Matthew Gumbleton
( out of 37 reviews )

Matthew Gumbleton, MD, PhD

Languages spoken: English

Clinical Locations

Huntsman Cancer Institute - Cancer Hospital South

Clinic 1A, Thoracic
Salt Lake City
801-587-4470

  • Specialties

    Board Certification

    American Board of Internal Medicine (Internal Medicine)
    American Board of Internal Medicine (Sub: Medical Oncology)
    National Board of Medical Examiners

    Patient Rating

    5.0 /5
    ( out of 37 reviews )

    The patient rating score is an average of all responses on our patient experience survey. The rating averages scores for all questions about care from our providers.

    The scale on which responses are measured is 1 to 5 with 5 being the best score.

    Patient Comments

    Patient comments are gathered from our patient experience survey and displayed in their entirety. For the convenience of our visitors, some patient comments have been translated from their original language into English while preserving their original meaning as accurately as possible. Patients are de-identified for confidentiality and patient privacy.

    March 26, 2025
    HUNTSMAN CANCER CENTER

    Very caring. Explaining what my problem is and acting fast on the issue. Made me very comfortable.

    February 23, 2025
    HUNTSMAN CANCER CENTER

    Thank you for listening, understanding what the patient wants and not saying no this is what will work I was not willing to do some treatments,but I'm more at ease. Thank you

    October 29, 2024
    HUNTSMAN CANCER CENTER

    Dr. Gumbleton is an asset to The Huntsman Center. I am very lucky to have a caring and intelligent Oncologist. He listens and explains.

    October 19, 2024
    HUNTSMAN CANCER CENTER

    Dr. Gumbleton is the best. He is very caring and attentive. He takes the time to explain everything without condescension, and I feel no rush. He is one of my favorite doctors. I wish they all were like him.

    September 23, 2024
    HUNTSMAN CANCER CENTER

    Dr. Gumbleton is a great doctor!!

    September 22, 2024
    HUNTSMAN CANCER CENTER

    Dr. Gumbelton is very knowledgeable in his field. He helped me to understand exactly what would be done. Very outgoing, friendly and makes you feel like he cares.

    September 09, 2024
    HUNTSMAN CANCER CENTER

    This doctor is an excellent doctor. He knew all the answers to any of the questions that was ask to the best of his ability. He never made me feel like I was a lost cause because of my illness. Very positive for helping me to maintain my positivity. I would recommend him to any one with the same disease that I have.

    July 21, 2024
    HUNTSMAN CANCER CENTER

    Dr. Gumbleton took his time in explaining things to us; if there was anything that wasn't understood, he explained it a second time. He provided hand-written charts to help. He 'prodded' us for any questions that we perhaps hadn't thought of. All with a very professional attitude but so very friendly and kind. This is a difficult position to be in and he made it somewhat less stressful. The way he handled things and worked with us was very much appreciated. He has the extra-special personality that is necessary in the type of work he does. I would recommend Dr. Gumbleton to anyone, anywhere, with absolutely no qualms. I look forward to continuing to deal with him.

    June 09, 2024
    HUNTSMAN CANCER CENTER

    The only shortcoming I experienced was that I had, at times, difficulty understanding some of what he was saying due mostly to my very poor hearing

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  • Board Certification and Academic Information

    Academic Departments Internal Medicine -Visiting Instructor
    Academic Divisions Oncology
    Board Certification
    American Board of Internal Medicine (Internal Medicine)
    American Board of Internal Medicine (Sub: Medical Oncology)
    National Board of Medical Examiners

    Education history

    Postdoctoral Fellowship Lung Cancer - Huntsman Cancer Institute Postdoctoral Research Fellow
    Fellowship Medical Oncology - Huntsman Cancer Institute Fellow
    Residency Internal Medicine - University of Utah School of Medicine Resident
    Internship Internal Medicine - University of Utah School of Medicine Clinical Internship
    Professional Medical Microbiology & Immunology - SUNY Upstate Medical University Norton College of Medicine M.D., Ph.D.
    Undergraduate Microbiology & Immunology - Kalamazoo College B.S.

    Selected Publications

    Journal Article

    1. Gumbleton M, Allan S, Conway H, Boucher K, Marvin J, Hawks J, Burnett W, Van Brocklin M, Whisenant J, Gilcrease G, Gupta S (2023). A phase I open-label study of the safety and efficacy of apatinib (rivoceranib) administered to patients with advanced malignancies to improve sensitivity to pembrolizumab in the second- or later-line setting (APPEASE). BMC Res Notes, 16(1), 16. (Read full article)
    2. Gumbleton M, Sudan R, Fernandes S, Engelman RW, Russo CM, Chisholm JD, Kerr WG (2017). Dual enhancement of T and NK cell function by pulsatile inhibition of SHIP1 improves antitumor immunity and survival. Sci Signal, 10(500). (Read full article)
    3. Iyer S, Brooks R, Gumbleton M, Kerr WG (2015). SHIP1-expressing mesenchymal stem cells regulate hematopoietic stem cell homeostasis and lineage commitment during aging. Stem Cells Dev, 24(9), 1073-81. (Read full article)
    4. Gumbleton M, Vivier E, Kerr WG (2015). SHIP1 intrinsically regulates NK cell signaling and education, resulting in tolerance of an MHC class I-mismatched bone marrow graft in mice. J Immunol, 194(6), 2847-54. (Read full article)
    5. Fernandes S, Brooks R, Gumbleton M, Park MY, Russo CM, Howard KT, Chisholm JD, Kerr WG (2015). SHIPi Enhances Autologous and Allogeneic Hematolymphoid Stem Cell Transplantation. EBioMedicine, 2(3), 205-213. (Read full article)
    6. Gumbleton M, Kerr WG (2013). Role of inositol phospholipid signaling in natural killer cell biology. Front Immunol, 4, 47. (Read full article)
    7. Fuhler GM, Brooks R, Toms B, Iyer S, Gengo EA, Park MY, Gumbleton M, Viernes DR, Chisholm JD, Kerr WG (2012). Therapeutic potential of SH2 domain-containing inositol-5'-phosphatase 1 (SHIP1) and SHIP2 inhibition in cancer. Mol Med, 18(1), 65-75. (Read full article)
    8. Puel A, Cypowyj S, Bustamante J, Wright JF, Liu L, Lim HK, Migaud M, Israel L, Chrabieh M, Audry M, Gumbleton M, Toulon A, Bodemer C, El-Baghdadi J, Whitters M, Paradis T, Brooks J, Collins M, Wolfman NM, Al-Muhsen S, Galicchio M, Abel L, Picard C, Casanova JL (2011). Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. Science, 332(6025), 65-8. (Read full article)

    Patent

    1. William K, Gumbleton M (2020). Ship inhibition to induce activation of natural killer cells. U.S. Patent No. WO2015195812. Washington, D.C.:U.S. Patent and Trademark Office.