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Specialties
- Molecular Pathology
Board Certification
American Board of Pathology (Clinical Path)National Board of Medical Examiners -
Board Certification and Academic Information
Academic Departments Pathology -Primary Board Certification American Board of Pathology (Clinical Path)National Board of Medical ExaminersEducation history
Residency Pathology - University of Utah School of Medicine Resident Pathology - Carl T. Wittwer, MD, PhD Research Fellow Professional Medical Medicine - University of Utah M.D. Biology - University of Utah B.S. Selected Publications
Journal Article
- Caan BJ, Sweeney C, Habel LA, Kwan ML, Kroenke CH, Weltzien EK, Quesenberry CP Jr, Castillo A, Factor RE, Kushi LH, Bernard PS (2014). Intrinsic subtypes from the PAM50 gene expression assay in a population-based breast cancer survivor cohort: prognostication of short- and long-term outcomes. Cancer Epidemiol Biomarkers Prev, 23(5), 725-34. (Read full article)
- Won JR, Gao D, Chow C, Cheng J, Lau SY, Ellis MJ, Perou CM, Bernard PS, Nielsen TO (2013). A survey of immunohistochemical biomarkers for basal-like breast cancer against a gene expression profile gold standard. Mod Pathol, 26(11), 1438-50. (Read full article)
- Wilkerson MD, Schallheim JM, Hayes DN, Roberts PJ, Bastien RR, Mullins M, Yin X, Miller CR, Thorne LB, Geiersbach KB, Muldrew KL, Funkhouser WK, Fan C, Hayward MC, Bayer S, Perou CM, Bernard PS (2013). Prediction of lung cancer histological types by RT-qPCR gene expression in FFPE specimens. J Mol Diagn, 15(4), 485-97. (Read full article)
- Martin M, Prat A, Rodriguez-Lescure A, Caballero R, Ebbert MT, Munarriz B, Ruiz-Borrego M, Bastien RR, Crespo C, Davis C, Rodriguez CA, Lopez-Vega JM, Furio V, Garcia AM, Casas M, Ellis MJ, Berry DA, Pitcher BN, Harris L, Ruiz A, Winer E, Hudis C, Stijleman IJ, Tuck DP, Carrasco E, Perou CM, Bernard PS (2013). PAM50 proliferation score as a predictor of weekly paclitaxel benefit in breast cancer. Breast Cancer Res Treat, 138(2), 457-66. (Read full article)
- Prat A, Cheang MC, Martin M, Parker JS, Carrasco E, Caballero R, Tyldesley S, Gelmon K, Bernard PS, Nielsen TO, Perou CM (2013). Prognostic significance of progesterone receptor-positive tumor cells within immunohistochemically defined luminal A breast cancer. J Clin Oncol, 31(2), 203-9. (Read full article)
- Ma CX, Ellis MJ, Petroni GR, Guo Z, Cai SR, Ryan CE, Craig Lockhart A, Naughton MJ, Pluard TJ, Brenin CM, Picus J, Creekmore AN, Mwandoro T, Yarde ER, Reed J, Ebbert M, Bernard PS, Watson M, Doyle LA, Dancey J, Piwnica-Worms H, Fracasso PM (2013). A phase II study of UCN-01 in combination with irinotecan in patients with metastatic triple negative breast cancer. Breast Cancer Res Treat, 137(2), 483-92. (Read full article)
- Prat A, Parker JS, Fan C, Cheang MC, Miller LD, Bergh J, Chia SK, Bernard PS, Nielsen TO, Ellis MJ, Carey LA, Perou CM (2012). Concordance among gene expression-based predictors for ER-positive breast cancer treated with adjuvant tamoxifen. Ann Oncol, 23(11), 2866-73. (Read full article)
