Qinwen Mao
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Qinwen Mao, MD, PhD

Languages spoken: English

  • Specialties

    • Pathology, Anatomical

    Board Certification

    American Board of Pathology (Sub: Anatomic Path)
    American Board of Pathology (Sub: Neuropathology)

  • Board Certification and Academic Information

    Academic Departments Pathology -Primary
    Board Certification
    American Board of Pathology (Sub: Anatomic Path)
    American Board of Pathology (Sub: Neuropathology)

    Education history

    Fellowship Neuropathology - University of Texas Southwestern Medical School Clinical Fellow
    Anatomic Pathology - University of Texas Southwestern Medical School Resident
    Postdoctoral Fellowship Gene Therapy for Neurodegenerative Diseases - University of Iowa Carver College of Medicine Postdoctoral Fellow
    Physiology - Fourth Military Medical University Ph.D.
    Graduate Training Histology - Fourth Military Medical University M.S.
    Medicine - Fourth Military Medical University M.D.

    Selected Publications

    Journal Article

    1. Robinson LJ, Goold E, Cannon DM, Mendez JS, Menacho ST, Mao Q, Liu T (2024). A rare case of an adult primary intracranial sarcoma associated with a DICER1 mutation. J Neuropathol Exp Neurol, 83(5), 365-369. (Read full article)
    2. Wang J, Zhao X, Wang Q, Zheng X, Simayi D, Zhao J, Yang P, Mao Q, Xia H (2024). FAM76B regulates PI3K/Akt/NF-κB-mediated M1 macrophage polarization by influencing the stability of PIK3CD mRNA. Cell Mol Life Sci, 81(1), 107. (Read full article)
    3. Kawles A, Keszycki R, Minogue G, Zouridakis A, Ayala I, Gill N, Macomber A, Lubbat V, Coventry C, Rogalski E, Weintraub S, Mao Q, Flanagan ME, Zhang H, Castellani R, Bigio EH, Mesulam MM, Geula C, Gefen T (2024). Phenotypically concordant distribution of pick bodies in aphasic versus behavioral dementias. Acta Neuropathol Commun, 12(1), 31. (Read full article)
    4. Robinson LJ, Ferguson D, Walker C, Oliverson B, Kohler M, Revelo MP, Mao Q (2024). A rare case of fibromuscular dysplasia involving the cervicocephalic arterial tree highlighting the neuropathological findings. J Neuropathol Exp Neurol, 83(3), 209-213. (Read full article)
    5. Ravindra VM, Robinson L, Jensen H, Kurudza E, Joyce E, Ludwick A, Telford R, Youssef O, Ryan J, Bollo RJ, Iyer RR, Kestle JRW, Cheshier SH, Ikeda DS, Mao Q, Brockmeyer DL (2024). Morphological and ultrastructural investigation of the posterior atlanto-occipital membrane: Comparing children with Chiari malformation type I and controls. PLoS One, 19(1), e0296260. (Read full article)
    6. Robinson LJ, Goold E, Potter S, Quigley EP, Jensen RL, Mao Q (2023). A pleomorphic xanthoastrocytoma highlighting the morphological heterogeneity of this uncommon tumor. J Neuropathol Exp Neurol, 83(1), 61-64. (Read full article)
    7. Scholz SW, Moroz BE, Saez-Atienzar S, Chia R, Cahoon EK, Dalgard CL, American Genome Center, International Lewy Body Dementia Genomics Consortium, Freedman DM, Pfeiffer RM (2023). Association of cardiovascular disease management drugs with Lewy body dementia: a case-control study. Brain Commun, 6(1), fcad346. (Read full article)
    8. Zhu J, Yang J, Wen H, Wang M, Zheng X, Zhao J, Sun X, Yang P, Mao Q, Li Y, Xia H (2023). Expression and functional analysis of fam76b in zebrafish. Fish Shellfish Immunol, 142, 109161. (Read full article)
    9. Robinson LJ, Sudarshan D, Goold E, Comstock J, Klonoski J, Mao Q, Palmer CA, Davidson C (2023). A novel, pathogenic COL4A1 missense variant involving thrombotic microangiopathic leukoencephalopathy in a neonate. J Neuropathol Exp Neurol, 82(10), 880-883. (Read full article)
    10. Minogue G, Kawles A, Zouridakis A, Keszycki R, Macomber A, Lubbat V, Gill N, Mao Q, Flanagan ME, Zhang H, Castellani R, Bigio EH, Mesulam MM, Geula C, Gefen T (2023). Distinct Patterns of Hippocampal Pathology in Alzheimer's Disease with TDP-43. Ann Neurol. (Read full article)
    11. Zhang W, Xiao D, Mao Q, Xia H (2023). Role of neuroinflammation in neurodegeneration development. Signal Transduct Target Ther, 8(1), 267. (Read full article)
