medical Center. She has over 25 years’ experience compassionately caring for infants, children and adolescents with liver disease including those needing before and after liver transplant care. She is particularly proud to be part of the Primary Children’s Hospital liver transplant team, which has one of the best patient outcomes in the U.S. Dr.Book has worked extensively at the regional and national levels to prioritize organ allocation to children and in the development of living donor liver transplantation She is interested in quality improvement and care models for in and outpatient transplant care, and the transitioning of adolescents to adult transplant care.. Her current research interests are biliary atresia, cholestatic liver disease and pediatric liver transplantation. She received the American Academy of Pediatrics Utah Chapter Service to Children Award and the American Academy of Pediatrics Murray Davidson Award, which recognizes clinical, teaching and research excellence in pediatric gastroenterology. She is recognized in the Hall of Honor of the Cincinnati Children’s Hospital Medical Center. Dr. Book has held numerous national leadership positions in the American Academy of Pediatrics, Society of Pediatric Liver Transplantation and North American Society for Pediatric Gastroenterology Hepatology and Nutrition.

Board Certification and Academic Information

Academic Departments Pediatrics -Professor
Academic Divisions Gastroenterology, Hepatology, & Nutrition
Board Certification
Pediatric Transplant Hepatolgoy - Subspecialty
American Board of Pediatrics (Pediatrics)
American Board of Pediatrics (Sub: Pediatric Gastroenterology)
National Board of Medical Examiners

Education history

Undergraduate Biology - Marietta College B.S.
Professional Medical Medicine - University of Cincinnati M.D.
Internship Pediatrics - Children's Hospital of Cincinnati Intern
Residency Pediatrics - University of Utah School of Medicine Resident
Fellowship Cystic Fibrosis - University of Utah School of Medicine Fellow
Fellowship Pediatric Gastroenterology Hepatology and Nutrition - University of Utah School of Medicine Fellow