- Bastien RR, Rodriguez-Lescure A, Ebbert MT, Prat A, Munarriz B, Rowe L, Miller P, Ruiz-Borrego M, Anderson D, Lyons B, Alvarez I, Dowell T, Wall D, Segui MA, Barley L, Boucher KM, Alba E, Pappas L, Davis CA, Aranda I, Fauron C, Stijleman IJ, Palacios J, Anton A, Carrasco E, Caballero R, Ellis MJ, Nielsen TO, Perou CM, Astill M, Bernard PS, Martin M (2012). PAM50 breast cancer subtyping by RT-qPCR and concordance with standard clinical molecular markers. BMC Med Genomics, 5, 44. (Read full article)
- Smith BA, Shelton DN, Kieffer C, Milash B, Usary J, Perou CM, Bernard PS, Welm BE (2012). Targeting the PyMT Oncogene to Diverse Mammary Cell Populations Enhances Tumor Heterogeneity and Generates Rare Breast Cancer Subtypes. Genes Cancer, 3(9-10), 550-63. (Read full article)
- Chia SK, Bramwell VH, Tu D, Shepherd LE, Jiang S, Vickery T, Mardis E, Leung S, Ung K, Pritchard KI, Parker JS, Bernard PS, Perou CM, Ellis MJ, Nielsen TO (2012). A 50-gene intrinsic subtype classifier for prognosis and prediction of benefit from adjuvant tamoxifen. Clin Cancer Res, 18(16), 4465-72. (Read full article)
- Carey LA, Rugo HS, Marcom PK, Mayer EL, Esteva FJ, Ma CX, Liu MC, Storniolo AM, Rimawi MF, Forero-Torres A, Wolff AC, Hobday TJ, Ivanova A, Chiu WK, Ferraro M, Burrows E, Bernard PS, Hoadley KA, Perou CM, Winer EP (2012). TBCRC 001: randomized phase II study of cetuximab in combination with carboplatin in stage IV triple-negative breast cancer. J Clin Oncol, 30(21), 2615-23. (Read full article)
- Cheang MC, Voduc KD, Tu D, Jiang S, Leung S, Chia SK, Shepherd LE, Levine MN, Pritchard KI, Davies S, Stijleman IJ, Davis C, Ebbert MT, Parker JS, Ellis MJ, Bernard PS, Perou CM, Nielsen TO (2012). Responsiveness of intrinsic subtypes to adjuvant anthracycline substitution in the NCIC.CTG MA.5 randomized trial. Clin Cancer Res, 18(8), 2402-12. (Read full article)
- Liu J, Welm B, Boucher KM, Ebbert MT, Bernard PS (2012). TRIM29 functions as a tumor suppressor in nontumorigenic breast cells and invasive ER+ breast cancer. Am J Pathol, 180(2), 839-47. (Read full article)
- Kelly CM, Bernard PS, Krishnamurthy S, Wang B, Ebbert MT, Bastien RR, Boucher KM, Young E, Iwamoto T, Pusztai L (2012). Agreement in risk prediction between the 21-gene recurrence score assay (Oncotype DX(R)) and the PAM50 breast cancer intrinsic Classifier in early-stage estrogen receptor-positive breast cancer. Oncologist, 17(4), 492-8. (Read full article)
- Ebbert MT, Bastien RR, Boucher KM, Martin M, Carrasco E, Caballero R, Stijleman IJ, Bernard PS, Facelli JC (2011). Characterization of uncertainty in the classification of multivariate assays: application to PAM50 centroid-based genomic predictors for breast cancer treatment plans. J Clin Bioinforma, 1, 37. (Read full article)
- DeRose YS, Wang G, Lin YC, Bernard PS, Buys SS, Ebbert MT, Factor R, Matsen C, Milash BA, Nelson E, Neumayer L, Randall RL, Stijleman IJ, Welm BE, Welm AL (2011). Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes. Nat Med, 17(11), 1514-20. (Read full article)
- Cannon-Albright LA, Cooper KG, Georgelas A, Bernard PS (2011). High quality and quantity Genome-wide germline genotypes from FFPE normal tissue. BMC Res Notes, 4, 159. (Read full article)
- Irvin WJ Jr, Orlowski RZ, Chiu WK, Carey LA, Collichio FA, Bernard PS, Stijleman IJ, Perou C, Ivanova A, Dees EC (2010). Phase II study of bortezomib and pegylated liposomal doxorubicin in the treatment of metastatic breast cancer. Clin Breast Cancer, 10(6), 465-70. (Read full article)