    12. Galbraith K, Vasudevaraja V, Serrano J, Shen G, Tran I, Abdallat N, Wen M, Patel S, Movahed-Ezazi M, Faustin A, Spino-Keeton M, Roberts LG, Maloku E, Drexler SA, Liechty BL, Pisapia D, Krasnozhen-Ratush O, Rosenblum M, Shroff S, Bou DR, Davidson C, Mao Q, Suchi M, North P, Hopp A, Segura A, Jarzembowski JA, Parsons L, Johnson MD, Mobley B, Samore W, McGuone D, Gopal PP, Canoll PD, Horbinski C, Fullmer JM, Farooqui MS, Gokden M, Wadhwani NR, Richardson TE, Umphlett M, Tsankova NM, DeWitt JC, Sen C, Placantonakis DG, Pacione D, Wisoff JH, Teresa Hidalgo E, Harter D, William CM, Cordova C, Kurz SC, Barbaro M, Orringer DA, Karajannis MA, Sulman EP, Gardner SL, Zagzag D, Tsirigos A, Allen JC, Golfinos JG, Snuderl M (2023). Clinical utility of whole-genome DNA methylation profiling as a primary molecular diagnostic assay for central nervous system tumors-A prospective study and guidelines for clinical testing. Neurooncol Adv, 5(1), vdad076. (Read full article)
    13. Kaivola K, Chia R, Ding J, Rasheed M, Fujita M, Menon V, Walton RL, Collins RL, Billingsley K, Brand H, Talkowski M, Zhao X, Dewan R, Stark A, Ray A, Solaiman S, Alvarez Jerez P, Malik L, Dawson TM, Rosenthal LS, Albert MS, Pletnikova O, Troncoso JC, Masellis M, Keith J, Black SE, Ferrucci L, Resnick SM, Tanaka T, American Genome Center, International LBD Genomics Consortium, International ALSFTD Consortium, PROSPECT Consortium, Topol E, Torkamani A, Tienari P, Foroud TM, Ghetti B, Landers JE, Ryten M, Morris HR, Hardy JA, Mazzini L, DAlfonso S, Moglia C, Calvo A, Serrano GE, Beach TG, Ferman T, Graff-Radford NR, Boeve BF, Wszolek ZK, Dickson DW, Chi A, Bennett DA, De Jager PL, Ross OA, Dalgard CL, Gibbs JR, Traynor BJ, Scholz SW (2023). Genome-wide structural variant analysis identifies risk loci for non-Alzheimer's dementias. Cell Genom, 3(6), 100316. (Read full article)
    14. Huang QQ, Hang Y, Doyle R, Mao Q, Fang D, Pope RM (2023). Mechanisms regulating the loss of Tregs in HUPO mice that develop spontaneous inflammatory arthritis. iScience, 26(5), 106734. (Read full article)
    15. Wang J, Gao H, Xie Y, Wang P, Li Y, Zhao J, Wang C, Ma X, Wang Y, Mao Q, Xia H (2023). Lycium barbarum polysaccharide alleviates dextran sodium sulfate-induced inflammatory bowel disease by regulating M1/M2 macrophage polarization via the STAT1 and STAT6 pathways. Front Pharmacol, 14, 1044576. (Read full article)
    16. Nelson PT, Lee EB, Cykowski MD, Alafuzoff I, Arfanakis K, Attems J, Brayne C, Corrada MM, Dugger BN, Flanagan ME, Ghetti B, Grinberg LT, Grossman M, Grothe MJ, Halliday GM, Hasegawa M, Hokkanen SRK, Hunter S, Jellinger K, Kawas CH, Keene CD, Kouri N, Kovacs GG, Leverenz JB, Latimer CS, Mackenzie IR, Mao Q, McAleese KE, Merrick R, Montine TJ, Murray ME, Myllykangas L, Nag S, Neltner JH, Newell KL, Rissman RA, Saito Y, Sajjadi SA, Schwetye KE, Teich AF, Thal DR, Tom SO, Troncoso JC, Wang SJ, White CL 3rd, Wisniewski T, Yang HS, Schneider JA, Dickson DW, Neumann M (2022). LATE-NC staging in routine neuropathologic diagnosis: an update. Acta Neuropathol, 145(2), 159-173. (Read full article)
    17. Multz RA, Spencer C, Matos A, Ajroud K, Zamudio C, Bigio E, Mao Q, Medeiros RA, Ahrendsen JT, Castellani RJ, Flanagan ME (2023). What every neuropathologist needs to know: condensed protocol work-up for clinical dementia syndromes. J Neuropathol Exp Neurol, 82(2), 103-109. (Read full article)
    18. Lilek J, Ajroud K, Feldman AZ, Krishnamachari S, Ghourchian S, Gefen T, Spencer CL, Kawles A, Mao Q, Tranovich JF, Jack CR, Mesulam MM, Reichard RR, Zhang H, Murray ME, Knopman D, Dickson DW, Petersen RC, Smith B, Ashe KH, Mielke MM, Nelson KM, Flanagan ME (2023). Accumulation of pTau231 at the Postsynaptic Density in Early Alzheimer's Disease. J Alzheimers Dis, 92(1), 241-260. (Read full article)
    19. Wu D, Wang J, Chang Y, Zhang S, Liang J, Zhao J, Yang P, Mao Q, Xia H (2022). Rutaecarpin reduces lipids by DGKθ-dependent activation of PPARα. Obesity (Silver Spring), 30(12), 2424-2439. (Read full article)
    20. Zhang D, Yong W, Movassaghi M, Rodriguez FJ, Yang I, McKeever P, Qian J, Li JY, Mao Q, Newell KL, Green RM, Welsh CT, Heaney AP (2022). Whole Exome Sequencing Identifies PHF14 Mutations in Neurocytoma and Predicts Responsivity to the PDGFR Inhibitor Sunitinib. Biomedicines, 10(11). (Read full article)
    21. Nassif C, Kawles A, Ayala I, Minogue G, Gill NP, Shepard RA, Zouridakis A, Keszycki R, Zhang H, Mao Q, Flanagan ME, Bigio EH, Mesulam MM, Rogalski E, Geula C, Gefen T (2022). Integrity of neuronal size in the entorhinal cortex is a biologic substrate of exceptional cognitive aging. J Neurosci. (Read full article)
    22. McKenzie AT, Marx GA, Koenigsberg D, Sawyer M, Iida MA, Walker JM, Richardson TE, Campanella G, Attems J, McKee AC, Stein TD, Fuchs TJ, White CL 3rd, PART working group, Farrell K, Crary JF (2022). Interpretable deep learning of myelin histopathology in age-related cognitive impairment. Acta Neuropathol Commun, 10(1), 131. (Read full article)