Selected Publications

Journal Article

  1. Knackstedt ED, Anderson SG, Anand R, Mitchell J, Arnon R, Book L, Ekong U, Elisofon SA, Furuya KN, Himes R, Jain AK, Ovchinsky N, Sundaram SS, Bucuvalas J, Danziger-Isakov L, Society of Pediatric Liver Transplantatio (2024). Cytomegalovirus prophylaxis in pediatric liver transplantation: A comparison of strategies across the Society of Pediatric Liver Transplantation (SPLIT) consortium. American journal of transplantation,
  2. Kastenberg ZJ, Deneau MR, O'Brien EA, Huynh K, Book LS, Srivastava R, Jensen MK, Jaramillo CM, Guthery S (2023). Fractionated Bilirubin Among 252 892 Utah Newborns with and Without Biliary Atresia: A 15-year Historical Birth Cohort Study. The Journal of pediatrics, 257, 113339.
  3. Lopez-Verdugo F, Sanchez-Garcia J, Baraki S, Kastenberg ZJ, Sanchez-Garavito JE, Zendejas I, Alonso D, Jensen MK, Fujita S, Meyers RL, Book L, Rodriguez-Davalos M (2023). Utilization of Segmental Grafts Is Associated With Higher Transplant Rates in Pediatric Patients. The Journal of surgical research, 290, 28-35.
  4. Blachman-Braun R, Lopez-Verdugo F, Alonso D, Book L, Feola GP, Rodriguez-Davalos M (2019). Revision of meso-Rex bypass utilizing a collateral vein in a patient with portal steal phenomenon after liver transplant: A case report. International journal of surgery case reports, 60, 230-233.
  5. Jackson WD, Book L (2015). Nonalcoholic fatty liver disease and dyslipidemia: the beleagured hepatocyte. Journal of pediatric gastroenterology and nutrition, 60(3), 287.
  6. Deneau M, Book LS, Guthery SL, Jensen M (2014). Outcome after discontinuation of immunosuppression in children with autoimmune hepatitis: a population-based study. The Journal of pediatrics, 164(4), 714-719.e2.
  7. Elizabeth Parsons C, Nelson R, Book LS, Kyle Jensen (2014). Renal replacement therapy in infants and children with hepatorenal syndrome awaiting liver transplantation: a case-control study. Liver transplantation, 20(12), 1468-74.
  8. Deneau M, Jensen MK, Holmen J, Williams MS, Book LS, Guthery S (2013). Primary sclerosing cholangitis, autoimmune hepatitis, and overlap in Utah children: epidemiology and natural history. Hepatology (Baltimore, Md.), 58(4), 1392-400.
  9. Deneau M, Jensen MK, Holmen J, Williams MS, Book LS, Guthery L (2013). Primary Sclerosing Cholangitis, Autoimmune Hepatitis and Overlap in Utah Children: Epidemiology and natural History. Hepatology (Baltimore, Md.), 00(00),
  10. Rollins MD, Ward RM, Jackson WD, Mulroy CW, Sencer CP, Ying, J, Greene T, Book L (2013). Effect of decreased parenteral soybean lipid emulsion on hepatic function in infants at risk for parenteral nutrition-associated liver disease: A pilot study. Journal of pediatric surgery, 48, 1348-1356.
  11. Kim RD, Book L, Haafiz A, Schwartz JJ, Sorensen JB, Gonzalez-Peralta R (2011). Liver transplantation in a 7-month-old girl with Caroli's disease. Journal of pediatric surgery, 46(8), 1638-41.
  12. Martin SR, Alvarez F, Anand R, Song C, Yin W, SPLIT Research Grou (2011). Outcomes in children who underwent transplantation for autoimmune hepatitis. Liver transplantation, 17(4), 393-401.
  13. Jaskowski TD, Donaldson MR, Hull CM, Wilson AR, Hill HR, Zone JJ, Book L (2010). Novel screening assay performance in pediatric celiac disease and adult dermatitis herpetiformis. Journal of pediatric gastroenterology and nutrition, 51(1), 19-23.
  14. Rollins MD, Scaife ER, Jackson WD, Meyers RL, Mulroy CW, Book L (2010). Elimination of soybean lipid emulsion in parenteral nutrition and supplementation with enteral fish oil improve cholestasis in infants with short bowel syndrome. Nutrition in clinical practice, 25(2), 199-204.
  15. Donaldson MR, Book LS, Leiferman KM, Zone JJ, Neuhausen S (2008). Strongly positive tissue transglutaminase antibodies are associated with Marsh 3 histopathology in adult and pediatric celiac disease. Journal of clinical gastroenterology, 42(3), 256-60.
  16. Ng VL, Fecteau A, Shepherd R, Magee J, Bucuvalas J, Alonso E, McDiarmid S, Cohen G, Anand R, Studies of Pediatric Liver Transplantation Research Grou (2008). Outcomes of 5-year survivors of pediatric liver transplantation: report on 461 children from a north american multicenter registry. Pediatrics, 122(6), e1128-35.
  17. Garner CP, Ding YC, Steele L, Book L, Leiferman K, Zone JJ, Neuhausen S (2007). Genome-wide linkage analysis of 160 North American families with celiac disease. Genes and immunity, 8(2), 108-14.
  18. Donaldson MR, Firth SD, Wimpee H, Leiferman KM, Zone JJ, Horsley W, O'Gorman MA, Jackson WD, Neuhausen SL, Hull CM, Book L (2007). Correlation of duodenal histology with tissue transglutaminase and endomysial antibody levels in pediatric celiac disease. Clinical gastroenterology and hepatology, 5(5), 567-73.
  19. Tsou VM, Baker R, Book L, Hammo AH, Soffer EF, Wang W, Comer G (2006). Multicenter, randomized, double-blind study comparing 20 and 40 mg of pantoprazole for symptom relief in adolescents (12 to 16 years of age) with gastroesophageal reflux disease (GERD). Clinical pediatrics, 45(8), 741-9.
  20. Donaldson M, Book L, Zone J, Neuhausen (2006). Strongly Positive Tissue Transglutaminase Antibodies Are Associated With Marsh 3 Histopathology in Adult and Pediatric Disease. Journal of clinical gastroenterology,
  21. Meyers RL, Book LS, O'Gorman MA, White KW, Jaffe RB, Feola PG, Hedlund G (2004). Percutaneous cholecysto-cholangiography in the diagnosis of obstructive jaundice in infants. Journal of pediatric surgery, 39(1), 16-8.
  22. Book L, Zone JJ, Neuhausen S (2003). Prevalence of celiac disease among relatives of sib pairs with celiac disease in U.S. families. The American journal of gastroenterology, 98(2), 377-81.
  23. Meyers R, Book L, O'Gorman M, Jackson D, Black R, Downey E, Johnson D, Matlak M, Scaife (2003). High dose Steroids, Ursodeoxycholic Acid, and Chronic IV Antibiotics Improve Bile Flow after Kasai Procedure in Infants with Biliary Atresia. Journal of pediatric surgery, 38(3), 406-411.
  24. Meyers RL, Book LS, O'Gorman MA, Jackson WD, Black RE, Johnson DG, Matlak M (2003). High-dose steroids, ursodeoxycholic acid, and chronic intravenous antibiotics improve bile flow after Kasai procedure in infants with biliary atresia. Journal of pediatric surgery, 38(3), 406-11.
  25. Lowichik A, Book (2003). Pediatric Celiac Disease: Clinicopathologic and Genetic Aspects. Pediatric and developmental pathology,
  26. Book L, Lowichik (2003). Pediatric Celiac disease in the 21st century. XXIV(9), 325-333.
  27. Neuhausen SL, Feolo M, Camp NJ, Farnham J, Book L, Zone J (2002). Genome-wide linkage analysis for celiac disease in North American families. American journal of medical genetics, 111(1), 1-9.
  28. Book L (2002). Diagnosing celiac disease in 2002: who, why, and how?. Pediatrics, 109(5), 952-4.
  29. Book L, Hart A, Black J, Feolo M, Zone JJ, Neuhausen S (2001). Prevalence and clinical characteristics of celiac disease in Downs syndrome in a US study. American journal of medical genetics, 98(1), 70-4.
  30. Neuhausen SL, Feolo M, Farnham J, Book L, Zone J (2001). Linkage analysis of HLA and candidate genes for celiac disease in a North American family-based study. BMC medical genetics, 2(1), 12.
  31. Lewis C, Book L, Black J, Sawitzke A, Cannon-Albright L, Zone J, Neuhausen (2000). Celiac disease and human leukocyte antigen genotype: accuracy of diagnosis in self-diagnosed individuals, dosage effect, and sibling risk. Journal of pediatric gastroenterology and nutrition, 31(1), 22-7.
  32. Bousvaros A, Leichtner AM, Book L, Shigeoka A, Bilodeau J, Semeao E, Ruchelli E, Mulberg A (1996). Treatment of pediatric autoimmune enteropathy with tacrolimus (FK506). Gastroenterology, 111(1), 237-43.