- Nielsen TO, Parker JS, Leung S, Voduc D, Ebbert M, Vickery T, Davies SR, Snider J, Stijleman IJ, Reed J, Cheang MC, Mardis ER, Perou CM, Bernard PS, Ellis MJ (2010). A comparison of PAM50 intrinsic subtyping with immunohistochemistry and clinical prognostic factors in tamoxifen-treated estrogen receptor-positive breast cancer. Clin Cancer Res, 16(21), 5222-32. (Read full article)
- Wilkerson MD, Yin X, Hoadley KA, Liu Y, Hayward MC, Cabanski CR, Muldrew K, Miller CR, Randell SH, Socinski MA, Parsons AM, Funkhouser WK, Lee CB, Roberts PJ, Thorne L, Bernard PS, Perou CM, Hayes DN (2010). Lung squamous cell carcinoma mRNA expression subtypes are reproducible, clinically important, and correspond to normal cell types. Clin Cancer Res, 16(19), 4864-75. (Read full article)
- Al-Tamimi DM, Bernard PS, Shawarby MA, Al-Amri AM, Hadi MA (2009). Distribution of molecular breast cancer subtypes in middle eastern-saudi arabian women: a pilot study. Ultrastruct Pathol, 33(4), 141-50. (Read full article)
- Cheang MC, Chia SK, Voduc D, Gao D, Leung S, Snider J, Watson M, Davies S, Bernard PS, Parker JS, Perou CM, Ellis MJ, Nielsen TO (2009). Ki67 index, HER2 status, and prognosis of patients with luminal B breast cancer. J Natl Cancer Inst, 101(10), 736-50. (Read full article)
- Parker JS, Mullins M, Cheang MC, Leung S, Voduc D, Vickery T, Davies S, Fauron C, He X, Hu Z, Quackenbush JF, Stijleman IJ, Palazzo J, Marron JS, Nobel AB, Mardis E, Nielsen TO, Ellis MJ, Perou CM, Bernard PS (2009). Supervised risk predictor of breast cancer based on intrinsic subtypes. J Clin Oncol, 27(8), 1160-7. (Read full article)
Letter
- Perou CM, Parker JS, Prat A, Ellis MJ, Bernard PS (2010). Clinical implementation of the intrinsic subtypes of breast cancer. [Letter to the editor]. Lancet Oncol, 11(8), 718-9; author reply 720-1. (Read full article)
Patent
- Bernard PS (2019). Methods and Compositions Involving Intrinsic Genes. U.S. Patent No. 21101.0068U1. Washington, D.C.:U.S. Patent and Trademark Office.
- Bernard PS (2019). Gene Expressions Profiles to Predict Breast Cancer Outcomes (2008). Serial#035052/344165.
- Bernard PS (2015). Methods of Treating Breast Cancer with Taxane Therapy. U.S. Patent No. 9,181,588. Washington, D.C.:U.S. Patent and Trademark Office.
- Bernard PS (2015). Methods of Treating Breast Cancer with Anthracycline Therapy. U.S. Patent No. 9,066,963. Washington, D.C.:U.S. Patent and Trademark Office.
- Bernard PS (2014). Molecular Diagnosis and Typing of Lung Cancer Variants. U.S. Patent No. 8,822,153. Washington, D.C.:U.S. Patent and Trademark Office.
- Bernard PS (2004). Simultaneous Screening and Identification of Sequence Alterations from Amplified Target. U.S. Patent No. 6.753.141. Washington, D.C.:U.S. Patent and Trademark Office.
- Bernard PS (2001). Solution-Based Color Compensation Adjusted for Temperature of Electronic Gains. U.S. Patent No. 6.197.520. Washington, D.C.:U.S. Patent and Trademark Office.
- Bernard PS (2000). Multiplex Genotyping Using Fluorescent Hybridization Probes. U.S. Patent No. 6.140.054. Washington, D.C.:U.S. Patent and Trademark Office.