    23. Farrell K, Iida MA, Cherry JD, Casella A, Stein TD, Bieniek KF, Walker JM, Richardson TE, White CL, Alvarez VE, Huber BR, Dickson DW, Insausti R, Dams-OConnor K, Part Working Group, McKee AC, Crary JF (2022). Differential Vulnerability of Hippocampal Subfields in Primary Age-Related Tauopathy and Chronic Traumatic Encephalopathy. J Neuropathol Exp Neurol, 81(10), 781-789. (Read full article)
    24. Zheng X, Mi T, Wang R, Zhang Z, Li W, Zhao J, Yang P, Xia H, Mao Q (2022). Progranulin deficiency promotes persistent neuroinflammation and causes regional pathology in the hippocampus following traumatic brain injury. Glia, 70(7), 1317-1336. (Read full article)
    25. Mesulam MM, Coventry CA, Bigio EH, Sridhar J, Gill N, Fought AJ, Zhang H, Thompson CK, Geula C, Gefen T, Flanagan M, Mao Q, Weintraub S, Rogalski EJ (2021). Neuropathological fingerprints of survival, atrophy and language in primary progressive aphasia. Brain, 145(6), 2133-2148. (Read full article)
    26. Kaivola K, Shah Z, Chia R, International LBD Genomics Consortium, Scholz SW (2021). Genetic evaluation of dementia with Lewy bodies implicates distinct disease subgroups. Brain, 145(5), 1757-1762. (Read full article)
    27. Kawles A, Nishihira Y, Feldman A, Gill N, Minogue G, Keszycki R, Coventry C, Spencer C, Lilek J, Ajroud K, Coppola G, Rademakers R, Rogalski E, Weintraub S, Zhang H, Flanagan ME, Bigio EH, Mesulam MM, Geula C, Mao Q, Gefen T (2021). Cortical and subcortical pathological burden and neuronal loss in an autopsy series of FTLD-TDP-type C. Brain, 145(3), 1069-1078. (Read full article)
    28. Stanley NE, Robinson LJ, Mao Q (2022). A Novel, Heterozygous BSCL2 Variant in Association With Early-Onset Epileptic Encephalopathy. J Neuropathol Exp Neurol, 81, 377-380. (Read full article)
    29. Sukumaran M, Mao Q, Cantrell DR, Jahromi BS, Potts MB (2022). Holohemispheric Prostate Carcinoma Dural Metastasis Mimicking Subdural Hematoma: Case Report and Review of the Literature. J Neurol Surg Rep, 83(1), e23-e28. (Read full article)
    30. Muhammad N, Wang R, Li W, Zhang Z, Chang Y, Hu Y, Zhao J, Zheng X, Mao Q, Xia H (2022). A novel TanCAR targeting IL13Rα2 and EphA2 for enhanced glioblastoma therapy. Mol Ther Oncolytics, 24, 729-741. (Read full article)
    31. Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, Whitney K, Dangoor DK, Walsh H, Marcora E, Hefti MM, Casella A, Sissoko CT, Kapoor M, Novikova G, Udine E, Wong G, Tang W, Bhangale T, Hunkapiller J, Ayalon G, Graham RR, Cherry JD, Cortes EP, Borukov VY, McKee AC, Stein TD, Vonsattel JP, Teich AF, Gearing M, Glass J, Troncoso JC, Frosch MP, Hyman BT, Dickson DW, Murray ME, Attems J, Flanagan ME, Mao Q, Mesulam MM, Weintraub S, Woltjer RL, Pham T, Kofler J, Schneider JA, Yu L, Purohit DP, Haroutunian V, Hof PR, Gandy S, Sano M, Beach TG, Poon W, Kawas CH, Corrada MM, Rissman RA, Metcalf J, Shuldberg S, Salehi B, Nelson PT, Trojanowski JQ, Lee EB, Wolk DA, McMillan CT, Keene CD, Latimer CS, Montine TJ, Kovacs GG, Lutz MI, Fischer P, Perrin RJ, Cairns NJ, Franklin EE, Cohen HT, Raj T, Cobos I, Frost B, Goate A, White Iii CL, Crary JF (2021). Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathol, 143(1), 33-53. (Read full article)
    32. Zhang J, Chen H, Chen C, Liu H, He Y, Zhao J, Yang P, Mao Q, Xia H (2021). Systemic administration of mesenchymal stem cells loaded with a novel oncolytic adenovirus carrying IL-24/endostatin enhances glioma therapy. Cancer Lett, 509, 26-38. (Read full article)
    33. Gefen T, Kawles A, Makowski-Woidan B, Engelmeyer J, Ayala I, Abbassian P, Zhang H, Weintraub S, Flanagan ME, Mao Q, Bigio EH, Rogalski E, Mesulam MM, Geula C (2021). Paucity of Entorhinal Cortex Pathology of the Alzheimer's Type in SuperAgers with Superior Memory Performance. Cereb Cortex, 31(7), 3177-3183. (Read full article)
    34. Chia R, Sabir MS, Bandres-Ciga S, Saez-Atienzar S, Reynolds RH, Gustavsson E, Walton RL, Ahmed S, Viollet C, Ding J, Makarious MB, Diez-Fairen M, Portley MK, Shah Z, Abramzon Y, Hernandez DG, Blauwendraat C, Stone DJ, Eicher J, Parkkinen L, Ansorge O, Clark L, Honig LS, Marder K, Lemstra A, St George-Hyslop P, Londos E, Morgan K, Lashley T, Warner TT, Jaunmuktane Z, Galasko D, Santana I, Tienari PJ, Myllykangas L, Oinas M, Cairns NJ, Morris JC, Halliday GM, Van Deerlin VM, Trojanowski JQ, Grassano M, Calvo A, Mora G, Canosa A, Floris G, Bohannan RC, Brett F, Gan-Or Z, Geiger JT, Moore A, May P, Krger R, Goldstein DS, Lopez G, Tayebi N, Sidransky E, American Genome Center, Norcliffe-Kaufmann L, Palma JA, Kaufmann H, Shakkottai VG, Perkins M, Newell