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Huntsman Cancer Institute

Why Choose Us for Your Lymphoma Treatment

Huntsman Cancer Institute is nationally recognized as a leader in the research and treatment of lymphomas, including Hodgkin and Non-Hodgkin lymphomas.

Our Hematologic Cancers Care Team focuses on understanding the biology of all lymphoid cancers, and we offer a wide range of cutting-edge treatments for patients, including immunotherapy, targeted therapy, and cellular therapies.

Patients benefit from a collaborative approach to care, with a multidisciplinary team that includes medical oncologists, hematologists, radiation oncologists, and hematopathologists. This ensures comprehensive and personalized treatment plans tailored to each patient's unique needs.

Specialized Treatment

We offer a comprehensive array of specialized treatments for lymphoma patients, tailored to address the unique characteristics of each subtype. Key treatments include the following:

Chemotherapy

Chemotherapy employs drugs to destroy cancer cells or inhibit their proliferation. Our chemotherapy regimens are customized based on the specific type and stage of lymphoma, ensuring optimal effectiveness. 

Radiation Therapy

This treatment uses high-energy radiation to target and eliminate cancer cells. Our advanced radiation techniques focus on minimizing exposure to surrounding healthy tissues, thereby reducing potential side effects.

Targeted Therapy

Targeted therapies are designed to interfere with specific molecules involved in cancer cell growth and survival. We utilize targeted agents such as Bruton’s tyrosine kinase inhibitors, which have demonstrated effectiveness in treating certain lymphoma subtypes and CLL.

Stem Cell Transplantation

Stem cell transplantation involves replacing diseased bone marrow with healthy stem cells to restore normal blood cell production. This procedure can be autologous (using the patient's own cells) or allogeneic (using donor cells), depending on individual circumstances.

Immunotherapy

Immunotherapy enhances the body's immune system to recognize and combat cancer cells. We offer various immunotherapeutic approaches, including the following:

  • Chimeric Antigen Receptor T-Cell (CAR T-cell) Therapy: This innovative treatment involves modifying a patient's own T cells to recognize and attack lymphoma cells. Our CAR T-cell therapies have shown efficacy in treating certain types of non-Hodgkin lymphoma.
  • Monoclonal Antibodies: These laboratory-produced molecules can bind to specific targets on cancer cells, marking them for destruction by the immune system. Examples include rituximab and obinutuzumab, which target the CD20 protein on B-cell lymphomas.
  • Bispecific Antibodies: This novel immunotherapy binds to two targets at once, typically one on cancer cells and one on immune cells, redirecting T cells to recognize and attack lymphoma cells.

Our Expertise

We are a leading center for the diagnosis, treatment, and research of lymphomas and CLL. Our multidisciplinary team includes specialists with expertise in various lymphoma subtypes, and our Hematological Malignancies and Hematology Center has a wide variety of clinical trials for lymphoma and CLL patients focused on developing innovative treatments, exploring new therapy combinations, and identifying novel therapeutic targets, all with the hope of improving outcomes for patients with lymphoid malignancies.

Patient Care Philosophy

We believe no one should face cancer alone. Our dedicated and world-renowned doctors, nurses, and medical staff are at the forefront of patient-centered care. We treat the whole person, not just their cancer.

Each day, our medical, surgical, and radiation oncologists work together across disciplines to create and coordinate treatment plans for every patient. We understand cancer is a complex disease. That is why we use a team approach that includes social workers and support groups, as well as wellness and integrative health services such as acupuncture, massage, creative arts, and more.

Find a Lymphoma Doctor

Lymphoma Cancer Research

Our research group at Huntsman Cancer Institute is committed to conducting groundbreaking clinical research that will benefit our patients and change the treatment landscape for lymphoma and CLL. We actively conduct clinical trials to explore novel treatments for lymphoma and CLL and have led more than 50 Phase 1, 2, and 3 clinical trials. Our work has contributed to the development and FDA approval of targeted therapies, bispecific antibodies, novel therapy combinations and CAR T-cell therapies for lymphoma and CLL patients.

Clinical trials aid in the discovery of new innovative therapies that aim to be more efficacious with potentially less toxicities than previously approved treatments. Many patients in the past participated in clinical trials that have led to the currently available treatments we will be discussing with you and what we consider our “standards of care.” However, the clinical trials your lymphoma/CLL team currently have available aim to improve and add to the standard of care. If you are interested in hearing more about what clinical trials may be available to you, please ask your lymphoma/CLL team.

Make an Appointment with a Lymphoma Specialist

To make an appointment with a lymphoma specialist, fill out our appointment form or call 801-587-7000. Our team will determine if your insurance covers treatment at Huntsman Cancer Institute or if you need a referral from a primary care doctor.

External providers can refer a patient using the online referral form or by calling 801-587-7000 to speak to a patient registration specialist.

Lymphoma Basics

The lymphatic system includes lymph nodes, the spleen, thymus gland, and bone marrow. Lymphomas primarily affect a type of white blood cell known as lymphocytes, which help the body fight infections.

Hodgkin lymphoma and non-Hodgkin lymphoma are the two main types of lymphomas.

Hodgkin Lymphoma

Hodgkin lymphoma is a disease where cancer cells form in the lymph system and is identified by the presence of Hodgkin lymphoma cancer cells called Reed-Sternberg cells. There are two types of adult Hodgkin lymphoma: classical and nodular lymphocyte-predominant.

Non-Hodgkin Lymphoma

Non-Hodgkin lymphoma is a disease where cancer cells form in the lymph system, and unlike Hodgkin lymphoma, Reed-Sternberg cells are not present. Non-Hodgkin lymphoma can begin in cells called B lymphocytes, T lymphocytes, or natural killer cells.

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