Review

  1. Ables C, Jaramillo C, Wood EL, Stern S, Alashari M, Book L, Butterfield R (2024). Subacute liver injury in two young infants following gene replacement therapy for spinal muscular atrophy. Molecular therapy. Methods & clinical development, 32(3), 101296.
  2. Lowichik A, Book (2003). Pediatric celiac disease: clinicopathologic and genetic aspects. Pediatric and developmental pathology, 6(6), 470-83.

Book Chapter

  1. Book (2002). Ascites and Peritonitis in Children.
  2. Book (2002). Abdominal Distention in Children.
  3. Book (2002). Abdominal Pain in Children.
  4. Book (2002). Viral Hepatitis and Cholecystitis in Children.

Case Report

  1. Martin T, Schwartz J, Demetris A, Comstock J, Lowichik A, Book (2011). Plasmapheresis treatment of antibody-mediated rejection in an A2 donor to O pediatric liver transplant recipient. Pediatric transplantation, 15(1), E15-8.

Abstract

  1. Gunasekaran T, Pan W, Torres-Pinedo R, Book L, Gremse D, Steffen R, Czinn S, Chiu Y, Pilmer B, Fitzgerald (2000). Pharmacokinetics of Lansoprazole in Adolescent Patients with Gastroesophageal Reflux Disease (GERD). Presented at the American Gastroenterology Association: May 10th. Gastroenterology, 118(4), 5683.
  2. Neuhausen S, Book L, Black J, Feola G, Farnham J, Zone (2000). Linkage Study of Eleven Candidate Genes with Association of 7P15-P14 in Celiac Disease in a U.S. Family-Based Study. Presented to the World Congress of Pediatric Gastroenterology and Nutrition: August 5th. Journal of pediatric gastroenterology and nutrition, 31(2), 1079.