KL, Gasser T, Schulte C, Landi F, Salvi E, Cusi D, Masliah E, Kim RC, Caraway CA, Monuki ES, Brunetti M, Dawson TM, Rosenthal LS, Albert MS, Pletnikova O, Troncoso JC, Flanagan ME, Mao Q, Bigio EH, Rodrguez-Rodrguez E, Infante J, Lage C, Gonzlez-Aramburu I, Sanchez-Juan P, Ghetti B, Keith J, Black SE, Masellis M, Rogaeva E, Duyckaerts C, Brice A, Lesage S, Xiromerisiou G, Barrett MJ, Tilley BS, Gentleman S, Logroscino G, Serrano GE, Beach TG, McKeith IG, Thomas AJ, Attems J, Morris CM, Palmer L, Love S, Troakes C, Al-Sarraj S, Hodges AK, Aarsland D, Klein G, Kaiser SM, Woltjer R, Pastor P, Bekris LM, Leverenz JB, Besser LM, Kuzma A, Renton AE, Goate A, Bennett DA, Scherzer CR, Morris HR, Ferrari R, Albani D, Pickering-Brown S, Faber K, Kukull WA, Morenas-Rodriguez E, Lle A, Fortea J, Alcolea D, Clarimon J, Nalls MA, Ferrucci L, Resnick SM, Tanaka T, Foroud TM, Graff-Radford NR, Wszolek ZK, Ferman T, Boeve BF, Hardy JA, Topol EJ, Torkamani A, Singleton AB, Ryten M, Dickson DW, Chi A, Ross OA, Gibbs JR, Dalgard CL, Traynor BJ, Scholz SW (2021). Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture. Nat Genet, 53(3), 294-303. (Read full article)
    35. Dewan R, Chia R, Ding J, Hickman RA, Stein TD, Abramzon Y, Ahmed S, Sabir MS, Portley MK, Tucci A, Ibez K, Shankaracharya FNU, Keagle P, Rossi G, Caroppo P, Tagliavini F, Waldo ML, Johansson PM, Nilsson CF, American Genome Center TAGC, FALS Sequencing Consortium, Genomics England Research Consortium, International ALSFTD Genomics Consortium iAFGC, International FTD Genetics Consortium IFGC, International LBD Genomics Consortium iLBDGC, NYGC ALS Consortium, PROSPECT Consortium, Rowe JB, Benussi L, Binetti G, Ghidoni R, Jabbari E, Viollet C, Glass JD, Singleton AB, Silani V, Ross OA, Ryten M, Torkamani A, Tanaka T, Ferrucci L, Resnick SM, Pickering-Brown S, Brady CB, Kowal N, Hardy JA, Van Deerlin V, Vonsattel JP, Harms MB, Morris HR, Ferrari R, Landers JE, Chi A, Gibbs JR, Dalgard CL, Scholz SW, Traynor BJ (2020). Pathogenic Huntingtin Repeat Expansions in Patients with Frontotemporal Dementia and Amyotrophic Lateral Sclerosis. Neuron, 109(3), 448-460.e4. (Read full article)
    36. Walker JM, Richardson TE, Farrell K, Iida MA, Foong C, Shang P, Attems J, Ayalon G, Beach TG, Bigio EH, Budson A, Cairns NJ, Corrada M, Cortes E, Dickson DW, Fischer P, Flanagan ME, Franklin E, Gearing M, Glass J, Hansen LA, Haroutunian V, Hof PR, Honig L, Kawas C, Keene CD, Kofler J, Kovacs GG, Lee EB, Lutz MI, Mao Q, Masliah E, McKee AC, McMillan CT, Mesulam MM, Murray M, Nelson PT, Perrin R, Pham T, Poon W, Purohit DP, Rissman RA, Sakai K, Sano M, Schneider JA, Stein TD, Teich AF, Trojanowski JQ, Troncoso JC, Vonsattel JP, Weintraub S, Wolk DA, Woltjer RL, Yamada M, Yu L, White CL, Crary JF (2020). Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy. J Neuropathol Exp Neurol, 80(2), 102-111. (Read full article)
    37. Gefen T, Mao Q, Kohler M, Moeller S, Kawles A, Coventry C, Spencer C, Lilek J, Ajroud K, Feldman A, Flanagan M, Rogalski E, Weintraub S, Rademaker A, Geula C, Mesulam MM, Bigio E (2020). Primary Progressive Aphasia has a Unique Signature Distinct from Dementia of the Alzheimer's Type and Behavioral Variant Frontotemporal Dementia Regardless of Pathology. J Neuropathol Exp Neurol, 79(12), 1379-1381. (Read full article)
    38. Kam KL, Appin CL, Mao Q, Ikegami S, Lukas RV, Nikiforova MN, Roy S, Brat DJ, Horbinski C (2020). Is Next-Generation Sequencing Alone Sufficient to Reliably Diagnose Gliomas? J Neuropathol Exp Neurol, 79(7), 763-766. (Read full article)
    39. McCord MR, Bigio EH, Kam KL, Fischer V, Obeidin F, White CL, Brat DJ, Muller WA, Mao Q (2019). Spinocerebellar Ataxia Type 3: A Case Report and Literature Review. J Neuropathol Exp Neurol, 79(6), 641-646. (Read full article)
    40. Li Y, Li S, Li Y, Xia H, Mao Q (2019). Generation of a novel HEK293 luciferase reporter cell line by CRISPR/Cas9-mediated site-specific integration in the genome to explore the transcriptional regulation of the PGRN gene. Bioengineered, 10(1), 98-107. (Read full article)
    41. Zhu J, Wang N, Li X, Zheng X, Zhao J, Xia H, Mao Q (2019). Suppression of Progranulin Expression Leads to Formation of Intranuclear TDP-43 Inclusions In Vitro: A Cell Model of Frontotemporal Lobar Degeneration. J Neuropathol Exp Neurol, 78(12), 1124-1129. (Read full article)
    42. Zhang J, Zhao J, Mao Q, Xia H (2019). A simple, efficient and economical method for isolating and culturing human umbilical cord blood‑derived mesenchymal stromal cells. Mol Med Rep, 20(6), 5257-5264. (Read full article)
    43. Jara JH, Gautam M, Kocak N, Xie EF, Mao Q, Bigio EH, zdinler PH (2019). MCP1-CCR2 and neuroinflammation in the ALS motor cortex with TDP-43 pathology. J Neuroinflammation, 16(1), 196. (Read full article)
    44. Maniar KP, Arva N, Blanco LZ Jr, Mao Q, Morency EG, Rodriguez R, Wolniak K, Yaseen NR, Nayar R (2019). Accreditation Council for Graduate Medical Education Self-Study for Pathology: One Institution's Experience and Lessons Learned. Arch Pathol Lab Med, 143(10), 1271-1277. (Read full article)
    45. Mao Q, Zheng X, Gefen T, Rogalski E, Spencer CL, Rademakers R, Fought AJ, Kohler M, Weintraub S, Xia H, Mesulam MM, Bigio EH (2019). FTLD-TDP With and Without GRN Mutations Cause Different Patterns of CA1 Pathology. J Neuropathol Exp Neurol, 78(9), 844-853. (Read full article)
    46. Nishihira Y, Gefen T, Mao Q, Appin C, Kohler M, Walker J, Rademakers R, Rademaker A, Rogalski E, Weintraub S, Geula C, Mesulam MM, Bigio EH (2019). Revisiting the utility of TDP-43 immunoreactive (TDP-43-ir) pathology to classify FTLD-TDP subtypes. Acta Neuropathol, 138(1), 167-169. (Read full article)
    47. Zhang D, Kim SSR, Kelly DF, Asa SL, Movassaghi M, Mareninov S, Yong WH, Cloughesy TF, Rodriguez FJ, McKeever P, Qian J, Li JY, Mao Q, Newell KL, Green RM, Welsh CT, Xiong Z, Heaney AP (2018). Somatostatin Receptor Ligand Therapy-A Potential Therapy for Neurocytoma. J Clin Endocrinol Metab, 104(6), 2395-2402. (Read full article)
    48. Apple AC, Mao Q, Bigio E, Bonakdarpour B (2019). Sleep talking and primary progressive aphasia: case study and autopsy findings in a patient with logopenic primary progressive aphasia and dementia with Lewy bodies. BMJ Case Rep, 12(5). (Read full article)
    49. Rogalski E, Gefen T, Mao Q, Connelly M, Weintraub S, Geula C, Bigio EH, Mesulam MM (2018). Cognitive trajectories and spectrum of neuropathology in SuperAgers: The first 10 cases. Hippocampus, 29(5), 458-467. (Read full article)
    50. Li Y, Wang D, Li Y, Zhu J, Zhao J, Deng Y, Rogalski EJ, Bigio EH, Rademaker AW, Xia H, Mao Q (2019). A Highly Sensitive Sandwich ELISA to Detect CSF Progranulin: A Potential Biomarker for CNS Disorders. J Neuropathol Exp Neurol, 78(5), 406-415. (Read full article)
    51. Shan L, Wang D, Mao Q, Xia H (2018). Establishment of a DGKθ Endogenous Promoter Luciferase Reporter HepG2 Cell Line for Studying the Transcriptional Regulation of DGKθ Gene. Appl Biochem Biotechnol, 187(4), 1344-1355. (Read full article)
    52. Hojat A, Wei B, Olson MG, Mao Q, Yong WH (2018). Procurement and Storage of Surgical Biospecimens. Methods Mol Biol, 1897, 65-76. (Read full article)
    53. Chen H, Li Y, Du C, Li Y, Zhao J, Zheng X, Mao Q, Xia H (2018). Aptazyme-mediated direct modulation of post-transcriptional sgRNA level for conditional genome editing and gene expression. J Biotechnol, 288, 23-29. (Read full article)
    54. Li Y, Zhang W, Zhao J, Li S, Shan L, Zhu J, Li Y, Zhu H, Mao Q, Xia H (2018). Establishing a dual knock-out cell line by lentivirus based combined CRISPR/Cas9 and Loxp/Cre system. Cytotechnology, 70(6), 1595-1605. (Read full article)
    55. Li Z, Zhao J, Muhammad N, Wang D, Mao Q, Xia H (2018). Establishment of a HEK293 cell line by CRISPR/Cas9-mediated luciferase knock-in to study transcriptional regulation of the human SREBP1 gene. Biotechnol Lett, 40(11-12), 1495-1506. (Read full article)
    56. Gefen T, Ahmadian SS, Mao Q, Kim G, Seckin M, Bonakdarpour B, Ramos EM, Coppola G, Rademakers R, Rogalski E, Rademaker A, Weintraub S, Mesulam MM, Geula C, Bigio EH (2018). Combined Pathologies in FTLD-TDP Types A and C. J Neuropathol Exp Neurol, 77(5), 405-412. (Read full article)
    57. Zhang J, Zhao J, Zheng X, Cai K, Mao Q, Xia H (2017). Establishment of a novel hepatic steatosis cell model by Cas9/sgRNA-mediated DGKθ gene knockout. Mol Med Rep, 17(2), 2169-2176. (Read full article)
    58. Huang QQ, Birkett R, Doyle R, Shi B, Roberts EL, Mao Q, Pope RM (2017). The Role of Macrophages in the Response to TNF Inhibition in Experimental Arthritis. J Immunol, 200(1), 130-138. (Read full article)
    59. Zhang W, Xiao D, Shan L, Zhao J, Mao Q, Xia H (2017). Generation of apoptosis-resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production. Biotechnol Bioeng, 114(11), 2539-2549. (Read full article)
    60. Mao Q, Wang D, Li Y, Kohler M, Wilson J, Parton Z, Shmaltsuyeva B, Gursel D, Rademakers R, Weintraub S, Mesulam MM, Xia H, Bigio EH (2017). Disease and Region Specificity of Granulin Immunopositivities in Alzheimer Disease and Frontotemporal Lobar Degeneration. J Neuropathol Exp Neurol, 76(11), 957-968. (Read full article)
    61. Muhammad N, Mao Q, Xia H (2018). CAR T-cells for cancer therapy. Biotechnol Genet Eng Rev, 33(2), 190-226. (Read full article)
    62. Chen F, Li Y, Zhao J, Mao Q, Xia H (2016). Domain-Specific Monoclonal Antibodies Against Human Rev-erbβ. Appl Biochem Biotechnol, 182(3), 978-989. (Read full article)
    63. Kovacs GG, Xie SX, Lee EB, Robinson JL, Caswell C, Irwin DJ, Toledo JB, Johnson VE, Smith DH, Alafuzoff I, Attems J, Bencze J, Bieniek KF, Bigio EH, Bodi I, Budka H, Dickson DW, Dugger BN, Duyckaerts C, Ferrer I, Forrest SL, Gelpi E, Gentleman SM, Giaccone G, Grinberg LT, Halliday GM, Hatanpaa KJ, Hof PR, Hofer M, Hortobgyi T, Ironside JW, King A, Kofler J, Kvari E, Kril JJ, Love S, Mackenzie IR, Mao Q, Matej R, McLean C, Munoz DG, Murray ME, Neltner J, Nelson PT, Ritchie D, Rodriguez RD, Rohan Z, Rozemuller A, Sakai K, Schultz C, Seilhean D, Smith V, Tacik P, Takahashi H, Takao M, Rudolf Thal D, Weis S, Wharton SB, White CL 3rd, Woulfe JM, Yamada M, Trojanowski JQ (2017). Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG). J Neuropathol Exp Neurol, 76(7), 605-619. (Read full article)
    64. Li Y, Li Y, Ye M, Wang D, Zhao J, Sun X, Mao Q, Xia H (2016). Biological function analysis of monoclonal antibodies against human granulins in vitro using U251 cells as a model. Protein Expr Purif, 130, 55-62. (Read full article)
    65. Hakar M, Chandler JP, Bigio EH, Mao Q (2016). Neuroendocrine carcinoma of the pineal parenchyma. The first reported case. J Clin Neurosci, 35, 68-70. (Read full article)
    66. Li Y, Li Y, Zhao J, Zheng X, Mao Q, Xia H (2016). Development of a Sensitive Luciferase-Based Sandwich ELISA System for the Detection of Human Extracellular Matrix 1 Protein. Monoclon Antib Immunodiagn Immunother, 35(6), 273-279. (Read full article)
    67. Dai X, Li Y, Sun X, Cai K, Mao Q, Xia H (2016). Generation of Domain-Specific Monoclonal Antibodies Against Human Glutaredoxin3. Monoclon Antib Immunodiagn Immunother, 35(6), 285-292. (Read full article)
    68. Ampie L, Choy W, DiDomenico JD, Lamano JB, Williams CK, Kesavabhotla K, Mao Q, Bloch O (2016). Clinical attributes and surgical outcomes of angiocentric gliomas. J Clin Neurosci, 28, 117-22. (Read full article)
    69. Li Y, Li Y, Zhao J, Wang D, Mao Q, Xia H (2016). Production and characterization of domain-specific monoclonal antibodies against human ECM1. Protein Expr Purif, 121, 103-11. (Read full article)
    70. Zheng X, Li Y, Zhao J, Wang D, Xia H, Mao Q (2016). Production and Characterization of Monoclonal Antibodies against Human Nuclear Protein FAM76B. PLoS One, 11(3), e0152237. (Read full article)
    71. Xiao D, Zhang W, Li Y, Liu K, Zhao J, Sun X, Shan L, Mao Q, Xia H (2015). A novel luciferase knock-in reporter system for studying transcriptional regulation of the human Sox2 gene. J Biotechnol, 219, 110-6. (Read full article)
    72. Choy W, Ampie L, Lamano JB, Kesavabhotla K, Mao Q, Parsa AT, Bloch O (2015). Predictors of recurrence in the management of chordoid meningioma. J Neurooncol, 126(1), 107-116. (Read full article)
    73. Choy W, Ampie L, Lamano JB, Kesavabhotla K, Mao Q, Parsa AT, Bloch O (2015). Erratum to: Predictors of recurrence in the management of chordoid meningioma. J Neurooncol, 126(1), 117. (Read full article)
    74. Ampie L, Choy W, Lamano JB, Kesavabhotla K, Mao Q, Parsa AT, Bloch O (2015). Prognostic factors for recurrence and complications in the surgical management of primary chordoid gliomas: A systematic review of literature. Clin Neurol Neurosurg, 138, 129-36. (Read full article)
    75. Wang D, Guo Y, Li Y, Li W, Zheng X, Xia H, Mao Q (2015). Detection of CD133 expression in U87 glioblastoma cells using a novel anti-CD133 monoclonal antibody. Oncol Lett, 9(6), 2603-2608. (Read full article)
    76. Gu J, Yang T, Xing X, Kuang Y, Cheng G, Zhang J, Huang Y, Zhang B, Dong L, Mao Q (2015). A dorsally located giant posterior fossa neurenteric cyst in a Chinese woman. J Clin Neurosci, 22(5), 917-8. (Read full article)
    77. Chen H, Wang D, Xia R, Mao Q, Xia H (2015). A novel adenoviral vector carrying an all-in-one Tet-On system with an autoregulatory loop for tight, inducible transgene expression. BMC Biotechnol, 15, 4. (Read full article)
    78. Zhang W, Chen H, Zheng X, Wang D, Ji H, Xia H, Mao Q (2014). Targeted genome correction by a single adenoviral vector simultaneously carrying an inducible zinc finger nuclease and a donor template. J Biotechnol, 188, 1-6. (Read full article)
    79. Bit-Ivan EN, Lee KH, Gitelman D, Weintraub S, Mesulam M, Rademakers R, Isaacs AM, Hatanpaa KJ, White CL 3rd, Mao Q, Akman O, DiMauro S, Bigio EH (2014). Adult polyglucosan body disease with GBE1 haploinsufficiency and concomitant frontotemporal lobar degeneration. Neuropathol Appl Neurobiol, 40(6), 778-82. (Read full article)
    80. Lall RR, Lall RR, Smith TR, Lee KH, Mao Q, Kalapurakal JA, Marymont MH, Chandler JP (2013). Delayed malignant transformation of petroclival meningioma to chondrosarcoma after stereotactic radiosurgery. J Clin Neurosci, 21(7), 1225-8. (Read full article)
    81. Wang D, Li W, Zhang H, Mao Q, Xia H (2014). A targeting peptide improves adenovirus-mediated transduction of a glioblastoma cell line. Oncol Rep, 31(5), 2093-8. (Read full article)
    82. Zhang W, Wang D, Liu S, Zheng X, Ji H, Xia H, Mao Q (2014). Multiple copies of a linear donor fragment released in situ from a vector improve the efficiency of zinc-finger nuclease-mediated genome editing. Gene Ther, 21(3), 282-8. (Read full article)
    83. Chen H, Zheng X, Di B, Wang D, Zhang Y, Xia H, Mao Q (2014). Aptamer modification improves the adenoviral transduction of malignant glioma cells. J Biotechnol, 168(4), 362-6. (Read full article)
    84. Li X, Xia R, Zhao J, Wang D, Mao Q, Xia H (2013). A one-step ligation system for rapid generation of armed, conditionally-replicating adenoviruses. Biotechnol Lett, 35(8), 1215-21. (Read full article)
    85. Lall RR, Shafizadeh SF, Lee KH, Mao Q, Mehta M, Raizer J, Bendok BR, Chandler JP (2013). Orbital metastasis of pituitary growth hormone secreting carcinoma causing lateral gaze palsy. Surg Neurol Int, 4, 59. (Read full article)
    86. Bigio EH, Weintraub S, Rademakers R, Baker M, Ahmadian SS, Rademaker A, Weitner BB, Mao Q, Lee KH, Mishra M, Ganti RA, Mesulam MM (2012). Frontotemporal lobar degeneration with TDP-43 proteinopathy and chromosome 9p repeat expansion in C9ORF72: clinicopathologic correlation. Neuropathology, 33(2), 122-33. (Read full article)
    87. Lee KH, Lall RR, Chandler JP, Bigio EH, Mao Q (2012). Pineal chordoid meningioma complicated by repetitive hemorrhage during pregnancy: case report and literature review. Neuropathology, 33(2), 192-8. (Read full article)
    88. Bigio EH, Wu JY, Deng HX, Bit-Ivan EN, Mao Q, Ganti R, Peterson M, Siddique N, Geula C, Siddique T, Mesulam M (2013). Inclusions in frontotemporal lobar degeneration with TDP-43 proteinopathy (FTLD-TDP) and amyotrophic lateral sclerosis (ALS), but not FTLD with FUS proteinopathy (FTLD-FUS), have properties of amyloid. Acta Neuropathol, 125(3), 463-5. (Read full article)
    89. Zhang W, Zheng X, Wang Y, Mao Q, Xia H (2012). Establishment of a cell line carrying single copy of an exogenous mutant reporter gene for assaying the biological activity of ZFNs. J Biotechnol, 162(2-3), 191-6. (Read full article)
    90. Li X, Mao Q, Wang D, Xia H (2012). A novel Ad5/11 chimeric oncolytic adenovirus for improved glioma therapy. Int J Oncol, 41(6), 2159-65. (Read full article)
    91. Li X, Mao Q, Wang D, Zhang W, Xia H (2012). A fiber chimeric CRAd vector Ad5/11-D24 double-armed with TRAIL and arresten for enhanced glioblastoma therapy. Hum Gene Ther, 23(6), 589-96. (Read full article)
    92. Chai L, Liu S, Mao Q, Wang D, Li X, Zheng X, Xia H (2011). A novel conditionally replicating adenoviral vector with dual expression of IL-24 and arresten inserted in E1 and the region between E4 and fiber for improved melanoma therapy. Cancer Gene Ther, 19(4), 247-54. (Read full article)
    93. Di B, Mao Q, Zhao J, Li X, Wang D, Xia H (2011). A rapid generation of adenovirus vector with a genetic modification in hexon protein. J Biotechnol, 157(3), 373-8. (Read full article)
    94. Zhang W, Guo Y, Zhang C, Ji H, Meng W, Wang D, Li X, Mao Q, Xia H (2012). Rescue the failed half-ZFN by a sensitive mammalian cell-based luciferase reporter system. PLoS One, 7(9), e45169. (Read full article)
    95. Zheng X, Mao Q, Wang D, Zhao J, Xia H (2011). A novel system for rapid screening of effective siRNA target sites by one step transfection with a single vector. J Biotechnol, 155(2), 135-9. (Read full article)
    96. Chai L, Mao Q, Liu S, Xia H (2011). Domain-specific monoclonal antibodies produced against human PGRN. Hybridoma (Larchmt), 30(3), 271-8. (Read full article)
    97. Wang D, Liu S, Mao Q, Zhao J, Xia H (2011). A novel vector for a rapid generation of fiber-mutant adenovirus based on one step ligation and quick screening of positive clones. J Biotechnol, 152(3), 72-6. (Read full article)
    98. Liu S, Mao Q, Zhang W, Zheng X, Bian Y, Wang D, Li H, Chai L, Zhao J, Xia H (2008). Genetically modified adenoviral vector with the protein transduction domain of Tat improves gene transfer to CAR-deficient cells. Biosci Rep, 29(2), 103-9. (Read full article)
    99. Eliason SL, Stein CS, Mao Q, Tecedor L, Ding SL, Gaines DM, Davidson BL (2007). A knock-in reporter model of Batten disease. J Neurosci, 27(37), 9826-34. (Read full article)
    100. Passini MA, Dodge JC, Bu J, Yang W, Zhao Q, Sondhi D, Hackett NR, Kaminsky SM, Mao Q, Shihabuddin LS, Cheng SH, Sleat DE, Stewart GR, Davidson BL, Lobel P, Crystal RG (2006). Intracranial delivery of CLN2 reduces brain pathology in a mouse model of classical late infantile neuronal ceroid lipofuscinosis. J Neurosci, 26(5), 1334-42. (Read full article)
    101. Orii KO, Grubb JH, Vogler C, Levy B, Tan Y, Markova K, Davidson BL, Mao Q, Orii T, Kondo N, Sly WS (2004). Defining the pathway for Tat-mediated delivery of beta-glucuronidase in cultured cells and MPS VII mice. Mol Ther, 12(2), 345-52. (Read full article)
    102. Harper SQ, Staber PD, He X, Eliason SL, Martins IH, Mao Q, Yang L, Kotin RM, Paulson HL, Davidson BL (2005). RNA interference improves motor and neuropathological abnormalities in a Huntington's disease mouse model. Proc Natl Acad Sci U S A, 102(16), 5820-5. (Read full article)
    103. Sleat DE, Wiseman JA, El-Banna M, Kim KH, Mao Q, Price S, Macauley SL, Sidman RL, Shen MM, Zhao Q, Passini MA, Davidson BL, Stewart GR, Lobel P (2004). A mouse model of classical late-infantile neuronal ceroid lipofuscinosis based on targeted disruption of the CLN2 gene results in a loss of tripeptidyl-peptidase I activity and progressive neurodegeneration. J Neurosci, 24(41), 9117-26. (Read full article)
    104. Xia H, Mao Q, Eliason SL, Harper SQ, Martins IH, Orr HT, Paulson HL, Yang L, Kotin RM, Davidson BL (2004). RNAi suppresses polyglutamine-induced neurodegeneration in a model of spinocerebellar ataxia. Nat Med, 10(8), 816-20. (Read full article)
    105. Mao Q, Xia H, Davidson BL (2003). Intracellular trafficking of CLN3, the protein underlying the childhood neurodegenerative disease, Batten disease. FEBS Lett, 555(2), 351-7. (Read full article)
    106. Kim M, Mao Q, Davidson BL, Wiemer DF (2003). Tripeptide probes for tripeptidyl protease I production via gene transfer. J Med Chem, 46(9), 1603-8. (Read full article)
    107. Mao Q, Foster BJ, Xia H, Davidson BL (2003). Membrane topology of CLN3, the protein underlying Batten disease. FEBS Lett, 541(1-3), 40-6. (Read full article)
    108. Xia H, Mao Q, Paulson HL, Davidson BL (2002). siRNA-mediated gene silencing in vitro and in vivo. Nat Biotechnol, 20(10), 1006-10. (Read full article)
    109. Xia H, Mao Q, Davidson BL (2001). The HIV Tat protein transduction domain improves the biodistribution of beta-glucuronidase expressed from recombinant viral vectors. Nat Biotechnol, 19(7), 640-4. (Read full article)
    110. Zhang LF, Yu ZB, Ma J, Mao QW (2001). Peripheral effector mechanism hypothesis of postflight cardiovascular dysfunction. Aviat Space Environ Med, 72(6), 567-75. (Read full article)
    111. Zhang LF, Yu ZB, Ma J, Mao QW (2003). [Peripheral effector mechanism hypothesis on cardiovascular dysfunction after spaceflight]. Sheng Li Ke Xue Jin Zhan, 32(1), 13-7. (Read full article)
    112. Xia H, Anderson B, Mao Q, Davidson BL (2000). Recombinant human adenovirus: targeting to the human transferrin receptor improves gene transfer to brain microcapillary endothelium. J Virol, 74(23), 11359-66. (Read full article)
    113. Mao QW, Zhang LF, Zhang LN, Ma J (2001). [Ultrastructural changes of arterial wall from different body parts of rats during simulated weightlessness]. Space Med Med Eng (Beijing), 12(4), 249-53. (Read full article)
    114. Mao QW, Zhang LF, Ma J (2002). [Changes in lumen diameters of vessels in arteriolar network in rat soleus muscle after simulated weightlessness]. Space Med Med Eng (Beijing), 12(3), 177-80. (Read full article)
    115. Mao QW, Zhang LF, Ma J (2002). [Differentiated remodeling changes of medium-sized arteries from different body parts in tail-suspended rats and their reversibility]. Space Med Med Eng (Beijing), 12(2), 92-6. (Read full article)
    116. Mao QW, Zhang LF, Ma J (1997). Observations on arteriolar network structure in soleus of tail-suspended rats. J Gravit Physiol, 4(2), P129-30. (Read full article)
    117. Zhang LF, Mao QW, Ma J, Yu ZB (1996). Effects of simulated weightlessness on arterial vasculature (an experimental study on vascular deconditioning). J Gravit Physiol, 3(2), 5-8. (Read full article)